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Archives of The Medicine and Case Reports
Published by HM Publisher
ISSN : -     EISSN : 27472051     DOI : https://doi.org/10.37275/amcr
Core Subject : Health,
Health Professions Medicine & Pharmacology Nursing Public Health
Archives of The Medicine and Case Reports (AMCR) is a broad scope journal aims to publish the most exciting Case studies/reports in Clinical and Medical Sciences. AMCR aims to provide an excellent platform for Clinical Practitioners, medical/ health practitioners, students, professionals, researchers in medicine. AMCR accept any original case report that expands the field of general medical knowledge, and original research relating to case reports including report of the symptoms, diagnosis, treatment, and follow-up of an individual patient. The journal covers all medical specialties including : • Oncology • Paediatrics • Respiratory disorders • Allergy • Radiology • Nephrology • Neurology • Haematology • Immunology • Radiology • Nuclear medicine • Medical imaging • Audiovestibular medicine • Cardiology and cardiovascular systems • Critical care medicine • Dermatology • Emergency medicine • Endocrinology and metabolism • Gastroenterology and hepatology • Geriatrics and gerontology • Infectious diseases and treatment • Medical disorders in pregnancy • Medical ophthalmology • Sports Medicine • Substance abuse • Palliative medicine • Psychiatry • Rheumatology • Sexual and reproductive health
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 5 Documents
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Search results for , issue "Vol. 1 No. 1 (2020): Archives of The Medicine and Case Reports" : 5 Documents clear
Pemphigus Vulgaris Combination Adjuvant Therapy of Systemic Corticosteroid with Sparing Agent Sodium Mycophenolate Nopriyati; Cayadi Sidarta Antonius; Susanti Budiamal; Inda Astri Aryani
Archives of The Medicine and Case Reports Vol. 1 No. 1 (2020): Archives of The Medicine and Case Reports
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/amcr.v1i1.1

Abstract

Pemphigus Vulgaris(PV) is an autoimmune disease characterized by vesicles and bullae on the skin and mucosa resulting from an autoantibody reaction to desmosomal adhesion molecules desmoglein (Dsg) 1 and 3, which function as strong adhesions between keratinocytes. Pemphigus Vulgarisis more common in the fifth and sixth decades of age. The lesions are fragile blisters on the mucosa and skin. Diagnosing PV requires anamnesis, physical examination,and investigations such as histopathologic examination and direct immunofluorescence. Therapy generally uses steroids. Adjuvant treatmentis given to reduce the side effects of corticosteroids. We reported a male, 59 years old, was treated with blisters that break easily into blisters on the head, face, chest, back, groin and buttocks accompanied by burning and itching. In the scalp, facial, anterior et posteriortrunk, inguinal,and gluteal regions, multiple erythematous maculeswere found with lenticular-plaqueshape; it waspartially confluentwith thick brown crustswhich werechallengingto remove. The histopathologicexamination found the presence of suprabasal bullae with lymphocyte inflammation cells. The patient was diagnosed with PV and treated with corticosteroids with the sparing agent mycophenolate sodium andshowed clinical improvement. The first-linetreatment for pemphigus Vulgarisis systemic corticosteroids. Adjuvant sparing agent therapy is given to reduce the side effects of corticosteroids. Sodium mycophenolate sparing agent was selected because ofitsminimum side effects. In systemic management, the dose of corticosteroid and sparing agent mycophenolate sodium was gradually decreased. The patient experienced initial remission after treatment
Bipolar Type I Disorder in Children Syaiful Fadilah; Fatimah Haniman
Archives of The Medicine and Case Reports Vol. 1 No. 1 (2020): Archives of The Medicine and Case Reports
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/amcr.v1i1.2

Abstract

Bipolar disorder in children and adolescents is a clinical disorder that causes publicmental health problems that need attention. In the last decade, bipolar disorder inchildren and adolescents has become a trendy field, both in the clinical area and inresearch, especially in terms of diagnosis, which is still controversial. The controversythat remains is whether it is possible to diagnose bipolar disorder in prepubertalchildren. Based on the DSM-IV-TR diagnostic criteria, the prevalence of the bipolardisorder in children scarce rare. Epidemiological studies report the lifetimeprevalence of bipolar I and II disorders in late adolescence is about 1 per cent. Variousstudies in a large population have shown a prevalence rate of 0.1% -2%. The onsetof bipolar disorder in children and adolescents is often accompanied by a more severedisease course, compared to bipolar disorder with onset in adulthood. This casereport presents a case of bipolar 1 in children accompanied by comprehensivemanagement.
Preventive Treatment on Sexual Abuse Survivor with Mental Retardation Shinta Brisma; Nurmiati Amir
Archives of The Medicine and Case Reports Vol. 1 No. 1 (2020): Archives of The Medicine and Case Reports
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/amcr.v1i1.3

