Medula
Medical Profession Journal of Lampung didirkan pada tahun 2013. Medula hadir memenuhi kebutuhan publikasi jurnal bagi mahasiswa Fakultas Kedokteran, Dosen ataupun klinisi dan profesi lain dibidang kedokteran. Medula diterbitkan dengan frekuensi 4 kali dalam setahun yang tiap nomornya mencakup 30 jenis artikel ilmiah seperti artikel penelitian, laporan kasus, tinjauan pustaka dan lain-lain. Medula sudah memiliki nomor ISSN media cetak sejak tahun 2013
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<![CDATA[Pengaruh Senam Kaki Diabetik terhadap Neuropati pada Pasien Diabetes Melitus ]]>
<![CDATA[Lutfia Qurotulnguyun]]>;
<![CDATA[Fidha Rahmayani]]>;
<![CDATA[Sutarto]]>
<![CDATA[ Medula Vol 13 No 1 (2023): Medula ]]>
Publisher : <![CDATA[CV. Jasa Sukses Abadi ]]>
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DOI: 10.53089/medula.v13i1.455
<![CDATA[The prevalence of people with diabetes mellitus has increased every year. Indonesia is ranked 7th in the world with 10.7 million people with diabetes. Diabetes in the long term can cause macrovascular and microvascular complications. One of the main complication of diabetes mellitus is diabetic neuropathy. Diabetic neuropathy is a microvascular complication that causes peripheral nerve dysfunction, which attacks the lower extremities, especially the legs. About 50% people with diabetes mellitus experience diabetic neuropathy. If not treated properly, this condition can reduce the patient's quality of life, increase the risk of amputation, and even death. Drugs are often the main choice for therapy, but cost constraints and side effects cause interest to look for other treatment alternatives. Treatment that can be done is to exercise. One of the recommended sports is diabetic foot exercise. Diabetic foot exercise is a light exercise focused on the legs consisting of ten steps. This sport can be done easily, does not cost money, and does not take a long time. Several studies state that diabetic foot exercises can be an alternative to prevent and inhibit the worsening of neuropathy in patients with diabetes mellitus by helping to accelerate peripheral blood circulation and strengthen muscles in the lower extremities to prevent injuries and foot deformities.]]>
<![CDATA[Identifikasi Bakteri Gram Negatif Penghasil Extended Spectrum Beta-Lactamase (ESBL) Pada Urin Pengguna Kateter di Ruang Rawat Inap Kelas III RSUD Dr. H Abdul Moeloek Bandar Lampung ]]>
<![CDATA[Revina Rifda Amelia]]>;
<![CDATA[Reyhan Anjani Putri]]>;
<![CDATA[Tri Umiana Soleha]]>
<![CDATA[ Medula Vol 13 No 1 (2023): Medula ]]>
Publisher : <![CDATA[CV. Jasa Sukses Abadi ]]>
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DOI: 10.53089/medula.v13i1.502
<![CDATA[Urinary catheterization is an action to insert a catheter into the patient's bladder through the urethra used in the hospital. The use of urinary catheters increases the risk of urinary tract infections (UTI) by about 5% every day. The incidence of nosocomial infection is 3 times higher in class III inpatients. According to research bacteria found as a cause of urinary tract infections due to urine catheters have a high enough potential to become a bacterium inhibiting Extended Spectrum Beta-Lactamase (ESBL). ESBL is a mutated β-lactamase enzyme, causing an increase in the enzymatic activity of β-lactamase, so that this enzyme can hydrolyze third generation sefalosporins and aztreonam. To find out the existence of ESBL-producing gram-negative bacteria in the catheter user urine in class III inpatients Dr. H. Abdul Moloek. This study used a categorical descriptive method with a cross sectional approach. The sample in this study were 22 patients who used catheters in class III inpatient rooms. Then the samples were tested for culture, biochemical tests and Double Disc Synergy Test. The results of a study of 22 patients undergoing a culture test found 4 patients with ESBL-producing gram-negative bacteria, 3 Escherichia coli bacteria (75%) and 1 Pseudomonas aeruginosa bacterium (25%) %), from these results the most bacteria producing ESBL is Escherichia coli. The conclusion is the highest amount of ESBL-producing bacteria was Escherichia coli (75%).]]>
