Blood Bank's challenge during the COVID-19 era is securing and protecting blood supplies even though countries are taking precautionary measures with social distancing to prevent or reduce the number of infections caused by COVID-19. This study aimed to compare blood availability before and during the COVID-19 pandemic at the blood bank of Dr. Wahidin Sudirohusodo Hospital. A Descriptive-analytic study with an observational approach using the Shapiro-Wilk test to determine the normality of the sample and the paired T-test. Sample data was taken between March-August 2019 and March-August 2020. A significant difference was found in blood demand (p-value=0.004), amount of blood transfusion(p-value=0.006), stock and reference report (p-value=0.005), blood service report (p-value=0.005), cito waiting time (p-value=0.002) and regular waiting time (p-value=0.016). There was no significant difference in blood indicator Packed Red Cell (PRC) (p-value=0.119). The Large-Scale Social Restriction Policy (PSBB) and reduction of elective surgery in hospitals affect the fulfillment of Blood Bank and faster attendance time of blood during the pandemic. The decrease in a number of blood demands during the COVID-19 pandemic affected the number of blood transfusions, blood service reports, stocks, referrals, and cito and regular waiting time services.
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