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Dental Journal (Majalah Kedokteran Gigi)
Published by Universitas Airlangga
ISSN : 19783728     EISSN : 24429740     DOI : -
Core Subject : Health,
Dentistry
The Dental Journal (Majalah Kedokteran Gigi) (e-ISSN:2442-9740; p-ISSN:1978-3728) is published by the Faculty of Dental Medicine, Universitas Airlangga. Its diciplinary focus is dental science and dental hygiene. The Dental Journal (Majalah Kedokteran Gigi) is published in English on a quarterly basis with each 50-60 page edition containing between nine and eleven scientific articles on research, study literature and case studies. Contributors to the Dental Journal (Majalah Kedokteran Gigi) included: dental researchers, dental practitioners, lecturers, and students drawn from Indonesia and a wide range of other countries.
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Articles 12 Documents
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Search results for , issue "Vol. 56 No. 3 (2023): September" : 12 Documents clear
Surface roughness assessment with fluoride varnish application: An in vitro study Anie Apriani; Silvia Naliani; Rudy Djuanda; Shania Hysan Teanindar; Jessica Quiteria Florenthe; Ferri Baharudin
Dental Journal Vol. 56 No. 3 (2023): September
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/j.djmkg.v56.i3.p154-159

Abstract

Background: The cause of cavities is initially due to roughness on the tooth surface, requiring fluoride varnish to prevent caries, as the varnish applies a fluoride compound to the tooth surface. Fluoride varnish reacts with the tooth enamel surface to form calcium fluoride and fluorapatite, thus making the enamel surface more resistant to demineralization and damage. Purpose: This study aims to compare the roughness of tooth enamel surfaces among three fluoride varnishes under acidic conditions. Methods: The research method uses three fluoride varnish materials: sodium fluoride 5% + tricalcium phosphate, calcium fluoride, and sodium fluoride 5% + casein phosphopeptide-amorphous calcium phosphate 2%. Samples of 81 teeth were divided into three groups (Group 1 without fluoride varnish application, Group 2 application of fluoride varnish with pH 3, and Group 3 application of fluoride varnish with pH 5). The teeth were tested before and after application of the varnishes using the scanning electron microscope and surface roughness tests. Results: The results showed a significant difference in the mean surface roughness of the enamel of the anterior deciduous teeth tested with fluoride varnish. The before and after comparisons in the pH 3 and pH 5 groups were very significant (p-value 0.000). The comparison results in each pH group after fluoride varnish administration showed no significant difference (pH 3 p-value 0.074 and pH 5 p-value 0.196). The tooth surfaces appear to be rougher after administration of an all-acid solution. Conclusion: There is a difference in surface roughness of primary teeth after being given fluoride varnish in low pH 3 immersion for 24 hours.
Amelogenin and alkaline phosphatase expression in ameloblast after saltwater fish consumption in pregnant mice (Mus musculus) Sandy Christiono; Seno Pradopo; I Ketut Sudiana; Islamy Rahma Hutami; Regilia Shinta Mayangsari; Yayun Siti Rochmah; Zurairah Ibrahim
Dental Journal Vol. 56 No. 3 (2023): September
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/j.djmkg.v56.i3.p166-171

Abstract

Background: The intricate process of tooth formation during embryonic development ensures sufficient nutrition for the growth of healthy dental tissues. Amelogenin and alkaline phosphatase (ALP) are serine proteinases secreted by the ameloblast during the transition and maturation phases of the amelogenesis process. Consumption of saltwater fish is predicted to increase the expression of amelogenin and ALP in ameloblast cells during tooth formation. Only now have the function of each gene, tooth-forming cells, and the proteins they produce in the biomolecular amelogenesis of tooth enamel, which began during prenatal development, been clarified. Purpose: This study aims to determine how saltwater fish powder affects the ability of mother mice to increase the expression of amelogenin and ALP in cell ameloblast. Methods: Using a completely randomized design, this study was experimental and aimed to examine the effects of sardine (Sardinella fimbriata), splendid ponyfish (Leiognathus splendens), and tuna (Euthynnus affinis) powder. As samples, twenty-four female mice (Mus musculus) were used. Two groups of mice were created: group 1 (2.14 mg/0.5 ml) and the control group. The expression of amelogenin and ALP was determined using immunohistochemistry (IHC) and t-test (p0.05). Results: Expression of ameloblast was significantly different between the treatment and control groups (p0.05). Conclusion: The consumption of saltwater fish reduces the amelogenin and ALP expressions of mouse fetal ameloblast cells during tooth development in vivo.
Closed reduction and drainage incision for the treatment of neglected and infected mandibular fractures Eddy Hermanto; Fanny Margaretha Laihad; Amelia Elizabeth Pranoto; Monika Elidasari; Ivan Tantra; Sarianoferni; Dian Widya Damayanti
Dental Journal Vol. 56 No. 3 (2023): September
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/j.djmkg.v56.i3.p197-201

