Jambi Medical Journal "Jurnal Kedokteran dan Kesehatan"
Jambi Medical Journal is a Journal for Medical And Health Issues, in Scope: Medical Education, Farmakology, Mikrobiology, PUblic Health, Clinical Patology, Medical Nutrition, Clinical Medicine, Pediatric, Immunology, Patology Anatomi, Orthopedy, Obstetri and Gynekology, Internal Medicine, Endocrine and Metabolic, Genetics & Molecular Biology.
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"Vol. 11 No. 1 (2023): Jambi Medical Journal: Jurnal Kedokteran dan Kesehatan"
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<![CDATA[FAKTOR-FAKTOR YANG BERHUBUNGAN DENGAN KEJADIAN KUSTA DI WILAYAH KERJA PUSKESMAS MUARA SABAK TIMUR KABUPATEN TANJUNG JABUNG TIMUR ]]>
<![CDATA[Willia Novita]]>;
<![CDATA[Oka Lesmana]]>;
<![CDATA[Pitoyo]]>
<![CDATA[ Jambi Medical Journal : Jurnal Kedokteran dan Kesehatan Vol. 11 No. 1 (2023): Jambi Medical Journal: Jurnal Kedokteran dan Kesehatan ]]>
Publisher : <![CDATA[FAKULTAS KEDOKTERAN DAN ILMU KESEHATAN UNIVERSITAS JAMBI ]]>
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DOI: 10.22437/jmj.v11i1.16939
<![CDATA[Background: Tanjung Jabung Timur Regency is ranked first in leprosy cases in 2019 with a total of 36 cases. In 2020 East Tanjung Jabung Regency recorded 14 new cases of leprosy. The Muara Sabak Timur Health Center is one of the health centers with the highest leprosy with a total of 25 cases until 2020. Objective: The purpose of this study was to determine the factors associated with the incidence of leprosy in the working area of the Muara Sabak Timur Health Center. Method: The design of this study uses a case control approach. The sample in the study used a 21 case group samples and 21 control group samples. Results: From the statistical test results contact history variable p-value 0.147 (OR 1.105), humidity variable p-value 0.334 (OR 1.875), ventilation area variable p-value 0.001 (OR 10.625), occupancy density variable p-value 0.000 (OR 15.438), clean water availability variable p-value 0.204 (OR 2.273), toilet ownership variable p-value 0.040 (OR 4.500), house floor variable p-value 0.707 (OR 1.328), and personal hygiene variable p-value 0.013 (OR 5,200). Conclusion: leprosy is highly contagious, especially in conditions of poor personal hygiene, crowded housing, and latrines and ventilation that do not meet health requirements. Keywords: Leprosy, personal hygiene, ventilation, humidity, residential density]]>
<![CDATA[RESECTION AND RECONSTRUCTION OF GIANT TOPHUS OF THE FOOT : A CASE REPORT ]]>
<![CDATA[Rhyan Darma Saputra]]>;
<![CDATA[Bintang Soetjahjo]]>;
<![CDATA[Bagus Jati Nugroho]]>;
<![CDATA[Jiva Yori Anugrah]]>
<![CDATA[ Jambi Medical Journal : Jurnal Kedokteran dan Kesehatan Vol. 11 No. 1 (2023): Jambi Medical Journal: Jurnal Kedokteran dan Kesehatan ]]>
Publisher : <![CDATA[FAKULTAS KEDOKTERAN DAN ILMU KESEHATAN UNIVERSITAS JAMBI ]]>
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DOI: 10.22437/jmj.v11i1.17375
<![CDATA[Background: The first metatarsophalangeal joint is the most frequent site of gouty tophi (MTP1). With the incidence of MTP1 joint was 73 %. Treatment aims at control of serum uric acid levels which can cause regression of tophi and surgical excision of very large tophi. A case of a massive tophus at the first metatarsophalangeal joint was documented. Case presentation: A 58-year-old man was diagnosed with and a huge tophus at MTP1,after a five-year history of the gout disease. The patient was referred to our hospital because of a developing mass. On examination of the left foot, there was a solid mass on the dorsal and plantar forefoot that was fixed and had an unclear margin. There was no discomfort on the lump. The 1st metatarsal and proximal phalanges bones were both destroyed on a plain radiograph of the left foot. A laboratory examination shown increased at uric acid level (11.3 mg/dl), increased at sedimentation rate (46 mm/h at first hour), and also increased lactate dehydrogenase (LDH). We performed Excision of tophi and continued with reconstruction and arthrodesis MTP1 & MTP2 using iliac auto bone graft then internally stabilized with Mini T-Plate and K-Wire Conclusion: Patient with giant tophus at first metatarsophalangeal joint can be treated with excision and performed arthrodesis. Keywords: First metatarsophalangeal, giant tophus, arthrodesis]]>
