Garuda - Garba Rujukan Digital

Article Per Year (5 Year)

All

Pharmaciana: Jurnal Kefarmasian

PHARMACIANA
Website

Published by Universitas Ahmad Dahlan

ISSN : 20884559 EISSN : 24770256 DOI : 10.12928

Core Subject : Health,

Medicine & Pharmacology

Pharmaciana is a scientific journal published by the University of Ahmad Dahlan worked closely with Ikatan Apoteker Indonesia (IAI). Pharmaciana published three times a year, namely March, July and November. with ISSN 2088-4559 and e-ISSN 2477-0256. The article published in the Journal Pharmaciana selected by editors and reviewed by the reviewer. Articles published in Pharmaciana must not be published in other journals or have been previously published. Pharmaciana is indexed in google scholar, ACI (Asean Citation Index), Dimension (Crossreff), Garuda, Sinta, Sherpa Romeo, Index Copernicus International, DOAJ, and BASE. Pharmaciana is accredited by DIKTI (DGHE) of Indonesia No. 105/E/KPT/2022 April 07, 2022

Arjuna Subject : Kimia(semua kategori) - Kimia (Lain-Lain)

Articles 20 Documents

1 2

Search results for , issue "Vol 2, No 2 (2012): Pharmaciana" : 20 Documents clear

RESIDU PESTISIDA PIRETROID PADA BAWANG MERAH DI DESA SRIGADING KECAMATAN SANDEN KABUPATEN BANTUL Narwanti, Iin; Sugiharto, Eko; Anwar, Chairil
Pharmaciana Vol 2, No 2 (2012): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Pyrethroid pesticide residue in onion from Srigading Village, Sanden District,Bantul Regency has been investigated. The purpose of this study were to analyze,identificate and evaluate pyrethroid pesticide residues in onion. Onion sample wasextracted using homogenizer with acetone solvent. Clean-up was done usingchromatography column using florisil and determination of pesticide residue in thesamples was carried out by gas chromatography apparatus equipped with electroncapture detector (GC-ECD). The result showed that pesticide residues in onion samplein the range level: -cypermethrin (98.8-245.6 ppb) and -cyhalothrin (14.4-120.0ppb). The following pesticides have been detected in some of samples of onion analysed,but they have been detected above the Maximum Residue Limit (MRL).

FORMULASI VANISHING CREAM MINYAK ATSIRI RIMPANG JAHE (Zingiber officinale Roxb) DAN UJI AKTIVITAS REPELAN TERHADAP NYAMUK Aedes aegypti BETINA Ikhsanudin, Azis
Pharmaciana Vol 2, No 2 (2012): Pharmaciana
Publisher : Universitas Ahmad Dahlan

The essential oil of Ginger rhizome is a natural subtance which has been provedto have a repellent effect to the mosquito. The aim of this study was to know the effect ofthis subtance/these substances in vanishing cream dosage forms as repellant to thefemale Aedes aegypti mosquito. The essential oil of Ginger rhizome was isolated withaqueous vapor destillation. Then the result was determined for its physical properties,these were: viscosity, adhesivity, spreadibility and its repellant effect to mosquito aswell. The vanishing cream formulation, containing variation of the essential oilconcentration were prepared, these were: FI (formulation I), FII, FIII, FIV and FV,containing 6,25%, 12,5%, 15%, 20% and 25% of the essential oil respectivity. Eachformulas were tested for their physical properties were viscosity, adhesivity,spreadibility and its repellant effect to mosquito as well. The datas were analyzed.Statistically using SPSS version 16 with Kolmogorov-Smirnov and continued with thet-test (Mann-Whitney) (=0,05). The result showed that the duration of the adhesivityof FI was the longest than the others (1,37Â±0,15 minutes); the spreadibility of the FIwas widest (71,69Â±1,76 mm2), and the viscosity was the largert than others (27Â±0 cps).The repellant capasity of the FV was the longest than the others (47,3Â±1,80 minutes).

