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Tropical Health and Medical Research Journal
Published by Baiman Bauntung Batuah Center
ISSN : -     EISSN : 2684740X     DOI : https://doi.org/10.35916/thmr.v1i1
Core Subject : Religion, Health, Science,
Religion Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health
Tropical Health and Medical Research is an open access, peer-reviewed journal that publishing only original research on all aspects of tropical medicine and global health especially health related to the Muslim community. Journal content including viral, bacterial and parasitic infectious diseases, Vectors, Noncommunicable diseases, Epidemiology and population health, Drug, vaccine and diagnostic tool development, Other health issues related to the Muslim community
Arjuna Subject : Profesi Kesehatan - Teknologi Laboratorium Medis
Articles 6 Documents
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Search results for , issue "Vol. 2 No. 2 (2020): Tropical Health and Medical Research" : 6 Documents clear
Investigation of Biliary Canal Variations as a Cause of Stone Formation in the Choledochal Canal M. Sabri Medişoğlu; Çolak Tuncay; Yalnız Ahmet; Çam İsa; Sezikli Mesut; Yusuf Atakan Baltrak
Tropical Health and Medical Research Vol. 2 No. 2 (2020): Tropical Health and Medical Research
Publisher : Baiman Bauntung Batuah Center

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (248.967 KB) | DOI: 10.35916/thmr.v0i0.18

Abstract

The present study aimed to investigate if there is an association between the diameter of the choledochal duct and choledochal duct stone formation. The present study consisted of 79 patients who had endoscopic interventions and MRCP procedure with surgery history. Some followed due to disorders of the liver, gall bladder, and biliary tract and some of whom presented hepatobiliary complaints between 2017 and 2019. The choledochal duct diameter measured from MRCP images and choledochal duct stone had examined; the type classified according to Huang classification. Among the cases classified, 29 patients, was Huang Type A1, 27 patients were Huang Type A2, 16 patients were Huang Type A3, and seven patients were Huang Type A4. There was not any statistically significant association in terms of choledochal diameter regarding the types. Choledochal duct diameter was statistically higher in female patients than male patients (p<0.05). According to the age group, a statistically significant difference detected for choledochal duct stone formation; individuals over 45 years of age present an increase for choledochal duct stone (p<0.05). The choledochal duct diameter was found higher in female patients compared with male patients; stone formation has found increased in both gender over 45 years of age. It should consider before surgical procedures and radiological tests.
Sleep Quality of Diabetic Patients with Metabolic Syndrome, is There a Difference? Savas Karatas; Aysun Işıklar
Tropical Health and Medical Research Vol. 2 No. 2 (2020): Tropical Health and Medical Research
Publisher : Baiman Bauntung Batuah Center

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (229.448 KB) | DOI: 10.35916/thmr.v0i0.19

Abstract

Poor sleep quality is a prevalent health problem among patients with diabetes. Metabolic syndrome (MetS) is common in type 2 diabetic patients and associated with morbidity and mortality. We aimed to investigate sleep quality among type 2 diabetes patients according to their metabolic syndrome status. This was an analysis of data collected from 189 adult type 2 diabetic patients. The patients divided into two groups (metabolic and non-metabolic) based on the presence of MetS. Anthropometric measurements, blood pressure, and serum glucose, lipid levels were collected. The Pittsburgh Sleep Quality Index (PSQI) calculated for all patients. There was no significant difference in subjective sleep quality scores between the two groups (p > 0.05). However, there was a significant difference in sleep latency scores between the two groups; the scores of patients with MetS were lower than those of patients without MetS (p = 0.010, p < 0.05).Sleep quality was low in 57.1% (n = 108) of patients with diabetes. Poor sleep is common among diabetic patients, but in this study, metabolic syndrome existence not associated with sleep quality in type 2 diabetic patients.
Ophthalmological Findings in Paediatric Non-Traumatic Coma in Enugu State University Teaching Hospital, Parklane, Enugu, Nigeria Ikenna Kingsley Ndu; Ifeoma N Asimadu; Benedict Onyeka Edelu; Obinna Chukwuebuka Nduagubam; Ogechukwu F Amadi; Isaac Nwabueze Asinobi; Uchenna Ekwochi
Tropical Health and Medical Research Vol. 2 No. 2 (2020): Tropical Health and Medical Research
Publisher : Baiman Bauntung Batuah Center