<![CDATA[HUBUNGAN MIOPIA DENGAN AMPLITUDO AKOMODASI PADA SISWA SMP NEGERI DI KOTA PADANG ]]>
<![CDATA[Rozy Oneta]]>;
<![CDATA[Kemala Sayuti]]>;
<![CDATA[Rinda Wati]]>
<![CDATA[ Jambi Medical Journal : Jurnal Kedokteran dan Kesehatan Vol. 11 No. 1 (2023): Jambi Medical Journal: Jurnal Kedokteran dan Kesehatan ]]>
Publisher : <![CDATA[FAKULTAS KEDOKTERAN DAN ILMU KESEHATAN UNIVERSITAS JAMBI ]]>
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DOI: 10.22437/jmj.v11i1.20455
<![CDATA[Background: Decrease in eye accommodation response is a result of eye growth in children with myopia. Less than normal accommodation response to near focus increased lag of accommodation which decreased image quality of the retina due to hyperopic defocus. If it left uncorrected over a prolonged period of time, it will activate feedback mechanism which ultimately increases progression of myopia. Objective: This study aims to determine the relationship between myopia and accommodation amplitude in junior high school students in Padang city. Methods: This was a cross-sectional study involved 384 students with myopia from four state junior high schools in Padang. Visual acuity was determined using Snellen Chart, and refractive error was diagnosed by autorefractometer. The amplitude of accommodation was measured by RAF rule (Zabby). Results: Based on the degree of myopia, we found 64.58% low myopia, 27.87% moderate myopia, and 7.55% high myopia. The mean amplitude of accommodation in low myopia was 13.73 ± 1.30 Diopters, moderate myopia 10.52 ± 1.26 Diopters, and high myopia 8.41 ± 0.60 Diopters. Significant decreased in amplitude of accommodation were found between low versus moderate myopia, low versus high myopia, also moderate versus high myopia. Conclusion: there is significant correlation between myopia and amplitude of accommodation (p <0,05), higher grades of myopia show decreasing amplitude of accommodation. Keywords:myopia, amplitude of accommodation, RAF rule.]]>
<![CDATA[A CASE REPORT: THE STRATEGY OF CORNEAL ULCERS ]]>
<![CDATA[Kuswaya Waslan]]>;
<![CDATA[Rahayu Oktaliani]]>
<![CDATA[ Jambi Medical Journal : Jurnal Kedokteran dan Kesehatan Vol. 11 No. 1 (2023): Jambi Medical Journal: Jurnal Kedokteran dan Kesehatan ]]>
Publisher : <![CDATA[FAKULTAS KEDOKTERAN DAN ILMU KESEHATAN UNIVERSITAS JAMBI ]]>
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DOI: 10.22437/jmj.v11i1.20483
<![CDATA[Introduction: Corneal ulcers are considered an ophthalmologic emergency because of their potential to permanently impair vision or perforate the eye. Accurate and quick diagnosis and prompt treatment is a key to improve clinical and visual outcomes in cases of corneal ulceration. In case of medical treatment failure, resulting in ulcer perforation, surgical care is required. Here we make an attempt to provide an overview on diagnostic approach and management protocol of corneal ulcer. Case Presentation: In this paper, we present the case of male 40-year-old presented with complaints of pain and defective vision in the right eye. Visual examination of the right eye is 1/~. It was found, palpebral edema, hyperemic tarsal conjunctiva. The bulbar conjunctiva showed conjunctival injection, ciliary injection. The cornea looks completely cloudy, the surface is not slippery, infiltrates and edema. The patient was treated with medical and surgical therapy, and then the patient’s have a good clinical response and was able to return to work. Conclusion: Indonesian farmers have highrisk of fungal corneal ulcers. Fungal corneal ulcers is important cause of corneal blindness all over the world especially in develoving countries. Fungal corneal ulcers can diagnosis by slitlamp biomicroscopic examination and culture are essential for early specific diagnosis and must be taken consideratiaon to establish the most effective treatment and avoid severe complications. Keywords: Fungal Corneal Ulcers, Blindness, Optimal Treatment of Corneal Ulcers, Tissue Discontinuity]]>
