cover
Article Per Year (5 Year)
All
Home Page
OAI Link
Editorial Team
Contact
Reviewer
Google Scholar
Contact Name
Evy Yunihastuti
Contact Email
redaksi.jurnalpenyakitdalam@ui.ac.id
Phone
-
Journal Mail Official
redaksi.jurnalpenyakitdalam@ui.ac.id
Editorial Address
Departemen Ilmu Penyakit Dalam, FKUI/RSCM Jln Diponegoro No.71, Jakarta. 10430
Location
Kota depok,
Jawa barat
INDONESIA
Jurnal Penyakit Dalam Indonesia
Published by Universitas Indonesia
ISSN : 24068969     EISSN : 25490621     DOI : https://doi.org/10.7454/
Core Subject : Health,
Medicine & Pharmacology
Jurnal Penyakit Dalam Indonesia contains the publication of scientific papers that can fulfill the purpose of publishing this journal, which is to disseminate original articles, case reports, evidence-based case reports, and literature reviews in the field of internal medicine for internal medicine and general practitioners throughout Indonesia. Articles should provide new information, attract interest and be able to broaden practitioners insights in the field of internal medicine, as well as provide alternative solutions to problems, diagnosis, therapy, and prevention.
Arjuna Subject : Kedokteran - Kedokteran Internal
Articles 9 Documents
 1 
Search results for , issue "Vol. 4, No. 2" : 9 Documents clear
Factors Associated with Retention in Care One Year after Deliveryin Patients Undergoing Prevention of Mother to Child Transmission(PMTCT) at RSCM Yulidar, Yulidar; Yunihastuti, Evy; Djauzi, Samsuridjal; Padmita, Astrid Citra; Koesnoe, Sukamto
Jurnal Penyakit Dalam Indonesia Vol. 4, No. 2
Publisher : UI Scholars Hub

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Introduction. Retention in care is important to the successful of HIV treatment. This study is aimed to analyze factors associated with retention in care one year after delivery in patients undergoing PMTCT at HIV integrated clinic of RSCM. Methods. A retrospective cohort study was conducted among post-partum HIV patients who were given ARV therapy for PMTCT at HIV intergrated clinic of Cipto Mangunkusumo Hospital from January 2004 to May 2014. Evaluation of one year retention in care after PMTCT was performed by observing medical records of the patient. The collected data were factors associated with one year after delivery retention in care including age of patients, level of initial CD4, ARV toxicity, injecting drug user, duration of ARV before delivery, having child with positive HIV status, having spouse with positive HIV status, distance from the residence to the hospital, and indication of ARV. Bivariate analysis was performed by using Chi Square and Mann Whitney test and multivariate anaysis was performed by using logistic regression to assess factors associated with retention in car after PMTCT program. Results. 253 subjects met the inclusion criteria. In One year after delivery, the retention in care rate was 55,3%. Multivariate analysis found that factors significantly associated with one year retention in care were indication of ARV initiation for therapy (OR =3,812 [95% CI: 1,825-7,966]), non-IDU patients (OR=3,055 [95% CI: 1,382-6,752]), duration of ARV before delivery for more than 6 months (OR = 2,657 [95% CI: 1,328-5,316]), and level of initial CD4 less than 200/mm3 (OR = 2,033 [95% CI: 1,061-3,894]). Conclusions. Factors significantly associated with one year after delivery retention in care are indication of ARV for therapy, duration of ARV before delivery, non-IDU patients, and level of initial CD4 less than 200/mm3 . and Mann Whitney test and multivariate anaysis was performed by using logistic regression to assess factors associated with retention in car after PMTCT program. Results. 253 subjects met the inclusion criteria. In One year after delivery, the retention in care rate was 55,3%. Multivariate analysis found that factors significantly associated with one year retention in care were indication of ARV initiation for therapy (OR =3,812 [95% CI: 1,825-7,966]), non-IDU patients (OR=3,055 [95% CI: 1,382-6,752]), duration of ARV before delivery for more than 6 months (OR = 2,657 [95% CI: 1,328-5,316]), and level of initial CD4 less than 200/mm3 (OR = 2,033 [95% CI: 1,061-3,894]). Conclusions. Factors significantly associated with one year after delivery retention in care are indication of ARV for therapy, duration of ARV before delivery, non-IDU patients, and level of initial CD4 less than 200/mm3 .
Correlation between Disease Duration, Disease Activity Scoreand Disability Score with Diastolic Dysfunction in RheumatoidArthritis Women in Dr. Cipto Mangunkusumo Hospital Antono, Dono; Dhaki, Bernard Agus Sakti; Isbagio, Harry; Shatri, Hamzah
Jurnal Penyakit Dalam Indonesia Vol. 4, No. 2
Publisher : UI Scholars Hub