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (142.65 KB) | DOI: 10.35916/thmr.v0i0.20

Abstract

The ophthalmological examination is a vital aspect of the central nervous system examination in comatose children. Several authors have documented different findings with disparities in their recommendations about making ophthalmological examination a routine in the management of the unconscious child. This study sought to evaluate the relevance of routine ophthalmological examination in the management of unconscious children admitted into the paediatric emergency room of Enugu State University Teaching Hospital, Parklane, Enugu, Nigeria. This was a prospective longitudinal study conducted from April 2018 to March 2019. Unconscious patients whose caregivers gave consent were recruited into the study. Traumatic causes of coma were excluded. Demographic features of the patients were obtained. The ophthalmologic examination and diagnoses were made by an ophthalmologist, while the emergency room pediatrician made clinical assessment and diagnoses. Sixteen unconscious children had ophthalmologic examinations done. The Glasgow coma scale scores ranged from 3 to 11, with a mean of 6.6±2.2. Thirteen (81.3%) of the children were classified as severe unconsciousness while the rest were moderate. The degree of unconsciousness was significantly associated with the outcome (?2 =16.0, P = 0.03). A total of six (37.5%) ophthalmologic diagnoses were made, which included cerebral malaria, degenerative myopia, orbital cellulitis, and exposure keratopathy. The presence of an abnormal ophthalmologic finding was not significantly associated with outcome (?2 =0.36, P = 0.55). Routine ophthalmologic examination may not be justified as a management protocol in unconscious children but may be considered in selected cases.
Garlic Extract (Allium sativum L.) Effectively Inhibits Staphylococcus aureus and Escherichia coli by Invitro Test Agnina Listya Anggraini; Ratih Dewi Dwiyanti; Anny Thuraidah
Tropical Health and Medical Research Vol. 2 No. 2 (2020): Tropical Health and Medical Research
Publisher : Baiman Bauntung Batuah Center

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (258.775 KB) | DOI: 10.35916/thmr.v0i0.22

Abstract

Infection is a disease caused by the presence of pathogenic microbes, including Staphylococcus aureus and Escherichia coli. Garlic (Allium sativum L.) has chemical contents such as allicin, alkaloids, flavonoids, saponins, tannins, and steroids, which can function as an antibacterial against Staphylococcus aureus and Escherichia coli. This study aims to determine the antibacterial properties of garlic extract powder against Staphylococcus aureus and Escherichia coli. This research is the initial stage of the development of herbal medicines to treat Staphylococcus aureus and Escherichia coli infections. The antibacterial activity test was carried out by the liquid dilution method. The concentrations used were 30 mg/mL, 40 mg/mL, 50 mg/mL, 60 mg/mL and 70 mg/mL. The results showed that the Minimum Inhibitory Concentration (MIC) against Staphylococcus aureus and Escherichia coli was 40 mg/mL and 50 mg / mL. Minimum Bactericidal Concentration (MBC) results for Staphylococcus aureus and Escherichia coli are 50 mg/mL and 70 mg/mL. Based on the Simple Linear Regression test, the R2 value of Staphylococcus aureus and Escherichia coli is 0.545 and 0.785, so it can be concluded that there is an effect of garlic extract powder on the growth of Staphylococcus aureus and Escherichia coli by 54.5% and 78.5%. Garlic (Allium sativum L.) extract powder has potential as herbal medicine against bacterial infections but requires further research to determine its effect in vivo.
Ethanol Extract Of Centella Asiatica (L.) Urban Leaves Effectively Inhibit Streptococcus pyogenes and Pseudomonas aeruginosa by Invitro Test Dini Aulia Azmi; Nurlailah Nurlailah; Ratih Dewi Dwiyanti
Tropical Health and Medical Research Vol. 2 No. 2 (2020): Tropical Health and Medical Research
Publisher : Baiman Bauntung Batuah Center