Abstract

Background: Jaw fracture is the most common facial fracture in oral and maxillofacial bone and is usually caused by trauma. The fracture itself could lead to infection due to bone and tissue damage, which is the port of entry for microorganisms. Fracture-related infection (FRI) in the patient discussed in this study manifested as a submandibular abscess. The goals of fracture treatment were achieving the anatomic reduction of the fracture line and regaining acceptable occlusion. There are two methods for treating mandibular fractures: the closed method, also called conservative treatment, and the open method, which requires advanced surgery. Closed method treatment uses a maxillomandibular fixation (MMF) device in order to reduce and immobilize fracture fragments. Treatment of FRI should use a multidisciplinary approach to achieve an outstanding result, such as wound debridement, antimicrobial therapy, and implant retention. Purpose: The purpose of this article is to report a case of neglected mandibular fracture with a submandibular abscess, which was treated with a combination of the closed reduction method and incision drainage. Case: A 25-year-old female visited Nala Husada Hospital because of a submandibular abscess on the neglected mandibular fracture of the right parasymphysis and left corpus. Case management: The case was managed using an arch bar in the mandible and an eyelet in the maxilla while continuing with MMF and an extra oral drainage incision. Conclusion: Combination therapy (MMF and incision drainage) was needed to treat this case because of the occurrence of a submandibular abscess due to a neglected mandibular fracture.
The effect of nanoparticle tooth grafts on osteoblast stimulation in the first stages of the bone healing process in Wistar rats compared to the micro-tooth graft technique Ega Lucida Chandra Kumala; Malianawati Fauzia; Hana Salsabila Junivianti
Dental Journal Vol. 56 No. 3 (2023): September
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/j.djmkg.v56.i3.p184-188

Abstract

Background: The use of a bone graft in bone regeneration is challenging. Tooth graft material has been used as a bone graft alternative due to its similar composition of organic and inorganic materials close to the bone. Recently, nanotechnology has been used to improve bone graft quality. The osteoconduction rate in the defect area represents the bone graft quality. Purpose: This study aimed to compare the number of osteoblasts using nano-tooth grafts and micro-tooth grafts in Wistar rats. Methods: Wistar rats were divided into six groups: the negative control groups (examined on days 7 and 14), the micro-tooth graft groups (examined on days 7 and 14), and the nano-tooth graft groups (examined on days 7 and 14). The control group received nothing, the micro-tooth group received a micro-size tooth graft, and the nano-tooth graft group received a nano-size tooth graft on the injured femur. Histological observations of osteoblasts were carried out using a light microscope with 1000x magnification. Data were analyzed using one-way analysis of variance and least significant difference tests. Results: On day 7, the nano-tooth graft group showed a higher osteoblast number (11.75) than the micro-tooth graft group (7.5) (p = 0.039). There was no significant difference in the micro-tooth graft group compared to the control (p > 0.05). On day 14, the nano-tooth graft group showed a decrease in osteoblast number close to normal (control) (p > 0.05), while the micro-tooth graft group still experienced significant elevation. Conclusion: Nano-tooth grafts accelerate the stimulation of osteoblasts in the first stages of the healing process compared to micro-tooth grafts.
The characteristics of swelling and biodegradation tests of bovine amniotic membrane-hydroxyapatite biocomposite Titien Hary Agustantina; Elly Munadziroh; Anita Yuliati; Muhammad Riza Hafidz Bahtiar; Octarina; Rizki Fauziah Salma; Ajeng Putri Meyranti; Fathilah Abdul Razak
Dental Journal Vol. 56 No. 3 (2023): September
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/j.djmkg.v56.i3.p172-177

Abstract

Background: A good biocomposite is a structure that can provide opportunities for cells to adhere, proliferate, and differentiate. It is affected by the characteristics of a material. As bone tissue regeneration occurs, biomaterials must have a high swelling ability and low biodegradability. The high swelling capability will have a larger surface area that can support maximal cell attachment and proliferation on the biocomposite surface, which accelerates the regeneration process of bone defects. Purpose: The study aimed to analyze the characteristics of swelling and biodegradation of bovine amniotic membrane-hydroxyapatite (BAM-HA) biocomposite with various ratios. Methods: The BAM-HA biocomposite with a ratio of 30:70, 35:65, and 40:60 (w/w) was synthesized using a freeze-dry method. The swelling test was done by measuring the initial weight and final weight after being soaked in phosphate-buffered saline for 24 hours and the biodegradation test was done by measuring the initial weight and final weight after being soaked in simulated body fluid for seven days. Results: The swelling percentage of BAM-HA biocomposite at each ratio of 30:70, 35:65, and 40:60 (w/w) was 303.90%, 477.94%, and 574.19%. The biodegradation percentage of BAM-HA biocomposite at each ratio of 30:70, 35:65, and 40:60 was 9.43%, 11.05%, and 12.02%. Conclusion: The BAM-HA biocomposite with a ratio of 40:60 (w/w) has the highest swelling percentage while the 30:70 (w/w) ratio has the lowest percentage of biodegradation.
The compressive strength and static biodegradation rate of chitosan-gelatin limestone-based carbonate hydroxyapatite composite scaffold Devi Rianti; Alqomariyah Eka Purnamasari; Rifayinqa Ruyani Putri; Noor Zain Salsabilla; Faradillah; Elly Munadziroh; Titien Hary Agustantina; Asti Meizarini; Anita Yuliati; Ardiyansyah Syahrom
Dental Journal Vol. 56 No. 3 (2023): September
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/j.djmkg.v56.i3.p160-165

