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Berkala Ilmu Kesehatan Kulit dan Kelamin

BIKK
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Published by Universitas Airlangga

ISSN : 19784279 EISSN : 25494082 DOI : 10.20473

Core Subject : Health, Science,

Immunology & microbiology Public Health

Arjuna Subject : -

Articles 12 Documents

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Search results for , issue "Vol. 28 No. 2 (2016): AGUSTUS" : 12 Documents clear

Relationship between Diet and Acne Kristina Sihaloho; Diah Mira Indramaya
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 28 No. 2 (2016): AGUSTUS
Publisher : Faculty of Medicine, Universitas Airlangga

Background: Acne is a disorder of pilosebasea unit, that mostly affect an adolesecent, caused by hormonal changing. Dietary is one factor that was thought to induce acne. But the association between diet and acne are still controversial. Purpose: Review the role of some diets for acne Review: Acne is multifactorial disease, whereas diet is one of many factors that excarcerbate acne. Some dietaries are thought have some roles in acne, including carbohidrate, milk, chocolate, fatty acid, zinc-iodine, vitamin A, and antioxidant. Some research has proved the relationship between diets and acne but there are still few limitations. Conclusion: Relationship between diets and acne still need more research with better methods. Key words: acne, diet, glicemic index.

A Retrospective Study: Incidence and Management of Genodermatoses Dwi Ratna Adisty; Iskandar Zulkarnain
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 28 No. 2 (2016): AGUSTUS
Publisher : Faculty of Medicine, Universitas Airlangga

Background: Genodermatoses are rare congenital diseases of the skin especially genetically determined. Genodermatoses can be grouped into three categories: chromosomal, single gene, and multifactorial. Skin condition in the genodermatoses patients not only important to start the right therapy but also to detect the other system diorders including malignancy. Objective: To evaluate the incidence of genodermatoses and to know the management of each patients. Methods: A retrospective study of genodermatoses patients in Kemuning Ward Dr. Soetomo Hospital Surabaya in 5 years period 2010-2014. Results: The incidence of genodermatoses among patients in Kemuning Ward was 10 of 1912 (0.52%).They are five males and five females (1:1). This study had shown that the diagnosis of genodermatoses were ichthyosis in 3 patients, epidermolysis bullosa (EB), and xeroderma pigmentosum (XP) each in 2 patients, neurofibromatosis (NF) type 1 in 1 patient, lymphangioma circumscriptum in 1 patient, and verrucous epidermal nevi in 1 patient. Positive family history of the same disease was obtained in one patients with xeroderma pigmentosum. No data of consanguinity found in ten patients. Conclusion: Small number of patients with genodermatoses due to the small incidence of the disease. The management vary depends on the clinical manifestations observed in each patient. Key words: genodermatoses, incidence, management, retrospective.

Haemorrhagic Bullous Lesion in Henoch-Schonlein Purpura Renata Prameswari; Diah Mira Indramaya; Sawitri Sawitri
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 28 No. 2 (2016): AGUSTUS
Publisher : Faculty of Medicine, Universitas Airlangga

Background: Henoch-Schonlein purpura (HSP) is a vasculitis of the small vessels and the most common type of vasculitis in children. Vesicles and haemorrhagic bullae were thought to be rare in HSP and maybe difficult to diagnose. Purpose: To describe the rare case of haemorrhagic bullous lesion in HSP. Case: A 15-year-old Javanese girl was admitted to Dr. Soetomo General Hospital Surabaya with one week history of multiple haemorrhagic blisters on her extremities, accompanied with joint pain, abdominal pain, and severe nausea. Firstly, it’s only a few redness patches then become numerous and changed to haemorrhagic blisters. A dermatological examination shown multiple bullae and vesicles on multiple palpable erythematous purpura. There were hypokalemia on laboratory examination and histopathological examination concluded a leukocytoclastic vasculitis. Discussion: Fluid balance, oral corticosteroid, oral antihistamine, antiemetic injection, and potassium correction were administered to the patient. Dexamethasone was discontinued because there was a presence of melena. Symptomatic treatment was given and significantly improvement was achieved in one month after treatment. Conclusion: Henoch-Schonlein purpura is diagnosed based on history, physical, clinical, and histopathological examination. Vesicles and haemorrhagic bullae are rare in HSP, and it does not seem to have any prognosis value in the outcome of HSP. Key words: Henoch-Schonlein purpura, haemorrhagic bullous lesion, small vessel vasculitis.

