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INDONESIA
BIOEDUSCIENCE
Published by Universitas Muhammadiyah Prof. Dr. Hamka
ISSN : 2614154X     EISSN : 26141558     DOI : -
Core Subject : Science, Education, Agriculture,
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Education
BIOEDUSCIENCE is an open access journal that publishes research in the field of Biology and Biosain Education such as: Applied and implemented in education and learning, Botany, Zoology, Microbiology, Ecology, Biotechnology, Molecular Biology, Genetics, Bioinformatics, Cell and Developmental Biology, Biodiversity and Bioconservation. BIOEDUSCIENCE is published by Biology Education Study Program, Universitas Muhammadiyah Prof. Dr. Hamka, Indonesia regularly in June and December. ISSN : 2614-1558; P-ISSN : 2614-154X.
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Articles 39 Documents
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Search results for , issue "Vol 6 No 1 (2022): BIOEDUSCIENCE" : 39 Documents clear
Extraction and Identification Potent Antibacterial Bioactive Compound of Streptomyces sp. MB 106 from Euphorbia sp. Rhizosphere Dian Rachma Wijayanti; Almatin Puspa Dewi
BIOEDUSCIENCE Vol 6 No 1 (2022): BIOEDUSCIENCE
Publisher : Universitas Muhammadiyah Prof. Dr. Hamka

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/j.bes/617898

Abstract

Background: Actinomycetes are groups of bacteria that play an important role in pharmacy and medicine in their ability to produce secondary metabolites in the form of bioactive compounds with various chemical structures and biological activities. The genus Streptomyces produces more than 70% of all described actinomycetes natural products. In particular, antibiotics represent the largest group. Through mutations, bacteria may survive chemotherapy. Thus its infection is hard to eradicate. Therefore the search for new potent bioactive compounds is important Methods: Isolate preparation, Production, and extraction bioactive compound, Crude extract antibacterial test, Identification of bioactive compound Results: There are antibacterial activities per 100 µl crude extract. Inhibition zone range from 11.5 to 13 mm. Various bioactive compounds detected in n-Butanol extract, There are nine bioactive compounds detected from Streptomyces sp. MB 106 crude extract. The highest was Naphthalene (43.89 %). The lowest was 3-Imino-3h,5h- [1,2,4] Thiadiazolo [3,4-1] Isoindole (1.70 %). Six compounds were reported to have antimicrobial activities butane, 1,1-dibutoxy, naphthalene, nonadecane, docosane, heneicosane, and eicosane Conclusions: Crude extract showed an average of 12 mm inhibition zone against Escherichia coli ATCC 8739. There are nine bioactive compounds from Streptomyces sp. MB 106. Six of them are promising drugs candidate. Further studies on these compounds are essential for future drugs candidate.
Peningkatan Pemahaman Konsep Keanekaragaman Hayati melalui Model Pembelajaran Biologi Berbasis Lingkungan Nursidin Nursidin; Rusman Rusman; Laksmi Dewi
BIOEDUSCIENCE Vol 6 No 1 (2022): BIOEDUSCIENCE
Publisher : Universitas Muhammadiyah Prof. Dr. Hamka

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/j.bes/618016

Abstract

Background: Indonesia has abundant biodiversity. The concept of biodiversity was chosen because there are still places that must be known that students can use as learning resources. The learning innovation carried out is the application of environment-based knowledge to improve students' understanding of the concept of biodiversity. Method: This study used a pretest-posttest group design, 105 students of class X SMA Negeri Asera. The research sample consisted of 2 classes, namely the experimental and control classes. The experimental class uses environment-based learning and the control class uses conventional learning. The data was obtained through a test of understanding the concept of biodiversity and interviews. Data analysis was carried out by descriptive analysis and inferential statistics. Hypothesis testing through t-test using SPSS 20.0 program. Result: There is a difference in values between the experimental and control classes, where the experimental class values are higher than the control class values with that = 10,899. Conclusion: The application of this environment-based learning can affect student learning outcomes of SMA Negeri Asera.
Pemanfaatan Pewarna Alami Kain Tenun Futus Sebagai Alternatif Pewarna Preparat Jaringan Tumbuhan Yolanda Getrudis Naisumu; Emilia Juliyanti Bria; Welli Herlince Kasse
BIOEDUSCIENCE Vol 6 No 1 (2022): BIOEDUSCIENCE
Publisher : Universitas Muhammadiyah Prof. Dr. Hamka