Abstract

Background: One of the main components in tissue engineering is the scaffold, which may serve as a medium to support cell and tissue growth. Scaffolds must have good compressive strength and controlled biodegradability to show biological activities while treating bone defects. This study uses Chitosan-gelatin (C–G) with good flexibility and elasticity and high-strength carbonate hydroxyapatite (CHA), which may be the ideal scaffold for tissue engineering. Purpose: To analyze the compressive strength and static biodegradation rate within various ratios of C–G and CHA (C–G:CHA) scaffold as a requirement for bone tissue engineering. Methods: The scaffold is synthesized from C–G:CHA with three ratio variations, which are 40:60, 30:70, and 20:80 (weight for weight [w/w]), made with a freeze-drying method. The compressive strengths are then tested. The biodegradation rate is tested by soaking the scaffold in simulated body fluid for 1, 3, 7, 14, and 21 days. Data are analyzed with a one-way ANOVA parametric test. Results: The compressive strength of each ratio of C–G:CHA scaffold 40:60 (w/w), 30:70 (w/w), and 20:80 (w/w), consecutively, are 4.2 Megapascals (MPa), 3.3 MPa, 2.2 MPa, and there are no significant differences with the p= 0.069 (p>0.05). The static biodegradation percentage after 21 days on each ratio variation of C–G:CHA scaffold 40:60 (w/w), 30:70 (w/w), and 20:80 (w/w) is 25.98%, 24.67%, and 20.64%. One-way ANOVA Welch test shows the result of the p-value as p<0.05. Conclusion: The compressive strength and static biodegradation of the C–G:CHA scaffold with ratio variations of 40:60 (w/w), 30:70 (w/w), and 20:80(w/w) fulfilled the requirements as a scaffold for bone tissue engineering.
Ovalbumin’s potential as a wound-healing medicament in tooth extraction socket by induction of cell proliferation through the ERK2 pathway in silico Sri Nabawiyati Nurul Makiyah; Sartika Puspita
Dental Journal Vol. 56 No. 3 (2023): September
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/j.djmkg.v56.i3.p144-153

Abstract

Background: The trend of studies on dental medicaments is increasing rapidly. Antibacterial or anti-inflammatory activity is most frequently studied. Ovalbumin is one of the proteins whose benefits have been studied, but these benefits are still limited because of ovalbumin’s potential for proliferative bioactivity. Purpose: The aim of this study is to examine ovalbumin’s potential as a woundhealing medicament through molecular docking analysis on a protein related to the extracellular signal-regulated kinases/mitogenactivated protein kinase (ERK/MAPK) signaling pathway. Methods: Ovalbumin was hydrolyzed through BIOPEP-UWM (The BIOPEPUWM™ database of bioactive peptides). Protein target and interaction were predicted using Similarity Ensemble Approach target prediction webserver, SuperPred webserver, STRING webserver, and Cytoscape version 3.9.1. Selected fragments were docked using Autodock Vina in PyRx 0.8 with Tukey’s multiple comparison test and Biovia Discovery Studio version 19.1.0.18287 for visualization. Results: This study found that ovalbumin has the potential to positively regulate cell proliferation, angiogenesis, and fibroblast growth factor production. Six of the 131 fragments of ovalbumin could interact with 73 proteins, and the 20 proteins with the highest probability and score of betweenness centrality showed potential for bioactivity. Five fragments and povidone-iodine interacted inside the Adenosine triphosphate (ATP) phosphorylation site of ERK2, whereas fragment 1 (F1) and glycerin interacted outside the site. F1 could decrease the binding energy required for adenosine 5′-[,-methylene]triphosphate or an ATP-analogue chemical compound to interact with ERK2 compared to the control, with a score that was not significant. Conclusion: Ovalbumin has the potential to induce cell proliferation by affecting ERK2-ligand interactions.
Dental traumatic injuries during the COVID-19 pandemic: A retrospective study Mehmet Veysel Kotanli; Mehmet Emin Doğan; Sedef Kotanli; Mehmet Sinan Doğan
Dental Journal Vol. 56 No. 3 (2023): September
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/j.djmkg.v56.i3.p139-143

