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Analisis Kebijakan Manajemen Logistik Obat Farmasi Terhadap Persedian Obat Di Rumah Sakit Umum Royal Prima Medan Tahun 2018 Panjaitan, Dian; Ginting, Chrismis Novalinda; Suyono, Tan
SCIENTIA JOURNAL Vol 8 No 2 (2019): SCIENTIA JOURNAL
Publisher : Universitasdiwangsa Jambi

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Pengelolaan obat merupakan salah satu segi manajemen rumah sakit yang sangat penting dan saling terkait yang dimulai pemilihan, perencanaan,  pengadaan,  penerimaan, penyimpanan, pendistribusian, pemusnahan dan penarikan, pengendalian, dan administrasi. Tujuan Peneltian ini untuk Mengetahui Analisa   Di Rumah Sakit Royal Prima Medan Tahun 2018. Penelitian dilakukan pada bulan bulan Januari tahun 2019. Sampel dalam penelitian ini adalah seluruh  pengelola  obat  di  wilayah kerja Rumah Sakit Royal Prima Medan, Dengan jumlah sampel 35 orang. Penelitian menggunakan uji Chi-Square. Ada hubungan perencanaan kebutuhan terhadap persedian obat di Rumah Sakit UmumRoyal Prima Medan Tahun 2018. Ada hubungan perencanaan kebutuhan terhadap persedian obat di Rumah Sakit Umum Royal Prima Medan Tahun 2018. Ada hubungan perencanaan kebutuhan terhadap persedian obat di Rumah Sakit Umum Royal Prima Medan Tahun 2018. Ada hubungan Pendistribusian obat terhadap persedian obat di Rumah Sakit UmumRoyal Prima Medan Tahun 2018. Ada hubungan perencanaan kebutuhan terhadap persedian obat di Rumah Sakit Umum Royal Prima Medan Tahun 2018. Tidak ada hubungan penarikan dan pemusnahan obat terhadap persedian obat di Rumah Sakit Umum Royal Prima Medan Tahun 2018. Bagi pihak rumah sakit diharapkan pihak rumah sakit harus tetap memperhatikan dan meningkatkan Perencanaan kebutuhan, pengadaan, penerimaan, penyimpanan, pendistribusian, pemusnahan dan penarikan dalam persedian obat di Rumah Sakit Umum Royal Prima Medan Tahun 2018 agar terciptanya pelayanan yang bermutu dan berkualitas tinggi di Rumah Sakit Royal Prima Medan.

ANALISIS Manalu, Andika Prianto; Ginting, Chrismis Novalinda; Nasution, Sri Wahyuni
Jurnal Ilmiah Permas: Jurnal Ilmiah STIKES Kendal Vol 10 No 2 (2020): April 2020
Publisher : LPPM STIKES KENDAL

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Infeksi nosokomial sangat berpengaruh terhadap kondisi kesehatan pasien secara menyeluruh dan dapat meningkatkan morbiditas serta mortalitas. Akan tetapi, angka kejadian infeksi nosokomial hingga saat ini masih tinggi. Masalah pada penelitian ini adalah kurangnya kemampuan perawat dalam mencegah dan mengendalikan infeksi nosokomial. Tujuan penelitian ini adalah untuk mengetahui dan menganalisis kemampuan perawat terkait hal tersebut serta determinannya di RSU Royal Prima Medan. Jenis penelitian ini adalah penelitian kualitatif dengan pendekatan interaktif. Sumber informan sebanyak 7 orang perawat pelaksana, 7 orang kepala ruang dan 1 orang Tim PPI. Hasil penelitian menunjukkan bahwa 8 kemampuan perawat dalam pencegahan dan pengendalian infeksi nosokomial belum maksimal sesuai dengan aturan menurut WHO. Determinan dalam pelaksanaannya antara lain pendidikan perawat, lama bekerja, tempat tugas, kebutuhan SDM dan alat pendukung, kenyamanan terhadap fasilitas pendukung, pelatihan/sosialisasi, monitoring dan evaluasi serta koordinasi antar unit. Kesimpulan penelitian bahwa kemampuan perawat dalam pencegahan dan pengendalian infeksi nosokomial di RSU Royal Prima Medan sudah tergplong baik namun terdapat beberapa hambatan dalam pelaksanaannya.

