cover
Article Per Year (5 Year)
All
Home Page
OAI Link
Editorial Team
Contact
Reviewer
Google Scholar
Contact Name
-
Contact Email
-
Phone
-
Journal Mail Official
-
Editorial Address
-
Location
Kota denpasar,
Bali
INDONESIA
BALI MEDICAL JOURNAL (BMJ)
Published by Universitas Udayana
ISSN : -     EISSN : -     DOI : -
Core Subject : Health,
Medicine & Pharmacology
Bali Medical Journal (BMJ), P-ISSN 2089-1180, E-ISSN 2302-2914 is an international and peer-reviewed journal published quarterly in print and online by Sanglah General Hospital in collaboration to Indonesian Physician Forum and Indonesian College of Surgeon, Bali-Indonesia which was founded in 2011. The Journal aims to bridge and integrate the intellectual, methodological, and substantive diversity of medical scholarship, and to encourage a vigorous dialogue between medical scholars and practitioners. The Journal welcomes contributions which promote the exchange of ideas and rational discourse between practicing educators and medical researchers all over the world.
Arjuna Subject : -
Articles 179 Documents
 2   3   4   5   6 
IMMUNE RESPONSE AND COST ANALYSIS OF INTRADERMAL RABIES VACCINATION FOR POST-EXPOSURE PROPHYLAXIS REGIMEN IN HUMAN Budayanti, N. S.; Susilawathi, N. M.; Darwinata, A. E.; Dwija, I. B. P.; Fatmawati, N. D.; Wirasandhi, K.; Subrata, K.; Susilarini, N. K.; Wignall, F. S.; Sudewi, A. A. R.; Mahardika, and G. N. K.
BALI MEDICAL JOURNAL Vol 3 No 1 (2014)
Publisher : BALI MEDICAL JOURNAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (229.703 KB)

Abstract

Background The outbreak of rabies in human in Bali-Indonesia is causing an extraordinary pressure for the government in providing adequate doses of anti-rabies vaccine for post-exposure prophylaxis (PEP). Here, we directly compare the immune response and benefit of the intradermal (ID) protocol for rabies vaccine delivery with the intramuscular (IM) route. Methods: Sixty health workers who were willing to participate in this study have been randomly selected and grouped into ID, IM, and control groups, each with 20 volunteers. The Thai Red Cross ID- and Zangreb IM-protocols have been applied to the respective group. The sera of the volunteers were collected at day 0, week 1, week 3, week 4, month 3, month 6, month 9, and month 12 after the first vaccination. Anti-rabies virus IgG was detected using PlateliaTM Rabies II Kit (Bio-Rad). Results: Anti-rabies IgG could be detected in the ID-group at one week. The ID-vaccine delivery induced a slightly higher maximum antibody titer compared to IM, though not statistically significant (p>0.05). ID vaccination caused less adverse reactions and produces longer lasting protective immune response. Cost minimization analysis (CMA) on the provincial and national PEP data in 2009-2011 shows that the ID-delivery will reduce the total cost for a completed regimen by USD 28.5, and would have saved the Indonesian government budget approximately USD 3.6 and 4.3 million for complete regimens in Bali and Indonesia, respectively. Conclusion: The ID administration of anti-rabies vaccine induces a similar immune response compared to that of intramuscular injection. It also produces longer lasting protective immune response. It offers additional advantages of potential net cost savings as well as decreasing the pressure on vaccine availability due to the high number of dog bite cases.
Relative Humidity of 40% Inhibiting the Increase of Pulse Rate, Body Temperature, and Blood Lactic Acid During Exercise Sandi, N.; Adiputra, N.; Pangkahila, A.; Adiatmika, P. G.
BALI MEDICAL JOURNAL Vol 5 No 2 (2016)
Publisher : BALI MEDICAL JOURNAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (262.613 KB)

