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Jurnal Ilmu Farmasi dan Farmasi Klinik (Journal of Pharmaceutical Science and Clinical Pharmacy)

Farmasi
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Published by Universitas Wahid Hasyim Semarang

ISSN : 16937899 EISSN : 27163814 DOI : 10.31942

Core Subject : Health,

Medicine & Pharmacology

Selamat datang di situs e-Publikasi Ilmiah Fakultas Farmasi Unwahas (Universitas Wahid Hasyim) Semarang. Situs ini berisi kumpulan publikasi ilmiah yang diterbitkan oleh Fakultas Farmasi Unwahas. Publikasi berasal dari jurnal-jurnal serta hasil prosiding seminar yang dilaksanakan oleh Fakultas Farmasi Unwahas.

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Search results for , issue "Prosiding Seminar Nasional "Peluang Herbal Sebagai Alternative Medicine"" : 24 Documents clear

Cover Dan Daftar Isi Prosiding Fakultas Farmasi
Jurnal Ilmu Farmasi dan Farmasi Klinik Prosiding Seminar Nasional "Peluang Herbal Sebagai Alternative Medicine"
Publisher : Universitas Wahid Hasyim Semarang

1PROSIDING SEMINAR NASIONAL PELUANG HERBAL SEBAGAI ALTERNATIF MEDICINE TAHUN 2015Penyunting: Yance Anas, M.Sc., Apt. FAKULTAS FARMASI UNIVERSITAS WAHID HASYIM SEMARANGSEPTEMBER 20152Penanggung jawab Dekan Fakultas Farmasi Universitas Wahid Hasyim Reviewer Dr. Rer. nat. Ronny Martien, M.Si. Prof. Dr. dr. Ignatius Riwanto Sp. B (D) Dr. Sumantri, M.Sc., Apt Dr. Mimiek Murukmihadi, SU., Apt Co reviewer Yance Anas, M.Sc., Apt Maulita Cut Nuria, M.Sc., Apt. Sri Susilowati, S.Si., M.Si., Apt. Yulias Ninik W., S.Si., M.Si., Apt. Prosiding Seminar Nasional Peluang Herbal Sebagai Alternatif Medicine Tahun 2015ISBN 978-602-19556-2-8 @ 2015, Fakultas Farmasi Universitas Wahid Hasyim Alamat : Fakultas Farmasi Universitas Wahid Hasyim Jl. Menoreh Tengah X/22 Sampangan Semarang Telp. 024-8505680, 8505681 Fax. 024-8505680E-mail : semnasherbaluwh@gmail.com Laman : www.farmasi.unwahas.ac.idwww.publikasiilmiah.unwahas.ac.idiKATA PENGANTARPuji syukur atas kehadirat Allah SWT sehingga Prosiding Seminar Nasional “Peluang Herbal Sebagai Alternative Medicine” telah berhasil diterbitkan. Prosiding ini berisikan 23 makalah hasil penelitian yang telah disampaikan oleh para peneliti pada acara Seminar Nasional “Peluang Herbal Sebagai Alternative Medicine”, baik yang disampaikan melalui presentasi oral ataupun poster. Makalah-makalah yang ada dalam prosiding ini juga dapat diunduh secara gratis oleh masyarakat melalui laman www.publikasiilmiah.unwahas.ac.id. Hasil penelitian yang disajikan dalam prosiding ini kami harapkan tidak hanya bermanfaat bagi peneliti saja, akan tetapi juga dapat dimanfaatkan oleh masyarakat luas. Ucapan terima kasih kami sampaikan kepada seluruh panitia seminar, peneliti, reviewer dan penyunting yang telah banyak membantu dalam penerbitan prosiding ini. Akhir kata, kami menghaturkan maaf yang sebesar-besarnya jika dalam penulisan prosiding ini terdapat suatu yang tidak berkenan di hati pembaca. Terima kasih atas perhatiannya dan selamat membaca. Semarang, 12 September 2015 Ketua Panitia Elya Zulfa, M.Sc., Apt.iiREVIEWER DAN PANITIA PENYELENGGARA REVIEWER Reviewer Dr. Rer. nat. Ronny