Comparison of Antioxidant and Anti-collagenase Activity of Genistein and Epicatechin Geeta,; Widodo, Wahyu Setia; Widowati, Wahyu; Ginting, Chrismis Novalinda; Lister, I Nyoman Ehrich; Armansyah, Adek; Girsang, Ermi
Pharmaceutical Sciences and Research
Publisher : UI Scholars Hub

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Background: Skin aging is a complex natural process caused by both intrinsic or genetically programmed aging and extrinsic aging caused by environmental factors, such as free radical. The use of antioxidant and anti-collagenase to prevent the aging proses has been known. Natural compounds from plants are one of the sources of antioxidant and anti-collagenase that has ability to prevent aging. Genistein and Epicatechin are the major phenolic compound found in G. max. Objectives: This research was to evaluate the antiaging potential of genistein and epicatechin through antioxidant activity assay (ABTS-reducing activity assay) and collagenase inhibitory activity assay. Methods: Antioxidant analysis of Genistein and Epicatechin was performed by 2,2’- azinobis-3-ethylbenzo-thiazoline-6-sulfonic acid (ABTS) reducing activity Assay. Antiaging assay was conducted through inhibitory of collagenase, one of important enzyme in aging process. Results: ABTS- reducing activity assay showed that both compounds had great ABTS-reducing activity in which epicatechin had better activity than genistein. Epicatechin had low value of IC50 ABTS-reducing activity around 14.39 µg/ml better than genistein with IC50 about 43.17 µg/ml. In terms of collagenase inhibitory activity assay, epicatechin had lower value of IC50 (9.08+-3.46 ug/ml), better than genistein (98.74+-4.25 ug/ml). Conclusion: Epicatechin had higher antioxidant and anti- collagenase activity compared to Genistein.

Antioxidant and Elastase Inhibitor Potential of Petals and Receptacle of Rose Flower (Rosa damascena) Mawarni, Evi; Ginting, Chrismis Novalinda; Chiuman, Linda; Girsang, Ermi; Handayani, Rr. Anisa Siwianti; Widowati, Wahyu
Pharmaceutical Sciences and Research
Publisher : UI Scholars Hub

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Free radicals can cause damage to cells or tissues, autoimmune diseases, degenerative diseases, or cancer. Therefore, the body needs important substances, namely antioxidants that can help protect the body by reducing negative effect from free radicals. Rose flower (Rosa damascena) has anthocyanin pigment which belongs to flavonoid group which has a function as antioxidant or free radical scavenger. This study aims to determine antioxidant and anti-elastase potentials of rose petals and receptacles. The method used in this study was a qualitative phytochemical test to determine the compounds contained in the Rose Petal Extract (RPE) and Rose Receptacle Extract (RRE), ABTS ((2,2’-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid))-reducing assay to determine antioxidant activity, and antiaging test with anti-elastase assay. RPE and RRE contained flavonoids, phenols, tannins and alkaloids, but did not contain saponins. RPE contained triterpenoids and terpenoids, while RRE contained steroids, but did not contain terpenoids. The inhibitory concentration (IC50) values in the ABTS reducing assay were 4.46 ± 0.34 μg/mL (RPE) and 15.49 ± 0.23 μg/mL (RRE), while the results of the anti-elastase assay were 17.51 ± 1.47 μg/mL (RPE) and 58.91 ± 2.31 μg/mL (RRE). Both RPE and RRE are potent antioxidant and anti-elastase, and RPE is more active than RRE in these assays.

