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Medula

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Published by Universitas Halu Oleo

ISSN : 23391006 EISSN : 24430218 DOI : http://dx.doi.org/10.33772/medula

Core Subject : Health, Science,

Biochemistry, Genetics & Molecular Biology Immunology & microbiology Medicine & Pharmacology Nursing Public Health

MEDULA mengundang kontribusi bagi penelitian original dan fundamental pada bidang kesehatan sebagai sebuah artikel yang melewati proses review.

Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)

Articles 7 Documents

Search results for , issue "Vol 4, No 2 (2017)" : 7 Documents clear

Hubungan Infeksi Torch Pada Kehamilan Dengan Kejadian Kelainan Kongenital Pada Bayi Baru Lahir Zida Maulina Aini; Juminten Saimin
MEDULA JURNAL ILMIAH FAKULLTAS KEDOKTERAN UNIVERSITAS HALU OLEO Vol 4, No 2 (2017)
Publisher : Halu Oleo University

ABSTRACT Introduction: TORCH infection in pregnancy in Indonesia shows a high prevalence, ranging from 5.5% to 84%. The results showed that from 100 samples of pregnant women who had an infection, one of TORCH was found to have 12% of children with congenital abnormalities, 70% had abortion and 18% had Intra Uterine Fetal Death (IUFD). TORCH infection has not received serious attention in pregnant women in Southeast Sulawesi. Methods: The design of this study used cross-sectional studies. The research was conducted in RS Ibu and Anak Permata Bunda and RS dr.Ismoyo Kendari from 2013-2016. Sample examination of TORCH infection include IgG Toxoplasma, IgG Rubella, and IgG Cytomegalovirus. The results of the examination are TORCH infection (IgG Toxo, IgG Rubella, IgG CMV) and observation of pregnant mother until newborn. Bivariate analysis was done to see the relationship between independent variable and dependent using statistical test odds ratio (OR) 2x2 contigency table with 95% confidence level (α = 0,05). Result: Subjects of this research were 33 people by total technique Sampling. Results examination of TORCH infection are obtained: IgG Toxoplasma (+), IgG Rubella (+), IgG CMV (+), IgG Toxoplasma (+) IgG Rubella (+), IgG Toxoplasma (+) IgG CMV (+), IgG Rubella (+) IgG CMV (+), and IgG Toxoplasma (+) IgG Rubella (+) IgG CMV (+). The most frequent result of TORCH infection was IgG Toxoplasma (+) IgG Rubella (+) IgG CMV (+) of 11 samples (33.3%). Based on the obeservation of pregnant women to childbirth, there were 12 samples (36,4%), Abortus 8 samples (24,2%), congenital abnormalities 7 samples (21,2%), Intra Uterine Fetal Death (IUFD) 4 samples (12.1%), and Blighted Ovum (BO) of 2 samples (12.1%). Based on result of data analysis with Chi-Square statistical test to correlation of TORCH infection with congenital incidence in newborn p value was 0,092 (p> 0,05). These results suggest that TORCH infection is not associated with the incidence of congenital abnormalities in newborns. Conclusion: Based on this research, it was found that there was no correlation between TORCH infection in pregnancy with incidence of congenital abnormality (P = 0,092, p> 0,05). Some of the high yields of TORCH IgG titers have a baby aterm output. While the value of IgG titer that is not too high have abortus output, IUFD and congenital abnormalities. Keyword: TORCH, IgG, Congenital Disorders

Uji Aktivitas Antibakteri Ekstrak Etanol Bawang Putih (Allium sativum) terhadap Pertumbuhan Bakteri Salmonella typhii dan Shigella dysenteriae Gyidian Upa; Agusalim Ali; Yenti Purnamasari
MEDULA JURNAL ILMIAH FAKULLTAS KEDOKTERAN UNIVERSITAS HALU OLEO Vol 4, No 2 (2017)
Publisher : Halu Oleo University