Martien, M.Si. Prof. Dr. dr. Ignatius Riwanto Sp. B (D) Dr. Sumantri, M.Sc., Apt Dr. Mimiek Murukmihadi, SU., Apt Co reviewer Yance Anas, M.Sc., Apt Maulita Cut Nuria, M.Sc., Apt. Sri Susilowati, S.Si., M.Si., Apt. Yulias Ninik W., S.Si., M.Si., Apt. SUSUNAN PANITIA PENYELENGGARAPelindung:Rektor Universitas Wahid Hasyim SemarangPenanggung jawab:Dekan Fakultas Farmasi Universitas Wahid Hasyim SemarangPenasehat:1. Prof. Dr. H. Mahmutarom, SH, M. Hum2. Dr. Sumantri, M. Sc., Apt3. Drs. Jamaluddin Al J Effendi., AptKetua:Elya Zulfa M. Sc., AptSekretaris:Yuni Warniyati, A.MdBendahara:Khotimatul Khusna, SESeksi – seksiSeksi publikasi, dekorasi, dan DokumentasiKoordinator:Sugiyono, M. Sc., AptAnggota:Rachmad WahyudiSeksi dana dan usahaKoordinator:Risha Fillah F, M.Sc., AptAnggota:Dwi Meilani, A. MdSeksi kesekretariatanKoordinator:Sugito Chandra S. FarmAnggota:Imam Asrofi S. FarmiiiSeksi perlengkapan danTransportasiKoordinator:Ari Supriyono, A. MdAnggota:M. Shalahuddin al ayubiSeksi acaraKoordinator:Ibrahim Arifin M. Sc., AptAnggota:Aqnes Budiarti M. Sc., AptKiki Damayanti S. FarmRirin Lispita W, S. Farm., AptDevi Nisa H, M. ScDewi Andini K.M S. FarmSeksi KonsumsiKoordinator:Hanik Atiqoh , S.KMAnggota:Azi Zaujan, S. IPSeksi IlmiahKoordinator:Yance Anas M.Sc., AptAnggota:Dr. Sumantri, M.Sc., AptSri Susilowati, M.Sc., AptYulias Ninik W, M.Si., AptMaulita Cut Nuria, M.Sc., AptivDAFTAR ISIKATA PENGANTAR …………………………………………………………………iREVIEWER DAN PANITIA PENYELENGGARA ………………………………….iiDAFTAR ISI …………………………………………………………………………..ivA. FARMAKOLOGI DAN FARMASI KLINIKA1.Perbedaan Efektivitas Antibiotik Terapi Demam Tifoid Di Puskesmas Bancak Kabupaten Semarang Tahun 2014 Risha Fillah Fithria, Kiki Damayanti dan Risma Putri Fauzia …………..1-6A2.Potensi Fraksi N-Heksan Ekstrak Etanol Rimpang Lengkuas [Alpinia galanga (L.) Swartz.] Dalam Meningkatkan Kualitas Sperma Dan Spermatogenesis Yance Anas, Imam Faozi dan Suharjono …..………………………………7-19A3.Isoproterenol Sebagai Model Infark Miokard Akut pada Hewan Uji Tikus Wistar Wahyu Widyaningsih, Sugiyanto, Sitarina Widyarini dan Suwidjiyo Pramono …………………………………………………………..20-27A4.Pengukuran Kualitas Hidup Pasien Tuberkulosis dengan Menggunakan Instrumen Saint George Respiratory Questionnaire (SGRQ) di Yogyakarta Hendrik, Dyah Aryani Perwitasari, Ully Adhie Mulyani dan Jarir At Thobari ……………………………………………………………………….28-34A5.Studi Klinis Formula Jamu Antihiperglikemia terhadap Fungsi Hati Fajar Novianto dan Agus Triyono ………………………………………….35-41A6.Uji Toksisitas Akut dan Subkronik Ramuan Jamu untuk Fam (Fibroadenoma Mammae)Saryanto dan Danang Ardiyanto ……………………………………………42-50A7.Kolaborasi Ekstrak Metanol Daun Kenikir (Cosmos caudatus, Kunth) dan Doksorubisin terhadap Sel Kanker Payudara T47D Fera Elia Fita, Dewi Listianingsih, Yunita Ayu Hapsari, Raka Galih Pradana, Erika Indah Safitri dan Ibrahim Arifin …………………………51-56A8.Uji Klinik Multisenter Pengaruh Formula Jamu Osteoarthritis terhadap Rasa Nyeri Dibanding Piroxicam Danang Ardiyanto dan Peristiwan R Widhi Astana ………………………57-61A9Studi Klinik Efek Seduhan Formula Jamu Hipertensi terhadap Fungsi Ginjal Agus Triyono dan Fajar Novianto .................................................................62-65A10Analisis