Abstract

Background: Excessive sweating of the body is a reaction to decrease the heat caused by prolonged exercise at high relative humidity (RH). This situation may cause an increase in pulse rate (PR), body temperature (BT), and blood lactic acid (BLA) workout. Objective: This study aimed to prove that a RH of 40% better than a RH of 50% and 60% RH in inhibiting the increase of PR, BT, and BLA during exercise. Methods: The study was conducted on 54 samples randomly selected from the IKIP PGRI Bali students. The samples were divided into three groups, and each group was given cycling exercise with a load of 80 Watt for 2 x 30 minutes with rest between sets for five minutes. Group-1 of cycling at 40% of RH, Group-2 at a RH of 50%, and the Group-3 at a RH of 60%. Data PR, BT, and BLA taken before and during exercise. The mean difference between groups before and during exercise were analyzed by One-way Anova and a further test used Least Significant Difference (LSD). Significance used was ? = 0.05. Results: The mean of PR during exercise was significantly different between groups with p = 0.045, the mean of BT during exercises was significantly different between groups with p = 0.006, and the mean of BLA during exercises was significantly different between groups with p = 0.005 (p
THERE IS NO DIFFERENCE OF SURGICAL SITE INFECTION BETWEEN SINGLE-DOSE AND MULTIPLE-DOSE OF PROPHYLAXIS ANTIBIOTIC IN OPEN APPENDECTOMY OF NON-PERFORATED ACUTE APPENDICITIS Tiono, B.G.; Sudartana, K.; Widiana, R.
BALI MEDICAL JOURNAL Volume 1, Number 3, September-December 2012
Publisher : BALI MEDICAL JOURNAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (63.801 KB)

Abstract

Objective: Acute appendicitis is the most common surgical emergency encountered compared with other non-traumatic acute abdomens. Sanglah General Hospital recorded there were 470 cases of acute appendicitis in the year 2006. This study  aims to determine the effectiveness of a single-dose antibiotic prophylaxis in prevention of surgical site infection in open appendectomy of non-perforated acute appendicitis. Method: A single blind randomized controlled trial in 110 non-perforated acute appendicitis patients that underwent open appendectomy at Sanglah General Hospital emergency operating theatre from April to June 2012 was conducted. Cefazolin 1 g and Metronidazole 500 mg were administered intravenously prior operation. Samples were divided into two groups by permuted block. Following operation, the single-dose group was administered placebo, while the multiple-dose group received two additional doses of antibiotics. Surgical site infection (SSI) of both groups in every week for one month was evaluated. Surgical site infection was determined based on Hulton’s criteria. Risk of surgical site infection of both groups was analyzed with Relative Risk (chi-square). Results: In the single-dose group 49.1% were males and 50.9% were females with a mean age of 28.71 years old, and in the multiple-dose group 40% were males and 60% were females with a mean age of 29.07 years old. Risk of SSI in single-dose group was 7.3% and multiple-dose group was 5.5% with Relative Risk (RR) = 1.33% (95% CI RR: 0.31-5.68, p= 1.000). Conclusion: There is no difference of SSI risk between single and multiple-dose antibiotic prophylaxisinopen appendectomy of non-perforated acute appendicitis.
ROLE OF MELATONIN IN EXPRESSION OF MALONDIALDEHYDE ON MICROGLIA CELLS OF RAT INDUCED HEAD INJURY Nasution, Khairul Iksan
BALI MEDICAL JOURNAL Vol 4 No 2 (2015)
Publisher : BALI MEDICAL JOURNAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (266.193 KB)