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/j.bes/618079

Abstract

Background: Natural plant dyes can replace synthetic dyes to reduce the negative effects caused. This study aims to determine the types of color-producing plants, the process of using natural dyes as dyes for plant tissue preparations and the percentage of quality and feasibility of plant tissue preparations. Methods: experiments were carried out in the application of natural plant dyes on plant tissue preparations. Data analysis was carried out to calculate the percentage of quality and feasibility of the preparations. Results: there were eight plant species from four families namely Fabaceae, Zingiberaceae, Maliaceae, and Lamiaceae. The process of processing plant parts into natural dyes is by soaking, boiling, pounding, grated and applied to preparations of corn and spinach plants. The use of natural dyes on corn and spinach preparations with a percentage of preparation quality ranging from 33.33% - 75.00% and said to be poor to good, while the percentage of feasibility of preparations ranged from 67.08% - 87.50% and was said to be feasible to very suitable for use in the observation of plant cells and tissues. Conclusions: Natural dyes from futus fabrics can replace synthetic dyes in dyeing plant tissue preparations.
Anti-PD-L1 Therapy as a Solution for Non-Melanoma Skin Cancer Basal Cell Carcinoma Rahul Simon Situmeang; Gim Mi Kyong; Rosiva Betaria Purba; Wahyu Irawati
BIOEDUSCIENCE Vol 6 No 1 (2022): BIOEDUSCIENCE
Publisher : Universitas Muhammadiyah Prof. Dr. Hamka

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/j.bes/618095

Abstract

Skin cancer is a disease that can cause the loss of the ability to regenerate and protect the skin normally. The types of skin cancer that are known are melanoma and non-melanoma skin cancer. Non-melanoma Basal cell carcinoma is a malignant neoplasm originating from non-keratinizing cells in the basal layer of the skin's epidermis. The treatment itself is carried out through the application of immunotherapy, namely the use of drug therapy Programmed Death Ligand 1 (PD-L1). This study aims to see the effectiveness of PD-L1 Therapy as a treatment for basal cell carcinoma. The focus of the study of the article is the integument system, skin cancer, non-melanoma basal cell carcinoma, and the effect of anti-PD-L1 use. The research method used is a literature review from various sources. Skin cancer Basal cell carcinoma attacks the basal cells of the epidermis, causing disruption. Attacks slowly, but when ignored will spread wider and more severe. Through PD-L1 therapy by binding to PD-1 receptors on immune cells, it causes the activation of T lymphocytes as anti-cancer cells in the body that suppress growth while actively controlling tumor cells. Through the use of PD-L1 therapy in treating cancer that attacks basal cells, it will suppress growth, destroy and shrink cancer cells, and increase the body's immunity against cancer cells.
Gastropoda Diversity in Polyculture Agricultural Ecosystem of Nansean Village, Insana District, North Central Timor Regency- East Nusa Tenggara Province (NTT) Blasius Atini; Aloysius Rusae
BIOEDUSCIENCE Vol 6 No 1 (2022): BIOEDUSCIENCE
Publisher : Universitas Muhammadiyah Prof. Dr. Hamka

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/j.bes/618539

Abstract

Background: The research was carried out in the polyculture area of Nansean Village, North Central Timor Regency. This study aims to determine the diversity of Gastropoda species and also to determine the influence of environmental factors on the Gastropoda life in the polyculture agricultural ecosystem of Nansean Village. Methods: The method used in this research is the quadratic method by placing plots along the transect line. The data analysis technique for Gastropoda diversity was using the Shannon-Winner diversity formula. Results: From the results of the study, it was found that 6 types of Gastropoda namely Achatina fulica with a diversity index (H') of (3.51) were classified as high. Laevicaulis alte Bowd with a diversity index (H') of (1,15) was classified as moderate. Felicaulis sp with a diversity index (H') of (1,25) was classified as moderate, Bradybaena similaris Frussac with a diversity index (H') of (1,26) was classified as moderate. Achatina variegata Bowd with diversity index (H') of (0.92) is low. Doraceras leave sp with a diversity index (H') of (0.87) is low. Species diversity shows the pattern of adaptation to ecosystem conditions is quite good, and vice versa if the type of Gastropoda is low. Conclusions: the environment has a role in diversity variations in Nansean Village, Insana District, and North Central Timor Regency.
Konsentrasi Logam Berat Cd, Hg, Pb pada Produk Pangan Olahan Berbahan Dasar Pterygoplichthys pardalis (Castelnau, 1855) asal Sungai Ciliwung Wilayah Jakarta Dewi Elfidasari; Haninah Haninah; Handhini Dwi Putri; Irawan Sugoro
BIOEDUSCIENCE Vol 6 No 1 (2022): BIOEDUSCIENCE
Publisher : Universitas Muhammadiyah Prof. Dr. Hamka

