ISM (Intisari Sains Medis) : Jurnal Kedokteran
Intisari Sains Medis is published by Medical Scientific Community, Indonesia. Intisari Sains Medis is an international, multidisciplinary, peer-reviewed, open access journal accepts papers for publication in all aspects of Science Digest, Medical Research Development, Research Medical Field and Theory. We also publish cases from third world country, that is considered very rare and special cases.
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<![CDATA[Evaluasi keberhasilan pengisian saluran akar dengan sediaan zinc oxide eugenol dan campuran calcium hydroxide dengan pasta iodoform ]]>
<![CDATA[Luh Wayan Ayu Rahaswanti]]>
<![CDATA[ Intisari Sains Medis Vol. 8 No. 1 (2017): (Available online: 1 April 2017) ]]>
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DOI: 10.15562/ism.v8i1.1
<![CDATA[Aim: the aim of this study was to investigate the succesful rate between Zinc Oxide Eugenol and Calcium Hydroxide with Iodoform Paste as root canal sealer for necrotic primary teeth. Method: pulpectomy procedures were conducted on 16 maxilary anterior teeth and for the obturation step, they were devided into two groups consist of 8 teeth. The first group of teeth were obturated with Zinc Oxide Eugenol sealer and the second group were obturated with Calcium Hydroxide with Iodoform Paste sealer. The data was taken on one month, two months, and three months after the treatment and then analized with Fisher’s Exact Test. Result: the result shows that there is no significant succesful rate between Zinc Oxide Eugenol and Calcium Hydroxide with Iodoform Paste as root canal sealer for necrotic primary teeth. Conclusion: the conclusion of this study is that both of Zinc Oxide Eugenol and Calcium Hydroxide with Iodoform Paste have similar efficacy in treating necrotic primary teeth.]]>
<![CDATA[Perbandingan Kekuatan Geser Braket Keramik Retensi dengan Perekatan Ulang dan Dua Teknik Pembersihan ]]>
<![CDATA[Louise Cinthia Hutomo]]>
<![CDATA[ Intisari Sains Medis Vol. 8 No. 1 (2017): (Available online: 1 April 2017) ]]>
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DOI: 10.15562/ism.v8i1.2
<![CDATA[Introduction: The purpose of this study is to measure the shear bond strength of rebonded mechanically retentive ceramic brackets prior which the base of the brackets was cleaned by two different methods. The first method was burnt out using spirituous lamp, the second method was burnt out using spirituous lamp and eventually sandblasted for 4 second. Methods: Thirty debonded ceramic brackets were prepared as the subject of this experiment. The shear bond strength was measured by Panke Pearson Equipment Limited, whereas the bond failure location of the rebonded brackets were examined using Zoom Stereo Microscope. T test was used to compare of the shear bond strength between two groups, whereas Chi Square analysis was used to determine the bond failure location of rebonded ceramic brackets. Results: Shear bond strength of rebonded ceramic brackets which were cleaned by second method was higher than those by first method, and had significant differences (p<0,01). Although the bond strength of rebonded ceramic brackets which were cleaned by first method was lower than the ones using second method, they were still above the clinical standard for intra oral retention. The bond failure location of rebonded ceramic brackets both by first method and second method after shear bond strength were tested, show no significant differences (p>0,05). The bond failure location of rebonded mechanically retentive ceramic brackets which cleaned by method I were mostly happen in the adhesive (86,7 %), and on the method n all the failure happens in the adhesive (100 %).]]>
<![CDATA[Tetrasiklin HCL Gel 0,7% meningkatkan jumlah sel fbroblas dan mempertebal ligamen periodontal pada sulkus gingiva tikus yang mengalami periodontitis ]]>
<![CDATA[I Gusti Agung Sri Pradnyani]]>
<![CDATA[ Intisari Sains Medis Vol. 8 No. 1 (2017): (Available online: 1 April 2017) ]]>
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DOI: 10.15562/ism.v8i1.3