Kinerja Instalasi Farmasi Rumah Sakit Umum Daerah X dengan Pendekatan Balanced Scorecard pada Perspektif Proses Bisnis Internal Indriyati Hadi Sulistyaningrum …………………………………………….66-70A.11Uji Efek Analgetik Antipiretik Ekstrak Etanol Alfafa (Medicago sativa) pada Tikus Putih Jantan Galur Wistar AA. Hesti Wulan S., Uning Rininingsih EM. dan Ika Puspitaningrum ….71-77A.12Pengaruh Kombinasi Ekstrak Etanol Daun Sirsak (Annona muricata L.) dan Gemfibrozil Terhadap Kadar Trigliserida Dan Hdl Tikus Yang Diinduksi Pakan Tinggi Lemak Ririn Lispita Wulandari, Sri Susilowati dan Sucyati Amelia ……………..78-84vA.13Evaluasi Peresepan Antibiotik Pasien Infeksi Saluran Kemih di Instalasi Rawat Inap Rumah Sakit Roemani Semarang Hening Pratiwi dan Septimawanto Dwi P…………………………………..85-91B. FARMASETIKA DAN TEKNOLOGI FARMASIB1.Ekstrak Biji Alpukat sebagai Pembusa Deterjen: “Pemanfaatan Potensi Bahan Alam untuk Bahan Tambahan Deterjen untuk Menggantikan Bahan Tambahan Impor dan Menekan Biaya Produksi” Hazena Misgi Damayanti, Nabila Annisa Praditia, Reni Widaya Murti, Midar Ahmad dan Naniek Widyaningrum ………………………………..92-98B2.Uji Kelarutan Untuk Seleksi Fase Minyak, Surfaktan dan Kosurfaktan dalam Preparasi Self-Nano Emulsifying Drug Delivery System (SNEDDS) Furosemid Iis Wahyuningsih, Sugiyanto, Yuswanto dan Ronny Martein ……………99-104C. KIMIA FARMASIC.1Uji Aktivitas Antioksidan Ekstrak Etanol Daun Karika (Carica pubescens) dengan Metode DPPH (1,1-difenil-2-pikrilhidrazil) beserta Identifikasi Senyawa Alkaloid, Fenolik dan Flavonoid Indranila dan Maria Ulfah …………………………………………………..105-111C.2Uji Aktivitas Antioksidan Ekstrak Etil Asetat Kulit Akar Senggugu (Clerodendrum serratum) Asal Imogiri, Yogyakarta Nasrudin, Wahyono, Mustofa dan Ratna Asmah112-117C.3Uji Aktivitas Antioksidan Fraksi n-Heksan Ekstrak Etanol Daun Karika (Carica pubescens) dengan Metode DPPH(1,1-difenil-2-pikrilhidrazil) beserta Identifikasi Senyawa Alkaloid dan Flavonoid Annis Mu’awwanah dan Maria Ulfah ……………………………………...118-124C.4Potensi Rimpang Kencur (Kaempferia galanga L.) sebagai Pencegah Osteoporosis dan Penurun Kolesterol Pada Wanita Menopause melalui Studi In Vivo dan In Silico Sri Handayani, Fera Elia, Siti Istatoah, Erika Indah dan.Ibrahim Arifin..125-133C.5Pengaruh Suhu dan Lama Penyimpanan terhadap Kandungan Vitamin C dalam Cabai Merah (Capsicum annuum. L) dan Aktivitas Antioksidannya Menggunakan Metode DPPH Aqnes Budiarti dan Dyah Ayu Elisa Kurnianingrum ..................................134-140D. BIOLOGI FARMASID.1Aktivitas Antibakteri Formula Optimum Krim Fraksi Etil Asetat Ekstrak Daun Teh Hijau (Camelia sinensis L) sebagai Sediaan Topikal Antijerawat Naniek Widyaningrum, Achmad Fudholi, Sudarsono dan Erna P. Setyowati ……………………………………………………………. 141-146D.2Standarisasi Spesifik dan Non Spesifik Ekstraksi Hidrotropi Andrographolid dari Sambiloto (Andrographis paniculata) Rita Dwi Ratnani, Indah Hartati, Yance Anas, Devi Endah P. dan Dita Desti D. Khilyati …………………………………………………... 147-155D.3Optimasi CMC-Na dan Karbomer sebagai Pengikat pada Formula Pasta Gigi Triklosan secara SLD Elya Zulfa, Fajar Indah dan Mimiek Murukmihadi………………………………. 156-162