<![CDATA[ADVANTAGES OF MINIMALLY INVASIVE SPINE SURGERY FOR THE TREATMENT OF THORACOLUMBAR FRACTURES: A SYSTEMATIC REVIEW ]]>
<![CDATA[Arfan Surya Adhitama]]>;
<![CDATA[Rieva Ermawan]]>
<![CDATA[ Jambi Medical Journal : Jurnal Kedokteran dan Kesehatan Vol. 11 No. 1 (2023): Jambi Medical Journal: Jurnal Kedokteran dan Kesehatan ]]>
Publisher : <![CDATA[FAKULTAS KEDOKTERAN DAN ILMU KESEHATAN UNIVERSITAS JAMBI ]]>
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DOI: 10.22437/jmj.v11i1.20892
<![CDATA[Background: Thoracolumbar spine fractures are the most common vertebral fractures. Trauma to the thoracolumbar spine can cause disability, spinal deformity, neurological deficits, psychological, economic and social problems. Safe and effective treatment is very important. Currently, the miss approach is only used for the management of type A (AO classification) and stable thoracolumbar fractures. Objective: this systematic review aims to determine the advantages of using the miss approach compared to the open approach in the treatment of thoracolumbar fractures. Method: Using a systematic review method, this study searches for literature that matches the criteria in the PubMed electronic database and the wiley online library. There are 644 samples (290 samples of the MISS approach and 354 samples of the open approach) from seven articles that match the criteria that we have determined. Next, we extract data from our entire sample to find out the advantages of the MISS approach.                       Results: The MISS approach provides advantages in intraoperative (reduced operating time and blood loss) and early postoperative (reduced VAS score and hospitalization). In addition, the MISS approach also has advantages in the form of: minimal CSA, low transfusion requirements, and has a good ODI score. After more than one year of follow-up, the miss approach had the same neurologic recovery and risk of complications as the open approach. Conclusion: A minimally invasive approach provides an advantageous and safer to the management of all types of thoracolumbar fractures. Keywords: Advantage, Minimally Invasive, Open Surgery, Thoracolumbar Injuries  ]]>
<![CDATA[EVALUASI SURVIVIN DAN MAMMALIAN TARGET OF RAPAMYCIN COMPLEX-1 SERTA KORELASINYA PADA AKNE VULGARIS ]]>
<![CDATA[Mirna Marhami Iskandar]]>;
<![CDATA[Sri Yusfinah Masfah Hanum]]>;
<![CDATA[Erny Kusdiah]]>;
<![CDATA[Rima Rahmi Putri Harahap]]>;
<![CDATA[Jelica Oktaviani]]>
<![CDATA[ Jambi Medical Journal : Jurnal Kedokteran dan Kesehatan Vol. 11 No. 1 (2023): Jambi Medical Journal: Jurnal Kedokteran dan Kesehatan ]]>
Publisher : <![CDATA[FAKULTAS KEDOKTERAN DAN ILMU KESEHATAN UNIVERSITAS JAMBI ]]>
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DOI: 10.22437/jmj.v11i1.21121
