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Contact Name
Risti Graharti
Contact Email
risti.graharti@gmail.com
Phone
+6281369730011
Journal Mail Official
medulla.fkunila@gmail.com
Editorial Address
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Location
Kota bandar lampung,
Lampung
INDONESIA
Medula
Published by Universitas Lampung
ISSN : -     EISSN : 97726154     DOI : -
Medical Profession Journal of Lampung didirkan pada tahun 2013. Medula hadir memenuhi kebutuhan publikasi jurnal bagi mahasiswa Fakultas Kedokteran, Dosen ataupun klinisi dan profesi lain dibidang kedokteran. Medula diterbitkan dengan frekuensi 4 kali dalam setahun yang tiap nomornya mencakup 30 jenis artikel ilmiah seperti artikel penelitian, laporan kasus, tinjauan pustaka dan lain-lain. Medula sudah memiliki nomor ISSN media cetak sejak tahun 2013
Articles 250 Documents
Kurkumin dan Inflammatory Bowel Disease Stevani Febeline; Winda Trijayanthi Utama; Waluyo Rudiyanto
Medula Vol 11 No 4 (2021): Medula
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Abstract

Inflammatory Bowel Disease (IBD) is an inflammatory disease of the gastrointestinal tract. The exact cause of Inflammatory Bowel Disease is not yet known clearly. The diagnosis of inflammatory bowel disease is often delayed due to non-specific and intermittent symptoms. There are 2 types of IBD, namely Ulcerative Colitis and Crohn's Disease. Management of IBD can be done with drug therapy, surgery, or a combination of both. This therapy aims to reduce symptoms, improve quality of life, prevent disease recurrence and avoid complications. IBD treatment can occur over a long period of time, during which time it costs quite a bit and can cause various side effects that can be experienced by patients. Therefore, experts began to consider other alternative therapies that could be used, for example the use of curcumin compounds. Curcumin is the active pigment that gives turmeric its yellow color, a plant that belongs to the ginger family or Zingiberaceae and contains anti-inflammatory substances. The mechanism of action of curcumin is by suppressing activity of Nuclear Factor-Kappa B (NF-KB) and also plays a role in suppressing Interleukin-1 (IL-1), IL-6, IL-12, IL-17, and Tumor Necrosis Factor Alpha (TNF). -α), two major cytokines that play an important role in the regulation of the inflammatory response. Management of IBD can be done through the administration of drugs so that curcumin can be considered as one of the treatments for IBD.
Hubungan Keaktifan Berorganisasi dengan Manajemen Waktu dan Indeks Prestasi Kumulatif pada Mahasiswa Angkatan tahun 2013 di Fakultas Kedokteran Universitas Lampung Hendra Effendi; Rika Lisiswanti; Merry Indah Sari; Betta Kurniawan
Medula Vol 10 No 1 (2020): Medula
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Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v10i1.11

Abstract

Students have role as an agents of change by participating in organization without neglecting their academic achievement. Student’s academic achievement is measured by Grade Point Average (GPA). Students need a good skill to manage their time between academic activities, and organizational activities. We conduct research to determine the relationship of organizational participation with level of time management and GPA of students batch 2013 in Medical Faculy of Lampung University.This research method is a comparative and correlative analytic observational study with a cross-sectional approac. This research was conducted in June 2016 at the Faculty of Medicine, University of Lampung. The sample was selected by consecutive sampling and obtained 40 respondents for each student who was active and not active in organizing. The hypothesis test used was the Chi-square comparative test and the Gamma correlative test. The level of time management based on organizational participation showed no significant difference. There was a significant difference in the GPA based on the activeness of organizing with a better GPA on students who wereactive in organization. There was no relationship between the level of time management with the level of GPA.
Hubungan Antara Hipertensi dan Usia dengan Angka Kejadian Kanker Payudara Di RSUD Dr. H. Abdul Moeloek Bandar Lampung Tahun 2018 Mohamad Reihansyah Deswindra; Muhartono; Rizki Hanriko; Waluyo Rudiyanto
Medula Vol 10 No 1 (2020): Medula
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Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v10i1.12

Abstract

Breast cancer is one of the most highest incidence rate cancer in all countries. Age and Hypertension is known as risk factor for breast cancer. The purpose of this study is to know the relation between hypertension and age with breast cancer incidence rates in Dr. H. Abdul Moeloek Bandar Lampung. The method of this study is observational analytic study with case control design. The data that used are secondary data that gathered from medical records of patients in Dr. H. Abdul Moeloek Hospital and taken with consecutive sampling method. The data is analyzed using univariate and bivariate analysis using Chi-square test and Fisher test. The result is in the case group, hypertension percentage obtained was 12.5% ​​while those whose has not hypertension was 87.5%. In the control group the percentage of hypertension was 8.3% while those whose has not hypertension was 91.7%. In the case group ≥50 years of age percentage obtained was 54.2% while at age <50 years was 45.8%. In the control group ≥50 years of age percentage of 16.7% while at age <50 years at 83.3%. The results showed that age ≥50 years have a p value = 0,007 with OR = 5,909 and hypertension group have a p value = 0.500. The conclusion of this study is, there is no the relationship between hypertension and breast cancer incidence rates Lampung and there is relationship between the age of patients with breast cancer incidence rates in the Hospital of Dr. H. Abdul Moeloek Bandar Lampung.
G3P2A0 Hamil 30 Minggu Belum Inpartu dengan Partus Prematurus Imminens dan Riwayat Asma Kandita Mahran Nisa; Ratna Dewi PS
Medula Vol 10 No 1 (2020): Medula
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Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v10i1.14

