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UJI AKTIVITAS ANTIBAKTERI GEL EKSTRAK ETANOL DAUN ANGSANA (Pterocarpus indicus Willd.) TERHADAP BAKTERI Staphylococcus aureus Nelly Suryani Djamain; Vivi Anggia; Nia Fachrunisa
Jurnal Insan Farmasi Indonesia Vol 3 No 1 (2020): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v3i1.488

Abstract

Angsana leaves (Pterocarpus indicus Willd.) contain flavonoids, saponins, tannins, alkaloids, glycosides, triterpenoids, and steroids can be used as an active substances that formulated into antibacterial formulation gel. In this study, ethanolic extracts of Angsana leaves are formulated into gel form to optimize the antibacterial activity from the extracts. The purpose of this study belongs to determine the differences antibacterial activity of ethanolic extracts of Angsana leaves before and after being formulated into gel form. Antibacterial activity test was determined by using disc diffusion method due to Kirby-Bauer method. Based on the results, it showed that formulation contains 0.09 mg extract formed 8 mm inhibition zone and 9 mg extract without formulation formed 16 mm inhibition zone. By comparing the amount of extracts to the inhibitory zone, it is known that extract which formulated into a gel form has greater activity than extract without formulated.
Pemberian Informasi Obat Pasien Dengan Resep Antibiotik dan Penyediaan Antibiotik Tanpa Resep di Tangerang Selatan: Providing Drug Information to Patients with Prescribing Antibiotics and Provision of Antibiotics without Prescription in South Tangerang Yardi Saibi; Nelly Suryani; Suci Ahda Novitri; Delina Hasan; Vidia Arlaini Anwar
Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal) Vol. 6 No. 2 (2020): (October 2020)
Publisher : Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (428.448 KB) | DOI: 10.22487/j24428744.2020.v6.i2.15051

Abstract

A pharmacy is a place where pharmacists do their pharmaceutical work, serving directly and responsibly for patients who need their professional services. One form of direct service is the provision of drug information and counseling. The purpose of this study was to describe the drug information services provided by pharmaceutical personnel in the South Tangerang area pharmacy for patients who redeemed prescriptions using antibiotics. Patient simulation method was used to collect data to 100 pharmacies that were randomly selected based on data in the city health office. Recommendations were obtained from the South Tangerang branch of the Indonesian Pharmacists Association while ethical clearance was obtained from the ethical committee of the Faculty of Medicine, University of Indonesia. The results of this study indicate that 85% percent of pharmaceutical personnel who provide drug information for simulated patients are non-pharmacists. The most widely conveyed drug information items were the frequency of drug use delivered by 82% of pharmacists, received by the intended use (61%) and time of use (44%). Not related to pharmacy officers who submit the following information: drug interactions and ways to prevent them, side effects of drugs and how to prevent them; food and drinks that must be avoided as well as how to store drugs. As many as 49% of pharmacists provide additional antibiotics requested by patients without a prescription. Drug information points provided by pharmacy staff specifically by pharmacist had not been maximally delivered.
Uji Stabilitas Spironolakton Terhadap Perubahan pH dengan Menggunakan Kromatografi Cair Kinerja Tinggi (KCKT) Nelly Suryani; Yardi Supandi; Ririn Astri Sabdowati
Jurnal Farmasi Indonesia Vol 16 No 1 (2019): Jurnal Farmasi Indonesia
Publisher : Fakultas Farmasi Universitas Setia Budi

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (780.444 KB) | DOI: 10.31001/jfi.v16i1.450