Characteristic of Tinea Cruris and/or Tinea Corporis in Ciamis District Hospital, West Java Wulan Yuwita; Lies Marlysa Ramali; Risa Miliawati N. H.
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 28 No. 2 (2016): AGUSTUS
Publisher : Faculty of Medicine, Universitas Airlangga

Background: Tinea cruris and/or corporis is one of the most common dermatophytosis in the world, which is still being a health problem in Indonesia. Purpose: The purpose of this study was to find out the characteristic of tinea cruris and/or tinea corporis in Ciamis District Hospital, West Java. Methods: The design was descriptive cross-sectional study, with consecutive sampling methods. The subjects of the study were patients with tinea cruris and/tinea corporis who visited Dermatovenereology Clinic in Ciamis District Hospital, West Java. Data was collected from the history taking, physical examination, microscopic examination from skin scraping using 10% potassium hydroxide solution (KOH), and fungal culture, until 40 patients with positive result of dermatophyte culture were included. The study was conducted from 2015, 1st August to 15th October. Results: Tinea cruris and/or corporis were most commonly found in female (52.5%), age 45-64 years. Duration of illness £1 month (20/40), recurrence(7/40), the source of infection was anthropophylic (10/40), with clinical manifestations were erythematous and hyperpygmented macules and papules, scales, with central clearing (36/40). The most commonly isolated dermatophytes were Trichophyton rubrum (95.8%) followed by Epidermophyton floccosum (4.2%). Conclusion: The most frequent dermatophytes species causing tinea cruris and/or corporis in Ciamis District Hospital, West Java are T. rubrum followed by E. floccosum with minimal inflammation clinical manifestation and source of infection was antropophilic. Key words: tinea cruris, tinea corporis, Ciamis District Hospital.

C-Reactive Protein in Various Degrees Severity of Psoriasis Vulgaris Lita Setyowatie; Hari Sukanto; Dwi Murtiastutik
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 28 No. 2 (2016): AGUSTUS
Publisher : Faculty of Medicine, Universitas Airlangga

Background: Psoriasis vulgaris is an inflammatory, chronic, recurrent, and, non-contangious skin disease. The severity grade of psoriasis is measured with psoriasis area and severity index (PASI) score. C-reactive protein (CRP) is a sensitive, but not specific indicator of inflammation. In the active stage of psoriasis, highly increased CRP levels were found, whereas at remission they present a decrease level. Purpose: To evaluate the profile of CRP level in psoriasis vulgaris patients with various degress of psoriasis vulgaris severity in Dr. Soetomo Hospital Surabaya. Methods: Blood samples were collected in 16 patients to measure the CRP level in psoriasis vulgaris patients with various degrees of severity. Results: There were 16 patients (10 male and 6 female) with various degrees of psoriasis vulgaris severity (5 patients with mild severity, 8 patients with moderate severity, and 3 patients with severe severity). All CRP results were within normal limits. Conclusion: Many factors can influence the CRP levels, CRP can not be as single indicator of inflammation in psoriasis vulgaris. Key words: psoriasis vulgaris, c-reactive protein, PASI score.