ABSTRACT Diseases of gastrointestinal infections, especially those caused by the bacterium Salmonella typhii and Shigella dysenteriae still a health problem in Indonesia. Garlic (Allium sativum) is a traditional medicine which has antibacterial properties. Garlic contains Allisin, alkaloids, tannins and saponins. The purpose of this study was to determine the antibacterial activity of ethanol extract of the bulbs of garlic (Allium sativum) on the growth of the bacteria Salmonella typhii and Shigella dysenteriae. This study is experimental with post test only control group design. Test of inhibition is determined based on the diameter of clear zone formed. Testing was performed against a pure extract of garlic, the positive control, negative control and solvent control for comparison. Each treatment is performed three times. The results showed that the ethanol extract of garlic (Allium sativum) does not produce a clear zone well against Salmonella typhi and Shigella dysenteriae, it can be concluded that the ethanol extract of garlic (Allium sativum) has no antibacterial activity against Salmonella typhii and Shigella dysenteriae. It is recommended to use another method to extract further research as the development or continuation of this research Keywords: Antibacterial activity, garlic(Allium sativum), Salmonella typhi, Shigella dysenteriae.

Analisis Faktor-Faktor Risiko Kejadian Katarak di Daerah Pesisir Kendari Alfi Laila; Ilyas Raupong; Juminten Saimin
MEDULA JURNAL ILMIAH FAKULLTAS KEDOKTERAN UNIVERSITAS HALU OLEO Vol 4, No 2 (2017)
Publisher : Halu Oleo University

ABSTRACTBackground:Cataract is a condition where lens that usually clear and transparent become cloudy. Based on the last report, cataract is responsible for 51% of blindness that happen in the world, which presented around 20 millions people. In Indonesia, the estimate of incindent rate of cataract is 0.1% a year which means every year there is one person a new patient of cataract among 1000 people. The occurrence of cataract cannot be separated from the risk factors that affect it. Purposes:This research aims to determine the risk factor of the occurrence of cataract in costal area of kendari. Methods:This research is observational analytic research with case-control matching design. The population were all patients who visited the Puskesmas Abeli, Nambo dan Mata in 2015-2016. The sampling method is purposive sampling with the cases are those patient who was diagnosed with cataract and the control are not. The samples are 62 people with the comparison cases and controls is 1:1 so that the number of cases-samples are 31 people and controls-samples are 31 people who had been matched such as age and gender. The instrument of this research is questionnaire. Data were analyzed by determining the odds ratio. Results:The result of this research showed that job, income, and education are a risk factor for the occurrence of cataract which have meaningful statistically. Smoking habit and drink alcohol are a risk factor for the occurrence of cataract which doesn’t have meaningful statistically. The result of bivariat test for job is OR:2.908(CI95%:1.031-8.204), income OR:3.067 (CI95%:1.053-8.934), education OR:3.431 (OR95%:1.100-10.704), smoking OR:1.816 (IC95%: 0.616-5.355) and alcohol OR:2.467 (IC95%:0.733-8.369) Conclusions:The conclusions of this research is that job, income and education is a meaningful risk factor for the occurrence of cataract. Smoking and alcohol is a meaningless risk factor in costal area of Kendari. Keywords: cataract, risk factor

Hubungan Indeks Massa Tubuh dengan Kadar Kolesterol Total pada Staf dan Guru SMA Negeri 1 Kendari Nur Rahma Musadalifa; Satrio Wicaksono; Tien Tien
MEDULA JURNAL ILMIAH FAKULLTAS KEDOKTERAN UNIVERSITAS HALU OLEO Vol 4, No 2 (2017)
Publisher : Halu Oleo University

