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INDONESIA
Jurnal Respirologi Indonesia
ISSN : 08537704     EISSN : 26203162     DOI : -
Core Subject : Health,
Jurnal Respirologi Indonesia (JRI) is an online and printed scientific publication of the Indonesian Society of Respirology (ISR). The journal is published thrice-monthly within a year (January, April, July and October). The journal is focused to present original article, article review, and case report in pulmonary and critical care medicine.
Arjuna Subject : -
Articles 264 Documents
Case Report: Pneumonia Like Mass with Spontaneous Resolution Aisyah Ayu Safitri; Muhammad Fahmi Alatas
Jurnal Respirologi Indonesia Vol 43, No 3 (2023)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/jri.v43i3.205

Abstract

Background: Pneumonia can easily mimic malignancies. Pulmonary nodule finding raise concern for lung cancer. A single lung opacity less than 3 centimetres in diameter is referred to as a solitary pulmonary nodule (SPN). These nodules sometimes incidentally discovered during routine computed tomography (CT) scan of the chest in relatively asymptomatic patients. We present unusual case of pneumonia like mass with spontaneous resolution.Case: Woman, 38-year-old, with solitary pulmonary nodule which was found accidentally in the left lung upper lobe, without any respiratory symptoms in June 2021. In August 2021, a chest CT scan was done for evaluating and the solitary nodule of the left lung upper lobe had resolved spontaneously without any treatment. The patient was prepared for diagnostic bronchoscopy at Persahabatan Hospital with the findings of normal bronchi and the branches. A bronchial washing was performed on the left B1+2 segment and cytology, fungal, microorganism and molecular tuberculosis examination were performed.Discussion: Pulmonary solitary nodule in left lung upper lobe in the beginning and spontaneous resolution after 2 months evaluation without any specific treatment, consider period of pneumonia. Whenever a patient is found to have an SPN, it is essential to determine the patient’s risk for malignancy. It is important to consider any pulmonary nodule to be malignant or not, and how it presents on CT Imaging.Conclusion: Pulmonary nodule may be found during pneumonia and may resolve spontaneously. The possibility of malignancy must still be considered. Awareness of condition from the history is important to help reassure patient about the disease even before diagnostic procedure was made.
Chest Radiography and CT scan as Predictor Factors for Long COVID Reny Luhur Setyani; Srie Retno Endah; Ana Madjawati; Muhammad Hafiz; Farsida Farsida; Rahma Ayu Larasati; Turwuri Handayani; Khatarina Setyawati
Jurnal Respirologi Indonesia Vol 43, No 4 (2023)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/jri.v43i4.539

Abstract

Background: Long COVID presents a significant challenge in the management of COVID-19 patients, necessitating risk stratification and early intervention to mitigate its impact.Objective: This retrospective cohort study aimed to establish a predictive link between initial clinical assessments and imaging findings upon COVID-19 diagnosis and the subsequent development of long COVID symptoms at 6-8 weeks post-treatment.Methods: The study analyzed chest radiography images utilizing the Brixia Score and chest CT scans employing the Severity Score at the time of COVID-19 diagnosis. These findings were then compared with the presence of long COVID symptoms.Results: Among 54 study participants, 63% were non-elderly and 37% were elderly, with a nearly equal gender distribution. Notably, 74.1% of patients developed long COVID symptoms. The Brixia Score identified 38.9% as mild, 37% as moderate and 24.1% as severe lung involvement. Correspondingly, the Severity Score from chest CT scans revealed 33.3% with mild, 53.7% with moderate, and 13% with severe lung abnormalities. Statistical analysis confirmed strong correlations between both the Brixia Score (r = 0.553) and the Severity Score (r = 0.733) with the development of long COVID symptoms (p = 0.000).Conclusion: This study underscores the significant predictive value of both the Brixia Score and the Severity Score in identifying COVID-19 patients at risk of developing long COVID. These findings have critical implications for early risk stratification and targeted intervention strategies to prevent long COVID's debilitating effects.
Accuracy of Inhaler Use in COPD Patients and Factors Affecting It Indah Kusumawati Susanti; Rani Sauriasari; Anna Rozaliyani; Dodi Sudiana
Jurnal Respirologi Indonesia Vol 43, No 4 (2023)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/jri.v43i4.508

