Journal of Physics and Its Applications
Vol 2, No 1 (2019): November 2019

Calculation of Absorption Dose Value using MIRD Method with Cobalt 57 MIBI for Four Body Organs

Asep Yoyo Wardaya (Department of Physics, Faculty of Science and Mathematics, Diponegoro University)
Wahyu Setia Budi (Department of Physics, Faculty of Science and Mathematics, Diponegoro University)
Ali Khumaeni (Department of Physics, Faculty of Science and Mathematics, Diponegoro University)
Chorirul Anam (Department of Physics, Faculty of Science and Mathematics, Diponegoro University)
Gani Gunawan (Department of Nuclear Medicine, Kariadi General Hospital School of Medicine, Diponegoro University)



Article Info

Publish Date
12 Dec 2019

Abstract

MIRD has developed methods, assumptions, models, and mathematical formulae for estimating internal radiation doses from the injected radiopharmaceuticals into the body. This study aims to determine the radiopharmaceutical distribution of Cobalt 57 MIBI in patients identified as having breast cancer by using an oncology examination with MIRD method on 4 patient's organs with some time variations. The four organs of the patient's body are the heart, thyroid, kidney, and liver. The MIRD method developed to calculate the absorption dose of each organ is the product of the cumulative activity and the S factor of each organ studied. The results showed that the highest uptake dose in these patients was in the thyroid and kidney organs, and then followed by the heart and liver. These results indicate that the thyroid and kidney organs are the most vulnerable organs by the method of injecting radiopharmaceutical doses into the body of breast cancer patients.

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Journal Info

Abbrev

jpa

Publisher

Subject

Astronomy Earth & Planetary Sciences Materials Science & Nanotechnology Physics

Description

Journal of Physics and Its Applications (JPA) (e-ISSN: 2622-5956) is open access, International peer-reviewed journal that publishes high-novelty and original research papers and review papers in the field of physics including Radiation Physics, Materials, Geophysics, Theoretical Physics, ...