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Zahratul Aini
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JKKI : Jurnal Kedokteran dan Kesehatan Indonesia
Published by Universitas Islam Indonesia
ISSN : 20854145     EISSN : 25272950     DOI : 10.208885/JKKI.Vol10.Iss3.art5
Core Subject : Health,
Medicine & Pharmacology Public Health
JKKI: Jurnal Kedokteran dan Kesehatan Indonesia is a peer-reviewed journal in the field of medical and health sciences. This journal is designed as a place of dissemination of information and scientific knowledge, which publishes three times a year. It publishes original article, article review, and case report. These comprise of biomedical sciences, clinical medicine, public health sciences, and medical science education.
Arjuna Subject : Kedokteran - Kedokteran Keluarga
Articles 8 Documents
 1 
Search results for , issue "JKKI, Vol 7, No 4, (2016)" : 8 Documents clear
Recognize and prevent the transmission of virus zika Asri Hendrawati
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 7, No 4, (2016)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol7.Iss4.art1

Abstract

No Abstract
Analysis of independent active alert village in tridadi village, Sleman, D.I. Yogyakarta province Ferry Hendra Surya; Sunarto Sunarto
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 7, No 4, (2016)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol7.Iss4.art2

Abstract

Background : Active Alert Village Program has been started since 2006. The program was revitalized in order to accelerate the achievement of the Active Alert village in 2015. Its legal basis is the Decree of the Minister of Health No. 1529/Menkes/SK/X /2010 on General Guidelines for Development of Active Alert Villages. A study to evaluate this activity is needed. Objective : To determine the implementation and development of independent Active Alert Village in Tridadi Village, Sleman, DI Yogyakarta. Methods : This study was a descriptive study using case study design with qualitative analysis. Informants were determined by purposive method. Data collection was done using triangulation, which included non-participatory observation, in depth interview, as well as data and documentation of the alert village. Results : The implementation of active alert village in Tridadi had reached the stage of independence, where eight indicators of active alert village criterias had been met. This is due to the active participation of the village government, health cadres, social organizations, community leaders, and especially local residents themselves. Conclusion : Active alert village program in Tridadi has been implemented independently.
Complete resolution of right atrial free-floating thrombus after warfarin therapy in chemotherapy-induced cardiomyopathy: a case report Mirnawati Mappiare; Dian Pratiwi; Muzakkir Muzakkir
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 7, No 4, (2016)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol7.Iss4.art3

Abstract

Free-floating right heart thrombus is a rare phenomenon and has dismal rognosis. The optimal management of free-floating right thrombus remains controversial with no clear consensus. We present a case of right atrial free-floating thrombus in 56-year-old woman in chemotherapy inducedcardiomyopathy. Three weeks of warfarin treatment showed complete thrombus resolution. To the best of our knowledge, no such case has previously been reported in Indonesia.
The cytotoxic effect of pinostrobin fingerroot (boesenbergia pandurata)on the culture of hela cells Rosmelia Rosmelia; Betty Ekawati Suryaningsih; Hady Anshory; Yohanes Widodo Wirohadidjojo
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 7, No 4, (2016)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol7.Iss4.art4

Abstract

Background : Cancer is one of the leading causes of death worldwide, therefore struggles to find more effective treatment and prevention is needed. Several studies has been performed using natural ingredients, one of which is Temu Kunci (B. pandurata). Temu Kunci extract contains flavonoid pinostrobin that has been showed as having cytotoxicity effects. Cytotoxicity tests of pinostrobin have been performed on several tumor cell lines, but its cytotoxicity effect on HeLa cell line has never been reported. Objective : To assess cytotoxicity effect of pinostrobin temu kunci on HeLa cell culture Methods : This study used simple experimental design. Pinostrobin were isolated from temu kunci and proved by TLC densitometry compared to standard pinostrobin. HeLa cell culture were treated with pinostrobin with concentrations 5, 25, 50, 75, 100, and 250 ug/mL. Cytotoxicity test were performed by MTT assay. Data were analyzed using one-way ANOVA. Results : There was significant difference (p=0.000) of means of cell viability percentage, respectively: 92.58 ± 9.84 (5μg/mL), 91.78 ± 4.4 (25μg/mL), 80.09 ± 4.51 (50μg/mL), 76.89 ± 7.75 (75μg/mL), 67.85 ± 11.31 (100μg/mL), dan 48.82 ± 16.61 (250μg/mL). The IC50 was 250μg/mL. Conclusion : Pinostrobin showed no active cytotoxicity effect on HeLa cell culture.
The emotion regulation training to improve quality of life in patients with hypertension Kartika Mustafa; H.Fuad Nashori; Yulianti Dwi Astuti
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 7, No 4, (2016)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol7.Iss4.art5