<![CDATA[Periodontal disease is an infectious disease, could be result loose of the teeth. This research is to prove that the applying 0.7% tetracycline hcl gel on rat gingival sulcus result higher number of fibroblasts and collagen synthesis which are marked by the thicker of rat periodontal ligament. The study was a randomized post test only control group design experimental study on 32 white male rats which are inducted by lipopolyssaccaride (LPS) for 8 days. And then rats divided into control group were given placebo, and treatment group were given 0.7% tetracycline HCL gel. On 10th days, the rats were euthanazided for taken mandibula alveolar bone tissue sampling and histological preparations were made by HE (Harris Hematoxylin-Eosin) staining. The data were analyzed using SPSS program processed using Shapiro Wilk for normality test and then continued using independent t-test. The result of this research is the mean number of fibroblasts at treatment group by administration of 0.7% tetracycline HCL gel (148.38±5.11 units) was higher than the control group (113.19±5.39 units). The mean of collagen synthesis was showed by the thickness of periodontal ligamen at group treated 0.7% tetracycline HCL gel (338.65±57.28 µm) was higher than the control group (225.50±45.29 µm). The mean number of fibroblast cell and thickness of periodontal ligament were statistically different (p<0.05). Thus, it is concluded that 0.7% tetracycline HCL gel enhance the number of fibroblasts cell and the thickness of periodontal ligament in rat with periodontal disease.]]>
<![CDATA[Gambaran perilaku ibu dan sanitasi lingkungan terhadap kejadian diare pada balita di desa Banyubiru Kecamatan Negara Kabupaten Jembrana Bali 2014 ]]>
<![CDATA[I Made Yudi Mahardika]]>
<![CDATA[ Intisari Sains Medis Vol. 8 No. 1 (2017): (Available online: 1 April 2017) ]]>
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DOI: 10.15562/ism.v8i1.4
<![CDATA[Diarrhea is still potential to grow in Indonesia as a public health problem. In Bali, the prevalence of diarrhea in Jembrana ranks fourth highest. Negara Public Healthcare I have patients with high diarrhea disease. If the distribution of diarrhea cases in 2014 were reported to the Negara Public Healthcare I were analyzed by age group, the most visible cases of diarrhea suffered by a toddler groups, as many as 119 cases or 23% of the total 521 cases were settled in the village Banyubiru Jembrana District of the State. In order to anticipate this public health problem, Negara Public Healthcare I has implemented a range of activities covered by the Environmental Health Program, Disease Eradication Program, and the Community Health Promotion Program. The study was conducted in the Village area Banyubiru, District Negara, Jembrana in March-April 2014 using descriptive cross sectional study design with the interview method. The sample in this study were selected through simple random sampling technique. Based on research that has been done, it can be inferred picture characteristics, knowledge, maternal behavior, environment, and the incidence of diarrhea respondents with lower education, children under five suffer from diarrhea in infants in the village Banyubiru]]>
<![CDATA[Gambaran sikap dan perilaku merokok siswa SMA/SMK terhadap bahaya rokok pasca pencantuman gambar peringatan pada kemasan rokok di wilayah kerja upt puskesmas Mengwi I Kabupaten Badung Bali 2014 ]]>
<![CDATA[Putu Agus Sukarna]]>
<![CDATA[ Intisari Sains Medis Vol. 8 No. 1 (2017): (Available online: 1 April 2017) ]]>
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DOI: 10.15562/ism.v8i1.104
<![CDATA[Figures higher cigarette consumption in Indonesia is a crucial national issues. Indonesia is the fourth largest cigarette consuming country in the world after China, Russia and the United States. Number of cigarettes consumed reached 260.8 billion cigarettes per year.The prevalence of smokers aged adolescents reported increased from year to year. Data up to the year 2010 indicate that there is a pattern increased prevalence of smoking in adolescence. Increased reaching up to 12.9% of adolescents, especially in the age group 15-19 years. The prevalence of smoking in adolescent males increased by 24.6% (13.7% - 38.4%) and among girls increased by 0.6% (0.3% - 0.9%).Indonesian government imposed a new policy regarding the display cigarette packs stipulated in Government Regulation No. 109 of 2012 on securing material containing addictive substances such as tobacco products for health. In the policy set back the pictures warning of the dangers of smoking on cigarette packs are expanded to an area of 40% from 15% in the form of text.Research on the picture of the attitudes and behavior of SMA / SMK in Mengwi against the dangers of smoking after the inclusion of picture warnings on cigarette packs until now still not been done. Therefore, this study aims to describe the attitudes and behavior of SMA / SMK against the dangers of cigarettes post a picture had note warning the dangers of smoking in the work area UPT Puskesmas Mengwi 1 Badung ]]>