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Introduction. There are only few studies about correlation between non traditional risk factor and diastolic dysfunction in RA patients. This study aims to determinate the correlation between non traditional risk factors, including disease duration, disease activity and disability score with the diastolic dysfunction of women with RA. Methods. A cross-sectional, consecutive sampling study was conducted to 52 RA women without any previous cardiovascular disease history. All participants underwent an echocardiography to assess diastolic dysfunction and other findings associated. Duration of disease was assesed by direct interview, while the disease activity by calculating DAS28 and disability score by HAQ-DI. Results. Diastolic dysfunction was found in 30.8 % of study participants (13.5 % for each low and moderate grade, while severe was 3.8% ). Median duration of disease was 26.5 months (range 2-240), mean DAS28-CRP score was 2.69±1.11 while median DAS28-ESR score was 3.65 (range 1.13-7.5), and median HAQ-DI score was 0.29 (range 0-2.38). LV hypertrophy was found in 34.61% participants. Mean EF was 66.7±5.76%. Valve abnormality was found in 34.6% study participants. Correlation between duration of disease, DAS28-CRP, DAS28-ESR and HAQ-DI score with E/A in sequence was r= -0.065 (p=0.89), r=0.393 (p=0.38), r=0.357 (p=0.43), r=0.630 (p=0.12); while with E/E’ in sequence was r=0.136 (p=0.77), r= - 0.536 (p=0.21), r= - 0.393 (p=0.38), r=0.374 (p=0.41). Conclusions. Duration of the disease, disease activity score, and disability score in rheumatoid arthritis women had no correlation with diastolic dysfunction.
The Changes of Amino Terminal Pro B-type Natriuretic Peptide(NT-proBNP) Concentration and Left Ventricular EjectionFraction on Doxorubicin Chemotherapy Patients Kamelia, Telly; Waspadji, Sarwono; Makmun, Lukman Hakim; Effendi, Shufrie; Ramli, Muchlis; Timan, Ina Susanti
Jurnal Penyakit Dalam Indonesia Vol. 4, No. 2
Publisher : UI Scholars Hub

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Introduction. Cancer patients who received chemotherapy regimen containing doxorubicin has been known to have serious side effect in heart, called as cardiotoxicity. The measurement of NT-proBNP proposed to be used as a new parameter to identify and evaluate cardiotoxicity in cancer patients earlier before it has been manifested, superior than measurement of left ventricle ejection fraction (LVEF). The aims of this study to examine the changes of NT-proBNP concentration and LVEF on patients with cancer who receive chemotherapy regimen containing doxorubicin. Methods. The study used pre and post test design to observe the changes of NT-proBNP concentration and LVEF on the patients who receive naïve doxorubicin chemotherapy and after chemotherapy-cycle I to cyce IV at the Ciptomangunkusumo hospital, Jakarta. Echocardiography and NT-proBNP were examined on naïve chemotherapy and after chemotherapy each cycle. Statistical analysis was performed by using two way Anova and Friedman nonparametric test. Results. During the period of October 2007 to June 2008, a total of 29 consecutive patiets receiving doxorubicin chemotherapy regimen CHOP (Cyclophosphamide, doxorubicin, Vincristine, Prednisone and FAC-5 Fluorouracil, doxorubicin, Cyclophosphamide) were collected. The increase of median NT-proBNP concentration between naïve chemotherapy and: post chemotherapy cycle I was 32 pg/mL (12,5-124,6 pg/mL), post chemotherapy cycle II was 135 pg/mL (44-275,2 pg/mL), post chemotherapy cycle III was 275,1 pg/mL (97,8-907,2 pg/mL), post chemotherapy cycle IV was 514,6 pg/mL (80,6-6458,2 pg/mL). With Friedman test, p< 0,000. With Anova two way test, it was found the difference between naïve LVEF and LVEF: post chemotherapy cycle I was 5,1% (p 0,000), post chemotherapy cycle II 8,9% (p 0,000), post chemotherapy cycle III 11,2% (p 0,000), post chemotherapy cycle IV 12,5% (p 0,000). Conclusions. Elevated NT-proBNP concentration and LVEF reduction had been observed in doxorubicin chemotherapy patients.
The Association between Elevated Levels of Erythropoietin andEndothelial Progenitor Cell with Improvement of EndothelialFunction in Renal Failure Patients 3 Months after KidneyTransplantation Armelia, Linda; Susalit, Endang; HM, Maruhum Bonar; Shatri, Hamzah
Jurnal Penyakit Dalam Indonesia Vol. 4, No. 2
Publisher : UI Scholars Hub