SINTESIS 4âHIDROKSIâ5âKLOROâ3âMETOKSIBENZALDEHID DAN ELUSIDASI STRUKTURNYA Warsi, Warsi; Sardjiman, Sardjiman; Riyanto, Sugeng
Pharmaciana Vol 2, No 2 (2012): Pharmaciana
Publisher : Universitas Ahmad Dahlan

The new compound have been synthesis with the chlorination reaction of vanillinwhich aims to produce vanillin chlorinated as raw material in the synthesis ofanalogues of curcumin with Cl substituents on the aromatic ring. The structure of thiscompound have been elucidated. Chlorination of vanillin performed using Cl2 gas,which produced by reaction of kaporit with concentrated hydrochloric acid. Thisreaction takes at temperature 35ÂºC for 30 minutes, with the AlCl3 as catalyst and THFas solvent. The purity of compound synthesized are determined by melting point andthin layer chromatography. The structure identification of the compound synthesizedconducted using spectrometry techniques, including UVâVis spectra, infrared spectra(cm-1, KBr) and Nuclear Magnetic resonance proton spectra (, ppm, DMSO-d6,1HâNMR, 500 MHz). Chlorination reaction of vanillin produced yellow crystal of 5chloroâ4âhydroxyâ3âmethoxybenzaldehyde, its melting point is 163.3 to 164.8ÂºC. Theaverage yield obtained of the this reseach is 40.54%.

PENGARUH UMUR DAN PENYAKIT PENYERTA TERHADAP RESIKO INFEKSI LUKA OPERASI PADA PASIEN BEDAH GASTROINTESTINAL Faridah, Imaniar Noor; Andayani, Tri Murti; Inayati, Inayati
Pharmaciana Vol 2, No 2 (2012): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Surgical Site Infection/SSI is the result of the contamination of bacteria whichenter the body during surgery. High risk of SSI is occured in gastrointestinal surgeryand influenced by the characteristics of the patients such as age and comorbidity sincethey deal with immunity system of the body. The research was aimed to identity theinfluence of age and comorbidity to the high risk of SSI in gastrointestinal surgerypatients. The research was a cross sectional research conducted prospectively at PKUMuhammadiyah Hospital Yogyakarta from January to March 2012. The researchsubjects were all inpatients undergoing gastrointestinal surgery, having visiblesurgical site and using antibiotic to prevent surgical site infection. There are 68patients in the research. Data that were analyzed comprised the characteristics ofpatients such as age and congenital disease to the risk of surgical site infection. Theresult of this research indicated that 2 patients (2,94%) suffering SSI. Based on the age,SSI happened to 2 patients in the age range of 41-60 years old. However, based on thestatistical result, there was no correlation between age and the existence of SSI(p>0.05). SSI also occured in 2 patients with comorbidity. However, there wascorrelation between the existence of comorbidity and SSI (p<0.05).

STUDI KAPASITAS ADSORPSI-REDUKSI ION Au(III) PADA ASAM HUMAT HASIL ISOLASI DARI TANAH GAMBUT RAWA PENING Prasasti, Dian; Juari, Sri; Sudiono, Sri
Pharmaciana Vol 2, No 2 (2012): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Isolation of peat soil humic acid and its application for adsorption-reduction ofAu(III) have been conducted. Humic acid was isolated from peat soil that was collectedfrom Rawa Pening, Central Java. Isolation of humic acid from peat soil was based onconventional alkaline extraction. Humic acid was extracted from peat soil with NaOH0.1 M, then precipitated with 0.1 M HCl, and purified with 0.1 M HCl/0.3 M HF 1/1.The isolated humic acid was characterized by FTIR spectroscopy, then applied foradsorption reduction of Au(III). Isothermic adsorption capacity on adsorptionreduction process of Au (III) also were studied. The gold metal formed was confirmedby XRD diffractogram, and photo optical microscope. The adsorption capacity withLangmuir isothermic model for humic acid was 192 mg/g. Peaks of gold particles in thedifractogram are 2 = 38, 44, and 64.