<![CDATA[Background: Survivin is a member of the apoptosis inhibitory protein family, a protein molecule important for the regulation of mitosis and inhibition of apoptosis and also plays a role in certain physiological processes and pathological conditions such as carcinogenesis in human cells/organs. Several studies have shown that survivin plays a role in the pathogenesis of acne vulgaris and post-inflammatory acne scarring. Mammalian target of rapamycin complex-1 (mTORC1) is a regulator of cell growth, proliferation and metabolic homeostasis, and mTORC1 signaling regulates survivin via the kinase pathway. Objectives: This study aimed to assess the correlation of survivin levels with mTORC1 and the severity of acne vulgaris. Methods: This research was a cross-sectional study. Venous blood samples of mild, moderate, and severe AV patients were 20 people each, ELISA examination was performed. Result: The results showed that serum levels of survivin and mTORC1 had a correlation with the severity of AV (p<0.05), while the correlation between survivin and mTORC1 was not significant (p>0.05). Conclussion: This study proves that increased survivin and mTORC1 are associated with increased severity of acne vulgaris, but the relationship between survivin and mTORC1 needs further investigation. Key words: survivin, mammalian target of rapamycin complex-1, akne vulgaris]]>
<![CDATA[CORRELATION OF LYMPHOCYTE-MONOCYTE RATIO AND MORTALITY OF COVID-19 INTENSIVE CARE UNIT PATIENTS: PRELIMINARY STUDY ]]>
<![CDATA[Muhammad Fadhil Naufal]]>;
<![CDATA[Ade Susanti]]>;
<![CDATA[Fairuz Quzwain]]>
<![CDATA[ Jambi Medical Journal : Jurnal Kedokteran dan Kesehatan Vol. 11 No. 1 (2023): Jambi Medical Journal: Jurnal Kedokteran dan Kesehatan ]]>
Publisher : <![CDATA[FAKULTAS KEDOKTERAN DAN ILMU KESEHATAN UNIVERSITAS JAMBI ]]>
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DOI: 10.22437/jmj.v11i1.21163
<![CDATA[Background: The world faces a pandemic caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-Cov-2). Because of the limitations as a developing country, Indonesia needs to do its activities efficiently in time, money, and human resource. This research aims to accurately determine a concrete mortality predictor to predict the patients' mortality. One of the mortality predictors is the lymphocyte-monocyte ratio (LMR). Method: This research is observational analytic research using a cross-sectional study method. Data obtained from the Medical Record & Casemix Room of RSUD Raden Mattaher. Results: Out of 115 samples, most patients were male (65 patients). The patients' age group was mainly younger than 65 (79%). The most common comorbidity was diabetes mellitus (43 patients). The correlation between LMR and mortality rate to be weak with the following results: Pearson coefficient(p=0.045), gamma coefficient (P=0.325), Somers' D test (P=0.167), odds ratio (1.833), AUC (58%), specificity (58%), sensitivity (56%), and intersection point (1,79). Conclusions: There is a weak correlation between LMR and the mortality rate of COVID-19 patients in RSUD Raden Mattaher. Keywords: Characteristics of COVID-19 patients, Comorbidity of COVID-19 patients, LMR (Lymphocyte-monocyte ratio), a Mortality rate of COVID-19 patients]]>
<![CDATA[CASE REPORT: PHARINGEAL TUBERCULOSIS WITH MILLIARY TUBERCULOSIS ]]>
<![CDATA[Desvita Sari]]>;
<![CDATA[Mujahidah]]>;
<![CDATA[Subakir]]>;
<![CDATA[Maria Estela Carolina]]>
<![CDATA[ Jambi Medical Journal : Jurnal Kedokteran dan Kesehatan Vol. 11 No. 1 (2023): Jambi Medical Journal: Jurnal Kedokteran dan Kesehatan ]]>
Publisher : <![CDATA[FAKULTAS KEDOKTERAN DAN ILMU KESEHATAN UNIVERSITAS JAMBI ]]>
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DOI: 10.22437/jmj.v11i1.21444
<![CDATA[Background: Tuberculosis (TB) based on its manifestations is divided into two, pulmonary and extra pulmonary. Extrapulmonary TB can be miliary TB and pharyngeal TB. Miliary TB is spread by hematogenous spread to several organs. The diagnosis of extrapulmonary TB takes a long time, an accurate examination can determine extrapulmonary TB infection. Case Presentation: A 47-year-old man complained of recurrent pharyngitis and with symptoms of the respiratory system. Physical examination revealed white granulomatous lesions of the pharyngeal mucosa. The results of the tissue biopsy were performed with Ziehl Neelsen staining. The chest x-ray showed miliary tuberculosis. Diagnostic confirmation using sputum and tissue culture on Lowenstein Jensen medium, MPT64, and niacin paper strip test. Gene Xpert results detected Mycobacterium TB and Rifampicin resistance. Antituberculosis is given for four months. Conclusion: Physical examination of the throat revealed granulomatous inflammation and chest X-ray revealed miliary tuberculosis. The results of sputum and tissue culture on Lowenstein Jensen medium, MPT64, and paper strip test for niacin showed positive TB. Keywords: Pharyngeal tuberculosis, miliary tuberculosis, extrapulmonary tuberculosis.]]>