ABSTRACT Background:The nutritional status of adults can be monitored by using the body mass index of nutritional status especially that associated with excess weight and less weight. Overweight can also affect cholesterol levels in the body which is one of the most important factors for determining a person's risk of developing cardiovasculardisease. Research Purposes: The purpose of this research is to know the relationship between body mass index with total cholesterol levels of staff and teachers at SMAN 1 Kendari.Research Methods:This research was an analytic observational study with cross-sectional design. The study population was the entire staff and teachers of SMAN 1 Kendari as many as 103 people. The method used in sampling was total sampling. The number of samples were 51 people. This research was conducted with the approval of spread sheets and questionnaires, measuring height and weight, then measures the total cholesterol level. Data were analyzed using Pearson correlation test. It was considered significant at p value ≤0,05. Research result:The results obtained of this research were the staff and teachers who had a unnormal body mass index as much as 42 respondents (82.3%) and who had normal body mass index by 9 respondents (17.6%). Total cholesterol levels in the staff and teachers gained as much as 20 respondents had normal cholesterol levels (39.2%), as many as 20 respondents had a slightly high cholesterol (39.2%), and as many as 11 respondents had highest cholesterol was (21.6% ). Based on statistical test found that there was a significant relationship between body mass index with total cholesterol (p = 0.001).Conclusion: The Conclusions from this research was there were relationship between body mass index with total cholesterol levels of staff and teachers at SMAN 1 Kendari.Keywords: Body mass index, total cholesterol levels, staff and teachers SMAN 1 Kendari.

Analisis Faktor Risiko Obesitas dan Hipertensi dengan Kejadian Diabetes Melitus Tipe 2 di Rumah Sakit Umum Daerah Kota Kendari Asmarani Asmarani; Andi Cahaya Tahir; Anisa Adryani
MEDULA JURNAL ILMIAH FAKULLTAS KEDOKTERAN UNIVERSITAS HALU OLEO Vol 4, No 2 (2017)
Publisher : Halu Oleo University

ABSTRACTBackground:Type-2 Diabetes Mellitus is one type of diabetes that is the highest rates of incidence. Type-2 DM is a metabolic disorder with a characteristics of chronic hyperglycemia that occurs due to insulin resistance or lack of insulin secretion. Based on basic medical research showed that prevalence of type-2 DM in Indonesia keep on Increasing. Increasing cases of diabetes are theoretically cannot be separated from the risk factors that affect it. Purposes:This research aims to determine whether obesity and hypertension is a risk factor in the occurrence of type-2 DM. Methods:This research is observational analytic research with case-control matching design. The population were all patients who visited the RSUD Kota Kendari in September-December 2016. The sampling method is purposive sampling with the cases are those patient who was diagnosed with type-2 DM and the control are not. The samples are 136 people with the comparison cases and controls is 1:1 so that the number of cases-samples are 68 people and controls-samples are 68 people who had been matched such as age and gender. The instrument of this research are the weight-scales and microtoice to assess the nutritional status with calculation of BMI and also stethoscope and sphygmomanometer to measure the blood pressure. Data were analyzed by determining the odds ratio. Data was considered significant if UL and LL does not include the value of 1. Result:The results of this research showed that obesity and hypertension are a risk factor for the occurrence of type-2 DM with the results of statistical tests of obesity obtained OR : 7,164., CI 95% : 3,365-15,250 and hypertension obtained OR : 4,166., CI 95% : 2,026-8,567. Conclusion: The conclusions of this research is that obesity and hypertension are a risk factor in the incidence of type-2 DM in RSUD Kota Kendari in 2016.Keywords: Type-2 Diabetes Mellitus, Obesity, Hypertension

Hubungan Kadar Timbal dalam Darah terhadap Kejadian Hipertensi pada Operator SPBU di Kota Kendari Noviarsih Muslimah; Hartati Hartati; Fedelia Raya
MEDULA JURNAL ILMIAH FAKULLTAS KEDOKTERAN UNIVERSITAS HALU OLEO Vol 4, No 2 (2017)
Publisher : Halu Oleo University

