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Current Biochemistry Journal
Published by Institut Pertanian Bogor
ISSN : 23557877     EISSN : 23557931     DOI : -
Core Subject : Science, Education,
Biochemistry, Genetics & Molecular Biology Education
Current Biochemistry (CB) publishes the results of original research that contribute significantly to the understanding of the chemical compound and reaction that occur within living organism. Preference will be accorded to manuscripts that develop new concepts or experimantal approaches, particularly in the advancing areas of biochemistry science. Manuscripts that are primarily theoretical in nature or in the field of bioinformatics must be directed toward explaining important results previously not understood, making important predictions that can be experimentally tested, or developing segnificant advances in theory of general interest to biochemists. Submission of manuscripts in emerging areas in biochemistry, chemical biology, biophysics, proteomics, model studies and structures, cellular and molecular biology, computational biochemistry, biotechnology, and new methods development is encouraged especially if they address basic biochemical mechanisms.
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Articles 4 Documents
 1 
Search results for , issue "Vol. 3 No. 3 (2016)" : 4 Documents clear
Effect of Boiled Cassava Leaves (Manihot esculenta Crantz) on Total Phenolic, Flavonoid and its Antioxidant Activity Hasim Hasim; Syamsul Falah; Lia Kusuma Dewi
Current Biochemistry Vol. 3 No. 3 (2016)
Publisher : IPB University

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Abstract

Cassava leaves (Manihot esculenta Crantz) widely used as vegetables in many regions. Cassava leaves contain many minerals such as Fe, Zn, Mn, Cu, Mg, Ca, P, K, S, contain crude protein, β-carotene and have an active compound of flavonoids, phenolic, and contain chlorophyll which is a natural antioxidant. The aims of this study were to analyze the effect of boiled cassava leaves on total phenolics, flavonoids, and its antioxidant activity. Cassava leaves extraction was done by maceration method to obtain the methanol extract and infundation method to get the water extract. Based on phytochemical test, cassava leaves contained alkaloids, flavonoids, phenolic, tannins, and saponins. The highest levels of total phenolics and flavonoids contained in the methanol extract of simplicia, 30.57 mg GAE/g and 881.33 mg RE/g, respectively. Cassava leaves extract had potential as an antioxidant with the highest inhibition of DPPH radicals produced by the methanol extract of simplicia with IC50 values of 92.10 mg/L and followed by methanol extract of boiled leaves, water extract of simplicia, and water extract of boiled leaves with IC50 144.28, 155.76 dan 170.71 mg/L , respectively. In conclusion, the process of boiling cassava leaves could reduce total phenolic, total flavonoids and antioxidant activcity.
Uji Fitokimia dan Identifikasi Senyawa-Senyawa Metabolit Sekunder Ekstrak Etil Asetat, Etanol dan Air Tanaman Zingiber zerumbet Asal Pulau Timor Origenes Boy Kapitan; Laksmi Ambarsari; Syamsul Falah
Current Biochemistry Vol. 3 No. 3 (2016)
Publisher : IPB University

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Abstract

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Toxicity Extract and Faction of Surian Toona sinensis Leaf and Bark against Shrimp Larvae Artemia salina L. Rori Theresia; Syamsul Falah; Mega Safithri; Muhammad Assyar
Current Biochemistry Vol. 3 No. 3 (2016)
Publisher : IPB University

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Abstract

Surian (Toona sinensis) is one of the herbs that contain many bioactive compounds. Part of surian plants that can be utilized as therapy is leaf and bark. This study aims to determine the toxicity of leaf and bark extract of Surian through Bhrine Shrimp Lethality Test (BSLT), then compare toxic concentration of water extract, and ethanol 70 %, and n-hexane, diethyl ether and ethyl acetate fractions to shrimp larvae (Artemia salina L). The results showed that water content of leaves simplicia was 8.08 % and bark was 6.26 %. The highest extract rendement value by ethanol solvent was 23 %. The result of BSLT test probit analysis showed that the extract of ethyl acetate bark fraction had the highest toxicity with LC50 value 405.641 ppm, while leaf water extract had the lowest toxicity with LC50 value 707.787 ppm.
The Usage of Momordica charantia as Face Cleansing Cosmetics: Momordica charantia Leaves Extract as Absorbent of Heavy Metal, Surface Tension Reducer and Skin Antibacterial Dimas Andrianto; Popi Asri Kurniatin; Silvy Aulya; Dewi Eriyanti
Current Biochemistry Vol. 3 No. 3 (2016)
Publisher : IPB University

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Abstract

Momordica charantia (daun pare in Indonesian) is one of Indonesian herbal plants which useful property has not been explored. M. charantia contains chemical substances such as oil and saponin. Nowadays, the society possesses a high awareness regarding the risk of using artificial chemicals for skin care and more people are switching to use herbal cosmetics. The extract of M. charantiahas been proven to be able to be used as one of the active components of herbal based facial cleansing cosmetics. Its active properties include its ability to absorb heavy metal from air pollution and motor vehicles emission, decrease surface tension, and to act as an antibacterial agent.In the research, M.charantia was extracted using 4 (four) solvents, namely water, ethanol, methanol, and hexane. The research then examined the property of each extract in metal absorption (using Atomic Absorption Spectrophotometry / AAS), decreasing surface tension, and antibacterial activities. The result of the test showed that the water based extract was the most effective extract in reducing surface tension and in inhibiting the development of Escherichia coli and Staphylococcus aureus bacteria, while the ethanol based extract was the most effective one in absorption of Pb and Hg metals and in inhibiting the development of Staphylococcus epidermidis bacteria. The result indicated that M. charantiaextract has the potentials to be used as facial cleanser and can also counter the bacterial infection which could cause acnes.

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