The Use of Thalidomide in Steroid Dependent Continous Erythema Nodosum Leprosum Leprosy Patient: A Case Report Dian Pertiwi Habibie; M Yulianto Listiawan
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 28 No. 2 (2016): AGUSTUS
Publisher : Faculty of Medicine, Universitas Airlangga

Background: Treatment thalidomide in erythema nodosum leprosum (ENL), can inhibits the transcription repression mediated by tumor necroting factor (TNF). Thalidomide can be used as sparing agents drug to reduce the dependency of steroid. Purpose: To report the effectiveness of thalidomide to treat ENL and of relinquish steroid dependency. Case: A 39 years old patient with leprosy borderline lepromatous type, came with complain bumps on skin accompanied with fever, occurring recurrently since 4 years ago if the steroid’s dose tappered off. He consumed steroid routinely every day for the last 4 years and if the dose was tapered to 4 mg once daily, the painful bumps reappeared often accompanied by fever. Thalidomide 50 mg twice daily and methyl prednisolone 4 mg once daily was given. The constant tapering off of methyl prednisolone done every week. After a month, the patient shown significant improvement. Discussion: Thalidomide is effective in ENL, it is regarded as first line in terms of clinical efficiency because it displays an effect on 90% of ENL patients. In this case, thalidomide was given and steroid dose was reduced slowly while observing the clinical manifestation and patient’s complain. There were no complain of recurrent ENL after discontinuation of steroid and thalidomide, no serious adverse event happened in this patient as well. Conclusion: The effectiveness of thalidomide in ENL is primarily due to its action on TNF but other mechanisms may contribute to its anti-inflammatory effect. Thalidomide is effective in the management of steroid dependent ENL patient. Key words: thalidomide, steroid dependent, methyl prednisolone, erythema nodosum leprosum

A Retrospective Study: The Profile of New Patient with Vitiligo Nurina Dhani Rahmayanti; Rahmadewi Rahmadewi
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 28 No. 2 (2016): AGUSTUS
Publisher : Faculty of Medicine, Universitas Airlangga

Background: Vitiligo occurs worldwide, with prevalence of 0.1 to 2.0 percent, commonly begins in childhood or young adulthood, with peak onset of 10 to 30 years, but it may occur at any age. Based on vitiligo new patient profile, treatment and recovery of patients could be expected to be better. Purpose: To evaluate the profile of new patients with vitiligo. Methods: A restrospective descriptive study was carried out in Medical Cosmetic Division Dermatovenereology Outpatient Clinic Soetomo Hospital Surabaya in 2012-2014. Result: New patient of vitiligo in Medical Cosmetic Division Dermatology and Venereology Out Patient Clinic Soetomo Hospital Surabaya in 2012-2014 were 188, which was 0.2% of total patient. The most frequent age was 25-44 years old as much as 61 patients, and mostly woman (68.1%). Fourty three point one percent came to out patient clinic after having vitiligo for more than 12 months. 78.5% had multiple lesions and 83.5% with lesion less than 10 cm2. Topical corticosteroid were given to 86.2%, sun block in 84%, topical oksoralen in 48.9% and cosmetic camouflage in 10.6% patient. Most of them (69.5%) never came to out patient clinic to check their disease. Conclusion: The average of vitiligo case in Soetomo Hospital Surabaya is 62 patient per year and mostly woman Key words: vitiligo, retrospective, profile.

Serum Level of Vitamin D (25[OH]D) in Patient with Atopic Dermatitis Meidyta Sinantryana Widyaswari; Iskandar Zulkarnain; Diah Mira Indramaya
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 28 No. 2 (2016): AGUSTUS
Publisher : Faculty of Medicine, Universitas Airlangga

Background: Atopic Dermatitis (AD) is a chronic inflammatory relapsing skin disorder along with itchy sensation. Etiopathogenesis DA remains unclear, however in common are caused by impaired epidermal barrier function of the skin and immune system that tend to ensue infection. Vitamin D is an immunomodulator and plays an important role in the pathogenesis of DA through improving the integrity of skin barrier permeability, expression of antimicrobial peptide (AMP), which inhibit infection, and reduce inflammation. Deficiency of vitamin D may increase the development risk of DA lesion. Purpose: To evaluate the serum levels of vitamin D (25[OH]D) in patients with DA. Methods: A descriptive observational cross-sectional study, in 34 DA patients at Dermatology and Venereology Outpatient Clinic of Dr. Soetomo Hospital Surabaya. Subjects were enrolled through consecutive sampling, serum vitamin D levels were measured using enzyme-linked immunosorbent assay (ELISA) method. Results: Serum levels of vitamin D (25[OH]D) in DA patients was 22.72±14.55 ng/mL. Serum levels of vitamin D based on the severity DA: mild (30.86±22.66 ng/mL); moderate (20.42±10.13 ng/mL); and severe (18.84±8.22 ng/mL). Conclusion: Deficiency of vitamin D can occur in DA patient with low level of serum vitamin D (25[OH]D), but the relationship with the severity of DA remains to be done further research. Key words: atopic dermatitis, vitamin D (25[OH]D).