<![CDATA[Penatalaksanaan Holistik Dermatitis Atopik Pada An. N Usia 12 Tahun Di Puskesmas Kota Karang Melalui Pendekatan Kedokteran Keluarga ]]>
<![CDATA[Kuntum Sureda]]>;
<![CDATA[Refi Fandana]]>;
<![CDATA[Sahab H. Sibuea]]>
<![CDATA[ Medula Vol 13 No 1 (2023): Medula ]]>
Publisher : <![CDATA[CV. Jasa Sukses Abadi ]]>
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DOI: 10.53089/medula.v13i1.534
<![CDATA[Atopic dermatitis also known as eczema is the most common form of chronic dermatitis. This disease is generally synonymous with itching which is characterized by dry skin, chronic lesions, and lichenification. Atopic dermatitis is believed to be associated with other forms of IgE disorders such as allergic rhinitis, asthma, and food intolerance. This disease results in a high rate of morbidity and its prevalence has increased in recent decades. The study conducted is a case report. Data were obtained through history taking and physical examination by conducting home visits. The assessment is carried out based on a qualitative diagnosis, process, and visit. Based on the examination, the patient was a 12 year old girl with atopic dermatitis. Knowledge of patients and families about the disease is very limited. Education and intervention provided to patients and families about atopic dermatitis and risk factors that can trigger the occurrence of this disease. On internal factors in cases such as genetic factors, age factors, and ignorance of the originator. External factors are the lack of family knowledge about atopic dermatitis, its complications and the environment that has many allergens. Pharmacological and non-pharmacological interventions are carried out in the form of education in preventing the onset of atopic dermatitis symptoms in patients. In the evaluation of increasing patient compliance to avoid risk factors and family knowledge about patient care. Services with a family medicine approach in pharmacological and non-pharmacological therapy are able to solve health problems and improve the patient's quality of life.]]>
<![CDATA[Faktor Risiko Kejadian Rinitis Alergi pada Anak ]]>
<![CDATA[Intan Nurhaliza Nurhaliza]]>;
<![CDATA[Mukhlis Imanto]]>
<![CDATA[ Medula Vol 13 No 1 (2023): Medula ]]>
Publisher : <![CDATA[CV. Jasa Sukses Abadi ]]>
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DOI: 10.53089/medula.v13i1.540
<![CDATA[Allergic rhinitis is one of the global health problems that affect about 400 million people in the world with prevalence of 8.38% in children and 14.93% in adolescents, in Indonesia the incidence of allergic rhinitis reaches 38%. Allergic rhinitis is a clinical symptom that occurs when the nasal mucous membrane is exposed to an allergen and induces an immune system-mediated inflammatory response. Allergic rhinitis can be triggered by several factors, including individual and environmental factors that can lead to resensitization and disease progression. The main risk factor for allergic rhinitis is family history of atopy, especially history of allergic rhinitis in both parents. The presence of atopic dermatitis, asthma, exposure to vehicle acids, cigarettes and house dust, obesity can be factors that increase the risk of allergic rhinitis in children. These risk factors have their respective mechanisms in increasing the risk of allergic rhinitis and have different levels of risk. Other factors such as gender and age did not contribute to increasing the risk of allergic rhinitis in children.]]>
<![CDATA[Usia Ibu Sebagai Faktor Risiko Terjadinya Plasenta Previa ]]>
<![CDATA[Salma Khairunnisa Hero]]>;
<![CDATA[Rodiani]]>;
<![CDATA[Giska Tri Putri]]>
<![CDATA[ Medula Vol 13 No 1 (2023): Medula ]]>
Publisher : <![CDATA[CV. Jasa Sukses Abadi ]]>
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DOI: 10.53089/medula.v13i1.554