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (234.893 KB) | DOI: 10.35916/thmr.v0i0.23

Abstract

Streptococcus pyogenes and Pseudomonas aeruginosa are some of the causes of infectious diseases. Centella asiatica (L.) Urban has many benefits for humans, including overcoming fever, anti-bacterial, and anti-inflammatory. This study aims to determine the inhibition of Centella asiatica (L.) Urban leaves ethanol extract on the growth of Streptococcus pyogenes and Pseudomonas aeruginosa. This research is the initial stage of the development of herbal medicines to treat Streptococcus pyogenes and Pseudomonas aeruginosa infections. The independent variable was the concentration of ethanol extract of Centella asiatica (L.) Urban leaves and the dependent variable was the growth of Streptococcus pyogenes and Pseudomonas aeruginosa. The anti-bacterial activity test was carried out by the liquid dilution method. The concentrations used are 20%, 40%, 60%, 80%. 100% The results showed that the minimum inhibitory concentration (MIC) against Streptococcus pyogenes: 40% and Pseudomonas aeruginosa: 40%. Minimum bactericidal concentration (MBC) results for Streptococcus pyogenes: 60% and Pseudomonas aeruginosa: 60%. So it can be concluded that there is inhibition of the ethanol extract of Centella asiatica (L.) Urban leaves on the growth of Streptococcus pyogenes and Pseudomonas aeruginosa. Centella Asiatica (L.) Urban extract has potential as herbal medicine against bacterial infections but requires further research to determine its effect in vivo.
Renal Tubular Dysfunction Linked to Tenofovir in Antiretroviral Therapy in HIV-Infected Patients Renato Ferneda de Souza; Fernando Gongora Rubio
Tropical Health and Medical Research Vol. 2 No. 2 (2020): Tropical Health and Medical Research
Publisher : Baiman Bauntung Batuah Center

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (184.628 KB) | DOI: 10.35916/thmr.v0i0.24

Abstract

Introduction: tenofovir disoproxil fumarate (TDF) has low general toxicity and can lead to moderate reduction in glomerular filtration rate (GFR) and a larger prevalence of renal tubular dysfunction (RTD). The mechanism of RTD has been attributed to the mitocondrial lesion in the proximal tubule cells caused by the increase of the intracelular TDF concentration. Aditionaly, host´s genetic polymorphisms have been considered one of the TDF concentration increasing causes. RTD can be characterized by the deficiency in the solutes reabsorption as bicarbonate, uric acid, phosphate, glucose and low weight molecular proteins. Objectives: verify the prevalence of renal tubular dysfunction in the people living with HIV (PLWH) on TDF treatment, identify the risk factors associated and compare the 24-hours urine findings with the serum creatinine and its calculated clearance for the RTD identification. Methods: prospective case control study, performed between january 2011 to december 2015. Results: 163 patients were included in the study, in which 106 (68.4%) didn't use TDF and 57 (31.6%) used TDF. RTD occured in 8 patients that used TDF, a prevalence of 14%. The patients age was identified as significant risk factor for the development of RTD. Proteinuria and the phosphaturia were significant for the diagnosis of RTD. Conclusions: age was determined as risk factor for RTD, mainly in patients over 60 years-old. Phosphaturia and proteinuria showed the greatest diagnosis sensitivity for RTD. The serum creatinine and phosphorus concentration, the creatinine clearance and the stand alone hyperproteinuria should not be used as diagnosis predictors for RTD.

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