Abstract

Background: brain injury is condition that harm human life. This study examines the application of melatonin in reducing oxidant status and barriers to the formation of cerebral edema in a rat brain injury model. The main purpose of this study is to prove the role of melatonin on the expression of Malondialdehyde (MDA) and histological injury in a rat head injury model. Methods: This study was a randomized experimental posttest only control group design. This experimental was carried out on male Sprague Dawley strain Rattus novergicus, aged of 10-12 weeks, and weight of 300 g. Rat brain injury model was performed based on Marmarou (1994).1 Histology were observed using hematoxilen-eosin staining and immunohistochemistry, MDA was assessed using antibodies specific to each MDA protein. Observation and calculation of immunohistochemistry studies were also performed. Results: In this study, histological observation area covers an area of bleeding, number of immune-competent cells and the diameter of the arteries. Histology observation results showed that there is a significant reduction in diameter of arterial blood vessels of the brain injury tissue. Immunohisto-chemistry results showed that there is a significant reduction of MDA expression amount microglia cells of brain injury tissue. Conclusion: From this study, it can be concluded that Melatonin is a potent hydrogen peroxide scavenger that reduce the production of MDA.
Initial Clinical Findings as a Predictor of Abnormal Scan on Minor Head Injury Patients at Sanglah General Hospital, Bali-Indonesia -, Ade-Chandra; Niryana, W; Golden, N
BALI MEDICAL JOURNAL Volume 1, Number 2, May-August 2012
Publisher : BALI MEDICAL JOURNAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (55.083 KB)

Abstract

Objective: Minor Head Injury (MHI) patients should not cause severe sequelae. In fact, many studies had reported that some MHI patients had abnormal scan, clinical deteoritation, and many of them have had neurosurgical intervention. This study analyzed correlations between clinical signs with abnormal scan, clinical deteoritation and surgery intervention on minor head injury patients. Methods: A series of 364 MHI patients were prospectively enrolled in this study. In all cases clinical data were collected and a CT Scan was obtained. The relationship between clinical findings (loss of conciousness, amnesia, seizure, vomiting, headache, cepalhameatome, skull fracture, age more than 60 years),were identified as independent risk factors in corelations to abnormal scan, clinical deteoritation and surgery intervention using bivariate and logistic regresion multivariate analitycs with 95 % CI. Results: the incidence of abnormal scan was 13.8% (48 patients), 3.3% (12 patients) with clinical deteoritation, and incidence of surgery intervention was 3.8% (14 patiens).  Lost of conciousness, amnesia, cepalhematoma, skull fracture, and age more than 60 years old  are independent variabels had statisiticly significant with abnormal scan. Amnesia, cepalhematome, skull fracture are independent variables which had statisitc significantly with  clinical deterioritation and surgical intervention. Conclusions: Clinical variables which had statistic significanly can be used as predictors of abnormal scan, clinical deteoritation, and surgical intervension. Avoiding systematic CT Scan indication implies a rate of misdiagnosis, but liberal scan can be increasing the cost of patients.
POLYMORPHISM OF VASCULAR ENDOTHELIAL GROWTH FACTOR REGIO PROMOTER C(-634)G AS A RISK FACTOR OF BALINESE TYPE-2 DIABETIC RETINOPATHY Mas-Putrawati, A. A.; Bakta, M.; Suastika, K.; Muhiddin, H. S. Habiba; Niti Susila, N. K.
BALI MEDICAL JOURNAL Vol 4 No 2 (2015)
Publisher : BALI MEDICAL JOURNAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (330.03 KB)

