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Archives of The Medicine and Case Reports
Published by HM Publisher
ISSN : -     EISSN : 27472051     DOI : https://doi.org/10.37275/amcr
Core Subject : Health,
Health Professions Medicine & Pharmacology Nursing Public Health
Archives of The Medicine and Case Reports (AMCR) is a broad scope journal aims to publish the most exciting Case studies/reports in Clinical and Medical Sciences. AMCR aims to provide an excellent platform for Clinical Practitioners, medical/ health practitioners, students, professionals, researchers in medicine. AMCR accept any original case report that expands the field of general medical knowledge, and original research relating to case reports including report of the symptoms, diagnosis, treatment, and follow-up of an individual patient. The journal covers all medical specialties including : • Oncology • Paediatrics • Respiratory disorders • Allergy • Radiology • Nephrology • Neurology • Haematology • Immunology • Radiology • Nuclear medicine • Medical imaging • Audiovestibular medicine • Cardiology and cardiovascular systems • Critical care medicine • Dermatology • Emergency medicine • Endocrinology and metabolism • Gastroenterology and hepatology • Geriatrics and gerontology • Infectious diseases and treatment • Medical disorders in pregnancy • Medical ophthalmology • Sports Medicine • Substance abuse • Palliative medicine • Psychiatry • Rheumatology • Sexual and reproductive health
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 97 Documents
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Pemphigus Vulgaris Combination Adjuvant Therapy of Systemic Corticosteroid with Sparing Agent Sodium Mycophenolate Nopriyati; Cayadi Sidarta Antonius; Susanti Budiamal; Inda Astri Aryani
Archives of The Medicine and Case Reports Vol. 1 No. 1 (2020): Archives of The Medicine and Case Reports
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/amcr.v1i1.1

Abstract

Pemphigus Vulgaris(PV) is an autoimmune disease characterized by vesicles and bullae on the skin and mucosa resulting from an autoantibody reaction to desmosomal adhesion molecules desmoglein (Dsg) 1 and 3, which function as strong adhesions between keratinocytes. Pemphigus Vulgarisis more common in the fifth and sixth decades of age. The lesions are fragile blisters on the mucosa and skin. Diagnosing PV requires anamnesis, physical examination,and investigations such as histopathologic examination and direct immunofluorescence. Therapy generally uses steroids. Adjuvant treatmentis given to reduce the side effects of corticosteroids. We reported a male, 59 years old, was treated with blisters that break easily into blisters on the head, face, chest, back, groin and buttocks accompanied by burning and itching. In the scalp, facial, anterior et posteriortrunk, inguinal,and gluteal regions, multiple erythematous maculeswere found with lenticular-plaqueshape; it waspartially confluentwith thick brown crustswhich werechallengingto remove. The histopathologicexamination found the presence of suprabasal bullae with lymphocyte inflammation cells. The patient was diagnosed with PV and treated with corticosteroids with the sparing agent mycophenolate sodium andshowed clinical improvement. The first-linetreatment for pemphigus Vulgarisis systemic corticosteroids. Adjuvant sparing agent therapy is given to reduce the side effects of corticosteroids. Sodium mycophenolate sparing agent was selected because ofitsminimum side effects. In systemic management, the dose of corticosteroid and sparing agent mycophenolate sodium was gradually decreased. The patient experienced initial remission after treatment
Bipolar Type I Disorder in Children Syaiful Fadilah; Fatimah Haniman
Archives of The Medicine and Case Reports Vol. 1 No. 1 (2020): Archives of The Medicine and Case Reports
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/amcr.v1i1.2

Abstract

Bipolar disorder in children and adolescents is a clinical disorder that causes publicmental health problems that need attention. In the last decade, bipolar disorder inchildren and adolescents has become a trendy field, both in the clinical area and inresearch, especially in terms of diagnosis, which is still controversial. The controversythat remains is whether it is possible to diagnose bipolar disorder in prepubertalchildren. Based on the DSM-IV-TR diagnostic criteria, the prevalence of the bipolardisorder in children scarce rare. Epidemiological studies report the lifetimeprevalence of bipolar I and II disorders in late adolescence is about 1 per cent. Variousstudies in a large population have shown a prevalence rate of 0.1% -2%. The onsetof bipolar disorder in children and adolescents is often accompanied by a more severedisease course, compared to bipolar disorder with onset in adulthood. This casereport presents a case of bipolar 1 in children accompanied by comprehensivemanagement.
Preventive Treatment on Sexual Abuse Survivor with Mental Retardation Shinta Brisma; Nurmiati Amir
Archives of The Medicine and Case Reports Vol. 1 No. 1 (2020): Archives of The Medicine and Case Reports
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/amcr.v1i1.3