<![CDATA[PEMANFAATAN TEKNOLOGI INFORMASI BERBASIS WEBSITE DAN ANDROID SEBAGAI MEDIA PELAPORAN DAN PROMOSI ANTINARKOBA : LITERATURE REVIEW ]]>
<![CDATA[Akbar Suseno]]>;
<![CDATA[Sukihananto]]>
<![CDATA[ Jambi Medical Journal : Jurnal Kedokteran dan Kesehatan Vol. 11 No. 1 (2023): Jambi Medical Journal: Jurnal Kedokteran dan Kesehatan ]]>
Publisher : <![CDATA[FAKULTAS KEDOKTERAN DAN ILMU KESEHATAN UNIVERSITAS JAMBI ]]>
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DOI: 10.22437/jmj.v11i1.21943
<![CDATA[Background :Information technology is needed in today's era to support the dissemination of certain information. Utilization of website and android-based information technology can be used for media reporting and health promotion facilities. Objective: This study aims to analyze and design website and android-based information technology as a medium for reporting and promoting drugs at the Recipient Institution of Compulsory Reporting (IPWL) at the Regional Hospital of Jambi Province. Method : This study uses a literature review method. Result: This research resulted in website collaboration technology with android to create mobile applications in providing drug promotion (education) to the public about the dangers of drugs, and reporting data for IPWL officers. Conclusion: The results of this study are intended to assist parties involved in the drug eradication movement in Indonesia. Keywords: Reporting, Promotion, IPWL, Website, Android, Information Technology]]>
<![CDATA[DETECTION OF MecC GENE OF METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS ISOLATES AT JAMBI CITY HOSPITALS ]]>
<![CDATA[Humaryanto]]>;
<![CDATA[Fairuz]]>;
<![CDATA[Hanina]]>
<![CDATA[ Jambi Medical Journal : Jurnal Kedokteran dan Kesehatan Vol. 11 No. 1 (2023): Jambi Medical Journal: Jurnal Kedokteran dan Kesehatan ]]>
Publisher : <![CDATA[FAKULTAS KEDOKTERAN DAN ILMU KESEHATAN UNIVERSITAS JAMBI ]]>
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DOI: 10.22437/jmj.v11i1.23910
<![CDATA[Background: Methicillin Resistant Staphylococcus aureus (MRSA) has a low-affinity to penicillinbinding protein (PBP) in B1subclass, and is often known as PBP2a or PBP2, characterized by the presence of mecA gene. Further research found MRSA isolates that did not contain the mecA gene. They have mecA homolog gene (mecALGA251) which has similarity with the classic mecA gene, then named the mecC gene. The discovery of MRSA mecC in humans still low in prevalence.Objective: This study aimed to detect mecC gene in MRSA isolates at hospitals in Jambi.Method: This study was a descriptive study conducted in the Biomedical and Biomolecular Laboratoryof Faculty of Medicine and Health Sciences, Jambi University.Results: A total of 117 clinical specimens in the forms of purulent wound swabs of the inpatients athospitals in Jambi City has been cultured on the MSA agar. Then yellowish samples (43 isolates) were screened for susceptibity of cefoxitin (30 µg) by disc / diffusion test and the presence of mecA, femB and mecC genes by conventional PCR. There were 22 (51.16%) samples contained mecA, 2 (4.65%) samples had also femB gen, 1 (2.32%) samples contained femB gene only and none contained the mecC gene.Conclusion: There was no mecC gene had been found in MRSA isolates in Jambi.Keywords: PCR, MRSA, MecC, MecA, FemB]]>