PERBEDAAN EFEKTIVITAS ANTIBIOTIK PADA TERAPI DEMAM TIFOID DI PUSKESMAS BANCAK KABUPATEN SEMARANG TAHUN 2014 Risha Fillah Fithria; Kiki Damayanti; Risma Putri Fauziah
Jurnal Ilmu Farmasi dan Farmasi Klinik Prosiding Seminar Nasional "Peluang Herbal Sebagai Alternative Medicine"
Publisher : Universitas Wahid Hasyim Semarang

ABSTRACTThere are differences on the use of antibiotics on typhoid fever’s treatment. However, there was a research concluded that there were no differences between the efficacy of antibiotics on typhoid fever's therapy that shown as fever-free time and treatment duration. The purposes of this study are to determine the various antibiotics that used on typhoid fever’s treatment and to compare the efficacy of that antibiotic at Bancak Public Health Center Semarang regency. This study was an analytically survey research, with retrospective data collection from medical records, used purposive sampling method. The research sample was all adult patients’ typhoid fever hospitalization at Bancak Public Health Center Semarang regency. Data of antibiotic’s efficacy in fever-free time and treatment duration were analyzed with Kruskal-Wallis test. The result showed that the antibiotics used on typhoid fever’s treatment at Bancak Public Health Center Semarang regency were chloramphenicol, amoxicillin, cefotaxime, ceftriaxone, and ampicillin. Ceftriaxone was an antibiotic that provided the shortest fever's free-time and duration of treatment. However, there was no statistically significant difference between efficacy of that antibiotics at Bancak Public Health Center Semarang regency (p>0.05). Key words : Antibiotics efficacy, typhoid fever’s treatment, fever’s free-time, duration of treatment, Bancak Public Health Center.

POTENSI FRAKSI n-HEKSAN EKSTRAK ETANOL RIMPANG LENGKUAS [Alpinia galanga (L.) Swartz.] DALAM MENINGKATKAN KUALITAS SPERMA DAN SPERMATOGENESIS Yance Anas; Imam Faozi; Suharjono Suharjono
Jurnal Ilmu Farmasi dan Farmasi Klinik Prosiding Seminar Nasional "Peluang Herbal Sebagai Alternative Medicine"
Publisher : Universitas Wahid Hasyim Semarang

ABSTRACT Flavonoids and steroid's compounds have been identifying in the galangal rhizome [Alpinia galanga (L.) Swartz.]. This compound has hormonal and antioxidant effects and can improve the spermatogenesis and quality of spermatozoa. The purpose of this study is to find out the effects of the n-hexane fractions from galangal rhizome ethanol extract (HFGREE) on male Swiss mice spermatogenesis and quality of spermatozoa. This research is a laboratory experimental with randomized matched post test only controls group design. Twenty-four male Swiss mice (8-weeks old) divided among four groups: control groups (mice treated with CMC 1.0% 10 mL.kg-1.day-1), and three groups of mice treated with HFGREE (1.29; 2.58 and 5.16) mg.kg-1.day-1 for 30 days. All mice sacrificed at day 31. Furthermore, testicular tissue sections are used to calculate the score of spermatogenesis. Spermatozoa in the epididymis were used to assess the quality of spermatozoa. The results showed the HFRGEE (2.58 and 5.16) mg.kg-1.day-1 for 30 days, significantly elevate spermatogenesis score, and improve the spermatozoa count, spermatozoa motility, healthy and normal spermatozoa of male Swiss mice (p<0.05). Further studies can focus on the identification of active compounds in HFGREE that play a role in improving spermatogenesis and quality of spermatozoa. Key words: n-hexane fraction, galangal rhizome ethanol extract, spermatogenesis, quality of spermatozoa