Abstract

Background: Diabetic retinopathy (DR) is one of the complications on diabetic mellitus (DM) patient as a micro vascular retina disorder which caused by a long term of hyperglycemia. This is one of the blindness causes in the world. This research aims to find out Polymorphism of VEGFC(-634)G gene as a risk factor of DR on the Balinese with DM type-2 (DMT2). Method: This study is applying two designs, analytical cross sectional and case control. The case is DMT2 patient with DR(+), DMT2 without DR as control. The sequencing technique was performed to evaluate polymorphism and plasma VEGF levels were determined by ELISA. Results: Cross sectional study (hospital based) came out with quite high number of DR, 57 people of 97 study samples. This study shows the existence of genetic variation on Gen VEGF C(-634)G, with most often genotype of CG (51.5%). Polymorphism C(-634)G as the risk factor of DR (OR=1.815 CI-95%= 1.077-3.057, p=0.025), and high level of VEGF were also significant (QR=3.75 , CI-95% 1.34-10.20, p=0.008). VEGF level with genotype of CG, CC and GG, not found any difference (p=0.245). Logistic regression shows that the most influential variable as the risk factor of DR is VEGF level (p= 0.007), polymorphism gen VEGF C(-634)G (p=0.022) and systolic blood pressure (p=0.023). Conclusions: Polymorphism of VEGF C(-634)G gene and high level of VEGF as the risk factor of DR, and can be used as a reference in handling early stage of DR patient to prevent blindness.
PHACOEMULSIFICATION AND SUTURELESS LARGE-INCISION MANUAL CATARACT EXTRACTION CHANGE CORNEAL SENSIBILITY Anom-Supradnya, I G. N.; Jayanegara, W. G.; Sugiana, I G. N. M.; Raka-Widiana, and I G.
BALI MEDICAL JOURNAL Vol 2 No 3 (2013): Vol.2, No.3, September-December 2013
Publisher : BALI MEDICAL JOURNAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (281.086 KB)

Abstract

Background: Cataract is the leading cause of blindness worldwide, with surgery as a definitive therapy. Incisions may damage the underlying tissue, including loss of corneal sensibility. The purpose of this study was to determine differences in corneal sensibility decreased in patients after phacoemulsification and SLIMCE. Method: This study was a randomized clinical trial assessing changes of corneal sensibility in immature senile cataract patients after phacoemulsification and SLIMCE at Sanglah and Indera Hospital Denpasar, Bali-Indonesia from March to August 2013.  Surgeons and examiners are experienced ophthalmologists. Examiner did not know the initial data subjects. Preoperative assessment of corneal sensibility on the first, eighth, and fifteenth days were assessed postoperative using Cochet-Bonnet aesthesiometer. Statistical analysis was performed by applying mean difference of two independent groups test with repeated measures of multiple comparisons (ANOVA). Samples from each group were 17 eyes. Results: There were significant differences in corneal sensibility on the first day postoperative (33.2 mm), day 8 (-21.5 mm), day 15 (-11.8 mm) in both groups. Decrease in corneal sensibility in both groups was significant (p = 0.001). There was decreasing in corneal sensibility with SLIMCE technique in the first (21.8 mm) and eighth day (45.9 mm). Conclusion: In phacoemulsification technique, corneal sensibility was also decreased in the first (31.8mm) and eighth day (50.6 mm) but returned to preoperative values on day 15 in both groups. Decrease in corneal sensibility during follow-up period is influenced by cataract surgery technique (p = 0.017) and was higher in SLIMCE technique compared with phacoemulsification.
A Young Male with Spontaneous Ruptured Cerebral Arteriovenous Malformation (Case Report) Santos, Vitorino M.; Flores, Leandro P.; Barros, Isabella A.; Faria, Priscilla S.; Lamounier, Carolina P.; Casasanta, Renata A.
BALI MEDICAL JOURNAL Vol 5 No 1 (2016)
Publisher : BALI MEDICAL JOURNAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (327.265 KB)

Abstract

Background: Cerebral arteriovenous malformation (AVM) is considered a congenital condition characterized by arterial-venous connections in the absence of intermediate capillaries with circulatory and functional changes, inclusive on the cerebrospinal fluid (CSF) dynamics. Case: A previously healthy young man with abrupt onset of intense headache followed by incoercible vomiting and generalized tonic-clonic seizures. On admission, he was in Glasgow scale IV with respiratory gasping, signs of decerebration and anisocoric mydriasis, and right paresis. Computed tomography showed left intraparenchymal hematoma and intraventricular blood. The abnormal vessels and blood clots were removed by neurosurgery. In early postoperative phase a large cerebrospinal fluid leak developed, and was aspirated and further controlled. The patient had respiratory complications, including pulmonary infection by Pseudomonas. Conclusions: After longstanding hospitalization, he was referred to other medical institution and home care.
TRANS-ARTERIAL EMBOLIZATION WITH N-BUTYL CYANOACRYLATE GLUE FOR RENAL BLEEDING: Case Report Young, Benny
BALI MEDICAL JOURNAL Vol 3 No 2 (2014)
Publisher : BALI MEDICAL JOURNAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (312.127 KB)

