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INDONESIA
Indonesian Journal of Science and Pharmacy
Published by Pustaka Media Publishing
ISSN : -     EISSN : 30255244     DOI : -
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Chemistry Immunology & microbiology Medicine & Pharmacology
Indonesian Journal of Science and Pharmacy (IJSP) accepts scientific articles as original research articles, short communication, reviews, and mini-reviews from anyone without any discrimination, as long as they submit articles that meet scientific principles. Indonesian Journal of Science and Pharmacy publishes various scientific articles covering Science and Pharmacy, Pharmaceutical Sciences. The following are the field within the scope of Indonesian Journal of Science and Pharmacy: Chemistry, Biology, Pharmacology-Toxicology, Pharmacognosy-Phytochemistry, Pharmaceuticals, Analytical Pharmacy-Medicinal Chemistry, Natural Product Development, Management Pharmacy, Clinical-Community Pharmacy, Microbiology Pharmacy.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Pharmacology, Toxicology and Pharmaceutics (Lain-Lain)
Articles 4 Documents
 1 
Search results for , issue "Vol. 1 No. 3 (2024): Indonesian Journal of Science and Pharmacy" : 4 Documents clear
Characterization and Phytochemical Screening Of Tampala Bajakah Wood (Spatholobus littoralis Hassk) Extract With Methanol and Ethyl Acetate Solvents Liya Alviana; Ridwanto Ridwanto; Anny Sartika Daulay; Zulmai Rani
Indonesian Journal of Science and Pharmacy Vol. 1 No. 3 (2024): Indonesian Journal of Science and Pharmacy
Publisher : Pustaka Media Publishing

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Abstract

One of the plants that contains secondary metabolite compounds is Bajakah Tampala wood (Spatholobus littoralis Hassk). The aim of this research is to determine the chemical compounds contained in methanol and ethyl acetate extracts. The stages of this research include processing plant materials, making methanol and ethyl acetate extracts, characterization examinations, and phytochemical screening. Bajakah Tampala wood extract was made using the maceration method using methanol and ethyl acetate. The extract obtained was concentrated using a rotary evaporator. The characterization of Bajakah Tampala sawdust showed that the water content test was 2%, the water soluble juice content test was 7.1%, the ethanol soluble juice content test was 12.05%, the total ash content test was 3.65%. , and testing the ash content that is insoluble in acid was 0.1%. Meanwhile, the results of the phytochemical screening of Bajakah Tampala wood showed that it contained chemical compounds such as alkaloids, flavonoids, saponins, tannins, and steroids and triterpenoids.
Isolation of Chitosan from Lake Toba Freshwater Lobster Shells (Cherax quadricarinatus) Novita Yulianti Sinaga; Ridwanto Ridwanto; Anny Sartika Daulay; Haris Munandar Nasution
Indonesian Journal of Science and Pharmacy Vol. 1 No. 3 (2024): Indonesian Journal of Science and Pharmacy
Publisher : Pustaka Media Publishing

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Abstract

Chitosan is an amine polysaccharide that is formed after chitin undergoes a deacetylation process. This compound has a significant role as a natural biopolymer which is polycationic. This research aims to make chitosan from freshwater lobster shells obtained from Lake Toba. The research method is experimental. Includes making chitosan from freshwater lobster shells. The process of making chitosan includes demineralization, deproteination and deacetylation stages. Chitosan was characterized by measuring water content, ash content, yield, solubility, and analysis using an FTIR spectrophotometer. Based on the results of research that has been carried out, it was found that the characteristics of chitosan have a yield value of 50.88%, water content 5.9%, ash content 0.67% and chitosan dissolves in glacial acetic acid. The results of the research show that chitosan has similar functional groups to standard chitosan and the degree of deacetylation is 80.25%. This research has met the chitosan standard (SNI 7949:2013) with a percentage of the degree of deacetylation of chitosan that meets the standard (>60%).
Antibacterial Activity Of Freshwater Lobster Shells (Cherax quadricarinatus) Against Escherichia coli Putri Hafizha; Ridwanto Ridwanto; Anny Sartika Daulay; Haris Munandar Nasution
Indonesian Journal of Science and Pharmacy Vol. 1 No. 3 (2024): Indonesian Journal of Science and Pharmacy
Publisher : Pustaka Media Publishing

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Abstract

People still do not utilize freshwater lobster (Cherax quadricarinatus) shells optimally, even though the chitin compound contained in this waste can be modified into chitosan through chemical reactions. Chitosan obtained from freshwater lobster shells can be used as an antibacterial. This study aims to test the antibacterial activity of chitosan from freshwater lobster shell waste against Escherichia coli bacteria. Making chitosan is carried out through three processes, namely, demineralization, deproteination, and deacetylation stages. Then, characterization of the chitosan is carried out, which includes water content, ash content, yield, and solubility. The research results showed that the chitosan obtained in this study was 43.96%, and the degree of deacetylation value of freshwater lobster shell chitosan was 75.11%. Chitosan with a concentration of 0.3, 0.5, 0.7, and 0.9% provides an inhibition zone of 13.5, 15.9, 16.8, and 17.2 mm, respectively, against Escherichia coli. Thus, a concentration of 0.9% chitosan from freshwater lobster shells has better antibacterial activity and is categorized as having strong inhibitory power.
Isolation and Characterization of Chitosan from Kepah Shell Waste (Polymesoda erosa) Percut Sei Tuan, North Sumatera Dara Indah Sitorus; Ridwanto Ridwanto
Indonesian Journal of Science and Pharmacy Vol. 1 No. 3 (2024): Indonesian Journal of Science and Pharmacy
Publisher : Pustaka Media Publishing

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Abstract

Kepah clams (Polymesoda erosa) are one of the few aquatic animals that have a body and are protected by two cupped shells. Many people consume this shellfish meat, but many of the shells are thrown away by local people so that they only become waste. It is this shell waste that needs to be processed properly because it is known that shells are one of the fishery ingredients that contain chitin. One way to make kepah clams have a higher economic value is by isolating kepah clams into chitosan. The purpose of this study was to isolate and characterize chitosan from mussel shells and to determine functional groups using Fourier infrared (FTIR). The isolation methods used were deproteination, demineralization, depigmentation, deacetylation, and chitosan characterization. The results showed that the yield of the transformation of chitin into chitosan in cockles was 85.77% and had a brownish-white powder texture and no odor. The water content in the chitosan of the clam shells obtained was 1.53%, the ash content was 0.50%, and the degree of deacetylation obtained was 75%.

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