ISOPROTERENOL SEBAGAI MODEL INFARK MIOKARDIAL AKUT PADA TIKUS WISTAR Wahyu Widiyaningsih; Sugiyanto Sugiyanto; Sitarina Widyarini; Suwidjiyo Pramono
Jurnal Ilmu Farmasi dan Farmasi Klinik Prosiding Seminar Nasional "Peluang Herbal Sebagai Alternative Medicine"
Publisher : Universitas Wahid Hasyim Semarang

ABSTRACT Decreased oxygen supply and necrosis in the heart muscle cells can lead to acute myocardial infarction. Free radical compounds can lead to oxidative stress in the heart muscle and lead to myocardial infarction. Isoproterenol is a non-selective β-adrenergic agonist can lead to acute myocardial infarction in large doses. The purpose of this study was to validate the model of acute myocardial infarction. This study using male Wistar rats aged two months as the test animal. Male Wistar rats divided into two groups: control group and treatment group. The control group treated with physiological saline and the treatment group treated with isoproterenol 85 mg/kg BW. Isoproterenol administered subcutaneously for two doses with an interval of 24 hours. After 48 hours of the isoproterenol first administration, rat heart rhythm's records with an electrocardiogram (ECG). Furthermore, the rats sacrificed and performed a necropsy. The left ventricle part in the cross section for the macroscopic observation (extensive infarction) with triphenyl tetrazolium chloride (TTC) staining, microscopic observation of infarction with hematoxylin-eosin staining (HE) and immunohistochemical (IHC) to observe the expression of caspase-3. The ECG of isoproterenol group showed elevation in the ST segment. TTC staining shows the expansion of the infarct area. The HE staining showed the typical image of myocardial infarction and the IHC staining results showed an increase in the expression of caspase-3. The results showed that isoproterenol can be use as a model myocardial infarction with parameters of infarction are ECG changes, TTC staining of infarct broad macroscopic image, a histopathological image of heart and apoptosis with the expression of caspase-3. Key words: Isoproterenol, acute myocardial infarction, cardiac histopathology

PENGUKURAN KUALITAS HIDUP PASIEN TUBERKULOSIS MENGGUNAKAN INSTRUMEN ST GEORGE RESPIRATORY QUESTIONNAIRE (SGRQ) DI YOGYAKARTA Hendrik Hendrik; Dyah Aryani Perwitasari; Ully Adhie Mulyani; Jarir At Thobari
Jurnal Ilmu Farmasi dan Farmasi Klinik Prosiding Seminar Nasional "Peluang Herbal Sebagai Alternative Medicine"
Publisher : Universitas Wahid Hasyim Semarang

ABSTRACT Tuberculosis (TB) is an infectious disease caused by the bacillus Mycobacterium tuberculosis. It typically affects the lungs but can affect other sites as well. TB disease could influence the TB patients’ quality of life such as psychology of health, physical function and the leading role in society. The purpose of this research is to measure the differed TB patients’ quality of life before and during the treatment using Indonesian version of St George Respiratory Questionnaire (SGRQ) instruments that have been validated. The research used a cross-sectional design conducted prospectively in 91 new patients diagnosed as lung TB in BP4 province of Yogyakarta in November 2013 until April 2015. Patients filled out the questionnaires, and its obtained Total Score values were analyzed with Friedman's test to understand the quality of life. The results from this research showed that the quality of life of TB patient before, and during the treatment differed significantly. The Total score on the first month treatment was 43.57% and the second until the sixth months treatment was 30.40%; 25.22%; 20.50%; 18.45% and 16.51% respectively (p<0.05). The worst of quality of life was occurred in the first month treatment as the initial period before the treatment and continues to improve until the sixth-month treatment. In conclusion, the quality of life TB patients’ before and during the treatment is more increasing. Key words: Tuberculosis, SGRQ, Quality of life.

