Jurnal Farmasi Higea
Vol 6, No 2 (2014)

Pengaruh Pemberian Ekstrak Daun Gaharu (Aquilaria Malaccensis Lam.) Terhadap Aterosklerosis Pada Burung Puyuh Jantan (Coturnix-Coturnix Japonica)

Suhatri Suhatri (Fakultas Farmasi Universitas Andalas Padang)
Dian Zaini Putra (Sekolah Tinggi Ilmu Farmasi (STIFARM) Padang)
Elisma Elisma (Sekolah Tinggi Ilmu Farmasi (STIFARM) Padang)



Article Info

Publish Date
22 Feb 2017

Abstract

Study about the influence of agarwood leave’s extract (Aquilaria malaccensis Lam.) on the formation of atherosclerosis in male quail (coturnic-coturnix japonica) induced high fat feeding and prophylthiourasil. Animal experiments were grouped into 5 consisting of Group I as a negative control only given food strander, group II as a positive control and PTU given MLT groups III, IV, V given leaf extract of aloes with a dose of 100 mg / kg BW, 300 mg / kg BW, 900 mg / kg BW and, along with the MLT and PTU the extract was given orally once a day for 60 day. The doses used were 100, 300, 900 mg/kg body weight respectively. Control groups was given food standar. Result showed that the administration of the agarwood leaf extract could prevent formation of atherosclerosis in male quail significantly (P <  0.05). The optimal effect showed doses 100 mg/kg BW.

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