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All Journal International Journal of Public Health Science (IJPHS) Majalah Obat Tradisional
Suwandi, Nur Rohmah
Unknown Affiliation
Health Professions Medicine & Pharmacology Public Health

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The Ameliorative Effects of Phyllanthus gomphocarpus Hook. F. on Sperm Parameters of Rats Induced with Bisphenol A Kamarudin, Evana; Dasiman, Razif; Bahari, Ebby Anuar; Daud, Kamalru Azman; Suwandi, Nur Rohmah
Majalah Obat Tradisional Vol 28, No 3 (2023)
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/mot.84823

Abstract

Infertility due to poor sperm quality is a common problem nowadays, particularly in developed countries. Herbs are one of the natural treatment options that have been proposed. Phyllanthus gomphocarpus Hook. F is a tropical plant that has traditionally been used in Malaysia to treat male infertility. Antioxidant characterization of its root aqueous extraction was performed using ferric reducing antioxidant power (FRAP), 1,1-diphenyl-2-picrylhydrazyl (DPPH), total phenolic content (TPC), and total flavonoid content (TFC). Male rats were administered two different concentrations of the extract orally along with BPA for 21 days, and their sperm was evaluated using Computer-Assisted-Sperm-Analysis (CASA). The results showed that this plant has a high antioxidant capacity, with 78.6 ± 0.65 %, 0.14 ± 0.01 mg/ml, 28.52 ± 0.13 mg GAE/g and 164.73 ± 23.13 mg QE/g, for DPPH, FRAP, TPC and TFC respectively. The ability of this plant to enhance sperm concentration, motility, velocity, progression ratio, elongation, and percentages of normal sperm morphology significantly with p<0.05, appears to be due to its high antioxidant capacity. Furthermore, this plant was found to have sperm-protective effects against the endocrine disruptor BPA. A thorough investigation is required to determine the full mechanism of this plant's beneficial effects on male fertility and human health.
Determinats factors self-management barriers: characteristics, spiritual well-being, and religiosity in type 2 diabetes patients Syabariyah, Sitti; Dewi, Inggriane Puspita; Lestari, Ida Sri; Sajodin, Sajodin; Suwandi, Nur Rohmah
International Journal of Public Health Science (IJPHS) Vol 13, No 4: December 2024
Publisher : Intelektual Pustaka Media Utama

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11591/ijphs.v13i4.24233

Abstract

Holistic nursing needs to evaluate barriers to self-management, insight from characteristics, religiosity, and spiritual well-being to understand and address the multifaceted needs of individuals with chronic conditions, such as diabetes mellitus type 2. This study aimed to identify the determining factors that affect the barriers to self-management and the variables affecting them among Indonesian patients with T2DM. A cross-sectional survey was conducted among 101 patients recruited via purposive sampling from March to May 2023. The research instruments used were the Spiritual Well-Being Scale, Islamic Religiosity Scale, and Summary of Diabetes Self-Care Activities. The potential multicollinearity effects among the predictors of the barriers to self-management were also evaluated using multiple linear stepwise regression and collinearity analysis of variable inflation factors (VIFs). Most of the respondents had moderate spiritual well-being (52.2%) and high Islamic religiosity (60.4%) but also had barriers to self-management (55%). The F value of 5.888 with a probability of 0.004 (<0.05) showed that based on their regression coefficients, spiritual well-being, and Islamic religiosity simultaneously affected the barriers to self-management by 10.7%. The determinants that were found to affect the barriers to self-management were spiritual well-being and religiosity. These results suggest that it is necessary to develop an intervention model to improve the self-management of T2DM with a holistic approach.
Co-Authors Bahari, Ebby Anuar Dasiman, Razif Daud, Kamalru Azman Inggriane Puspita Dewi, Inggriane Puspita Kamarudin, Evana Lestari, Ida Sri Sajodin, Sajodin Syabariyah, Sitti