Abstract

The existence of limitations for children with mental retardation causes aninability to protect themselves so that they often become victims of sexualharassment. Preventive efforts are something that needs to be improved forprevention, considering the worse risks to children. The importance of an effortto prevent sexual abuse of children with mental retardation in connection withthe lack of knowledge about sexual abuse and the inability of children to facethe dangers that threaten themselves. From the results of research conductedin the United States in 1994, nearly 90% of children with mental retardationdisorders had experienced sexual abuse, as many as 49% had experiencedsexual abuse more than ten times. The high incidence of sexual abuseexperienced by children with mental retardation is due to various factors,namely the condition of children's limitations, lack of supervision andprotection of children by parents and the environment. Efforts that can be madeare increasing knowledge about sexual abuse and self-protection skills throughthe Behavioral Skills Training Group Program, where children are trained torecognize threatening objects and situations (sexual abuse). Increasingknowledge about sexual abuse and providing training (self-protection skills) isa significant primary preventive measure to reduce the risk of sexual abuse inchildren with mental retardation.
Right Frontotemporoccipital Focal Epilepsy with Behavioral and Emotional Problems Natalia Dewi
Archives of The Medicine and Case Reports Vol. 1 No. 1 (2020): Archives of The Medicine and Case Reports
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/amcr.v1i1.4

Abstract

Miss AN, female, 17 years old, Muslim, Betawi ethnicity, graduated from elementaryschool, currently no longer in school. The first febrile seizure patient was four yearsold. Five to seven years old, patients with recurrent seizures without fever, diagnosedwith epilepsy and do not see a doctor regularly. At 14 years, the patient was raped, andsince then, the patient has had free sex with many different men. At the age of,16, thepatient had seizures up to five times an ay, and one seizure was approximately fiveminutes. The patient went to a neurologist and was regularly treated with valproic acidand carbamazepine. At the age of 17 years, the patient often got angry when teased andthreatened with knives or scissors, had free sex with many men and went to apsychiatrist. The patient has been treated five times in different mental hospitalsbecause he often runs away from home. Currently, the patient is being treated in thepsychiatric ward and is receiving 2 x 500 mg of valproic acid, 3 x 200 mg ofcarbamazepine, 2 x 0.5 mg of Clonazepam and 1 x 50 mg of sertraline. At the time oftreatment, the patient is known to be HIV positive and does not need ARV therapy.Patients also planned behavioural therapy and involved patients with activities atYayasan Pelita Ilmu. It is hoped that this therapy can help overcome the patient'sbehavioural and emotional problems.
Polymorphism of p53 Codon 72 Gene on Cervical Cancer Incidence in Malay Population Lusia Hayati; Siska Delvia
Archives of The Medicine and Case Reports Vol. 1 No. 1 (2020): Archives of The Medicine and Case Reports
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/amcr.v1i1.5

Abstract

In Indonesia, the cases of cervical cancer are estimated at around 50 per 100.000 people. Itwas estimatedthattherearemore than 1 millionwomenworldwidewho have cervical cancer,and most of them have not been diagnosed yet or do not have access to screening and medicaltreatment. P53 codon 72 polymorphism can affect the risk of cervical cancer through theregulation of proliferationandcellapoptosis.The purpose of this research was to investigate theassociation between p53 codon 72 polymorphism and cases of cervical cancer. This researchwas observational analytic research. The research was done by examining in the laboratory ofMolecular Biology, Faculty of Medicine, Universitas Sriwijaya by using a case-control studyapproach.Thesampleoftheresearchconsistedof 70 subjects,and they were divided into twogroups:35 in case group and 35 in the control group. The determination of genotype andallotype was done by using PCR-RFLP technics. The results of the research showed there wasa significant difference between p53 codon 72 polymorphism between the case group andcontrol group. The results of genotypes of p53 codon 72 polymorphism in the case groupwere seven respondents (20.0%) with Pro/Pro genotype, five respondents (14.3%) withArg/Arg genotype, and 23 respondents (65.7%) with Pro/Arg. While in control group, there were28 respondents (80.0%) with Pro/Pro genotype, 0 respondent (0.0%) with Arg/Arg genotype,and 7 respondents (20%) with Pro/Arg. The frequency of the Prolin allele in case group was 37(52.9%), and the Arginin allele was 33 (47.1%), while the frequency of the Prolin allele in thecontrol group was 63 (90%), and the Arginin allele was 7 (10%). The Chi-Squareofgenotypewasvalued0.000,OR1,304andCI95%1,071-5,891,whiletheallelewas valued 0.000, OR 8.027 andCI 95% 3.228-19.962. There was anassociation between genotype and allele of p53 codon 72polymorphismandcases of cervicalcancer.

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