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Tropical Health and Medical Research Journal
Published by Baiman Bauntung Batuah Center
ISSN : -     EISSN : 2684740X     DOI : https://doi.org/10.35916/thmr.v1i1
Core Subject : Religion, Health, Science,
Religion Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health
Tropical Health and Medical Research is an open access, peer-reviewed journal that publishing only original research on all aspects of tropical medicine and global health especially health related to the Muslim community. Journal content including viral, bacterial and parasitic infectious diseases, Vectors, Noncommunicable diseases, Epidemiology and population health, Drug, vaccine and diagnostic tool development, Other health issues related to the Muslim community
Arjuna Subject : Profesi Kesehatan - Teknologi Laboratorium Medis
Articles 5 Documents
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Search results for , issue "Vol. 4 No. 1 (2022): Tropical Health and Medical Research" : 5 Documents clear
Effects of Homemade Nano-Hydroxyapatite and Olive Oil Paste on Remineralization of Early Caries Lesions Ayşe Dina Erdilek; Sevdiye Burke; Merve Şahin; Ata Efes; Begüm Güray Efes
Tropical Health and Medical Research Vol. 4 No. 1 (2022): Tropical Health and Medical Research
Publisher : Baiman Bauntung Batuah Center

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (205.767 KB) | DOI: 10.35916/thmr.v4i1.57

Abstract

Nano-hydroxyapatite (nHAP) particles are a new generation of materials reported to remineralize enamel lesions. The purpose we aimed was to compare the in vitro effects of fluoride gel, sodium fluoride toothpaste, and homemade nHAP paste on remineralizing artificial early enamel caries. Methods:  Incipient caries were induced in 21 extracted, sound premolar teeth by storing each specimen in a demineralization solution for 72 hours, followed by pH cycling. The samples (n= 7, each) were then treated with 2% neutral fluoride gel, 0.25% sodium fluoride toothpaste, or homemade nHAP paste, comprising a mixture of nHAP powder and olive oil. After demineralization and remineralization, the results were compared using the DIAGNOdent pen (KaVo, Germany). The data were statistically analyzed using paired t-tests and a one-way ANOVA test. Outcomes: The degree of demineralization in each of the three groups (fluoride gel group, 15.71; sodium fluoride dentifrice group, 15.28; nHAP paste group, 16.71) was significantly elevated compared to baseline (3, 2.5, 2.28, respectively); however, no significant difference was observed between the remineralization readings in each of the three groups (6, 7, 5.5, respectively) (p > 0.05). In conclusion, we concluded that the homemade nHAP paste had a beneficial effect on the remineralization of initial enamel caries lesions.
Prevalence and Comorbidity of Adult Attention Deficit and Hyperactivity Disorder Among the Patients Applying to Kocaeli University’s Psychiatry Polyclinic Başak Küçük; Buket Özkara Yilmaz
Tropical Health and Medical Research Vol. 4 No. 1 (2022): Tropical Health and Medical Research
Publisher : Baiman Bauntung Batuah Center

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35916/thmr.v4i1.58

Abstract

The present study aimed to determine the prevalence of ADHD diagnosis among the patients applying to adult psychiatry polyclinic for the first time and to determine comorbid diseases among the patients diagnosed with ADHD. The present study was carried out on patients who applied to the Psychiatry Polyclinic in the Medical Faculty Hospital of Kocaeli University Turkey between 10.01.2018 and 03.01.2019, with 151 patients involved in this study. After providing the participating patients with a verbal and written briefing about the study, the Sociodemographic Information Form and AADHDS were given to the participants. DIVA2.0 Adult ADHD Diagnostic Interview Scale and SCID-1 were implemented. As found in DIVA 2.0 ADHD Diagnostic Interview Form for Adults, 19.9% of 151 patients were diagnosed with adult ADHD, and 80.1% were not. Given SCID-1 diagnoses of patients, it was determined that, of the patients diagnosed with ADHD, 16.6% were diagnosed with depression, followed by generalized anxiety disorder (10%), and panic disorder and depression (10%), and that 13.3% of participants were not diagnosed with another disorder. Participants diagnosed with ADHD were found to have lower mean age. Prevalence of ADHD diagnosis was found to be lower among singles and students. The individuals diagnosed with ADHD were found to have a more prolonged education period. The prevalence of ADHD was higher among those who received a disciplinary punishment. Making an accurate diagnosis, designing an appropriate treatment, and determining the comorbidities of ADHD and with which psychiatric disorders it is confused would positively contribute to outcomes of treatments and increase the patients’ quality of life.
Fungicidal Effects of Chloroform Extract of Red Galangal (Alpinia purpurata (Vieill.) K. Sch) on the Growth of Trichophyton rubrum Nur Asy Syifa Azizah; Anny Thuraidah; Ratih Dewi Dwiyanti
Tropical Health and Medical Research Vol. 4 No. 1 (2022): Tropical Health and Medical Research
Publisher : Baiman Bauntung Batuah Center

