Journal of Tropical Pharmacy and Chemistry
Vol. 4 No. 5 (2019): Journal of Tropical Pharmacy and Chemistry

Bacterial Symbionts of Soft Coral Lobophytum Sp. From Panjang Island, Jepara, Indonesia With Antimicrobial MDR TB Potency

Yuvianti Dwi Franyoto (STIFAR “Yayasan Pharmasi Semarang” Semarang, Indonesia)
Ahmad Fuad Masduqi (STIFAR “Yayasan Pharmasi Semarang” Semarang, Indonesia)
Sakti Muchlisin (Tropical Marine Biotechnology Laboratory, Diponegoro University, Semarang, Indonesia)
Prasetyo Abi Widyananto (Tropical Marine Biotechnology Laboratory, Diponegoro University, Semarang, Indonesia)
Sulistiyani Sulistiyani (Faculty of Public Health, Diponegoro University, Semarang, Indonesia)
Diah Permata Wijayanti (Faculty of Fisheries and Marine Science, Diponegoro University,Semarang, Indonesia)
Lia Kusmita (STIFAR "Yayasan Pharmasi Semarang", Indonesia)

Article Info

Publish Date
30 Jun 2019

Abstract

Tubercolusis is a disease that attacks the lungs. The disease is caused by the bacterium mycobacterium tubercolusis. The bacteria mycobacterium tubercolusis can be killed by antibiotics. However, continuous use of antibiotics can cause bacterial resistance. So we need to find new drugs that can prevent multi-drug resistant tuberculosis. This study aims to determine the antibacterial activity of MDR TB from soft coral symbiont bacteria Lobophytum sp. There were 6 bacterial isolates obtained from soft coral Lobophytum sp. One isolate from Lobophytum-associated bacteria were successfully screened for antimycobacterial against MDR TB bacteria. PLO2 was found to inhibit the growth of MDR TB (MDR TB strain SIRE and R). Based on the results of identification with PCR, soft coral symbionts of PLO2 was closely related to Virgibacillus marismortui with homology of 99%.

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Journal Info
Journal of Tropical Pharmacy and Chemistry
Website

Abbrev

jtpc

Publisher

Universitas Mulawarman

Subject

Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Medicine & Pharmacology Public Health

Description

Journal of Tropical Pharmacy and Chemistry is a Biannual, international, open access (Indexed in DOAJ, Crossref, SINTA, PKP Index, BASE, Moraref, Google Scholar), journal dedicated to various disciplines of pharmaceutical and allied sciences. Journal of Tropical Pharmacy and Chemistry (ISSN-p: ...