<![CDATA[Epilepsi bangkitan umum tonik-klonik di UGD RSUP Sanglah Denpasar-Bali ]]>
<![CDATA[Andre Kristanto]]>
<![CDATA[ Intisari Sains Medis Vol. 8 No. 1 (2017): (Available online: 1 April 2017) ]]>
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DOI: 10.15562/ism.v8i1.105
<![CDATA[Introduction: Epilepsy is a neurological disease that is characterized by episodes of seizures which can be accompanied by loss of consciousness of the patient. Although it is usually accompanied by loss of consciousness, there are several types of seizures without loss of consciousness. The disease is caused by the instability of electrical charges in the brain which in turn interfere with muscle coordination and manifest in muscle stiffness or repetitive pounding on the muscle. Classification of epileptic seizure according to ILAE 1981 include some general seizures, partial / focal seizures, and not classified seizures. Case: A 57-year-old woman, Balinese, come to the ER with complaints a limp, escorted by residents because of fainting. Patients do not know what happened so he brought the ER. Patients know who she is, what's her name, where she was, and the current time. Patient say she felt a little dizziness, no nausea, no vomiting. Patients are found to fall unconscious. At that time the patient was at work with his daily activity carrying stuff. Before fainting said patient lying at the scene while stamping hands and feet. Not checked how long the patient was lying. From families were dropping, the patient has a history of epilepsy, had been hospitalized in the hospital with a diagnosis of epilepsy, but never control the drug after the return of hospitalization.]]>
<![CDATA[Penatalaksanaan dan edukasi pasien sirosis hati dengan varises esofagus di rsup sanglah denpasar tahun 2014 ]]>
<![CDATA[Dita Mutia Fajarini Budhiarta]]>
<![CDATA[ Intisari Sains Medis Vol. 8 No. 1 (2017): (Available online: 1 April 2017) ]]>
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DOI: 10.15562/ism.v8i1.106
<![CDATA[Introduction: Cirrhosis is a chronic liver disease characterized by fibrosis is reversible, disorganization lobules and vascular structures, as well as regenerative nodules of hepatocytes. The overall incidence of cirrhosis in the United States an estimated 360 per 100,000 populations. The cause is largely due to alcoholic liver disease and chronic viral infections. Sarjito hospital in Yogyakarta, the number of patients with liver cirrhosis range in 4.1% of patients admitted to the internal medicine during the period of 1 year in 2004. Etiology of cirrhosis affects the handling of the disease. Therapy was carried out aimed at reducing disease progression, avoid ingredients that can add to liver damage, prevention and treatment of complications. Educating patients and families about the disease and the complications that may occur will greatly help improve treatment outcomes, and is expected to help improve the quality of life of patients. Case: Patient male, aged 43 years, Muslims, Madurese, came to the clinic and hospital with complaints of weakness since a week before coming, said to the entire body limp. This makes patients reluctant to perform daily activities. Patients also complain of pain in the gut. This pain is often felt after eating and drinking accompanied by nausea and vomiting, so patients are less appetite. Patients stated that the feeling of pain is also accompanied by a feeling of fullness in the abdomen. Frequency of urination is increased since the last few months, is said to be more than 4 times a day to urinate, but once the urinary volume of about ¼ cup aqua (240 cc) with a brownish color like tea. The desire to defecate patient is said to be normal.]]>
<![CDATA[Ekstrak etanol daun pandan wangi (pandanus amaryllifolius r.) 10% menurunkan immobility time dan kadar kortisol tikus jantan galur wistar yang depresi ]]>
<![CDATA[Lia Puspitasari]]>
<![CDATA[ Intisari Sains Medis Vol. 8 No. 1 (2017): (Available online: 1 April 2017) ]]>
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DOI: 10.15562/ism.v8i1.107