Abstract

The existence of limitations for children with mental retardation causes aninability to protect themselves so that they often become victims of sexualharassment. Preventive efforts are something that needs to be improved forprevention, considering the worse risks to children. The importance of an effortto prevent sexual abuse of children with mental retardation in connection withthe lack of knowledge about sexual abuse and the inability of children to facethe dangers that threaten themselves. From the results of research conductedin the United States in 1994, nearly 90% of children with mental retardationdisorders had experienced sexual abuse, as many as 49% had experiencedsexual abuse more than ten times. The high incidence of sexual abuseexperienced by children with mental retardation is due to various factors,namely the condition of children's limitations, lack of supervision andprotection of children by parents and the environment. Efforts that can be madeare increasing knowledge about sexual abuse and self-protection skills throughthe Behavioral Skills Training Group Program, where children are trained torecognize threatening objects and situations (sexual abuse). Increasingknowledge about sexual abuse and providing training (self-protection skills) isa significant primary preventive measure to reduce the risk of sexual abuse inchildren with mental retardation.
Right Frontotemporoccipital Focal Epilepsy with Behavioral and Emotional Problems Natalia Dewi
Archives of The Medicine and Case Reports Vol. 1 No. 1 (2020): Archives of The Medicine and Case Reports
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/amcr.v1i1.4

Abstract

Miss AN, female, 17 years old, Muslim, Betawi ethnicity, graduated from elementaryschool, currently no longer in school. The first febrile seizure patient was four yearsold. Five to seven years old, patients with recurrent seizures without fever, diagnosedwith epilepsy and do not see a doctor regularly. At 14 years, the patient was raped, andsince then, the patient has had free sex with many different men. At the age of,16, thepatient had seizures up to five times an ay, and one seizure was approximately fiveminutes. The patient went to a neurologist and was regularly treated with valproic acidand carbamazepine. At the age of 17 years, the patient often got angry when teased andthreatened with knives or scissors, had free sex with many men and went to apsychiatrist. The patient has been treated five times in different mental hospitalsbecause he often runs away from home. Currently, the patient is being treated in thepsychiatric ward and is receiving 2 x 500 mg of valproic acid, 3 x 200 mg ofcarbamazepine, 2 x 0.5 mg of Clonazepam and 1 x 50 mg of sertraline. At the time oftreatment, the patient is known to be HIV positive and does not need ARV therapy.Patients also planned behavioural therapy and involved patients with activities atYayasan Pelita Ilmu. It is hoped that this therapy can help overcome the patient'sbehavioural and emotional problems.
Polymorphism of p53 Codon 72 Gene on Cervical Cancer Incidence in Malay Population Lusia Hayati; Siska Delvia
Archives of The Medicine and Case Reports Vol. 1 No. 1 (2020): Archives of The Medicine and Case Reports
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/amcr.v1i1.5