Exploring Factors Behind Women Do Not Give Birth at Health Facilities in Nias Barat Zebua, Sawato; Girsang, Ermi; Nasution, Sri Lestari Ramadhani; Ginting, Chrismis Novalinda
Jurnal Aisyah : Jurnal Ilmu Kesehatan Vol 6, No 4: December 2021
Publisher : Universitas Aisyah Pringsewu

Choosing a location for delivery by pregnant women and deliveries assisted by skilled health workers are important keys in reducing MMR and IMR. The low birth rate at health facilities in Mandrehe Utara Subdistrict, Nias Barat Regency is a serious challenge to achieve the success of the maternal and child health service program. This study analyzes the factors that influence pregnant women who do not give birth in health facilities. This study uses a quantitative method with a cross-sectional approach. The samples were 180 people. The data were collected using a questionnaire and then tested using the Chi-Square test and logistic regression test. The results showed that the reason why mothers did not choose to give birth in health facilities was influenced by knowledge (p=0.022), attitude toward birth attendants (p=0.002), perception of distance (p=0.004), husband and family support (p=0.000), and access to health information (p=0.007). The role of health workers had no significant effect in this study (p=0.756). The results of the logistic regression test showed that husband and family support was the most dominant variable affecting mothers who did not give birth in health facilities. Mothers who perceive the lack of support from their husbands and families are 5,668 times more to choose to give birth outside a health facility. Education and socialization by health workers to mothers and their husbands and families are suggested to increase knowledge, awareness and change attitudes. No less important are the government's efforts to provide health facilities and infrastructure development to reduce access difficulties.Pemilihan lokasi persalinan oleh ibu hamil dan persalinan yang ditolong tenaga kesehatan terampil menjadi kunci penting dalam menurunkan AKI dan AKB. Rendahnya angka persalinan di fasiltas kesehatan di Kecamatan Mandrehe Utara Kabupaten Nias Barat menjadi tantangan berat untuk mencapai keberhasilan program pelayanan kesehatan ibu dan anak. Studi ini bertujuan menganalisis faktor-faktor yang mempengaruhi ibu hamil tidak bersalin di fasilitas kesehatan. Studi ini menggunakan metode kuantitatif dengan pendekatan cross-sectional. Sampel yang terlibat sebanyak 180 orang. Pengumpulan data menggunakan kuesioner dan kemudian diuji dengan menggunakan uji Chi-Square dan uji regresi logistik. Hasil penelitian menujukkan penyebab ibu tidak memilih bersalin di fasilitas kesehatan dipengaruhi oleh pengetahuan (p=0,022), sikap terhadap penolong persalinan (p=0,002), persepsi tentang jarak (p=0,004), dukungan suami dan keluarga (p=0,000), dan akses terhadap informasi kesehatan (p=0,007). Peran petugas kesehatan tidak berpengaruh signifikan dalam studi ini (p=0,756). Hasil uji regresi logistik menunjukkan dukungan suami dan keluarga merupakan variabel yang paling dominan mempengaruhi ibu tidak melahirkan di fasilitas kesehatan. Ibu yang menganggap kurangnya dukungan suami dan keluarga berpeluang 5,668 kali memilih melahirkan di luar fasilitas kesehatan. Edukasi dan sosialisasi oleh tenaga kesehatan terhadap ibu beserta suami dan keluarga disarankan untuk peningkatan pengetahuan, kesadaran dan perubahan sikap. Tidak kalah penting upaya dari pemerintah untuk penyediaan fasilitas kesehatan dan pembangunan infrastruktur guna memangkas kesulitas akses.