UJI TOKSISITAS AKUT DAN SUB KRONIS RAMUAN JAMU UNTUK FIBRO ADENOMA MAMMAE (FAM) Saryanto Saryanto; Danang Ardiyanto
Jurnal Ilmu Farmasi dan Farmasi Klinik Prosiding Seminar Nasional "Peluang Herbal Sebagai Alternative Medicine"
Publisher : Universitas Wahid Hasyim Semarang

ABSTRACT Mammary fibroadenomas (FAM) is the mammary gland benign tumor and has a high incidence rate in women aged 20-30 years. The purposes of this study are to assess the acute and subchronic toxicity of the herbs for FAM. The herb for FAM is a mixture of several simplisia (Curcuma zedoaria Rosch. rhizome; Loranthus parasiticus; Curcuma mangga Val. rhizome and Mammeria mimosa tuber) with a (10 g: 10 g: 5 g: 8 g: 7 g) ratio. Acute toxicity assay performed on the male and female Spraque-Dawley (SD) rats (aged 2-3 months with 200-250 g body weight). Forty-eight rats divided into four treatment groups (control group and three treatment groups of herbs for FAM). A decoction of herbs for FAM treated once a day orally. Toxicity clinical symptoms and lethal doses (LD50) observed for 7-14 days. Subchronic toxicity assay was also conducted in the male and female SD rats (aged 1.5-2 months with 150-200 g body weight). The three-dose series of herbs for FAM treated to the rats orally once daily for 90 days. The results of acute and subchronic toxicity assays found the quasi LD50 value of herbs for FAM is 5.000 mg/kg BW. This herb is safe for use in the medium term as an herbal medicine for FAM. Key words: FAM, acute, subchronic, toxicity assay

EFEK SITOTOKSIK KOMBINASI EKSTRAK METANOL DAUN KENIKIR (Cosmos caudatus, Kunth) DAN DOKSORUBISIN TERHADAP SEL KANKER PAYUDARA T47D SECARA IN-VITRO DAN IN-SILICO Fera Elia Fita; Dewi Listianingsih; Yunita Ayu Hapsari; Raka Galih Pradana; Erika Indah Safitri; Ibrahim Arifin
Jurnal Ilmu Farmasi dan Farmasi Klinik Prosiding Seminar Nasional "Peluang Herbal Sebagai Alternative Medicine"
Publisher : Universitas Wahid Hasyim Semarang

ABSTRACTDoxorubicin is chemotherapeutic agents used widely for breast cancer therapy. The use of doxorubicin may cause cardio toxicity and multi-drug resistance. In order to overcome this side effect, a combined therapy using the methanol extracts of kenikir leaves is developed. The purposes of this study are to measure the cytotoxic effect of methanol extracts of kenikir leaves and doxorubicin combination treatment against T47D breast cancer cell growth in-vitro and in-silico, as well as determining the optimal dose combination that produces the most potent cytotoxic effects. The extraction of kenikir leaves is performed with soxhletation method. The cytotoxicity assay on the T47D breast cancer cells is carried out using MTT assay. The result of this research shows that the value of IC50 methanol extracts of kenikir leaves is 778.05μg/mL. The treatment of the methanol extracts of kenikir leaves and doxorubicin combination treatment results in a strong synergy at the concentration 130 μg/mL (-41 nM); 195 μg/mL (-41 nM) and 130 μg/mL (-27.33 nM) with the value of Combination Index 0.2; 0.3 and 0.3 respectively. The result of in-silico test shows that the bond energies of aglycone flavonoid and quercetin glycoside on Bcl-2 are -63.3359 and -67.0414. Key words: Kenikir leaves extract, doxorubicin, T47D cells, molecular docking

UJI KLINIK MULTISENTER PENGARUH FORMULA JAMU OSTEOARTHRITIS TERHADAP RASA NYERI DIBANDING PIROXICAM Danang Ardiyanto; Peristiwan R Widhi Astana
Jurnal Ilmu Farmasi dan Farmasi Klinik Prosiding Seminar Nasional "Peluang Herbal Sebagai Alternative Medicine"
Publisher : Universitas Wahid Hasyim Semarang