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Introduction. Endothelial progenitor cell (EPC) is considered possible to reduce asymmetric dimethylarginine (ADMA) levels, which is a marker of improved endothelial function. However, clinically, there is still a debate about the role of EPC. This study was conducted to determine the correlation of elevated levels of erythropoietin (Epo) and the number of EPC CD34 + and CD133 + with improvement of endothelial function in renal failure patients 3 months after kidney transplantation. Methods. A cross-sectional study was conducted in prior and 3 months after kidney transplantation of renal failure patients who underwent a kidney transplant in Cipto Mangunkusumo hospital. The study included 21 subjects who enrolled from July 2013 to February 2014. Blood samples prior and 3 months after kidney transplantation were collected to evaluate the level of Epo, numbers of EPC CD34+ and CD133+ and level of assymetric dimethylarginine (ADMA). Statistical analysis was performed using Pearson or Spearman correlation test. Results. Results of this study showed that prior to kidney transplantation, level of Epo was increased but not statistically significant (p>0.05). The EPC numbers of CD34+ and CD133+ were significantly increased (p0.05). There was no association between the elevated level of Epo and the numbers of EPC CD34+ and CD133+ with the improvement of endothelial function three months after kidney transplantation. Conclusions. In three months after kidney transplantation, there is an elevated level of Epo, the numbers of EPC CD34+ and CD133+ and decrease level of ADMA. However, there was no association between the elevated level of Epo and the numbers of EPC CD34+ and CD133+ with the improvement of endothelial function in patients 3 months after kidney transplantation.
A 30 Years Old Woman with Sepsis, Skin and Soft TissueInfection, and Obesity Widinartasari, Franzeska ADM; Sodiq, Muhammad Ali; Sofro, Muchlis AU
Jurnal Penyakit Dalam Indonesia Vol. 4, No. 2
Publisher : UI Scholars Hub

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Obesity increases morbidity and mortality through its multiple efects on nearly every human system. Obesity has efect on the immune response which leads to susceptibility to infections. ß lactamases are bacterial enzymes that inactivate ß-lactam antibiotics by hydrolysis. One group of ß lactamases, extended-spectrum ß lactamases (ESBLs), have the ability to hydrolyse and cause resistance to various types of the newer ß-lactam antibiotics. The management of skin and soft tissue infection with polymicrobial infection and multi drug resistance can be challenging problem. We present a case of an obese patient with polymicrobial SSTI. bPatient showed clinical sign of sepsis with acute kidney injury. With fluid rescucitation, early antibiotic administration and surgical treatment, she gained clinical improvement. The key to successful management of patients with severe skin and soft tissue infection are early recognition and complete surgical debridement. Clinicians need to consider appropriate early empirical antibiotic combination therapy coverage or the use of combination therapy to treat SSTI
Diagnostic Approach and Treatment of Dieulafoy's lesion Saifuddin, Anshari; Renaldi, Kaka; Situmorang, Indah
Jurnal Penyakit Dalam Indonesia Vol. 4, No. 2
Publisher : UI Scholars Hub

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Dieulafoy’s lesion is a rare cause of upper gastrointestinal bleeding but become an important etiology. Pathogenesis of the disease evolved from earlier of its invention till now. It has been stated in recent study that the etiology of this disease is vary, from age to genetic. Size and arteriol configuration abnormality has been known as the main pathogenesis of the disease. Endoscopic procedure become the primary diagnostic tool, which effectiveness reached more than 90%. However, in some situation, it’s difficult to find the abnormality by endoscopic procedure. Hemostatic procedure via endoscopy is the main therapy of Dieulafoy’s lesion, which has been progressed from thermal coagulation, mechanical procedure, and epinephrine injection. The development of medical technology has made the better prognosis of the disease.
Risiko Kardiovaskuler pada Pasien Artritis Reumatoid Hidayat, Rudy
Jurnal Penyakit Dalam Indonesia Vol. 4, No. 2
Publisher : UI Scholars Hub

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Clinical Characteristic and Prevalence of Invasive Candidiasis Patient in Cipto Mangunkusumo Hospital Kalista, Kemal Fariz; Chen, Lie Khie; Wahyuningsih, Retno; Rumende, Cleopas Martin
Jurnal Penyakit Dalam Indonesia Vol. 4, No. 2
Publisher : UI Scholars Hub