Abstract

Imminent preterm is the presence of a threat in pregnancy with emergence signs in 20 weeks-37 weeks and the baby's birth weight is less than 2500 grams. Signs of diagnosis of imminent preterm such as contractions about 4 times in 20 minutes or 8 times in one hour and progressive changes in the cervix such as opening more than 1 cm, softening around 75-80% and even thinning of the cervix . Asthma is a chronic respiratory disorder that occurs due to breathing smooth muscle spasm, mucosal edema, and increased mucus secretion due to the response of allergens or excessive stimuli. Asthma in pregnancy is based on episodic symptoms in the form of airway flow obstruction, which is reversible or partially reversible. The severity of asthma can be classified as intermittent asthma, mild persistent asthma, moderate persistent asthma and severe persistent asthma, depending on the frequency and severity of symptoms, including night symptoms, episodes of attack and lung conditions. Some theories suggest the relationship of asthma with the occurrence of preterm labor. The theory is based on the similarity of the mechanism between the bronchial muscle and the myometrial muscle. Examples of theories proposed are the use of B-receptor stimulants that can relieve bronchospasm as well as can be used to delay preterm labor, such as the use of Salbutamol medication. In addition, Ca channel blockers that induce bronchodilation at the same time can also reduce uterine contraction activity. Prostaglandin F2α used in inducing labor can cause bronchoconstriction in subjects with a history of asthma and non-asthma.
Diagnosis dan Tatalaksana Stroke dengan Disfungsi Ereksi pada Pria Usia 50 Tahun Melalui Pendekatan Dokter Keluarga Vika Annisa Putri; Azelia Nusadewiarti
Medula Vol 10 No 1 (2020): Medula
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Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v10i1.15

Abstract

Stroke is a rapidly clinical signs of focal (or global) disturbance of cerebral function, with symptoms lasting 24 hours or longer or leading to death, with no cause other than of vascular origin. Stroke may cause disability and psychosocial disturbance. This study is a case report which aims to identify risk factors and clinical problems found in patients, and apply a holistic and comprehensive family doctor approach according to the problems found in patients, and conduct Evidence Based Medicine based management that is patient-centered and family focused. Primary data is obtained through history taking, physical examination and home visits. The result, Mr. UH, 50-years-old, complained left-sided limbs weakness since 2 years ago and also unable to get an erection. On the neurological clinical examination, we found parase of the left side of the limb, increase of left-sided physiological reflex, positive left-sided babinsky reflex, positive left-sided hoffman tromer, and left-sided facial nerve palsy. Uncontrolled hypertension and dyslipidemia causes stroke in these patients. In the psychosocial aspect, there is a lack of family knowledge about the patient's illness. Education and intervention are given to patients and families about stroke, prevention of other complications and treatment in 3 home visits. In the evaluation found an increase in patient compliance to avoid risk factors and family knowledge about patient care.
Hubungan Obesitas Sentral dengan Hitung Jenis Leukosit pada Laki-Laki Dewasa di Lingkungan Universitas Lampung Diva Iole Humaira; Khairun Nisa Berawi; Chicy WIdya Morfi
Medula Vol 10 No 1 (2020): Medula
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Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v10i1.16

Abstract

Obesity is a condition characterized by excessive accumulation of fat in the body. One form of obesity is central obesity which is characterized by the accumulation of fat, especially in the abdomen, and is more common in men. Central obesity has a stronger correlation with various diseases as a result of chronic inflammatory reactions that occur in adipose tissue. This ongoing inflammatory process will cause changes in various immunological parameters, one of which is leukocyte count. This study aims to determine the relationship between central obesity and leukocyte count in adult obese men. This research uses a cross-sectional approach. 59 study subjects were consisting of 39 central obese men and 20 non-obese central men. Venous blood samples were used in the calculation of differential counts and calculated Manually by microscope. The results showed a significant association between central obesity with neutrophil (p= 0,01), monocyte (p= 0,031) and lymphocyte counts (p= 0,003) but eosinophils and basophils did not have a significant relationship (p= 0,106 and p= 0,166). There is a relationship between central obesity with neutrophil type counts, monocytes, and lymphocytes in adult males with central obesity but eosinophils and basophils have no relationship.
Gejala Psikotik pada Pasien dengan Epilepsi Tidak Terkontrol Osy Lu’lu Alfarossi; High Boy Karmulrubog Hutasoit
Medula Vol 10 No 1 (2020): Medula
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Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v10i1.19