ABSTRACT Herb scientification program is expected to obtain scientific evidence of the use of herb through research-based services. The purpose of this study is to reveal the efficacy of pain relief herb for osteoarthritis (OA) compared to the standard drug piroxicam. This clinical study performed through multi-center clinical trial approach involving 30 physicians who have been trained in herbs scientification trainee in February to December 2014. The study design was an open clinical trial without blinding. 123 patients with OA who met the inclusion criteria included in this study and they divided into two groups (63 subjects treat with OA herb and 60 subjects treated with piroxicam (as a control group). The OA herb consists (Curcuma xanthorrhiza roxb rhizome (15 g), Phyllanthus urinaria herbs (7 g), Curcuma domesticae rhizoma (15 g), Foeniculum vulgare Mill seeds (3 g), Orthosiphon aristatus leaves (5 g), and Acalyptha india herb (5 g)). Data collected for four weeks in both groups of patients. This clinical study concludes that the treatment of OA herb for 28 days significantly decrease the pain in patients with osteoarthritis. OA herbs can reduce the patient's VAS scores were comparable to piroxicam (p> 0.05). Key words: Osteoarthritis, pain relief herb, VAS, piroxicam

STUDI KLINIK EFEK SEDUHAN FORMULA JAMU HIPERTENSI TERHADAP FUNGSI GINJAL Agus Triyono; Fajar Novianto
Jurnal Ilmu Farmasi dan Farmasi Klinik Prosiding Seminar Nasional "Peluang Herbal Sebagai Alternative Medicine"
Publisher : Universitas Wahid Hasyim Semarang

ABSTRACT Clinical study on the effect of hypertension herbs steeping formula on the renal functions has been done. Hypertension herb formula consists of Apium graveolens L.; Orthosiphon spicatus (Thunb.); Centella asiatica (L.); Curcuma xantoriza; Phyllantus niruri, and Curcuma domestica. Clinical trials were conducted by open-label clinical trial and pre-post test design. Thirty human subjects who have met the inclusion and exclusion criteria were involved in this study. The study protocol was approved by the research ethics of Ethics Committee for Health Research, National Institute of Health Research and Development, Ministry of Health. Before the treatment, the subjects who had signed informed consent performed anamnesis, medical history, clinical symptoms, physical examination and laboratory tests of renal function (BUN and creatinine levels). The subjects treat with the hypertension herbs steeping formula three times a day for eight weeks, then controlled it once a week. Anamnesis on the clinical symptoms, the possibility of side effects and physical examination diagnostic on the subject performed every week. Measurement on the renal function performed every four week. Base on the anamnesis and physical examination, the clinical study concluded that there were no significant adverse effects on the subject. Paired t-test results showed that there was no significant difference on subject’s BUN and creatinine levels before and after the treatment hypertension herbs steeping formula on the 28th and 56th day (p <0.05). Clinically, the treatment of hypertension herb steeping formula for 56 days did not affect the subject’s renal function. Key words: Hypertension herbs steeping formula, renal function

ANALISIS KINERJA INSTALASI FARMASI RSU DAERAH X DENGAN PENDEKATAN BALANCED SCORECARD PADA PERSPEKTIF PROSES BISNIS INTERNAL Indriyati Hadi Sulistyaningrum
Jurnal Ilmu Farmasi dan Farmasi Klinik Prosiding Seminar Nasional "Peluang Herbal Sebagai Alternative Medicine"
Publisher : Universitas Wahid Hasyim Semarang

ABSTRACT Balanced Scorecard offers the solution for comprehensive performance measurement in a public organization such as a hospital. The purpose of this study is to evaluate the department of pharmacy of RSUD X performance using a balanced scorecard approach refers to internal business perspective. The object of this study is pharmacy department of RSUD X as government district hospitals. This study is a descriptive non-experimental. Data were collected prospectively. The qualitative data obtained through questionnaires and in-depth interviews with the Chief of Pharmacy Department of RSUD X. The quantitative data are dispensing time, drug availability level and interconnection out-patient, obtained through direct observation and surveys on drugs in outpatient prescription. The result showed that the average dispensing times for compounded and non-compounded prescriptions are 21 and 15 minutes respectively. The average of drug availability level in 2012 was 98%. The general interconnection out-patients were at 99%. Therefore, it can be concluded that pharmacy department performance level of RSUD X was categorized in “sufficient criteria”, with some suggestions for improvement. Key words: Performance analysis, balanced scorecard, pharmacy department, RSUD X.