IDENTIFIKASI POTENSI INTERAKSI OBAT PADA PASIEN RAWAT INAP PENYAKIT DALAM DI RSUD Prof. Dr. MARGONO SOEKARJO PURWOKERTO DENGAN METODE OBSERVASIONAL RETROSPEKTIF PERIODE NOVEMBER 2009-JANUARI 2010 Sari, Andriana; Wahyono, Djoko; Raharjo, Budi
Pharmaciana Vol 2, No 2 (2012): Pharmaciana
Publisher : Universitas Ahmad Dahlan

The potensial drug interaction is potential action of a drug that changed orinfluced by other drugs concurrenly. Drug interactions are defined as a phenomenonthat occurs when the pharmacokinetic effect of a drug changes due to other drugdelivery. Drug interactions could cause advers drug reactions when the potential for apreviously unknown interaction. The purpose of this study is to identify potential druginteractions in patient hospitalized in the Prof. Dr. Margono Soekarjo PurwokertoHospital. The research method was an observasional retrospective study (November2009-January 2010) by using descriptive methods for the data analysis.The resultshowed that the potential drug interactions in the hospitalized patients in Prof. Dr.Margono Soekarjo Hospital is 56,76% (n= 259). Based on the significance categorieswhich proposed by Tatro (2006): a potential drug interaction with significancecategory 1 in ward patients in prof. Dr. Margono Soekarjo Hospital is 16,67%. Thedrug used thet known potential interaction, especially in the category of significance 1should be tailored to the patientâs need, risk and benefit, and have made efforts tooptimize it.

PENGHAMBATAN AKTIVITAS XANTHINE OXIDASE OLEH EKSTRAK ETANOL AKAR SAMBILOTO (Andrographis paniculata, Ness) SECARA IN VITRO Septianingsih, Ulfah; Susanti, Hari; Widyaningsih, Wahyu
Pharmaciana Vol 2, No 2 (2012): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Sambiloto root of which contained of flavonoids used by the people fortraditional medicine. In the previous publication, an effective xanthine oxidaseinhibitory activity of flavonoids was reported. In research, in vitro xanthine oxidaseinhibitory activity of etanolic root extract of Andrographis paniculata was determinedand Allopurinol was used as a control. The etanolic extract was succesively extractedin a Soxhlet with petroleum eter. Inhibition of xanthine oxidase by etanolic extract wasmeasured the decrease of uric acid production and monitored by spectrophotometer at295 nm with xanthine as substrat. The enzyme inhibitory activity was calculated, andthen IC50 was determined. The result of analyzed with Kruskal Wallis and MannWhitney at 95% confidental level . The flavonoids of etanolic extract were separated onusing by paper chromatography and the spot changing was determined using UV 366with and without amonia.The result of the research showed that the etanolic extract ofAndrographis paniculata inhibited xanthine oxidase activity with IC50 16,54 Âµg/mlwhile Allopurinol 4,29 Âµg/ml. The etanolic extract contained flavon or flavonol.

EVALUASI ADVERSE DRUG REACTION ANTIDIABETES BERDASARKAN ALGORITMA NARANJO DI BANGSAL RAWAT INAP RS PKU MUHAMMADIYAH YOGYAKARTA PERIODE DESEMBER 2011-JANUARI 2012 Fitriyani, Fitriyani; Supadmi, Woro
Pharmaciana Vol 2, No 2 (2012): Pharmaciana
Publisher : Universitas Ahmad Dahlan

This study is aimed to evaluated the antidiabetic adverse reaction using theNaranjo algorithm for diabetes mellitus patients in PKU Muhammadiyah HospitalYogyakarta for period December 2011-January 2012. This study used descriptivemethod. The data was collected from the medical record and interviews from patientswith diabetes mellitus who had used antidiabetic drugs after 3 days. The data wereanalyzed using the Naranjo algorithm. The results showed that during the periodDecember 2011-January 2012 there were 17 male patients and 14 female patients withdiabetes mellitus. The antidiabetic drugs that used to patients were metformin,metformin combined with glibenclamide, metformin combined with insulin, thecombination with insulin and insulin glimepirid. Then, the study showed that Naranjoalgorithm method was not suitable for evaluation the antidiabetic adverse reaction fordiabetes mellitus patients in PKU Muhammadiyah Hospital in Yogyakarta for periodDecember 2011-January 2012, because from 10 questions on the Naranjo algorithmthere were only 4 questions that could be answered. Its because there was not data toanswer questions. Research on the side effects cohort method should be done with theinterview and patient monitoring.