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Introduction. Incidence of invasive fungal infections (IFI) are reportedly increasing in many countries. Candida is the most common cause of IFI. This study was conducted to determine the prevalence, clinical characteristics, and etiologic pathogen in adult patients with invasive candidiasis (IC) at Cipto Mangunkusumo Hhospital. Methods. This was a cross sectional study with restropective data collection fromof septic patients that’ medical records hospitalized in January 2012 until June 2014. Subjects were selected based on EORTC/MSG 2008 diagnostic criteria for IC. Demographic data, clinical and supporting data, diagnosis, etiologic pathogens, antibiotics, antifungal, outcome, and length of stay were recorded. Results. The IC prevalence at Cipto Mangunkusumo hospital was 12,3% (91 patients from total of 738 sepsis patients). Subjects consisted of 35 proven, 31 probable, and 25 possible invasive candidiasis patients. Candidemia was the most common form of IC and C. albicans was the most common etiologic pathogen. Mean age were 47,9 years, dominated with medical, non-neutropenic, and septic shock patient. Most patients had malignancy with lung infection. The most common medical intervention was urinary catheter. Most patients were given 3rd generation cephalosporin and the most common antifungal used was fluconazole. Forty four percent of IC patients did not get systemic antifungal treatment. Mortality rate was 64.8% and median length of stay were 27 days. Conclusions. IC prevalence was 12,3%. Mortality due to IC was high and C. albicans was the most common etiologic pathogen.
Validation of Rapid Emergency Medicine Score (REMS) in Predicting30 days Mortality in Elderly Visiting Emergency Department Rizka, Aulia; Harimurti, Kuntjoro; Pitoyo, Ceva W; Koesno, Soekamto
Jurnal Penyakit Dalam Indonesia Vol. 4, No. 2
Publisher : UI Scholars Hub

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Introduction. Rapid Emergency Medicine Score (REMS) has been known as a useful instrument to stratify patients in emergency department (ED) based on its ability to predict short term mortality. As the clinical characteristics of elderly patients visiting ED are frequently aypical, validation of REMS in this specific population is very important. To measure predictive validity of REMS in elderly patients visiting ED Methods. Prospective cohort study in elderly visiting ED of Cipto Mangunkusumo between September to October 2016. Subjects were followed for 30 days after visiting ED. Calibration (Hosmer Lemeshow test), discrimination (Area Under ROC Curve) and REMS predictive value of 30 days mortality were measured. Result. Of 321 elderly subjects visiting ED during study period, 306 subjects were included in the study. Among them, 163 (53,2%) were men. 30 days mortality incidence was 22,8% (95% CI 22,3-23,3). Median age was 68,3 (6,7) year. As many as 83 (27%) subjects were in red triage. There were 154 (50%) patients with REMS 0-7, 140 (46%) with REMS 8-17 and 12(4%) with REMS more than 17. Calibration plot shows r=0,23 with poor calibration (p=0,00) in Hosmer Lemeshow test. AUC of REMS in predicting 30 days mortality in elderly was 0,45 (95% CI 0,23-0,66). Conclusion. REMS shows poor calibration and discrimination in eldery patients visiting ED.

Page 1 of 1 | Total Record : 9

 1 

Filter by Year

2017 2017


Reset
Filter By Issues
All Issue Vol. 11, No. 2 Vol. 11, No. 1 Vol. 10, No. 4 Vol. 10, No. 3 Vol. 10, No. 2 Vol. 10, No. 1 Vol. 9, No. 4 Vol. 9, No. 3 Vol. 9, No. 2 Vol. 9, No. 1 Vol. 8, No. 4 Vol. 8, No. 3 Vol. 8, No. 2 Vol. 8, No. 1 Vol. 7, No. 4 Vol. 7, No. 3 Vol. 7, No. 2 Vol. 7, No. 1 Vol. 6, No. 4 Vol. 6, No. 3 Vol. 6, No. 2 Vol. 6, No. 1 Vol. 5, No. 4 Vol. 5, No. 3 Vol. 5, No. 2 Vol. 5, No. 1 Vol. 4, No. 4 Vol. 4, No. 3 Vol. 4, No. 2 Vol. 4, No. 1 Vol. 3, No. 4 Vol. 3, No. 3 Vol. 3, No. 2 Vol. 3, No. 1 Vol. 2, No. 4 Vol. 2, No. 3 Vol. 2, No. 2 Vol. 2, No. 1 Vol. 1, No. 2 Vol. 1, No. 1 More Issue