Abstract

Spironolactone is an aldosterone diuretic antagonist for hypertension. In practice spironolactone is sometimes combined with other drugs, and in unconscious patients the drug must use a feeding tube and be susceptible to instability. The object of this study was to see the effect of pH changes on spironolactone tablets which were crushed and suspended in water. The method of measuring spironolactone levels using High Performance Liquid Chromatography based on methods in the United State Pharmacopeia. Spironolactone suspension was made at pH 3, 5, 7, and 9 with sampling time in minutes 0, 15, 30, 45, and 60. The results showed that the level of spironolactone at pH 3 was ≤ 0%, pH 5 was 74% - 100%, at pH 7 it was in the range of 27% - 61%, and at pH 9 was 38% - 54%. This explains that percent of spironolactone at pH 3.7, and 9 at all sampling times did not match the minimum therapeutic level in the monograph. Only at pH 5 does the level of spironolactone still match the levels specified in the monograph. In this study it can be concluded that changes in pH can significantly reduce spironolactone levels in suspension.
UJI VIABILITAS MIKROENKAPSULASI Lactobacillus casei MENGGUNAKAN MATRIK NATRIUM ALGINAT Nelly Suryani; Ofa Suzanti Betha; Qurry Mawaddana
JFL : Jurnal Farmasi Lampung Vol. 8 No. 1 (2019): JFL: Jurnal Farmasi Lampung
Publisher : Fakultas MIPA Universitas Tulang Bawang Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (318.425 KB) | DOI: 10.37090/jfl.v8i1.80

Abstract

Lactobacillus casei is a species that is often used as a probiotic but is not resistant to very acidic environments. Microencapsulation in this study was carried out using the extrusion method with a matrix of sodium alginate concentrations of 2%, 3%, and 4%. The three concentrations of sodium alginate were tested for their ability to protect Lactobacillus casei ATCC 393 from the effects of gastric acid simulation fluid. From the viability test, the results of enumeration of cells in the concentration of sodium alginate 2%, 3% and 4% were 3.08 x 106 colonies / gram; 7.41 x 104 colonies / gram; and 1.01 x 107 colonies / gram. The three MLNs with the three concentrations were incubated in gastric acid simulation fluid (0.08 M HCl; 0.2% NaCl; pH 1.5) for 120 minutes. The enumeration results of MLN viability after testing the gastric acid liquid at a concentration of 4% were 4.5 x 103 colonies / gram, whereas at a concentration of 2% and 3% the viability value was
Pengkajian Administrasi Resep Anak Di Salah Satu Puskesmas Kabupaten Tangerang Yardi Saibi; nelly suryani; Shella Desilia Pratiwi
Farmasains : Jurnal Ilmiah Ilmu Kefarmasian Vol. 8 No. 2 (2021)
Publisher : Universitas Muhammadiyah Prof. DR. HAMKA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/farmasains.v8i2.4909

Abstract

Pengkajian resep anak penting untuk dilakukan untuk mencegah terjadinya medication error. Penelitian ini bertujuan untuk melakukan pengkajian resep pasien anak-anak di salah satu puskesmas yang ada di wilayah kabupaten Tangerang. Penelitian ini merupakan penelitian cross sectional deskriptif. Populasi adalah seluruh resep pasien pediatri pada rawat jalan. Sampel yang diambil sebanyak 100 resep secara acak sederhana . Kriteria inklusi yaitu seluruh resep pasien pediatri rawat jalan pada bulan Desember tahun 2018 di unit ruang pelayanan kefarmasian. Kriteria eksklusi yaitu resep pasien pediatri yang tidak dapat terbaca oleh peneliti. Klirens etik penelitian didapatkan dari Komite Etik Penelitian Kesehatan Fakultas Kedokteran Universitas Indonesia. Data diolah dengan menggunakan analisa statistik univariat. Hasil penelitian menunjukkan bahwa aspek kelengkapan administrasi yang sudah lengkap yakni nama pasien, umur dan tanggal penulisan resep (100%). Tiga aspek lainnya yang sama sekali tidak memenuhi kelengkapan yakni jenis kelamin pasien, berat badan pasien serta ruangan/unit asal resep (0%). Dari persyaratan farmasetik, aspek bentuk sediaan dan kekuatan sediaan sama sekali tidak ditemukan pada resep (0%). Sedangkan dosis, jumlah dan aturan pemakaian obat memenuhi syarat kelengkapan. Dapat disimpulkan bahwa pengkajian resep secara administrasi dan farmasetik di puskesmas ini perlu dilakukan sebagai upaya untuk mengevaluasi kelengkapan resep yang sesuai dengan standar pelayanan yang berlaku.