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All Journal Journal of Tropical Life Science : International Journal of Theoretical, Experimental, and Applied Life Sciences International Journal of Natural Science and Engineering Jurnal Mitra Kesehatan Makara Journal of Science
Amelia, Ria
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Agriculture, Biological Sciences & Forestry Chemistry Engineering Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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Journal : International Journal of Natural Science and Engineering

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FORMULATION AND PHYSICAL CHARACTERIZATION OF BLACK SOYBEAN (Glycine Max L.) VARIETY OF DETAM II TABLETS WITH DRY GRANULATION METHOD Amelia, Ria
International Journal of Natural Science and Engineering Vol 5, No 1 (2021)
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23887/ijnse.v5i1.33441

Abstract

Black Soybeans (Glycine max L.)  Detam II varieties  have a higher protein content than other varieties. The high protein content in soybeans (Glycine max L.) is directly proportional to the levels of flavonoid compounds. Flavonoid compounds have been known to have potential as antioxidant compounds that can be beneficial for health. This study aims to obtain a tablet formulation of black soybean (Glycine max L.) detam II varieties . The research was conducted from February to October 2020 at the Pharmaceutical Technology Laboratory STIKes Mitra Keluarga. Preparation of black soybean (Glycine max L.) tablet of detam II variety by slugging method. Detam II black soybean tablets (Glycine max L.) were made into 5 formulas with 250 mg black soybean powder (Glycine max L.) content of detam II varieties in each formula. the differentiated variable is the tablet excipient compound in each formula. Evaluation of black soybean (Glycine max L.) tablet granules of detam II variety by testing water content,compressibility, flow time, angle of rest and tablet evaluation by testing organoleptic, weight, hardness, brittleness and disintegration time. The results showed that a formula  3, 4 and 5 are the recommended formulations for the manufacture of black soybean tablets (Glycine max L.) detam II varieties even though all formula ( F1-F5)  were below the friability value requirements due to several factors. Gelatin excipient and PVP K30 for the manufacture of black soybean tablets (Glycine max L.) detam II varieties are the best choices as tablet fillers.
Co-Authors Arief Budiman Astiti, Adam Cindiati, Maya Dwi Umi Siswanti, Dwi Umi Eko Agus Suyono Eko Agus Suyono Erfianti, Tia Hardianto, Muhammad Andhi Kurnianto, Dedy Luhulima, Danny Maggandari, Revata Maghfiroh, Khusnul Qonita Mardyansah, Deviko Natalia, Fitri Nurafifah, Istini Putri, Renata Adaranyssa Egistha Qonita Maghfiroh, Khusnul Ramadhanti, Moudy Ryan Sadewo, Brilian Sadewo, Brilian Ryan Siti Ferniah, Rejeki