Potential Protective Effects of Balakka Fruit Extract (Phyllanthus emblica L.) Against Doxorubicin-Induced Pancreatic Toxicity in Rats Harahap, Viora Rezky; Ikhtiari, Refi; Ginting, Chrismis Novalinda; Raif, Martinus Ahmad
Jurnal Aisyah : Jurnal Ilmu Kesehatan Vol 5, No 1: June 2020
Publisher : Universitas Aisyah Pringsewu

The incidence of cancer is still high in the world, regionally and in Indonesia, where the incidence of new cases of breast cancer, uterine cervical cancer and lung cancer is the highest in Indonesia. The use of anthracycline doxorubicin as an anti-neoplastic agent is highly effective in various types of cancer in adults and children, including hematologic and solid tumors, but doxorubicin has serious organotoxicity, including pancreatic toxicity. The content of various compounds from Balakka fruit extract (Phyllanthus emblica L.) which has been identified through various studies, especially its potential as a pancreatic protective agent, through its antioxidant, anti-diabetic/hyperglycemic, and anti-hyperlipidemic activities. To determine the potential protective effect of ethanolic extract of Balakka fruit (Phyllanthus emblica L.) against doxorubicin-induced pancreatic toxicity in rats. This study used an experimental study with a completely randomized design to determine the potential protective effect of the ethanolic extract of Balakka fruit (Phyllanthus Emblica L.) against doxorubicin-induced pancreatic toxicity in rats (Rattus norvegicus). The results of qualitative phytochemical tests on the ethanolic extract of Balakka fruit contain alkaloids, flavonoids, phenols, steroids/triterpenoids, terpenoids and tannins. From the results of the different test results in the mean serial blood glucose levels more than 2 Kruskal Wallis groups, a significance value of p less than 0.05 was found, meaning that there were at least 2 groups that had a significant difference in fasting glucose levels (p = 0.003*) and TTGO test results at the 30th minute, 60th minute and 120th minute (p = 0.000*; p = 0.001*; p = 0.007*). The average fasting blood glucose levels of all treatment groups were in the normal range of 90 – 110 mg/dL. At the 120th minute of OGTT, it was found that the mean blood glucose level in the doxorubicin group reached 149.00 ± 7.99 mg/dL, still higher than the average level of the extract group, treatments 1 and 2 (p less than 0.05). And the mean blood glucose levels in the treatment groups 1 and 2 were significantly lower than the mean blood glucose levels in the doxorubicin group (p = 0.009*; p = 0.009*).The ethanolic extract of Balakka Phyllanthus Emblica L. fruit contains flavonoids, phenols, tannins, triterpenoids, terpenoids and alkaloids. Administration of ethanolic extract of Balakka fruit at a dose of 400 mg/kgBW can overcome pancreatic toxicity by maintaining a balance of glucose levels by decreasing blood glucose levels at the 30th minute, 60th minute, and 120th minute close to normal and can improve the pancreatic tissue of rats in a group of mice with doxorubicin-induced hepatotoxicity.

Potential Ethyl Acetate Fraction of Mangkokan Leaf Extract (Nothopanax Scutellarium) in Hyperglycemic Rats: A Systematic Review Nasution, Sri Lestari Ramadhani; Ginting, Chrismis Novalinda; Lister, I Nyoman Ehrich
Jurnal Aisyah : Jurnal Ilmu Kesehatan Vol 7, No 1: March, 2022
Publisher : Universitas Aisyah Pringsewu