PENETAPAN KADAR ASAM BENZOAT DALAM BEBERAPA MERK DAGANG MINUMAN RINGAN SECARA SPEKTROFOTOMETRI ULTRAVIOLET Wati, Wahyu Irna; Guntarti, Any
Pharmaciana Vol 2, No 2 (2012): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Benzoic acid is one of the synthetic preservatives, work effectively at pH 2.5 to4.0, therefore it is widely used in acidic food or drink. This study aims to determinebenzoic acid content in some soft drink products, their conformity with Permenkes RINo.722/Menkes/Per/IX/88 on food additives, and to find out if there were any varianceof benzoid acid content in a different kinds of soft drink products.Determination of benzoid acid levels was performed by ultravioletspectrophotometry following solvent extraction of the benzoid acid with chloroform.Qualitatively, it was found that all of the sample contained benzoid acid. Quantitatively,the amount of benzoid acid in sample A was 227,73 mg/kg of materials; sample B was182,38 mg/kg of materials; sampel C was 259,52 mg/kg of materials; sample D was325,01 mg/kg of materials; sample E was 357,33 mg/kg of material. The resultindicated that there were variance of benzoid acid content in different soft drinkproducts. The use of benzoic acid in soft drinks was lower compaired to that ofPermenkes RI No.722/Menkes/Per/IX/88 (600 mg/kg of materials).

ISOLASI DAN AKTIVITAS LARVACIDA MINYAK ATSIRI AKAR (Curcuma mangga, Val.) TERHADAP LARVA Aedes Aegypti DAN PROFIL GC-MS NYA Lolita, Lolita
Pharmaciana Vol 2, No 2 (2012): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Curcuma mangga, Val. has been recognized as a traditional drug since a longtime ago. The active ingrediences of this plant especially the volatile oil containsmonoterpenes and sesquiterpenes. This research was aimed to study about thelarvacideâs activity of the volatile oil Curcuma mangga, Val. rhizome and also toanalyze its chemical compounds using the GC-MS. The volatile oil was isolated fromCurcuma mangga, Val. with steam and water distillation. The test method for larvicidewas done by dissolving the substances into water and added by Tween 20 10% v/v to thethe volatile oil. The concentration of the volatile oil of Curcuma mangga, Val. rhizomewere 100 ppm, 150 ppm, 200 ppm, 250 ppm, 300 ppm, and 350 ppm. The concentrationof positive control âabateâ were 0,01 ppm; 0,025 ppm; 0,05 ppm; 0,1 ppm; 0,5 ppmwhile as the negative control was Tween 20 solution. The perception time of larvaeâsmortality was 24 hours. The chemical compound of Curcuma mangga, Val. can beanalysed by the GC-MS. Data of larvaeâs mortality were used to estimate the values ofLC50 with the probit analyzis method. This study showed that the volatile oil of Curcumamangga, Val. have clear-brass colour, bitter taste, typically aromatic like mango,rendement equal to (1,23 Â± 0,029)% v/b and refractive index 1,4881. The value of LC50for the volatile oil of Curcuma mangga, Val. rhizome is (216,17 Â±12,51) ppm whileabate equal to (0,072 Â± 0,024) ppm. This finding indicates that abate were more potentto larvae of Aedes aegypti. The GC-MS showes 30 peaks chromatogram and six peakswhich indicates the possibility of alpha-pinene, camphene, beta-pinene, beta-myrcene,eukalyptole, ar-turmerone presence.