<![CDATA[Placenta previa is complete or partial closure of the inner cervical ostium by the placenta. Placenta previa is one of the causes of postpartum hemorrhage and is a condition that can cause morbidity and mortality for both mother and baby. Placenta previa has the potential to become an emergency. Placenta previa is located in the lower uterine segment and causes obstruction of the cervix. This can make the vaginal birth process more difficult and risky, even leading to death from bleeding. There are several factors that can be risk factors for placenta previa, namely parity, history of curettage, cesarean section, previous history of placenta previa, multiple pregnancies, tumors, and age. At the age of <20 years the reproductive system is still immature. The endometrium in the immature uterine fundus causes the placenta to attach and grow in the lower uterine segment. At the age of> 35 years, the reproductive system has decreased, one of which is a decrease in blood flow to the uterus. So that the placenta will implant in the part that has more blood flow.]]>
<![CDATA[Pendekatan Diagnostik, Faktor Risiko, dan Tatalaksana Neuropati Diabetik ]]>
<![CDATA[Muhammad Labib MY Bima]]>;
<![CDATA[Fidha Rahmayani]]>;
<![CDATA[Hanna Mutiara]]>
<![CDATA[ Medula Vol 13 No 1 (2023): Medula ]]>
Publisher : <![CDATA[CV. Jasa Sukses Abadi ]]>
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DOI: 10.53089/medula.v13i1.555
<![CDATA[Diabetic neuropathy is the most common complication of diabetes mellitus. As many 25% of people with diabetes mellitus in the world and 54% in Indonesia suffer from diabetic neuropathy. Electro-diagnostic studies are best used for the diagnosis of diabetic neuropathy. In addition, the diagnosis can be made by scoring Diabetic Neuropathy Symptom (DNS) and Diabetic Neuropathy Examination (DNE). Patients with diabetes mellitus must pay attention to risk factors such as carbohydrate intake, physical activity, duration of suffering, and medication adherence to prevent complications of diabetic neuropathy. Management of diabetic neuropathy can be done with drugs or other supportive therapy. This article uses a literature review method from various national and international journal references with the following search keywords: prevalence, diagnosis, risk factors, and management of diabetic neuropathy.]]>
<![CDATA[The ROLE OF OBESITY IN BREAST CANCER METASTASIS ]]>
<![CDATA[Fadila Gustiani Daraz]]>;
<![CDATA[Indri Windarti]]>;
<![CDATA[Putu Ristyaning Ayu Sangging]]>
<![CDATA[ Medula Vol 13 No 1 (2023): Medula ]]>
Publisher : <![CDATA[CV. Jasa Sukses Abadi ]]>
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DOI: 10.53089/medula.v13i1.562
<![CDATA[Breast cancer is the most common type of cancer in women worldwide. One of the factors that are believed to have a role in the development and growth of breast cancer is nutritional status which can be associated with the body mass index of adult patients. It is estimated that overweight and obesity are risk factors for the spread of breast cancer to distant metastases. Mechanism of spread through two ways, estrogen and leptin. Aromatase is an enzyme in estrogen biosynthesis that promotes tumor growth through its expression in breast adipose stromal cells. Meanwhile, leptin is produced by adipocytes. Adipocytes that experience hypertrophy and hyperplasia cause pathophysiological changes that affect the development of breast cancer. Various case studies show that a diet high in fat and calories is associated with breast cancer. The high risk of obesity for breast cancer metastases. This is important to be studied further because of the large number of cases of breast cancer both globally, in Indonesia and in Lampung. This review article is important to know the relationship between obesity and breast cancer metastases, as scientific information and knowledge, and can be used as material for dietary intervention in obese breast cancer patients.]]>
<![CDATA[Merokok Sebagai Faktor Risiko Terjadinya Solusio Plasenta ]]>
<![CDATA[Sherly Melvinia Malia]]>;
<![CDATA[Nurul Islamy]]>;
<![CDATA[Ramadhan Triyandi]]>
<![CDATA[ Medula Vol 13 No 1 (2023): Medula ]]>
Publisher : <![CDATA[CV. Jasa Sukses Abadi ]]>
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DOI: 10.53089/medula.v13i1.564
