Medical Sains : Jurnal Ilmiah Kefarmasian
Vol 8 No 2 (2023)

PHYSICAL EVALUATION OF CURCUMA RHIZOME EXTRACT (Curcuma xanthorrhiza) FORMULATION IN ANTI ACNE LOOSE POWDER

Marini Marini (STIKES Muhammadiyah Kuningan)
Haty Latifah Priatni (STIKES Muhammadiyah Kuningan)
Azmi Darotulmutmainnah (STIKES Muhammadiyah Kuningan)
Dea Safitri (STIKES Muhammadiyah Kuningan)



Article Info

Publish Date
26 Jun 2023

Abstract

When Staphylococcus aureus and Staphylococcus epidermis are isolated from acne-proneskin, the essential oil and curcuminoids in curcumin (Curcuma zanthorrhiza Roxb) exhibitantibacterial activity against blemished skin. The purpose of this study was to create an antiacne loose powder using Curcuma rhizome extract and to determine which formulationsmeet the best test requirements. Extraction was carried out using the maceration methodwith 96% ethanol solvent. The powder formulation consisted of alba bolus, magnesiumcarbonate, magnesium stearate, zinc oxide, oleum rosae, and talc, developed withtemulawak rhizome extract at concentrations of F0 (0%), F1 (8%), F2 (10%), and F3 (12%).The evaluation of the powder preparation was organoleptic, humidity, powder flow rate,specific gravity, and pH.. The results indicated that the F1 formulation's humidity test resultsof less than 10%, the speed of the powder flow evaluation test results was 15.6%, the angleof repose test result was 26.6°, and the measurement of pH showed that the result of 6fulfilled the requirements. Based on a physical test of the anti-acne loose powder, theCurcuma rhizome extract in the FI formulation with an 8% concentration produced optimalresults. Keywords: anti acne, physical evaluation, loose powder, curcuma

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Journal Info

Abbrev

iojs

Publisher

Subject

Medicine & Pharmacology

Description

The Medical Sains journal is a scientific publication media published by the Muhammadiyah Cirebon College of Pharmacy which is published 4 (four) times in 1 (one) year, namely January-March, April-June, July-September and October-December. The journal contains research in the field of pharmacy ...