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All Issue Vol 20, No 1 (2023): Jurnal Ilmu Farmasi & Farmasi Klinik 2023: [Special Edition] Jurnal Ilmu Farmasi & Farmasi Klinik Vol 19, No 2 (2022): Jurnal Ilmu Farmasi & Farmasi Klinik Vol 19, No 1 (2022): Jurnal Ilmu Farmasi & Farmasi Klinik Vol 18, No 01 (2021): Jurnal Ilmu Farmasi & Farmasi Klinik Vol 18, No 2 (2021): Jurnal Ilmu Farmasi & Farmasi Klinik Vol 17, No 2 (2020): Jurnal Ilmu Farmasi & Farmasi Klinik Vol. 17 N0. 02 Desember 2020 Vol 17, No 01 (2020): Jurnal Ilmu Farmasi & farmasi Klinik Vol 17 No. 01, Juni 2020 Vol 16, No 02 (2019): Jurnal Ilmu Farmasi & farmasi Klinik Vol 16 No 02 Desember 2019 Jurnal Ilmu Farmasi & farmasi Klinik Vol 16 No 1 Juni 2019 Jurnal Ilmu Farmasi & Farmasi Klinik Vol 15 No 2 Desember 2018 Jurnal Ilmu Farmasi & Farmasi Klinik Vol 15 No 1 Juni 2018 Jurnal Ilmu Farmasi & Farmasi Klinik Vol 14 No 2 Desember 2017 Jurnal Ilmu Farmasi & Farmasi Klinik Vol 14 No 1 juni 2017 Prosiding Seminar Nasional "Peluang Herbal Sebagai Alternative Medicine" Jurnal Ilmu Farmasi & Farmasi Klinik Vol 13 No 2 Desember 2016 JURNAL ILMU FARMASI & FARMASI KLINIK VOL. 13 NO. 1 JUNI 2016 Jurnal Ilmu Farmasi & Farmasi Klinik Volume 12 No.2 Desember 2015 Jurnal Ilmu Farmasi & Farmasi Klinik Volume 12 No. 1 Juni 2015 JURNAL ILMU FARMASI DAN FARMASI KLINIK VOL.11 NO.2 DESEMBER 2014 JURNAL ILMU FARMASI DAN FARMASI KLINIK VOL.11 NO.1 JUNI 2014 Prosiding Seminar Nasional "Perkembangan Terbaru Pemanfaatan Herbal Sebagai Agen Preventif Pada Tera Jurnal Ilmu Farmasi & Farmasi Klinik Vol.10 No.1 Juni 2013 Jurnal Ilmu Farmasi & Farmasi Klinik Vol.10 No.1 Juni 2013 Jurnal Ilmu Farmasi & Farmasi Klinik Vol.9 No.2 Desember 2012 Prosiding Seminar Nasional "Peranan dan Kontribusi Herbal dalam Terapi Penyakit Degeneratif" JURNAL ILMU FARMASI DAN FARMASI KLINIK VOL. 7 NO. 2 DESEMBER 2010 JURNAL ILMU FARMASI DAN FARMASI KLINIK VOL. 6 NO. 1 JUNI 2009 JURNAL ILMU FARMASI DAN FARMASI KLINIK VOL. 5 NO. 2 DESEMBER 2008 JURNAL ILMU FARMASI DAN FARMASI KLINIK VOL. 5 NO. 1 JUNI 2008 JURNAL ILMU FARMASI DAN FARMASI KLINIK VOL. 4 NO. 1 JUNI 2007 More Issue

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Contact Name
-

Contact Email
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Journal Mail Official
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Editorial Address
-

Location
Kota semarang,

Jawa tengah

INDONESIA