ABSTRACTHypertension is a common health problem and often asymptomatic until advanced stages of development and often leads to death. One of the factors that play a role in the occurrence of hypertension is a heavy metal, that is lead (Pb) which is used as an additional chemical mixture of gasoline. Gas station’s operator is one of the jobs are high-risk exposure to lead for a long time. This study aims to determine the association of blood lead levels with incidence of hypertension among the gas station’s operators in Kendari. This study used cross sectional design with observational analytic approach. The study was conducted at nine stations in Kendari and Forensic and Molecular Biology Laboratory, Faculty of Mathematics and Science, Haluoleo University, Kendari on 16 - 20 December 2016. Sample consisted of 30 operators of gas station, using proportional stratified sampling technique. The instrument used in this study were questionnaires and testing blood specimens in the laboratory by ashing method. Analysis of the data used in this study was Fisher Exact Test. The result showed respondents with normal blood lead levels are 6 respondents (20.0%) and abnormal blood lead levels are 24 respondents (80.0%). Respondents who have hypertension are 26 respondents (86.7%) and respondents who did not have hypertension are 4 respondents (13.3%). Respondents with normal lead levels who had hypertension totaled 2 respondents (6.7%) and who do not have hypertension totaled 4 respondents (13.3%). Respondents with abnormal lead levels who had hypertension totaled 24 respondents (100.0%) and who do not have hypertension numbered 0 respondents (0.0%). Based on the result of data analysis using the Fisher Exact statistical tests on the correlation of blood lead levels in the incidence of hypertension among the gas station’s operators in Kendari, p value = 0.001 which means that H0 is rejected. There is correlation between blood lead level with incidence of hypertension among the gas station’s operators in Kendari .Keywords: Lead in the blood, hypertension, gas station’s operator

Efek Larvasida Ekstrak Biji Buah Pepaya (Carica papaya L.) terhadap Larva Instar III Aedes aegypti L. Arimaswati Arimaswati; La Ode Muhammad Sawaluddin; Hittah Wahi Sudrajat
MEDULA JURNAL ILMIAH FAKULLTAS KEDOKTERAN UNIVERSITAS HALU OLEO Vol 4, No 2 (2017)
Publisher : Halu Oleo University

ABSTRACTThe larvacide Effects of Pawpaw’s Seed Extract (Carica papaya L) Againts Third Instar Larvae of Aedes aegypti L. (Biolarvacide Alternative Study). The aim of this research was to determine the Larvacide Effects of Pawpaw’s Seed Extract (C.papaya L) towards Third Instar Larvae of A. aegypti L. The research was conducted at the laboratory of Biology Education Department and laboratory of Chemistry Education Department, FKIP Halu Oleo University. Independent Variable (X) in the research is Pawpaw’s Seed Extract (C.papaya L) with concentration level are control or was not gived extract (X0), 0.125% (X1), 0.250% (X2), 0.375% (X3), 0.500% (X4), and 0.625% (X5) and Dependent variable (Y) is the mortality of Third Instar Larvae of Aedes aegypti L. The method in the research was used experimental method with Completely Randomized Design (CRD), 3 times repetitions, each group containing 20 larvae, so the total of sample were 360 larvae. The data analyze tecnic was used descriptive analyze to knowing the larvacide effect of Seed Extract (Carica papaya L) against the mortality of Third Instar Larvae of Aedes aegypti L., varians analyze and BJND test with a significant value 95% (α = 0.05) and probit analyze to calculate LC50value or lethal concentration 50%. The result of the descriptive analyzed shows in the control group there are not mortality of larvae. The highest concentration Pawpaw’s Seed Extract (Carica papaya L) was gived mortality of larvae is 0.625% (X5) or 100% (20 larvae) and low concentration is 0.125% (X1) or 45% (9 larvae). The result of sidik ragam analyze showing that the value of Fhitung> Ftabel, there was a significant influence of the Pawpaw’s Seed Extract (Carica papaya L) for the mortality of Third Instar Larvae of Aedes aegypti L.The result of probit analyzed is LC50 value was gived 50% mortality of larvae is 0.154%.Keywords :Pawpaw’s Seed Extract (Carica papaya L), Larvacide, Third Instar Larvae of Aedes aegypti L.

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Home Page

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Contact Name Sulastrianah

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Editorial Address Kampus Hijau Bumi Tridharma Anduonohu Kendari Universitas Halu Oleo Fakultas Kedokteran

Location Kota kendari, Sulawesi tenggara INDONESIA

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Contact Name
Sulastrianah

Contact Email
sulastrianahmuhtadi@gmail.com

Phone
+6285242541601

Journal Mail Official
sulastrianahmuhtadi@gmail.com

Editorial Address
Kampus Hijau Bumi Tridharma Anduonohu Kendari Universitas Halu Oleo Fakultas Kedokteran

Location
Kota kendari,

Sulawesi tenggara

INDONESIA