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Hadi Barru Hakam Fajar Siddiq
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jifakfar@gmail.com
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Lembaga Penelitian dan Pengabdian Masyarakat Akademi Farmasi Jember. Jl. Pangandaran No. 42 Antirogo, Jember
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Jurnal Ilmiah Farmasi Akademi Farmasi Jember
Published by Akademi Farmasi Jember
ISSN : 25034707     EISSN : 2615756X     DOI : https://doi.org/10.53864/jifakfar
Core Subject : Health,
Medicine & Pharmacology
Jurnal Ilmiah Farmasi Akademi Farmasi Jember merupakan Jurnal yang menampung artikel ilmiah hasil penelitian di seluruh bidang Farmasi, seperti Farmasi Bahan Alam, Kimia Farmasi, Farmasetika, Farmasi Klinis, Farmasi Komunitas, dan bidang farmasi lainnya.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Pharmacology, Toxicology and Pharmaceutics (Lain-Lain)
Articles 4 Documents
 1 
Search results for , issue "2019: Juli - Vol.3 No.1" : 4 Documents clear
POTENSI STREPTOMYCES ENDOFIT RIMPANG KENCUR DAN DAUN SIRIH MERAH SEBAGAI ANTITUBERKULOSIS PADA MYCOBACTERIUM TUBERCULOSIS GALUR SENSITIF Siti Nur Azizah, Mikhania Cristiningtyas Eryani
JURNAL ILMIAH FARMASI AKADEMI FARMASI JEMBER 2019: Juli - Vol.3 No.1
Publisher : AKADEMI FARMASI JEMBER

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53864/jifakfar.v3i1.38

Abstract

The objective of this research was to obtain Endophitic Streptomyces from some medical plants which have antituberculosis effect and also to test its antitubercullosis activity againts sensitive stain of Mycobacterium tuberculosis. Medicinal plants used in this study were Kaemferia galanga, Hibiscus sabdariffa and Piper cronatum. Streptomyces was isolated using two different media namely Humic Acid Vitamin (HV) agar and HV with plant extract, and purified on Yeast Malt Agar (YMA) medium. Morphological characterization of Streptomyces obtained was observed including aerial mycelium and substrate mycelium, pigmentation, and colony surface. A total of 5 endophitic Streptomyces genus were obtained from medicinal plant. Isolates K.J3A, K.J3B, K.J4 and K.J11 from Kaemferia galanga radix, S.MJ1 from Piper cronatum folium. Streptomyces was not found from Hibiscus sabdariffa calyx. Each isolate had variety of characteristics which could be seen in aerial mass color, substrate mass color, and pigmentation. Antitubercullosis activity showed that total of 5 endophitic Streptomyces were not capable to inhibit the growth sensitive stain of M. tubercullosis.Keywods: Antituberculosis, endophitic actinomycetes, Kaemferia galanga, Hibiscus sabdariffa
PERBEDAAN KADAR PROTEIN PADA ASI DAN SUSU FORMULA BAYI USIA 0-6 BULAN Rizki Yuniarti, Hadi Barru Hakam Fajar Siddiq, Siti Nur Azizah
JURNAL ILMIAH FARMASI AKADEMI FARMASI JEMBER 2019: Juli - Vol.3 No.1
Publisher : AKADEMI FARMASI JEMBER

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53864/jifakfar.v3i1.39

Abstract

Protein is the main nutrient needed at the beginning of life, especially babies, but many things that cause the baby cannot be breastfed by his mother. The alternative is to give cow milk as a substitute for ASI. This study aims to determined the differences in protein levels and what protein levels were found in breast milk and formula cow's milk for children aged 0-6 months in Jember Regency. The kjehdahl method was selected, namely destruction, distillation, and titration to determined protein levels in breast milk and formula milk. From the results of the experiment, it was found that protein levels were 0.28%, 0.36% and 0.17% for formula A, B and ASI milk. The results of the SPSS analysis test using the T test showed a significance value of 0,189 (p0.05). These results indicate that there are no differences in the levels of protein contained in formula milk and breast milk.Keywords: breast milk, formula milk, protein content, kjehdahl method.
PENGARUH VARIASI KONSENTRASI HPMC SEBAGAI GELLING AGENT TERHADAP SIFAT FISIK GEL ANTIJAMUR EKSTRAK LENGKUAS (Alpinia galanga (L.) Swartz) Mikhania C.E., Agnis Pondinekaria Aditama, Sri Agita Ningrum
JURNAL ILMIAH FARMASI AKADEMI FARMASI JEMBER 2019: Juli - Vol.3 No.1
Publisher : AKADEMI FARMASI JEMBER

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (397.465 KB) | DOI: 10.53864/jifakfar.v3i1.36

Abstract

The aim of this research was to know the influence of HPMC variation concentration as gelling agent againts physical properties antifungal extract galangal gel (Alpinia galanga (L) Swartz). Pre-experimental the one shot case study was used as the research design. Gel is formulated into three formulas with various concentration of HPMC 2% (F1), 3% (F2), and 4% (F3). The materials used in this research were galangal extract, propylenglycol, glycerin, methyl paraben, and aquadest. The result showed that the variation concentration of HPMC give influence to physical properties of organoleptic gel (form, smell and colour), viscosity, and spreadibility of gel but did not influence homogeneity and pH of the gel.Keywords: gel, galangal extract, HPMC
POTENSI EKSTRAK KENCUR (Kaemferia galanga L.) SEBAGAI IMUNOMODULATOR PADA TIKUS MODEL YANG TERINFEKSI Mycobacterium tuberculosis Rosida, Kukuh Judy Handojo
JURNAL ILMIAH FARMASI AKADEMI FARMASI JEMBER 2019: Juli - Vol.3 No.1
Publisher : AKADEMI FARMASI JEMBER

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (158.753 KB) | DOI: 10.53864/jifakfar.v3i1.37

Abstract

Tuberculosis is an infectious disease caused by Mycobacterium tuberculosis. Tuberculosis can infect anyone in the patient's environment. Someone with good body immunity conditions will avoid tuberculosis. Increased immunity for tuberculosis sufferers is very important. The active substances contained in plants such as flavonoids and essential oils are important components in supporting the body's immunity. One plant that contains flavonoids and essential oils is kencur (Kaemferia galanga L.). This study aims to prove the potential of kencur extract as an immunomodulator in model rat infected with Mycobacterium tuberculosis. This study was a laboratory experiment using the kencur extract (EK) and samples of rats as a model. The sample used was 30 animals which were divided into 6 groups. Group 1 was a healthy animal (Normal). Groups 2, 3, 4 and 5 were treatment groups consisting of sick animals given placebo treatment (control), rifampicin (R), EK (Kencur Extract) and CRK (Mixture of Rifampicin and Kencur). Group 6 was a normal group given EK then infected with Mycobacterium tuberculosis (NK). Modeling was done by infecting experimental animals using Mycobacterium tuberculosis. The infection was 30 days and the treatment was 21 days. The parameters in this study were leukocytes and Laju Endap Darah (LED). The results of the kencur extract phytochemical screening study showed the presence of flavonoids. The results of the treatment showed that differences in the number of Leukocytes and LEDs between the control group and the treatment (sig 0.05). These results indicate that kencur extract has the potential as an immunomodulator.Keywords : Kaemferia galanga, Mycobacterium tuberculosis, imunomodulator

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