Article Per Year (5 Year)
p-Index From 2019 - 2024
0.659
P-Index
This Author published in this journals
All Journal MPI (Media Pharmaceutica Indonesiana) THE JOURNAL OF MUHAMMADIYAH MEDICAL LABORATORY TECHNOLOGIST CARADDE: Jurnal Pengabdian Kepada Masyarakat INDONESIAN JOURNAL OF MEDICAL LABORATORY SCIENCE AND TECHNOLOGY
Wulansari, Devyani Diah
Laboratorium Farmasi Klinis Dan Komunitas, Fakultas Farmasi, Universitas Surabaya
Chemistry Education Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Social Sciences

Published : 4 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 4 Documents
Search

 1 
THE EFFECT OF BEETROOT (Beta vulgaris L.) JUICE ON CHOLINESTERASE ACTIVITY IN FARMERS EXPOSED TO ORGANOPHOSPHATE PESTICIDES Devyana Dyah Wulandari; Andreas Putro Ragil Santoso; Devyani Diah Wulansari
JURNAL INDONESIA DARI ILMU LABORATORIUM MEDIS DAN TEKNOLOGI Vol 1 No 2 (2019): Laboratory Analysis Applied to Medical Properties
Publisher : Universitas Nahdlatul Ulama Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/ijmlst.v1i2.1215

Abstract

A decrease in cholinesterase (chE) enzyme activity is an indicator of pesticide poisoning, especially organophosphate pesticides. The chE activity reduction will result in an increase in the amount of acetylcholine and will bound to muscarinic and nicotinic receptors in the central and peripheral nervous system which can lead to the onset of Alzheimer's disease. However, antioxidant products can slow the progression of Alzheimer's disease by protecting neurons from oxidative stress. Red Beetroot (Beta vulgaris L.) contains betalains and phenolic compounds which act as an antioxidants that are capable of preventing such illness. This study aims to prove the concept that antioxidant compounds in red beetroot juice can increase the chE activity in subjects exposed to organophosphate pesticides. This research is an observational study with an experimental approach. This research used 25 farmers who were exposed to organophosphate pesticides as respondents. They were given 500 ml of beetroot juice twice a day for 2 consecutive months. Cholinesterase levels were measured before and after consuming red beet juice. Measurement of cholinesterase levels was carried out using a kinetic photometric test. This method was developed based on recommendations from the German Society of Clinical Chemistry (DGKC). The results showed that the average of chE (U/L) Level Before Treatment was 8.102 and 8.380 after treatment with a p value 0,62. It can be concluded that there was an increase in the level of cholinesterase but it was not statistically significant. This may be caused by a different response to activity of cholinesterase after consuming beetroot juice in each subjects, age difference, smoking habits, and personal protective equipment.
EFEK PAPARAN KRONIS PESTISIDA TERHADAP KADAR ASPARTAT AMINOTRANSFERASE (AST) DAN ALANIN AMINOTRANSFERASE (ALT) PADA SUBYEK PETANI Devyana Dyah Wulandari; Andreas Putro Ragil Santoso; Devyani Diah Wulansari
THE JOURNAL OF MUHAMMADIYAH MEDICAL LABORATORY TECHNOLOGIST Vol 3, No 2 (2020): The Journal of Muhammadiyah Medical Laboratory Technologist
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jmlt.v3i2.5853

Abstract

Farmers in Indonesia are very dependent on pesticides to protect their crops from pests. Farmers are one of the subjects who are susceptible to pesticides and can cause disease due to pesticide accumulation. One of the disease that can arise due to exposure to pesticides is liver damage. This study wanted to determine the effect of pesticide exposure on liver damage seen from AST and ALT enzyme levels using farmer respondents in the Mojokerto area of 25 respondents. From the results of the study it was found that AST levels were influenced by age (P = 0.017), length of work (P = 0.035), and PPE usage (P = 0.044), while age, work period, length of work and usage of PPE did not significantly influence to ALT levels. It can be concluded that age, length of work and use of PPE affect AST levels. Therefore, to prevent the occurrence of pesticide poisoning, farmers must obey the rules on the use of pesticides such as using PPE regularly and always consuming healthy food.
Pengembangan Model Hewan Coba Tikus Diabetes Mellitus Tipe 2 dengan Induksi Diet Tinggi Fruktosa Intragastrik Devyani Diah Wulansari; Devyana Dyah Wulandari
MPI (Media Pharmaceutica Indonesiana) Vol. 2 No. 1 (2018): JUNE
Publisher : Fakultas Farmasi, Universitas Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (545.459 KB) | DOI: 10.24123/mpi.v2i1.1302

Abstract

Pada beberapa tahun terakhir banyak dikembangkan model hewan diabetes mellitus untukmemahami patogenesis, komplikasi, dan pengaruh genetik yang meningkatkan risiko diabetes mellitustipe 2, baik dengan menggunakan bahan kimia maupun dengan modifikasi secara genetik termasuk tikusknockout transgenik, umum, dan knockout spesifik jaringan. Dalam penelitian ini model hewan diabetesmellitus tipe 2 dikembangkan melalui metode pendekatan konsumsi gula pada manusia dengan mengacupada karakteristik kondisi diabetes mellitus tipe 2, penyebab atau mekanisme yang mendasari, serta pertimbangankeuntungan dan kerugian bagi para peneliti dalam penelitian diabetes. Penelitian ini menggunakan32 ekor hewan coba, diadaptasikan selama 14 hari kemudian dibagi dalam 4 kelompok yaitukelompok kontrol, kelompok perlakuan yang diberi larutan fruktosa 2, 5, dan 9 g/kgBB selama 56 hari.Hasil uji komparasi menunjukkan bahwa terdapat perbedaan bermakna antar kelompok (p<0,05) padavariabel dosis fruktosa dan gula darah puasa akhir. Dari penelitian ini dapat disimpulkan bahwa pemberianfruktosa secara intragastrik jangka panjang dapat memicu kenaikan glukosa darah puasa pada tikus.
Peningkatan Keterampilan dan Produktivitas Ekonomis Panti Asuhan Grha Aitam Al Madina Devyani Diah Wulansari; Emma Savitri; Hayuning Purnama Dewi
CARADDE: Jurnal Pengabdian Kepada Masyarakat Vol. 4 No. 2 (2021): Desember
Publisher : Ilin Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31960/caradde.v4i2.1334

Abstract

The purpose of this service program is to improve skills and productivity. economical partner. The method used is through mentoring and training programs by academics from the University of Surabaya related to halal certification, analysis of honey content for quality control and improvement of the packaging process to improve the hygiene of honey products. From the results of this community service program, Partners succeeded in obtaining LPPOM MUI halal certificates for Honey products, analysis of water content, metals, ash, microbial contamination, diastase enzymes, and Hydroxymethyl Furfural (HMF) by SNI 8664-2018, and the honey packaging process through the application of appropriate technology to maintain the hygiene and quality of honey.  
Co-Authors Andreas Putro Ragil Santoso Andreas Putro Ragil Santoso Devyana Dyah Wulandari Emma Savitri Hayuning Purnama Dewi