Page 1 of 2 | Total Record : 20

1 2

Filter by Year

2012 2012

Filter By Issues

All Issue Vol 14, No 1 (2024): Pharmaciana Vol 13, No 3 (2023): Pharmaciana Vol 13, No 2 (2023): Pharmaciana Vol 13, No 1 (2023): Pharmaciana Vol 12, No 3 (2022): Pharmaciana Vol 12, No 2 (2022): Pharmaciana Vol 12, No 1 (2022): Pharmaciana Vol 11, No 3 (2021): Pharmaciana Vol 11, No 2 (2021): Pharmaciana Vol 11, No 1 (2021): Pharmaciana Vol 10, No 3 (2020): Pharmaciana Vol 10, No 2 (2020): Pharmaciana Vol 10, No 1 (2020): Pharmaciana Vol 9, No 2 (2019): Pharmaciana Vol 9, No 1 (2019): Pharmaciana Vol 8, No 2 (2018): Pharmaciana Vol 8, No 2 (2018): Pharmaciana Vol 8, No 1 (2018): Pharmaciana Vol 8, No 1 (2018): Pharmaciana Vol 7, No 2 (2017): Pharmaciana Vol 7, No 2 (2017): Pharmaciana Vol 7, No 1 (2017): Pharmaciana Vol 7, No 1 (2017): Pharmaciana Vol 6, No 2 (2016): Pharmaciana Vol 6, No 2 (2016): Pharmaciana Vol 6, No 1 (2016): Pharmaciana Vol 6, No 1 (2016): Pharmaciana Vol 5, No 1 (2015): Pharmaciana Vol 5 No 1, 2015 Vol 5, No 2 (2015): Pharmaciana Vol 5, No 2 (2015): Pharmaciana Vol 5, No 1 (2015): Pharmaciana Vol 5, No 1 (2015): Pharmaciana Vol 4, No 2 (2014): Pharmaciana Vol 4, No 2 (2014): Pharmaciana Vol 4, No 1 (2014): Pharmaciana Vol 4, No 1 (2014): Pharmaciana Vol 3, No 2 (2013): Pharmaciana Vol 3, No 2 (2013): Pharmaciana Vol 3, No 1: Mei 2013 Vol 3, No 1 (2013): Pharmaciana Vol 3, No 1 (2013): Pharmaciana Vol 2, No 2 (2012): Pharmaciana Vol 2, No 2: November 2012 Vol 2, No 2 (2012): Pharmaciana Vol 2, No 1: Mei 2012 Vol 2, No 1 (2012): Pharmaciana Vol 2, No 1 (2012): Pharmaciana Vol 1, No 2: November 2011 Vol 1, No 2 (2011): Pharmaciana Vol 1, No 2 (2011): Pharmaciana Vol 1, No 1 (2011): Pharmaciana Vol 1, No 1: Mei 2011 Vol 1, No 1 (2011): Pharmaciana More Issue

Home Page

OAI Link

Editorial Team

Contact

Reviewer

Google Scholar

Contact Name
Muhammad Syahrir

Contact Email
m.syahrir7406@unm.ac.id

Phone
-

Journal Mail Official
nurkhasanah@pharm.uad.ac.id

Editorial Address
Jl. Prof. Dr. Soepomo, S.H., Janturan, Warungboto, Umbulharjo, Yogyakarta, Indonesia Kode pos 55164

Location
Kota yogyakarta,

Daerah istimewa yogyakarta

INDONESIA

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Home Page

OAI Link

Editorial Team

Contact

Reviewer

Google Scholar

Contact Name Muhammad Syahrir

Contact Email m.syahrir7406@unm.ac.id

Phone -

Journal Mail Official nurkhasanah@pharm.uad.ac.id

Editorial Address Jl. Prof. Dr. Soepomo, S.H., Janturan, Warungboto, Umbulharjo, Yogyakarta, Indonesia Kode pos 55164

Location Kota yogyakarta, Daerah istimewa yogyakarta INDONESIA

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Contact Name
Muhammad Syahrir

Contact Email
m.syahrir7406@unm.ac.id

Phone
-

Journal Mail Official
nurkhasanah@pharm.uad.ac.id

Editorial Address
Jl. Prof. Dr. Soepomo, S.H., Janturan, Warungboto, Umbulharjo, Yogyakarta, Indonesia Kode pos 55164

Location
Kota yogyakarta,

Daerah istimewa yogyakarta

INDONESIA