Abstract

Background: An inhaler is a type of dosage form used in the treatment of chronic obstructive pulmonary disease (COPD). The inhaler has a unique technique for use; however, the percentage of accuracy in inhaler use is still low. Proper inhaler use is expected to improve quality of life and decrease the occurrence of exacerbations. This study aimed to observe the percentage of accuracy in using inhalers and the factors that influence it.Method: This study was conducted with a cross-sectional design on COPD patients in two different hospitals. Primary data were collected using a questionnaire. The accuracy of inhaler use was assessed using a checklist.Results: The total number of patients in this study was 110, with an average age of 62 years. Patients were given single inhaler therapy, which included Dry Powder Inhalers (DPI) for 34 patients with 70.7% accuracy, Pressurized Metered-Dose Inhalers (pMDI) for 9 persons with 45.74% accuracy, and Soft Mist Inhalers (SMI) for one person with 66.67% accuracy. Furthermore, patients who used a combination of pMDI and DPI inhalers had an accuracy value of 68.53%, while a combination of pMDI and SMI had an accuracy value of 72.72%. The stage with the lowest level of accuracy in the pMDI-type inhaler used alone was exhaling before the inhaler was supplied.Conclusion:  According to the findings, the accuracy of inhaler use in COPD patients is still relatively low. Furthermore, gender is a factor that has a statistically significant relationship with inhaler accuracy.
Association of the Vaccination Status of Health Workers of COVID-19 Survivors with The Outcomes of Treatment of COVID-19 At General Hospital in Padang City Kornelis Aribowo; Masrul Basyar; Yessy Susanty Sabri
Jurnal Respirologi Indonesia Vol 43, No 3 (2023)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/jri.v43i3.351

Abstract

Background: Health workers are on the front lines of treating and fighting the COVID-19 pandemic. Health workers face COVID-19 patients at work. Health workers are at increased risk of infection if they are not properly protected. Increased risk for health workers can be caused by contact with patients without personal protective equipment (PPE) and surfaces contaminated with the virus. Infected health workers can infect other people around them and will increase the workload of other health workers. One of the efforts to reduce the risk of transmission to health workers is vaccination. Vaccines against COVID-19 are considered very important to prevent and control COVID-19. The aim is to determine the relationship between the COVID-19 vaccine status and the outcomes of healthcare workers treated for confirmed COVID-19 at hospitals throughout Padang.Methods: This observational study was conducted using a retrospective cohort method. The study was conducted from August 2021 to May 2022 in hospitals across Padang by completing a questionnaire in the form of a Google form link. Results: Vaccination status of health workers who survived COVID-19 who were treated at Padang City General Hospital (66.97%) were not vaccinated, aged 26–35 years (57.80%), female (80.73%), worked as paramedics (63, 55%), symptom onset 3 to 7 days (44.95%), number of symptoms 3 (55.96%), most fever (24.68%), number of comorbid 1 to 2 (66.06%), obesity (66.67%), length of stay <21 days (84.40%), and mild clinical (55.96%) and recovered (92.66%). The highest degree of COVID-19 severity for health workers who were not vaccinated was moderate clinical, 42 samples (57.53%), and vaccinated, predominantly mild clinical, 34 samples (94.44%). The duration of stay of health workers vaccinated was higher than that who were not vaccinated (97.22% vs. 78.08%).Conclusion: The vaccination status of health workers who have survived COVID-19 relates to a clinical degree, length of stay, and outpatient treatment.
The Effect of Inhaled Ipratropium Bromide as a Premedication For Bronchoscopy on Dyspnea, Cough, and Tracheobronchial Secretion Safina Mutmainnah; Yusup Subagio Sutanto; Jatu Aphridasari; A. Farih Raharjo
Jurnal Respirologi Indonesia Vol 43, No 4 (2023)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/jri.v43i4.256