Mangkokan leaves (Nothopanax scutellarium) contain various phytochemicals such as flavonoids and saponins, where these compounds have antioxidant activity that can improve oxidative stress in the body. Treatment of Diabetes Mellitus disease can be done with drugs and herbs, optimal blood glucose control alone cannot prevent complications. The available therapies for DM include insulin therapy and other hypoglycemic agents that can not be separated from various side effects and failure to significantly prevent complications, including the Mangkokan leaf herbal treatment (Nothopanax scutellarin) which has an antidiabetic effect. To systematically review the effect of the ethyl acetate fraction of the extract of the Mangkokan (Nothopanax scutellarium) leaf extract on blood sugar levels, malondialdehyde, insulin expression in pancreatic cells and pancreatic histopathology in hyperglycemic rats. A systematic search was carried out in the PubMed database, Medline, Web of Science, Scopus, EMBASE from 2017 to 2021. The reported results stated that Alloxan is a compound that has diabetogenic properties and is toxic especially to pancreatic beta cells and when administered to animals will cause the rat to be diabetic. Alloxan causes damage to pancreatic beta cells by activating reactive oxygen (ROS) which is initiated by the reduction reaction of alloxan.Daun mangkokan (Nothopanax scutellarium) mengandung berbagai fitokimia seperti flavonoid dan saponin, dimana senyawa tersebut memiliki aktivitas antioksidan yang dapat meningkatkan stres oksidatif dalam tubuh. Pengobatan penyakit Diabetes Mellitus dapat dilakukan dengan obat-obatan dan herbal, pengendalian glukosa darah yang optimal saja tidak dapat mencegah terjadinya komplikasi. Terapi yang tersedia untuk DM antara lain terapi insulin dan agen hipoglikemik lainnya yang tidak lepas dari berbagai efek samping dan kegagalan untuk mencegah komplikasi secara nyata, termasuk pengobatan herbal daun mangkokan (Nothopanax scutellarin) yang memiliki efek antidiabetik. Mengkaji secara sistematis pengaruh fraksi etil asetat ekstrak ekstrak daun mangkokan (Nothopanax scutellarium) terhadap kadar gula darah, malondialdehid, ekspresi insulin pada sel pankreas dan histopatologi pankreas pada tikus hiperglikemik. Penelusuran sistematis dilakukan di database PubMed, Medline, Web of Science, Scopus, EMBASE dari tahun 2017 hingga 2021. Hasil yang dilaporkan menyatakan bahwa Alloxan merupakan senyawa yang memiliki sifat diabetogenik dan bersifat toksik terutama terhadap sel beta pankreas dan bila diberikan pada hewan akan menyebabkan tikus menjadi diabetes. Aloksan menyebabkan kerusakan sel beta pankreas dengan mengaktifkan oksigen reaktif (ROS) yang diawali dengan reaksi reduksi aloksan.

Utilization of Online Learning Modules to Increase Nurse Capacity in the Implementation of Nursing Care Documentation Irawan, Feri; Ginting, Chrismis Novalinda; Nasution, Sri Wahyuni
Jurnal Aisyah : Jurnal Ilmu Kesehatan Vol 7, No 1: March, 2022
Publisher : Universitas Aisyah Pringsewu

Nursing care documentation is still a problem in many developing countries due to individual and organizational factors. Providing education is believed to be able to improve the competence and compliance of nurses in documenting nursing care. This study analyzes the use of online learning modules to increase the capacity of nurses in the implementation of nursing care documentation at Rantau Prapat city administration public hospital. The type of research used is a quasi-experimental approach with a pre-post test design approach with a control group. The population in this study were all nurses in the inpatient ward of Rantau Prapatcity administration public hospital, totalling 160 people and a sample of 31 nurses for the intervention group and 31 nurses for the control group. Collecting data with primary and secondary data and the data were analyzed using the Mann–Whitney test. The results showed that there were differences in the knowledge, attitudes and actions of nurses regarding the documentation of nursing care before and after the online module learning was performed. The increase in scores on these three aspects was higher in the intervention group than in the control group. Clinical supervision by the head of the room is also recommended to be performed regularly and continuously so that nurses can be motivated in improving documentation that is oriented toward quality nursing care services. Abstrak: Pendokumentasian asuhan keperawatan masih menjadi permasalahan di berbagai negara berkembang dikarenakan faktor individual maupun faktor organisasional. Pemberian edukasi dipercaya mampu meningkatkan kompetensi dan kepatuhan perawat dalam melakukan pendokumentasian asuhan keperawatan. Penelitian ini bertujuan untuk menganalisis penggunaan modul pembelajaran online untuk meningkatkan kapasitas perawat dalam pelaksanaan pendokumentasian asuhan keperawatan di RSUD Rantau Prapat. Jenis penelitian yang digunakan adalah quasi experiment dengan pendekatan pre-post test design with control group. Populasi dalam penelitian ini adalah seluruh perawat pelaksana di ruang rawat inap RSUD Rantau Prapat yang berjumlah 160 orang dan sampel sebanyak 31 perawat untuk kelompok intervensi dan 31 perawat untuk kelompok kontrol. Pengumpulan data dengan data primer dan sekunder dan data dianalisis dengan uji Mann-Whitney. Hasil penelitian menunjukkan bahwa terdapat perbedaan pengetahuan, sikap dan tindakan perawat tentang pendokumentasian asuhan keperawatan sebelum dan sesudah dilakukan pembelajaran modul online. Peningkatan skor pada ketiga aspek tersebut lebih tinggi pada kelompok intervensi dibandingkan pada kelompok kontrol. Supervisi klinis oleh kepala ruangan juga dianjurkan untuk dilakukan secara teratur serta berkelanjutan agar perawat dapat termotivasi dalam meningkatkan pendokumentasian yang berorientasi pada pelayanan asuhan keperawatan yang berkualitas.