Abstract

Background: Although dental trauma has been reported at various frequencies worldwide, as far as we know there are few data regarding the frequency of dental trauma during the pandemic period. Purpose: This study aims to retrospectively evaluate the data of pediatric patients who were admitted to the Department of Pedodontics in a university hospital due to dental trauma during the COVID-19 pandemic. Methods: Between April 2020 and December 2020, the clinical records regarding admissions to the Harran University Faculty of Dentistry Pedodontics clinic due to dental trauma were examined. The age and gender of the patient, type of trauma, teeth affected by the trauma, and treatment methods applied after the trauma were recorded. The data obtained were analyzed using the independent sample t-test for intergroup comparisons and Pearson chi-square test for categorical variables with the help of Statistical Package for the Social Sciences version 23.0. Results: The data of 43 patients (27 males and 16 females) aged between 1–13 years (mean age: 9.13±3.20) who were admitted to the clinic with trauma complaints during an eight-month period were evaluated. It was determined that the most common trauma types in the pandemic period were simple crown fracture (25.6%) and subluxation/lateral luxation (23.3%). During the pandemic, 34.9% of all cases were “falling at home”, while “falling at school” was 14.0% (using the Pearson chi-square test). Conclusion: The COVID-19 pandemic period has affected many aspects of social life as well as the number of patients who were admitted for dental trauma and the causes of trauma. Multicenter studies are needed for more accurate results.
Oral field cancerization: Genetic profiling for a prevention strategy for oral potentially malignant disorders Karlina Puspasari; Togu Andrie Simon Pasaribu; Meircurius Dwi Condro Surboyo; Nurina Febriyanti Ayuningtyas; Arvind Babu Rajendra Santosh; Diah Savitri Ernawati
Dental Journal Vol. 56 No. 3 (2023): September
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/j.djmkg.v56.i3.p189-196

Abstract

Background: Oral cancer therapy, such as radiation or surgical treatment, has pernicious long-term effects that patients suffer throughout their life, the disability being considerable with delayed diagnosis. It is well known that many oral cancers develop from oral potentially malignant disorders (OPMDs). Patients diagnosed with OPMDs may have an increased risk of developing cancer anywhere in the oral cavity. Early detection and intervention could be essential prevention strategies to inhibit oral cancer progression. OPMDs may not immediately develop into carcinoma. However, this condition provides a “field” of specific abnormalities wherein evolving altered genetic cells can be explained with the “field cancerization” concept. Purpose: This review aims to describe the “field cancerization” concept in oral cancer and OPMD, which is expected to contribute to a better clinical management strategy for oral cancer prevention. Review: “Oral field cancerization” describes oral cancers that develop in multifocal areas of pre-cancerous changes. It can be found as histologically abnormal tissue surrounding the tumor, suggesting that oral cancer often consists of multiple independent lesions. Conclusion: The oral field cancerization concept should prompt healthcare professionals to remind their patients that frequent oral examination with histological studies and molecular testing is mandatory for those at high risk of developing malignancies.
The early detection of tongue cancer with the etiology of mechanical trauma Aris Setyawan; Zhavira Dwiyanti Anang; Rizki Nurida Rahmawati; Winda Kumalasari; Alfi Dian Uly Noor; Rima Talitha Yulianti
Dental Journal Vol. 56 No. 3 (2023): September
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/j.djmkg.v56.i3.p208-212

Abstract

Background: Oral squamous cell carcinoma (OSCC) occurs in approximately 95% of people older than 40 years; usually, it is diagnosed at the age of 60 years. The etiology of OSCC is multifactorial. Chronic mechanical trauma due to sharp teeth has also been suggested as an etiology of oral squamous of the tongue. Purpose: This case report aimed to describe the etiology of OSCC resulting from mechanical trauma and to prevent further metastasis by correctly diagnosing the lesion earlier. Case: A 49-year-old female patient presented with painful and swollen stomatitis two months ago. No submandibular lymph nodes were palpable. An indurated ulceration and sharp teeth on the right region of the jaw were obtained from the intraoral examination. Malignancy was concluded from Histopathology Examination (HPE) and Magnetic Resonance Imaging (MRI) radiography results. Case Management: Multiple extractions were chosen to eliminate the etiology of mechanical trauma due to sharp teeth, and the patient underwent hemiglossectomy with the keyhole method. Postoperative, the histopathology examination revealed an OSCC of the tongue. The patient is currently in the second cycle of chemotherapy by hematologist-oncologists. Conclusion: The early appropriate diagnosis of a tongue ulcer can prevent metastasis, decrease morbidity, and increase quality of life.

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