<![CDATA[Depression is an emotional and soul disorders that occurs due to abnormality of serotonine, norepinephrine, dopamine and cortisol levels in blood, urine and cerebrospinal fluid. Herb that assumed have antidepresant activity and able to normalise this abnormality condition is pandan leaf (Pandanus amaryllifolius R) with some secondary metabolites. The purpose of this reseach is to investigate the effect of pandan leaf extract in decreasing immobility time and cortisol levels in male wistar induced depression.This research used experimental laboratory pretest and posttest control group design, with 24 sample that divided into four group. Depression was inducted with tail suspention test method for 3 minutes a day in 10 days. Antidepressant activity observed by measurement of immobility time in forced swimming test method and analysis of cortisol levels with ELISA method. Based on the results of this research, ethanol extract of pandan leaves 10% able decreased immobility time for 45,26% (p<0,05) and decreased cortisol level for 33,24% (p<0,05). In t-paired test analysis, extract ethanol of pandan leaves 10% showed that there was an influence with this treatment in immobility time and cortisol level pretest and posttest data (p<0,05). Another result from this research showed that ethanol extract of pandan leaves 10% did not decrease immobility time and cortisol levels more better than positive control (amitriptilin treatment) p<0,005. It can be concluded that administration of extract ethanol pandan leaves 10% decreased immobility time and cortisol levels in depression male wistar rats.  ]]>
<![CDATA[Pemodelan perhitungan biaya pengadaan persediaan bahan baku menggunakan metode EOQ di perusahaan kosmetika ]]>
<![CDATA[I Gusti Ngurah Agung Dewantara]]>;
<![CDATA[N. P. A. D. Wijayanti]]>;
<![CDATA[A. A. Yastawa]]>
<![CDATA[ Intisari Sains Medis Vol. 8 No. 1 (2017): (Available online: 1 April 2017) ]]>
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DOI: 10.15562/ism.v8i1.108
<![CDATA[Background: The process of procurement of supplies is a very important in manufacturing company, without supplies, the company will face a difficult continuity of the production process. Aim: This research is to compare the amount of raw material purchase, frequency of purchase of raw materials, the frequency of delivery of raw materials, and the total cost of procurement of raw material inventories carried out using traditional methods and modeling methods EOQ in Cosmetics Company. Method: Data were collected using the data of the company in 2014-2015 and interviews with the owners and employees of the Company Cosmetics. Results: From this research is obtained the comparison of traditional methods and modeling EOQ ie the amount of raw material purchases in one message 1000kg: 8.440kg increased by 8.44 times, frequency of purchase of raw materials 24: 6 times, frequency of delivery of raw materials 24: 6 times. Conslusions: Total savings cost of raw material inventory control 70% of the total cost of procurement of raw material inventory by the company using traditional methods.]]>
<![CDATA[Pengukuran lipoprotein-associated phospholipase A2 sebagai alat diagnostik dan penentu prognosis ]]>
<![CDATA[Ardelia Yardhika]]>;
<![CDATA[Monik Alamanda]]>;
<![CDATA[Lisye Konny]]>
<![CDATA[ Intisari Sains Medis Vol. 8 No. 1 (2017): (Available online: 1 April 2017) ]]>
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DOI: 10.15562/ism.v8i1.110
<![CDATA[Pendahuluan: Penyakit kardiovaskular merupakan salah satu penyakit tidak menular utama dan menyebabkan 17,5 juta kematian setiap tahunnya. Pengukuran kadar biomarker inflamasi Lp-PLA2 dapat dilakukan untuk mengetahui risiko pembentukan aterosklerosis. Lp-PLA2 merupakan enzim spesifik inflamasi vaskular dan tidak dipengaruhi oleh inflamasi sistemik. Bahan dan Materi: Telaah sistematik dilakukan pada situs pencarian ProQuest, EBSCO, dan Google Scholar. Didapatkan 259 artikel jurnal yang kemudian dieksklusi menjadi 22 artikel yang kemudian dianalisis. Hasil dan Pembahasan: Deteksi pasien terkena aterosklerosis menggunakan kadar kolesterol dan CRP tidaklah akurat dan spesifik. Lp-PLA2 merupakan enzim yang spesifik berada pada pembuluh darah dan dapat menjadi biomarker baru untuk menentukan ada atau tidaknya aterosklerosis. Pengukuran Lp-PLA2 dapat dilakukan dengan mengukur massa dan aktivitas Lp-PLA2. Kesimpulan: Lp-PLA2 merupakan marker yang paling baik dibandingkan marker lainnya seperti kolesterol dan CRP untuk melihat risiko penyakit jantung koroner dan iskemik akibat aterosklerosis.]]>
