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Identification of Risk Factors Characteristics of Transfusion Reaction Eko Putri Rahajeng; Raehana Samad; Rachmawati Muhiddin
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol 26, No 3 (2020)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v26i3.1413

Blood transfusion is an important part of health care. A blood transfusion can be carried out after careful consideration of its risks and benefits. One of the important considerations for blood transfusion is adverse transfusion reaction. Several risk factors for a transfusion reaction are age, gender, repeated transfusion, disease diagnosis, type of blood component, and blood incompatibility. This research is a descriptive study performed at Blood Bank Dr. Wahidin Sudirohusodo Hospital, Makassar, from January to December 2017. The subjects were all patients reported to have an acute transfusion, totaling 104 subjects. The descriptive method was carried out by the calculation of frequency distribution. From January to December 2017, 104 patients with transfusion reactions were obtained, predominantly were male (53.8%), with the lowest age range of ≥ 60 years (27.9%), packed red cell as the most found blood components (82.4%), a history of previous transfusion reactions (72.1%), and a diagnosis of malignancy (53.9%). The history of repeated transfusions is the most common risk factor compared to age, gender, blood component, and patient diagnosis.

Analysis of Blood Availability During the COVID-19 Pandemic Period in Blood Bank Dr. Wahidin Sudirohusodo Hospital Antariksa Putra; Raehana Samad; Sri Julyani; Rachmawati Adiputri Muhiddin
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol 28, No 1 (2021)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v28i1.1752

Blood Bank's challenge during the COVID-19 era is securing and protecting blood supplies even though countries aretaking precautionary measures with social distancing to prevent or reduce the number of infections caused by COVID-19.This study aimed to compare blood availability before and during the COVID-19 pandemic at the blood bank of Dr. WahidinSudirohusodo Hospital. A Descriptive-analytic study with an observational approach using the Shapiro-Wilk test todetermine the normality of the sample and the paired T-test. Sample data was taken between March-August 2019 andMarch-August 2020. A significant difference was found in blood demand (p-value=0.004), amount of blood transfusion(p-value=0.006), stock and reference report (p-value=0.005), blood service report (p-value=0.005), cito waiting time(p-value=0.002) and regular waiting time (p-value=0.016). There was no significant difference in blood indicator Packed RedCell (PRC) (p-value=0.119). The Large-Scale Social Restriction Policy (PSBB) and reduction of elective surgery in hospitalsaffect the fulfillment of Blood Bank and faster attendance time of blood during the pandemic. The decrease in a number ofblood demands during the COVID-19 pandemic affected the number of blood transfusions, blood service reports, stocks,referrals, and cito and regular waiting time services.

WAKTU PENYIMPANAN TROMBOSIT TERKAIT JUMLAH DI KONSENTRAT TROMBOSIT Raehana Samad; Agus Alim Abdullah; Kusriny A.P.; Mansyur Arif
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol 20, No 3 (2014)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v20i3.481

The transfusion of thrombocyte concentrate is one of the important medical approaches to make the platelet count raised in patients with thrombocytopenia. The TC could change during the storage process, so the in vitro storaging should be considered to minimalize the alterations on the platelet count. The study was aimed to know the impact of storage time to maintain the platelet count stability in TC of transfusion blood by evaluating it. A study with Time Series design was performed in 30 samples of TC of transfusion blood collected from 30 blood donors. The samples was collected from the bag tube of TC and the test is performed as soon as possible by using haematological analyzer (Sysmex KX-21) with an impedance method, the rest of the samples was stored in an agitator on 22±2°C to perform a repeated count on day 5th and 7th. The collected data was analyzed with “Paired T Test”. The results of this study showed that the platelet count in TC of transfusion blood was decreased in the fifth day compared to the first day, but the decreased matter is insignificant, statistically (p=0.13). While after seventh (7) day, the platelet count is decreased significantly (p=0.00). The researchers concluded that the storage of TC for seven (7) days could not maintain the stability of the platelet count of the transfusion blood. There fore is suggested, a further study to evaluate the impact of storage time on platelets viability. So the quality of platelets in TC of transfusion blood can be evaluated.

Platelet Count and Platelet Index as Prognosis Markers in Adult Septic Patients Steven Tiro; Raehana Samad; Uleng Bahrun
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol 26, No 1 (2019)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v26i1.1357

Sepsis is a major health problem with recent increase of incidence. One of life-threatening complications of sepsis isDisseminated Intravascular Coagulation (DIC). DIC in sepsis can trigger an increase of platelet destruction which can beassessed by platelet count and platelet index. Hence, this research aimed to analyze the correlation of platelet count andplatelet index to the prognosis of adult septic patients. This research was then performed with a retrospective longitudinalstudy design. This research used the medical record data of adult septic patients at the Dr. Wahidin Sudirohusodo GeneralHospital in Makassar. The data of platelet count and platelet index were collected from routine blood of the patients for thefirst time they were diagnosed with sepsis. In total, this research was performed on 100 adult sepstic patients. Fifty of thosepatients had a good prognosis (cured), while the other fifty patients had a poor prognosis (died). Statistical results showedthat the platelet count in the adult sepsis patients with a poor prognosis was significantly lower than those in patients with agood prognosis with median/minimum-maximum of 157,000/12,000-626,000 and 329,000/96,000-801,000, respectively(p=0.00). It was also known that there was no significant difference of MPV values between patients with poor prognosis andpatients with good prognosis with Mean±SD of 9.54±1.44 and 10.08±2.09, respectively (p=0.138). Unlike MPV values, PDWvalues in patients with poor prognosis were significantly higher than those in patients with good prognosis with Mean±SDof 16.7±6.26 and 11.25±2.13, respectively (p=0.00). Thus, it can be concluded that there was an inverse correlation betweenplatelet count and PDW value (r = -0.58). PDW value, as a result, could be used as a prognosis marker for adult septicpatients. However, it was recommended to perform further research as a prospective study by removing the possibility ofbias.