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/j.bes/618708

Abstract

Backgrounds: Heavy metal that pollutes the river area affects living organisms which reside in it. Contamination of heavy metal in Ciliwung River leads to the presence of heavy metal elements (Cd, Hg, and Pb) inside the body of the plecos (Pterygoplichtys Pardalis) which inhabits that area. Hence, the utilization of plecos flesh and bones as a raw material in processed food products (e.g. shredded fish, shumai, and fish flour) might be harmful for human. Accumulated load of heavy metal in human's body would likely trigger health problems. Insufficient data on heavy metal concentration in Ciliwung River plecos-based food products underlies this research, with the aim to calculate the concentration of heavy metal Cd, Hg, and Pb on the previously mentioned plecos-based shredded fish, shumai, and flour. Methods: Heavy metal Cd, Hg, and Pb concentration analysis using X-Ray Fluoresence (XRF) methods conducted on PAIR Batan. Results: Value of Cd on shredded fish <0.5 mg/kg, shumai 0,7 mg/kg, head+tailbone and body skeleton flour <0.3 mg/kg. Value of Hg on shredded fish and shumai <0.7 mg/kg, head+tailbone flour 0.3 mg/kg, body skeleton flour 0.4 mg/kg. Value of Pb on shredded fish 1.3 mg/kg, shumai 0.8 mg/kg, head+tailbone flour 2.3 mg/kg, body skeleton flour 1.6 mg/kg. Conclusions: Heavy metal concentration on Ciliwung River plecos-based processed food products (shredded fish, shumai, and flour) has exceed maximum limit of Cd, Hg, and Pb determined by SNI, BPOM, and FAO.
Investasi Hama Penggerek Pucuk Kelapa (Oryctes rhinoceros) Pada Plasma Nutfah Agave Parnidi Parnidi; Dwi Adi Sunarto; Marjani Marjani
BIOEDUSCIENCE Vol 6 No 1 (2022): BIOEDUSCIENCE
Publisher : Universitas Muhammadiyah Prof. Dr. Hamka

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/j.bes/616282

Abstract

Background: Agave is known as one of the natural fiber-producing plants that have many benefits. Agave plants can grow well on dry land, however, many organisms can damage agave crops in the field. One of the agave plant is Shoot Borers Beetle Pest of Coconut (Oryctes rhinoceros L). The purpose of this research is to get information about variation damage of agave germ plasma to Shoot Borers Beetle Pest of Coconut (Oryctes rhinoceros L). Methods: The research was conducted at the Agave balittas collection in the Experimental Garden Balittas Karangploso. Observation of shoot borers beetle pest of coconut (Oryctes rhinoceros L.) was carried out on 6 plants. Observations were made by calculating the number of holes that were found on the leaves. Results: The results showed that the investment of Shoot Borers Beetle Pest of Coconut (Oryctes rhinoceros L) causing damage to agave germplasm varies. The average percentage of damage to Agave angustifolia and Agave cantala in 2017 due to the investment in Shoot Borers Beetle Pest of Coconut (Oryctes rhinoceros L) is range from 66.7 to 100%. The average damage caused by Shoot Borers Beetle Pest of Coconut (Oryctes rhinoceros L) investment in Agave sisalana ranges from 0 to 16.7%. Conclusions: The investment of shoot borers beetle pest of coconut in agave plants has a big impact on decreasing crop production and fiber quality.
Diversity and Potential of Flowering Plants in Timau Mutis Nature Reserve, Tasinifu Village Ite Morina Yostianti Tnunay; Florian Mayesti Prima R. Makin; Welsiliana Welsiliana
BIOEDUSCIENCE Vol 6 No 1 (2022): BIOEDUSCIENCE
Publisher : Universitas Muhammadiyah Prof. Dr. Hamka