Abstract

Background: The objectivity in management of renal bleeding is to preserve a significant renal parenchyma tissue and prevent associated morbidities like anemic shock or renal impairment from substantial nephron demise or obstructed uropathy. Trans-arterial embolization therapy by interventional radiology offers a high success rate with potential of reserving normal renal tissue. The selection material for renal arterial embolization largely depends on vasculature anatomy and endpoint of procedure. N-butyl cyanoacrylate glue in our experience is applied in lesion supplied by small size of end-artery.
Association of Epidermal Growth Factor Receptor (EGFR) with Tumor Location and Clinicopathological Aspect in Head and Neck Squamous Cell Carcinoma Nuratna, I Nyoman Diwiya Abdi; Wisesa, Ida Bagus Made Surya
BALI MEDICAL JOURNAL Vol 5 No 2 (2016)
Publisher : BALI MEDICAL JOURNAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (758.248 KB)

Abstract

Background: Head and neck squamous cell carcinoma (HNSCC) is the most common type of head and neck cancer. Most patients came with advanced disease which results in suboptimal treatment. EGFR is one of prognostic factors that play important role in HNSCC pathogenesis and progression. Unraveling the expression profile of EGFR in anterior and posterior HNSCC and its comparison would provide physician with better information regarding EGFR based treatment or its prognostic value. Methods: An observational cross sectional analytic study was conducted to compare EGFR expression between anterior and posterior HNSCC. The association between EGFR expressions with clinicopathological aspects (tumor stadium and histological grade) of HNSCC which analyzed separately. Baseline characteristic and each variable were first analyzed descriptively. Comparative analysis was conducted using Chi-Square and Fisher exact test with p value less than 0.05 was considered significant. Result: 48 samples were used in this study. Most of the subjects were elderly (83.2%), men (72.9%) and came with advanced disease (Clinical Stadium III-IV) (83.3%). Most of the subjects were EGFR (+) (93%). In anterior region group, low expression of EGFR was found in 6 patients (25%) and high expression in 18 patients (75%). Meanwhile in posterior region group we found low expression in 10 patients (41.7%) and 14 patients with high expression of EGFR (58.3%). We found no association between EFGR and HNSCC location (anterior or posterior) (p=0.221). Insignificant association also reported between EGFR expression with clinical stage of anterior (p=0.625) and posterior (p=0.283) HNSCC as well as histopathological grade of both location (p=0.33 for anterior group and p=0.371 for posterior group). Conclusion: We concluded that EGFR was diffusely expressed in HNSCC but there was no association between EGFR expression and clinicopathological characteristics and location of HNSCC.

Page 4 of 18 | Total Record : 179

 2   3   4   5   6 

Filter by Year

2012 2016


Reset
Filter By Issues
All Issue Vol 5 No 3 (2016) Vol 5 No 2 (2016) Vol 5 No 1 (2016) Vol 4 No 3 (2015) Vol 4 No 2 (2015) Vol 4 No 1 (2015) Vol 3 No 3 (2014) Vol 3 No 2 (2014) Vol 3 No 1 (2014) Vol 2 No 3 (2013): Vol.2, No.3, September-December 2013 Volume 2 Number 2, May-August 2013 Volume 2 Number 1, January-April 2013 Volume 1, Number 3, September-December 2012 Volume 1, Number 2, May-August 2012 Volume 1, Number 1, January-April 2012 More Issue