Abstract

In Indonesia, the cases of cervical cancer are estimated at around 50 per 100.000 people. Itwas estimatedthattherearemore than 1 millionwomenworldwidewho have cervical cancer,and most of them have not been diagnosed yet or do not have access to screening and medicaltreatment. P53 codon 72 polymorphism can affect the risk of cervical cancer through theregulation of proliferationandcellapoptosis.The purpose of this research was to investigate theassociation between p53 codon 72 polymorphism and cases of cervical cancer. This researchwas observational analytic research. The research was done by examining in the laboratory ofMolecular Biology, Faculty of Medicine, Universitas Sriwijaya by using a case-control studyapproach.Thesampleoftheresearchconsistedof 70 subjects,and they were divided into twogroups:35 in case group and 35 in the control group. The determination of genotype andallotype was done by using PCR-RFLP technics. The results of the research showed there wasa significant difference between p53 codon 72 polymorphism between the case group andcontrol group. The results of genotypes of p53 codon 72 polymorphism in the case groupwere seven respondents (20.0%) with Pro/Pro genotype, five respondents (14.3%) withArg/Arg genotype, and 23 respondents (65.7%) with Pro/Arg. While in control group, there were28 respondents (80.0%) with Pro/Pro genotype, 0 respondent (0.0%) with Arg/Arg genotype,and 7 respondents (20%) with Pro/Arg. The frequency of the Prolin allele in case group was 37(52.9%), and the Arginin allele was 33 (47.1%), while the frequency of the Prolin allele in thecontrol group was 63 (90%), and the Arginin allele was 7 (10%). The Chi-Squareofgenotypewasvalued0.000,OR1,304andCI95%1,071-5,891,whiletheallelewas valued 0.000, OR 8.027 andCI 95% 3.228-19.962. There was anassociation between genotype and allele of p53 codon 72polymorphismandcases of cervicalcancer.
Decompensated Acute Heart Failure Accompanied with Cardiac Cirrhosis and Chronic Disease Anemia in Child Tommy Darmasaputra
Archives of The Medicine and Case Reports Vol. 1 No. 2 (2020): Archives of The Medicine and Case Reports
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/amcr.v1i2.6

Abstract

Continuous heart failure can lead to complications to other systems, one of which is the hepatic system. Heart failure results in venous congestion in the portal vein so that the portal vein pressure increases, which is called portal hypertension. Portal hypertension causes fluid to pass through the walls of blood vessels and into the tissues. Management of decompensatory heart failure accompanied by comorbi d disease in cardiac cirrhosis includes drugs management that does not aggravate the liver, namely angiotensin converting enzyme inhibitors and loop diuretic agents. Also, non-pharmacological management such as resting position and a diet sufficient in protein and low salt help improve the patient's general condition. This case report aims to present a de compensated heart failure accompanied by cardiac cirrhosis and anaemia of chronic disease in a child.
Case Report: Magic Mushroom (Psilocybe cubensis) Intoxication Andrian Fajar Kusumadewi
Archives of The Medicine and Case Reports Vol. 1 No. 2 (2020): Archives of The Medicine and Case Reports
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/amcr.v1i2.7

Abstract

Psilocybe mushroom, or widely known as the magic mushroom is a variety of mushroom commonly consumed because of hallucinogenic traits it causes toward its consumer. This hallucinogenic effect is caused by Psilocybin, a hallucinogenic substance often found within Psilocybe mushroom. This substance affects mental state of the consumer and has similar effect to those of LSD and Mescaline. Aside from its effect to cause mental disturbance, consumption of this mushroom may cause acute renal injury which leads to a fatal and life-threatening situation. A case of Psilocybe intoxication had been reported in a 22 years old male with a confirmed history of consuming Psilocybe mushroom. Patient first came with a symptom of disorientation and restlessness. Patient also often shook his head off, laughed out, screamed, and continuously making bizarre movements. Psychiatric examination confirmed a sign of auditory hallucination, unstable mood, and stereotypical behavior experienced by the patient. This case report was intended to elaborate the effects of Psilocybe mushroom consumption against physical and mental condition of the consumer, and its management in clinical settings.
The Correlation between Alcohol Consumption with Anxiety Level on Multiple Drugs User in Sleman Andrian Fajar Kusumadewi; Carissa Aulia Firliany; Silas Henry Ismanto; Afkar Aulia
Archives of The Medicine and Case Reports Vol. 1 No. 2 (2020): Archives of The Medicine and Case Reports
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/amcr.v1i2.8