Abstract

Background : Quality of life is an indicator of health. Quality of life is used to evaluate the physical and psychosocial effects of an illness suffered by a person, including a person’s knowledge and perception of the illness. In order to achieve optimal quality of life, patients with hypertension were reported frequent use defense mechanisms to repress emotions or regulate emotions. Objective : The aim of this study was to investigate the effect of emotion regulation training to improve the quality of life among patients with hypertension. The hypothesis of this study stated that there was an influence of emotion regulation training to quality of life among patients with hypertension. Methods : The quality of life was measured by using quality of life scale based on aspect from WHOQOL-BREF (1998). An experimental method used was a pre and post-test control group design. Data were analysed by using Mann Whitney U. Results : The researchers found that there was no difference in the level of quality of life between the experimental group and the control group were not given training. However, the results of this study indicate that the quality of life scores in the experimental group increased during follow-up (p=0,002 (p<0,05). This suggest that quality of life among experimental group has increased compared to the control group, and consequently it accepted the hypothesis. Conclusion : Emotion regulation strategies can helped a person to cope the life stress that can be associated with psychological distress and quality of life.
Role of oxidative stress on acute ischaemic stroke Ismail Setyopranoto
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 7, No 4, (2016)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol7.Iss4.art6

Abstract

After the onset of a stroke, blood flows disrupted in areas affected by vascular occlusion limit the delivery of oxygen and metabolic substrates to neurons causing ATP reduction and energy depletion. The glucose and oxygen deficit that occurs after severe vascular occlusion is the origin of the mechanisms that lead to cell death and cerebral injury caused of oxidative stress. Oxidative stress constitutes mechanism of injury of many types of disease processes. On oxidative stress occurs on the increase in ROS and RNS. This paper will discuss about cerebral ischemia that causes activation of ROS and RNS, also the mechanisms that play a role in cell death after cerebral ischemia, for example the role of phospholipase, Haber-Weiss reaction, and lipid peroxidation. It is also described about anti-oxidants to fight free radicals, for examples glutathione peroxidase, catalase and superoxide dismutase.
Interactive e-learning in pharmacology to enhance student competency in faculty of medicine UII Putrya Hawa
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 7, No 4, (2016)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol7.Iss4.art7

Abstract

Background : E-learning provides an opportunity for students to improve their knowledge by promoting self-directed learning. The aim of this e-learning is to encourage pharmacology active learning among undergraduate students in Faculty of Medicine UII. Objective : The aim of the study is to assess the effectiveness of the e-learning module in pharmacology, and the acceptability and student’s perception about the interactive e-learning module in pharmacology. Methods : This was an observational study, conducted on all medical student in Gastrointestinal module (Module 1) and Endocrine module (Module 2). Students were encouraged to register in website. By administrator approval, student can access to quiz. Another menus in the website after quiz are lectures, videos and semi-animated based CAL (computer assisted learning). Learning achievement were assessed based on module exam in pharmacology section. Feedback questionnaire were distributed to all medical student at the end of module. Results : The student’s access rate for e-learning module quiz in Module 1 is 100% and 35,48% in Module 2. In Module 1 about 75% questions have DMR value >75%. This value are increased than last year (54,5%) In Module 2, 30% questions have DMR value >75%. This value also increased than last year (0%). All students (100%) stated that e-learning in pharmacology modules are usefull. 78% stated that the website are informative and 74% admitted the material easy to access, 89,02% agreed that e-learning increase student’s motivation. Conclusion : Curriculum innovation as e-learning modules considerably was effective enhance student achivement in pharmacology. This innovation also well perceived among the student. All students agrreed that e-learning module were usefull.
Pandan leaves extract (Pandanus amaryllifolius Roxb) as a food preservative Resmi Aini; Ana Mardiyaningsih
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 7, No 4, (2016)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol7.Iss4.art8

Abstract

Background : Food poisoning or foodborne disease is still a serious concern in Indonesia. The use of harmful synthetic chemical preservatives are still widely found in society. Therefore, it would require efforts to develop safe natural preservatives― for instance, from Pandan leaves (Pandanus amayllifolius Roxb) which are often used as a natural food coloring and flavor concentrates, and has also widely known to have anti-bacterial activities. Objective : This study aims to determine the potential of pandan leaves extract (Pandanus amaryllifolius Roxb) in lowering the total plate count and the number of mold on traditional food. Methods : After making the water of pandan leaves extract, a phytochemical test was done to determine bioactive compounds, such as tannin, alkaloids, flavonoids, and polyphenols which has anti-microbial properties. In order to determine its food preservatives capabilities, Total Plate Count and Number of Mold was used on a traditional food called Putu Ayu. Results : Pandan leaves extract contain bioactive compound like tannin, alkaloids, flavonoids, and polyphenols. There were no colonization found in Putu Ayu that was added 15% pandan leaves extract concentration in 101 dilution. The result of Number of Mold Count of Putu Ayu that contain 15% pandan leaves extract concentration showed no mold growth in 104 dilution but failed to provide good fragarance and flavor in food products. Conclusion : Pandan leaves extract in the concentration of 15% were able to decrease Total Plate Count and Number of Mold in traditional food.

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