Abstract

Background: Bronchoscopy is a minimally invasive procedure used for diagnostic examination and intervention of the airways. Patient comfort and cooperation during bronchoscopy are very important because they affect the success and outcome. The sympathetic anticholinergic effect of ipratropium bromide can improve procedure tolerance and airway visualization. This study was conducted to analyze the effect of inhaled ipratropium bromide as a bronchoscopy premedication for the assessment of dyspnea, cough, and tracheobronchial secretion.Methods: This was a clinical study with a quasi-experimental pretest-posttest control group design in pulmonary patients who underwent bronchoscopy at Dr. Moewardi General Hospital Surakarta in October 2021 using consecutive sampling. The subjects of the study were divided into an intervention group with inhaled ipratropium bromide and a control group without inhaled ipratropium bromide. The Borg scale of dyspnea and the visual analog scale (VAS) score of cough were assessed before and after bronchoscopy in both groups. The grading of tracheobronchial secretion was assessed during bronchoscopy.Results: Thirty-six pulmonary patients who underwent bronchoscopy were included in this study. The intervention group showed a lower Borg scale (0.28±0.57) and VAS score (3.22±8.54), lower tracheobronchial secretion grading, and there was a significant difference compared to the control (P≤0.05).Conclusion: There was a significant difference in the Borg scale of dyspnea, VAS score of cough, and the grading of tracheobronchial secretion in patients undergoing bronchoscopy as an effect of ipratropium bromide inhalation.
Correlation between Body Composition and Peak Expiratory Flow Rate in First-Year Medical Students of Diponegoro University Timothy Jordan; Darmawati Ayu Indraswari; Edwin Basyar; Buwono Puruhito
Jurnal Respirologi Indonesia Vol 43, No 3 (2023)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/jri.v43i3.517

Abstract

Background: Peak expiratory flow rate (PEFR) is one of the pulmonary ventilation parameters that affects quality of life. PEFR is known to be negatively affected by high body mass index (BMI) and waist circumference (WC). This study aimed to determine the correlation of BMI and WC with PEFR in first-year medical undergraduates at Diponegoro University.Methods: This was a cross-sectional study held from October 5th to October 8th, 2020, which measured the BMI, WC, and PEFR of 169 first-year medical students at Diponegoro University. The BMI, WC, and PEFR were assessed using a digital scale, measuring tape, and Mini-Wright peak flow meter (PFM), respectively. Spearman test was used for bivariate analysis, whereas the multiple regression method was used for multivariate analysis. The results are considered significant if P <0,05 for bivariate and F <0,05 for multivariate analysis. The IBM SPSS Statistics 26.0 Software was used for statistical analysis.Results: Most of the subjects had normal BMI, with a mean value of 23.38 (±0.36) kg/m2. As many as 71.6% of the subjects had normal WC. There was a correlation between BMI and PEFR (P = 0.001) with a weak strength (R = 0.260). As for BMI, WC also demonstrated a significant positive correlation (P <0.001) with a weak strength (R = 0.342) towards PEFR. Simultaneously, both BMI and WC had a significant positive correlation (F <0.001) with a weak strength (R = 0.361) towards PEFR.Conclusion: Higher BMI and WC values coincided with higher PEFR values. 
Bronchoalveolar Lavage (BAL) in Pulmonary Alveolar Proteinosis and Sarcoidosis Prasenohadi Prasenohadi
Jurnal Respirologi Indonesia Vol 43, No 4 (2023)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/jri.v43i4.607

Abstract

Bronchoalveolar lavage (BAL) is a minimally invasive procedure using flexible fiber optic bronchoscopy guidance that is safe, easily performed, and well tolerated. Bronchoalveolar lavage procedure is important to diagnose or differentially diagnose patients with a clinical appearance and radiological findings that are not specific. Mechanisms related to lung disorders such as inflammation, fibrosis, and abnormal material could be obtained by BAL fluid. Non-infection lung disorders such as pulmonary alveolar proteinosis (PAP) and sarcoidosis may be diagnosed by BAL. BAL in non-infection lung disease has diagnostic and therapeutic functions. As diagnostic function, BAL could be a tool to obtain a lower respiratory tract sample, and lavage from the respiratory track could be a therapeutic function of BAL.
Education on Inhaler Technique by Pharmacists To Improve The Quality of Life of COPD Patients: A Systematic Review and Meta-Analysis Sarah Almira; Vincent Pratama; Muh Ronike Yunus; Anna Rozaliyani; Rani Sauriasari
Jurnal Respirologi Indonesia Vol 43, No 4 (2023)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/jri.v43i4.479