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/j.bes/616923

Abstract

Background: The mountain ecosystem in Mutis Timau Nature Reserve, Oelmuke Village, has a high diversity of flowering plants but has not been recorded. Inventaritation of the flowering plant provides reference information for area conservation. This study aims to inventory the types and uses of flowering plants by the community and other potential benefits in the Mutis Timau Nature Reserve, Oelmuke Hamlet, East Nusa Tenggara. Method: This research was conducted in August 2019 in Oelmuke Village, East Nusa Tenggara. The plant collection was conducted using an experimental method along the Oelmuke Village area. The information on the use of flowering plants by the community using the interview method and information about other potential uses using the literature review method. Result: The flowering plants inventoried from Oelmuke Village is 31 species from 15 families that have been used as food, animal feed, building materials, medicinal materials, ornamental plants, hedge plants, firewood, and cigarette raw materials, and textile materials. Other potential uses are as an accumulator of Pb waste and dye for woven fabrics. Conclusions: The 31 species of plants that have been inventoried have been used by the community as food, animal feed, building materials, medicinal materials, ornamental plants, hedges, firewood, cigarette raw materials, and textile materials and other potential uses are accumulator Pb waste and dyes for woven fabrics
Guided Inquiry-Based Electronic Module Development on Circulation System Ma-Terial to Improve Student Learning Outcomes Madiany Erika Purnama; Saleh Hidayat; Rusdy A. Siroj
BIOEDUSCIENCE Vol 6 No 1 (2022): BIOEDUSCIENCE
Publisher : Universitas Muhammadiyah Prof. Dr. Hamka

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/j.bes/617089

Abstract

Background: Industrial era 4.0 has an impact on the world of education. This affects students, where students can understand subject matter such as biology, which contains abstract concepts such as circulation system material. The teaching materials developed in this study are expected to improve student learning outcomes by integrating guided inquiry learning models. This study aimed to determine the validity, practicality, and effectiveness of guided inquiry-based electronic modules. Method: 4D model development research. Data collection by interview and questionnaire sheet. Result: The module validation of the language validator is 83%, the material is 81%, the media 81% has a good category, while the learning device validator is 96%, the learning validator is 98%, and 94% has a very good category. Practicality is taken from student responses which are divided into three stages: 81% preliminary trial, 89% quantitative trial, and 92% final trial showing a positive response. The effectiveness of this guided inquiry-based electronic module can improve student learning outcomes seen from the N-Gain score results. The control class is 0.38 with medium criteria, and the experimental class is 0.73 with high criteria. While the psychometric results of students who studied using guided inquiry-based electronic modules for three meetings, namely the first meeting 77% (good), the second meeting 91% (very good), and the third meeting 88% (very good). Conclusion: Guided inquiry-based electronic module on circulation system material has a potential effect on improving student learning outcomes
Pengembangan Booklet Kelainan Sistem Peredaran Darah Disertai Pengayaan Uji Aktivitas Antidislipidemia Ekstrak Daun Salam Nur Dwi Handarsiputri; Titin Titin; Wolly Candramila
BIOEDUSCIENCE Vol 6 No 1 (2022): BIOEDUSCIENCE
Publisher : Universitas Muhammadiyah Prof. Dr. Hamka

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/j.bes/617418

Abstract

Background: Media booklets are media used in the learning process that have advantages in supportive conditions. The booklet contains a summary of the material that is equipped with pictures and colors so that it is interesting. This study aims to develop a booklet with enriched information about the antidyslipidemic activity test of bay leaf extract (Syzygium polianthum (Wight) Walp.) as a learning medium in the Sub Material of Circulatory System Abnormalities for second grade of highschool. Methods: This development research uses the type of research and development (R&D). The development stages include potentials and problems, data collection, product design, design validation, design revision, and product. The media booklet was validated by 5 validators in terms of format, content, and language, all of which covered 9 criteria. Results: Validation obtained Content Validity Ratio (CVR) and Content Validity Index (CVI) values "‹"‹of 1 which meet the minimum criteria for content validity. Conclusion: Thus, the booklet enriched with the results of the antidyslipidemic activity test of bay leaf extract (Syzygium polianthum (Wight) Walp.) was declared content valid as a learning medium in the Circulatory System Abnormalities Submaterial.

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