Abstract

Five until six percents patients with chronic uncontrolled epilepsy have shown with psychotic symptoms and increase eightfold risk for schizophrenia, especially temporal lobe epilepsy. Even the mechanisme still unknown, however family history, early onset epilepsy, and seizure type are the predictors of pshychotic in epilepsy. A 29-year-old man hospitalized after raged and destroyed neighbour’s house. The patient has history of uncontrolled epilepsy for 10 years and psychotics syndrome 1 year after the first seizure. In the psychiatricus status obtained dirty and untidy appearance, cooperative, dysphoric mood, flat affect, auditory, visual, and tactile hallucinations, paranoid delution, poor cognitive, and insight degree one. The multiaxial diagnosis with axis I: other determined mental disoder caused by brain damage and dysfunction and other illness, axis II: have not diagnose yet, axis III: idiopathic general epilepsy and epileptic syndrome, axis IV: economic, family, and social environment problems, and axis V: GAF 60-51. The patient treated with oral haloperidol 2x1,5 mg, oral tryhexiphenidil 2x2 mg, oral chlorpromazine 1x50 mg, oral phenitoin 1x100 mg, and oral depakote 1x250 mg. The patient got discharged after 21 days care with no auditory, visual, and tactile hallucinations.
Penatalaksaan Holistik Wanita 67 Tahun di Puskesmas Rawat Inap Gedong Tataan Dengan Osteoarthritis Genu dan Hipertensi Grade II Melalui Pendekatan Kedokteran Keluarga Deno Madasa Subing; Aila Karyus
Medula Vol 10 No 1 (2020): Medula
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Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v10i1.21

Abstract

Osteoarthritis and hypertension are diseases often attack elderly. Incidence of hypertension based on blood pressure carried out in the population aged> 18 years in Indonesia is around 34.1%. Lampung Province is ranked 16th out of 33 provinces with the incidence of hypertension around 22%. The incidence of Osteoarthritis in women in Indonesia is 12.7%. This study analysis is a case report. Primary data were obtained through history taking, physical examination and home visits. Secondary data were obtained from the patient's medical record. Assessment is based on a holistic diagnosis from the beginning, process, and end of study in a qualitative and quantitative manner.The 67-year-old Mrs. S, who has been diagnosed with Osteoarthritis and hypertension, has worries about her deteriorating health condition. Limitations of the patient's knowledge of the illness and bad lifestyle is a factor that causes problems that occur in patients and families.Holistic and comprehensive management of the patient's problems has been carried out by providing counseling to improve patient and family knowledge and providing a diet according to the patient's calorie needs.
Determinan Sosial Pasien Tuberkulosis Sebagai Faktor Resiko Penularan Tuberkulosis Riwayat Kontak Serumah di Wilayah Kerja Puskesmas Panjang dan Sukaraja Annas Fadhillah Bilqishti; Dyah Wulan Sumekar; T.A. Larasati
Medula Vol 10 No 1 (2020): Medula
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Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v10i1.22

Abstract

Pulmonary tuberculosis (TB) is transmitted through droplets. The possibility of TB infection is greater in groups close to patient, especially at home. Risk factors that influence TB are social determinants in the form of education level, employment, income and social class; The purpose of this study was to determine the effect of social determinants as risk factors for pulmonary TB transmission with a history of household contact. This research uses Case Control method. Case population was taken from smear TB patients (+) in July-December. Case and control samples were taken by respondents amounted of 30 people. Data analysis was performed by Chi Square test. Results The proportion of respondents from the case sample (53%) was male. For the control sample it was found (76%) that was also male. There was no relationship between education and household contact with TB (P = 0.605) work (P = 0.605), income ((P = 0.193), nor social class (0.111). Risk factors for household contact TB: Social determinants are not a risk factor for transmission of household contact tuberculosis
Hubungan Obesitas dengan Perubahan Perilaku pada Remaja di SMPN 4 Bandar Lampung Putri Giani Purnamasari; Khairun Nisa Berawi; Fitria Saftarina
Medula Vol 10 No 1 (2020): Medula
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Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v10i1.24

Abstract

Obesity (overweight) is a fundamental disease from non-communicable diseases such as diabetes, hypertension, and cardiovascular disease who still becomes a major health issue in Indonesia and the world. The teenager is a transition period that involves changes in physiological, psychological, social, and can develop into overweight or obesity. The fear of being obese is more common in girls than boys, and this explains why an effort to lose weight is mostly found in girls. This study aimed to determine the relationship between obesity and teenagers' behavioral changes in 14-16 years old of SMPN 4 Bandar Lampung students. It was a comparative analytic with a cross-sectional study. The sampling method used a case-control and using a questionnaire as a measuring tool. Data were then analyzed with a chi-square test. The study was conducted against 77 respondents with 48 respondents (62.3%) who were obese and 29 respondents (37.7%) not obese. While as many as 20 respondents (26.0%) had problematic behavior and 57 respondents (74.0%) did not have problematic behavior. The result of the chi-square test with a p-value was 0.015. There was a significant association between obesity with the teenager's behavior change in SMP Negeri 4 Bandar Lampung.

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