<![CDATA[Placental abruption is the separation of the placenta before the time of delivery arrives. Placental abruption is one of the causes of bleeding during labor. Placental abruption is rare in vaginal delivery. In 1.000 births as many as 228 thousand mothers die. Bleeding is the highest cause of maternal death with a proportion of 27%. The most common causes of antepartum bleeding include placenta previa, placental abruption, and other causes such as marginal sinus bleeding, cervicitis, vasa previa, infection, and genital trauma. Placental abruption occurs when the mother's blood vessels detach from the placenta, this causes bleeding between the lining of the uterus and the placenta. There are various risk factors that can cause placental abruption, namely age, parity, alcohol consumption, cocaine consumption, and smoking. it can cause decreased blood flow to the placenta. This occurs due to changes in vasoactive substances such as prostacyclin and nitric oxide, or also due to endothelial cell damage. Nicotine in cigarettes also has a vasoconstrictive effect that can occur in the uterine arteries and umbilical arteries and increases the concentration of hemoxihemoglobin which interferes with oxygenation. The ensuing hypoxia causes microinfarction of the clotting placenta which gives rise to necrotic foci These necrotic foci then develop and cause placental abruption.]]>
<![CDATA[Hubungan Posisi Tidur dengan Tekanan Intra Okular pada Pasien Glaukoma ]]>
<![CDATA[Agatha Catherine]]>;
<![CDATA[Rodiani]]>;
<![CDATA[Risti graharti]]>
<![CDATA[ Medula Vol 13 No 1 (2023): Medula ]]>
Publisher : <![CDATA[CV. Jasa Sukses Abadi ]]>
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DOI: 10.53089/medula.v13i1.565
<![CDATA[Glaucoma still be the second most common cause of blindness in the world. Glaucoma is a group of neuropathic diseases of the optic nerve which is characterized by the extraction of the optic disc (cupping) may causes visual disturbances. Intraocular pressure (IOP) is the most influential factor of glaucoma and affected by various factors, especially body position during sleep. Sleep composed of REM sleep and NREM sleep is related to muscle tone and psychological activity that has impact for sleep posture. The increase of intraocular pressure is directly proportional to the increase of episcleral venous pressure. The increase of IOP in prone position is probably due to an increase in choroidal vascular volume and increase of episcleral venous pressure, whereas in the lateral decubitus position the increase in IOP is caused by compression of the jugular veins when using a pillow. IOP rises when move to the lateral decubitus position in the dependent eye was 1 mmHg and in the non-dependent eye was 2 mmHg. The angle of the head to the bed has an effect on increasing IOP, in the vertical head-down position there can be an increase of 70% due to the force of gravity, whereas in patients who sleep with their head at a higher angle to the mattress, the IOP will decrease compared to the horizontal sleeping position.]]>
<![CDATA[Analisis Korelasi Jumlah Trombosit dengan Nilai Mean Platelet Volume to Platelet Count Ratio (MPR) pada Pasien Covid-19 ]]>
<![CDATA[Putu Ristyaning Ayu]]>;
<![CDATA[Ridha Riano Fathunnisa]]>
<![CDATA[ Medula Vol 13 No 1 (2023): Medula ]]>
Publisher : <![CDATA[CV. Jasa Sukses Abadi ]]>
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DOI: 10.53089/medula.v13i1.567
<![CDATA[Coronavirus disease 2019 (Covid-19) is an infectious disease caused by SARS-CoV-2. The number of Covid-19 cases in Indonesia until November 2022 reached 6.7 million confirmed cases of Covid-19 and 160 thousand of them died. In treating Covid-19 patients quickly and accurately and reducing mortality from Covid-19, biomarkers are needed to predict patient mortality. Platelets, Mean Platelet Volume (MPV) and Mean Platelet Volume-To-Platelet Ratio (MPR) have been studied extensively and are thought to be used as predictors of the severity of Covid-19 patients. The design of this study was an observational analytic study with a cross-sectional approach which was carried out on 60 confirmed Covid-19 patients for the January-December 2021 period at Bandar Negara Husada Hospital. Based on the statistical analysis, the average platelet count was 260.5 and the MPR value was 0.04, and the results of the Pearson bivariate correlation analysis obtained r = 0.850 and p = 0.005. This study showed that there is a relationship between platelet count and MPR as a predictor of mortality and there is a difference between platelet count and MPR values in Covid-19 patients.]]>