Abstract

Background: This systematic review aimed to analyze the importance of education on using inhalers by pharmacists in improving quality of life, correct inhaler use steps, and medication adherence in patients with Chronic Obstructive Pulmonary Disease (COPD).Methods: The databases used to search for articles in this systematic review include Scopus, ScienceDirect, and Pubmed. The papers submitted were published between 2009 and 2022, with the most recent search being conducted in December 2022. This review included a randomized controlled trial evaluating education on inhaler use techniques by pharmacists to improve COPD patients' quality of life in inpatient and outpatient settings. This systematic review follows the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) writing guidelines.Results: This systematic review used six articles from five different countries. The articles involved share similar characteristics so that analysis can be carried out. The total number of research subjects included was 913 subjects. Most studies show an increase in the quality of life among COPD patients who are given education on how to use inhalers by pharmacists using print or digital media. Measurements using the St. George's Respiratory Questionnaire (SGRQ) showed a decrease in scores at the 6-month and 12-month periods (-0.75 [95% CI (-1.46 - (-.005)]. Furthermore, two articles reported that education on the technique of using inhalers by pharmacists can also increase the accuracy of using inhalers, and three articles reported increasing medication adherence.Conclusion: Interventions such as education on using inhalers by pharmacists in inpatient and outpatient settings can improve the quality of life of COPD patients, the accuracy of the steps in using inhalers, and medication adherence.
Correlation of Smoking with Carbon Monoxide Level and Peak Expiratory Flow Rate in High School Students Banda Aceh Julie Amalliah; Sri Dianova; Ferry Dwi Kurniawan; Teuku Zulfikar; Nurrahmah Yusuf
Jurnal Respirologi Indonesia Vol 43, No 3 (2023)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/jri.v43i3.294

Abstract

Background: Indonesia has the highest number of adolescent smokers in the world. Carbon monoxide (CO) is a by-product of tobacco smoking and is inhaled into the lungs. A smokerlyzer can monitor its level. Cigarette smoke also causes inflammation that affects airflow in the airways and can be detected by measuring the peak expiratory flow rate (PEFR). This study aims to determine the relationship between smoking and CO levels and PEFR in high school students in Banda Aceh City.Methods: This quantitative study uses an analytical observational approach with a cross-sectional design. This study involved 300 students from five senior high schools in Banda Aceh. The data were analyzed using the Mann-Whitney and Spearman test with a significance value <0.05.Results: CO levels of the smoker students were higher (12.61 ± 3.342 ppm) than nonsmoker students (2.46 ± 0.569 ppm), p=0.000. The average PEFR for smoking students was lower than nonsmokers (61.11 ± 9.163%) than for non-smoking students (78.48 ± 6.804 %), p=0.000. Duration of smoking in smoking students was also strongly associated with CO levels and PEFR (r=+0.749, p=0,000, r=-0.560, p=0.000, respectively).Conclusion: There is a relationship between smoking and CO levels and PEFR in senior high school students in Banda Aceh.
Analysis of Volatile Organic Compounds in the Exhaled Breath of COVID-19 Patients Tiar Oktavian Effendi; Iin Noor Chozin; Suryanti Dwi Pratiwi; Nanik Setijowati; Arinto Yudi Ponco Wardoyo
Jurnal Respirologi Indonesia Vol 43, No 4 (2023)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/jri.v43i4.394

Abstract

Background: It has been more than 2 years since COVID-19’s first cases were reported in 2019. Rapid diagnosis of COVID-19 is necessary to prevent its spread. A sample for COVID-19 testing is collected by naso-oro-pharyngeal swab. This procedure is often uncomfortable and requires a trained examiner. Exhaled breath contains thousands of volatile organic compounds (VOC), which are likely to change during infection. This study aimed to analyze the difference in VOC in the exhaled breath between COVID-19 and healthy subjects.Methods: A cross-sectional study was carried out, recruiting 90 confirmed cases of COVID-19 and 42 healthy subjects. A sample of exhaled breath was collected by using a 500-mL airbag in both groups. The sample was analyzed using an arrayed sensor breath analyzer to quantify the concentration of CO2, C7H8, C6H14, CH2O, NH4, TVOC, NO2, PM1.0, CO, NH3 ­and Acetone.Results: The medians of CO2, NH4, TVOC, NO2, and acetone were significantly lower in COVID-19 patients compared to healthy subjects (respectively 607.3 vs 1175.1; 0.0 vs 1.05; 0.05 vs 146.6; 0.04 vs 1.55; 0.0 vs 0.23) while C7H8, CH2O, CO, and NH3 were significantly higher (respectively 0.92 vs 0.0; 0.55 vs 0.01; 0.24 vs 0.0; 1.99 vs 0.67; all with P-value of <0.05.). Furthermore, we found NH4, acetone, NH3, and CO were positively correlated with the severity of COVID-19, while CO2 and TVOC were negatively correlated.Conclusion: COVID-19 patients emit distinctive VOC profiles in comparison with healthy subjects, and this is related to the severity of the disease.