Abstract

Since 2013, data showed alcohol consumption in Indonesia increased from 3% to 3.3%, and 0.8% of the population consumes alcohol over the limit (Riskesdas 2018). Consuming alcohol over the limit not only impacts someone physically but also mentally. One of the mental impacts of alcohol consumption is anxiety. If the anxiety is not treated properly, it can lead a patient to consume more alcohol and, moreover, develop an alcohol addiction. To examine alcohol consumption levels and their correlation to anxiety levels. This study is analytical research with a quantitative cross-sectional survey design. Sampling techniques were done by consecutive sampling with the AUDIT questionnaire survey to measure alcohol consumption level and the T-MAS questionnaire survey to measure anxiety level of respondents. The research sample consists of 30 multiple drug user respondents. We got a 0.569 p-value score with Pearson Chi-Square analysis, which can be interpreted to mean that there is no correlation between alcohol consumption and anxiety level. Patients with alcohol abuse mostly come from low-to-average academic groups, a total of 29 people, and not married groups, a total of 18. There is no correlation between alcohol consumption and anxiety levels. The respondent's anxiety level is influenced by his or her academic grade and marital status.
Assesment of Antioxidant Activity Test of Kersen Leaf (The phenolic.) and Epiphyte with DPPH (2.2-Diphenyl-1-Picrylhidrazyl) Nurlutfiyyah Aini; Nita Parisa; Fatmawati
Archives of The Medicine and Case Reports Vol. 1 No. 2 (2020): Archives of The Medicine and Case Reports
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/amcr.v1i2.9

Abstract

Antioxidant is very important to give protection against free radical activity and highly reactive molecules that could lead in slowing the progression of degenerative disease. In case of degenerative disease, internal antioxidant cannot neutralize the increasing concentration of free radical. Because of that, human needs external antioxidant. Kersen (Muntingia calabura L.) is a plant that is known for its antioxidant content. Plants containing antioxidant experience is kersen (Muntingia calabura L.). Research study to determine the antioxidant activity of Kersen plant and knows the difference of antioxidant activity, based on the process of extract and infusion. Research was done by experimental study which was oriented in testing antioxidant activity in (Morinda citrifolia L.) extract and infusion. Extraction was done by using 96% ethanol as solvent meanwhile infusion was made by using aquadest. Extract and infusion were divided into group of concentration and antioxidant activity was tested by DPPH(2,2-Diphenyl-1-Picrylhidrazyl) method by measuring the absorbance using spectrophotometer at 520 nm wavelength. Percentage of DPPH inhibition and IC50 then analyze d using linear regression analysis. Ethanolic extract of kersen leaf and epiphyte had IC50 value of 113,801 ppm and 98,7802 ppm, respectively. Kersen leaf infusion showed 191,7624 ppm IC50 values, besides its epiphyte had 131,6750 ppm. Antioxidant activity of Muntingia calabura L. in the order from kersen leaf an epiphyte and epiphyte extract has a higher antioxidant content than others.
Patterns of Using Analgesics for Menstrual Pain in Female Students Sriwijaya University Faculty of Medicine Nita Parisa; M. Khairul Kahfi Pasaribu; Bintang Arroyantri Prananjaya; Ardesy Melizah Kurniati; Ziske Maritska
Archives of The Medicine and Case Reports Vol. 1 No. 2 (2020): Archives of The Medicine and Case Reports
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/amcr.v1i2.10

Abstract

Dysmenorrhea is a condition that women often feel at their productive age and disrupt their daily activity. A study that was condoned in Palembang finds that 93,8% of SMA female students had dysmenorrhea. A study in India finds that 42% in 654 respondents decided to their dysmenorrhea without visiting a physician and 35% are using the wrong medication Analgetics as a pain reliever sold freely in markets. Dysmenorrhea affects life quality and education for the easiness in obtaining medicine in markets, making the research about analgetics usage patterns in Faculty of Medicine, Sriwijaya University 2016-201 students. The design of this study was cross-sectional descriptive observational from 2 December 2019 until 6 January 2020. The population of this study is FK Unsri (201 2019) students with 628 respondents. The respondent characteristics are found by using a questionnaire. Dysmenorrhea prevalence among FK UNSRI students is 88%. Dysmenorrheprevalence that disrupts activity is 64,7%. FK UNS RI student (2016-2019) that use mefenamic acid is 48,3%, paracetamol is 33,8% and ibuprofen is 6,2% for the dysmenorrhea.FK UNSRI student (2016-2019) that consumed analgetics once per day 80,6%. FK UNSRI students (2016-2019) that picked tablets is 97,9%. FK UNSRI study (2016- 2019) that chose to use it for a day is 76,5%. The analgetics that are mostly chosen for FK UNSRI (2016-2019) students are mefenamic acid, a tablet that was consumed once per day for a day.

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