Platelet Count and Platelet Index as Prognosis Markers in Adult Septic Patients Steven Tiro; Raehana Samad; Uleng Bahrun
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol. 26 No. 1 (2019)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v26i1.1357

Sepsis is a major health problem with recent increase of incidence. One of life-threatening complications of sepsis is Disseminated Intravascular Coagulation (DIC). DIC in sepsis can trigger an increase of platelet destruction which can be assessed by platelet count and platelet index. Hence, this research aimed to analyze the correlation of platelet count and platelet index to the prognosis of adult septic patients. This research was then performed with a retrospective longitudinal study design. This research used the medical record data of adult septic patients at the Dr. Wahidin Sudirohusodo GeneralHospital in Makassar. The data of platelet count and platelet index were collected from routine blood of the patients for the first time they were diagnosed with sepsis. In total, this research was performed on 100 adult sepstic patients. Fifty of those patients had a good prognosis (cured), while the other fifty patients had a poor prognosis (died). Statistical results showed that the platelet count in the adult sepsis patients with a poor prognosis was significantly lower than those in patients with a good prognosis with median/minimum-maximum of 157,000/12,000-626,000 and 329,000/96,000-801,000, respectively (p=0.00). It was also known that there was no significant difference of MPV values between patients with poor prognosis and patients with good prognosis with Mean±SD of 9.54±1.44 and 10.08±2.09, respectively (p=0.138). Unlike MPV values, PDW values in patients with poor prognosis were significantly higher than those in patients with good prognosis with Mean±SD of 16.7±6.26 and 11.25±2.13, respectively (p=0.00). Thus, it can be concluded that there was an inverse correlation between platelet count and PDW value (r = -0.58). PDW value, as a result, could be used as a prognosis marker for adult septic patients. However, it was recommended to perform further research as a prospective study by removing the possibility of bias.

Identification of Risk Factors Characteristics of Transfusion Reaction Eko Putri Rahajeng; Raehana Samad; Rachmawati Muhiddin
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol. 26 No. 3 (2020)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v26i3.1413

Blood transfusion is an important part of health care. A blood transfusion can be carried out after careful consideration of its risks and benefits. One of the important considerations for blood transfusion is adverse transfusion reaction. Several risk factors for a transfusion reaction are age, gender, repeated transfusion, disease diagnosis, type of blood component, and blood incompatibility. This research is a descriptive study performed at Blood Bank Dr. Wahidin Sudirohusodo Hospital, Makassar, from January to December 2017. The subjects were all patients reported to have an acute transfusion, totaling 104 subjects. The descriptive method was carried out by the calculation of frequency distribution. From January to December 2017, 104 patients with transfusion reactions were obtained, predominantly were male (53.8%), with the lowest age range of â‰¥ 60 years (27.9%), packed red cell as the most found blood components (82.4%), a history of previous transfusion reactions (72.1%), and a diagnosis of malignancy (53.9%). The history of repeated transfusions is the most common risk factor compared to age, gender, blood component, and patient diagnosis.

Analysis of Blood Availability During the COVID-19 Pandemic Period in Blood Bank Dr. Wahidin Sudirohusodo Hospital Antariksa Putra; Raehana Samad; Sri Julyani; Rachmawati Adiputri Muhiddin
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol. 28 No. 1 (2021)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v28i1.1752

Blood Bank's challenge during the COVID-19 era is securing and protecting blood supplies even though countries are taking precautionary measures with social distancing to prevent or reduce the number of infections caused by COVID-19. This study aimed to compare blood availability before and during the COVID-19 pandemic at the blood bank of Dr. Wahidin Sudirohusodo Hospital. A Descriptive-analytic study with an observational approach using the Shapiro-Wilk test to determine the normality of the sample and the paired T-test. Sample data was taken between March-August 2019 and March-August 2020. A significant difference was found in blood demand (p-value=0.004), amount of blood transfusion(p-value=0.006), stock and reference report (p-value=0.005), blood service report (p-value=0.005), cito waiting time (p-value=0.002) and regular waiting time (p-value=0.016). There was no significant difference in blood indicator Packed Red Cell (PRC) (p-value=0.119). The Large-Scale Social Restriction Policy (PSBB) and reduction of elective surgery in hospitals affect the fulfillment of Blood Bank and faster attendance time of blood during the pandemic. The decrease in a number of blood demands during the COVID-19 pandemic affected the number of blood transfusions, blood service reports, stocks, referrals, and cito and regular waiting time services.

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