A Retrospective Study: Erysipelas and Cellulitis Patients’ Profile Amalia Rositawati; Sawitri Sawitri
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 28 No. 2 (2016): AGUSTUS
Publisher : Faculty of Medicine, Universitas Airlangga

Background: Erysipelas and cellulitis are acute infectious diseases caused by Streptococcus pyogenes/haemolytic and Staphylococcus aureus, which attack the subcutaneous tissue and superficial areas (dermis and epidermis). In the course of the disease, erysipelas and cellulitis often fall in a serious condition that requires proper handling. Purpose: To determine a general overview as well as predictive factors of the severity of erysipelas and cellulitis condition. Methods: Retrospective study by evaluating medical records of erysipelas and cellulitis patients in Medical Ward of Dermatology, Dr. Soetomo General Hospital Surabaya from the period of 2012-2014. Results: The incidence of new cellulitis patients during 2012-2014 were 29 cases (67.4%) while erysipelas 14 cases (32.6%). Most of chief complaint were the form of swelling, redness, and pain sensation. The most common of prodromal symptoms were febris, precipitating factors largely due to scratching and stab wounds. Most underlying disease of both erysipelas and cellulitis was anemia. Predilection was common in the lower extremities in erysipelas (92.8%) and cellulitis (93.1%). Normal count of leukocytes in patients with erysipelas was 52.9% and 56.25% in patients with cellulitis. Culture examination was perfomed in 33 (76.74%) of the total 43 cases. Ampicillin injection therapy was commonly used in 22 patients (51.1%). Conclusion: The correct management could increase the recovery rate, prevent complication and recurrency of erysipelas and cellulitis. Key words: cellulitis, erysipelas, Streptococcus pyogenes/haemoliticus, Staphylococcus aureus.

Open Oral Food Challenge in Adult with Food Allergy to Chicken Meat Yosi Charly; Cita Rosita SP; Trisniartami Setyaningrum
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 28 No. 2 (2016): AGUSTUS
Publisher : Faculty of Medicine, Universitas Airlangga

Background: Food allergy is a hypersensitivity of the body's response to food. Food allergies are divided into three groups: immunoglobulin E (IgE) mediated, non-IgE mediated, and mixed IgE mediated with non-IgE mediated. Food allergies can be life threatening, causing malnutrition, eating disorders, and psychosocial problems. The gold standard for the diagnosis of food allergy is double-blind placebo-controlled food challenge (DBPCFC), but time consuming, costly, and a resuming specialist to perform it. Open oral food challenge (OFC), commonly used as screening in the clinic, with food suspected of being in its true form, in particular to look for symptoms. Objective: To evaluate specific IgE and open OFC in adult patients with a history of food allergies to chicken. Methods: Descriptive cross-sectional study involving 28 adult patients with history of food allergies to chicken were diagnosed as urticaria, angioedema, and atopic dermatitis. Specific IgE chicken meat was performed and patients were asked to eliminate chicken for 1 week before open OFC. Results: Twenty eight samples, specific IgE within normal limit. Positive results of open OFC were found in 9 people and 19 negative result. Conclusion: The specific IgE chicken does not always correlate with clinical reactivity and open the OFC can be used for the diagnosis of food allergy to chicken meat. Key words: food allergies, spesific Ig E, open oral food challenge.

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