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35916/thmr.v4i1.59

Abstract

Trichophyton rubrum is the most common causative agent of anthropophilic dermatophytosis worldwide. Treatment of dermatophytosis can use natural ingredients. In Indonesia, several medicinal plants have been used, one of which is red galangal (Alpinia purpurata (Vieill.) K. Sch). This study aims to determine the effectiveness of red galangal rhizome chloroform extract on the growth of Trichophyton rubrum. This study is a True Experiment study with Posttest Only With Control Group Design consisting of 8 treatments namely positive control, extract control, 0 mg/mL (negative control), 20 mg/mL, 30 mg/mL, 40 mg/mL, 50 mg/ml, and 60 mg/mL extract of red galangal rhizome chloroform with 3 repetitions. The antifungal activity test was carried out using the determination of Minimum Inhibitory Concentration (MIC), Minimum Fungicidal Concentration (MFC), and Bioautography Test. The results showed that the red galangal rhizome chloroform extract in the Agar Overlay Bioautography Test contained an inhibition zone on the growth of Trichophyton rubrum. The determination of MIC and MFC were 20 mg/mL and 40 mg/mL, respectively. The study concludes that the red galangal rhizome chloroform extract affects the growth of the fungus Trichophyton rubrum. Research can be continued by knowing more specifics about the bioactive compounds from the red galangal rhizome, which have antifungal activity against Trichophyton rubrum.
The Potential at Phytochemical Compounds from the Indonesian Kalimantan Plant as Covid-19 Immunomodulators Chairana Fadya; Ahmad Luthfi Haqiqi; Annisa Miladdiannur; Monika Yati; Ummu Salamah Az Zahra; Neni Oktiyani; Wahdah Norsiah
Tropical Health and Medical Research Vol. 4 No. 1 (2022): Tropical Health and Medical Research
Publisher : Baiman Bauntung Batuah Center

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35916/thmr.v4i1.60

Abstract

Herbal plants are alternative medicine and immunity boosters related to the Covid-19 pandemic. Typical Kalimantan plants that have the potential are dayak onion (Eleutherine americana Merr.), karamunting (Rhodomyrtus tematosa (Aiton) Hassk), pasak bumi (Eurycoma longifolia Jack), and tigaron (Crataeva adansonii DC). This study aims to determine the potential of phytochemical compounds from Indonesian Kalimantan plants as Covid-19 immunomodulators. Descriptive research with cross-sectional study design by testing the typical plants of Kalimantan, which were extracted first through the maceration method and then carried out qualitative and quantitative phytochemical tests. Qualitative and quantitative results showed that the four positive plants contained phytochemical alkaloids, flavonoids, saponins, and tannins in certain levels. Quantitative results on dayak onion (Eleutherine americana Merr.) obtained alkaloid content; flavonoids; saponins; tannins were 74.540%; 22.125 mg/mL; 58.350%; 0.342 mg/mL. karamunting fruit (Rhodomyrtus tematosa (Aiton) Hassk) 72.815%; 20,500 mg/mL; 78.225%; 0.541 mg/mL. pasak bumi (Eurycoma longifolia Jack) 68.575%; 12,250 mg/mL; 53.930%; 0.383 mg/mL; and tigaron (Crataeva adansonii DC) 82.330%; 40,750 mg/mL; 75.395%; 0.609 mg/mL. The four phytochemical compounds have the potential as Covid-19 immunomodulators. This study concludes that the typical plant from Kalimantan that has been studied has the potential. This research can be continued by testing the effectiveness of phytochemicals as Covid-19 immunomodulators in experimental animals.
Anti-Fungal Activity Test of Sengkuang (Dracontomelon dao) Leaf Ethanol Extract on The Growth of Candida albicans Aima Insana
Tropical Health and Medical Research Vol. 4 No. 1 (2022): Tropical Health and Medical Research
Publisher : Baiman Bauntung Batuah Center

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35916/thmr.v4i1.63

Abstract

Candida albicans is an important opportunistic fungal pathogen that is responsible for the majority of fungal infections in humans. In healthy individuals, Candida colonizes mainly on the mucosal surfaces of the oral cavity, digestive tract, skin and genitals. Dracontomelon dao or known as Sengkuang has been used as a traditional medicine for various diseases. Based on various studies, Dracontomelon dao extract is reported to exhibit antimicrobial properties. This study aimed to analyze the antifungal activity of the ethanol extract of sengkuang (Dracontomelon dao) leaves on the growth of Candida albicans. The study used 96% ethanol extract by macerating the simplicia leaves of Dracontomelon dao originating from South Kalimantan, Indonesia. The antifungal activity was tested by well diffusion method at various concentrations of the test extract (10%, 20%, 30%, 40% and 50%). The results showed that the average diameter of the inhibition zones at concentrations of 10%, 20%, 30%, 40% 50% were 19.2 mm, 21.8 mm, 23.2 mm, 24.8 mm, 27 mm, respectively. Based on the results of the study, it was found that the ethanolic extract of sengkuang (Dracontomelon dao) leaves had antifungal properties against the growth of Candida albicans with the most effective concentration at a concentration of 50% with an average zone diameter of 27 mm. The content of phytochemical compounds from sengkuang leaf extract (Dracontomelon dao) are flavonoids, alkaloids, saponins, tannins, and triterpenoids. This secondary metabolite is thought to be able to inhibit the growth of the fungus Candida albicans. The ethanol extract of sengkuang leaves (Dracontomelon dao) has been shown to have antifungal activity in vitro so that it has the potential to be developed as an antifungal agent and can be a new solution in handling cases of Candida albicans infection.

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