Cognitive Behavioral Therapy for Diabetic Patients Mendrofa, Trisman Basri; Girsang, Ermi; Nasution, Sri Lestari Ramadhani; Ginting, Chrismis Novalinda
Jurnal Aisyah : Jurnal Ilmu Kesehatan Vol 7, No 1: March, 2022
Publisher : Universitas Aisyah Pringsewu

Improving self-care in T2DM patients is critical so that patients can achieve targeted blood glucose levels to prevent complications and independently perform daily tasks to improve their quality of life and life satisfaction. Psychological intervention is believed to be able to change a person's behavior towards a better direction in disease control and prevention. This study measures the impact of Cognitive-Behavioural Therapy (CBT) interventions on the self-care management of T2DM patients. This quasi-experimental study used a pretest-posttest with a control group design. The research subjects were divided into two groups, namely the intervention group (35 people) and the control group (35 people). The study was conducted at the Tello Primary Health Center in April 2021. The data were analyzed using the t-dependent test (?=0.05). The results of the study showed that in the intervention group, there were differences in the self-care management of T2DM patients before and after being given CBT, which included eating patterns (p less than 0.001; 95%CI -6.663-(-4.796)), physical activity (p less than 0.001; 95% CI -5.344-(-4.370)), and attitude (p= less than 0.001; 95%CI -13.086-(-10.114)). In the control group, there was no difference in the self-care management of T2DM patients, which included eating patterns (p= 0.083; 95%CI -0.183-0.012), physical activity (p= 0.058; 95%CI -0.291-0.005), and T2DM patients attitudes (p= 0.094; 95%CI -0.225-0.003). This means that CBT effectively improves the self-care management of T2DM patients.Abstrak: Peningkatan perawatan diri pada pasien DM tipe 2 sangat penting dilakukan agar pasien dapat mencapai kadar glukosa darah yang ditargetkan untuk mencegah komplikasi dan secara mandiri melakukan tugas sehari-hari sehingga meningkatkan kualitas hidup dan kepuasan hidup mereka. Intervensi psikologis dipercaya mampu mengubah perilaku seseorang ke arah yang lebih baik dalam pengendalian dan pencegahan penyakit. Studi ini bertujuan mengukur dampak intervensi Cognitive–behavioural therapy (CBT) terhadap manajemen perawatan diri pasien DM tipe 2. Quasi-experimental study ini menggunakan desain pretest-posttest with control group design. Subjek penelitian dibagi ke dalam dua kelompok yaitu kelompok intervensi (35 orang) dan kelompok kontrol (35 orang). Penelitian dilakukan di Puskesmas Tello pada bulan April tahun 2021. Data dianalisis menggunakan uji t-dependent (p=0,05). Hasil studi menunjukkan bahwa pada kelompok intervensi terdapat perbedaan manajemen perawatan diri pasien DM tipe 2 sebelum dan sesudah diberikan CBT yang meliputi pola makan (p kurang dari 0,001; 95%CI -6,663-(-4,796)), aktivitas fisik (p kurang dari 0,001;95%CI -5,344-(-4,370)), dan sikap (p kurang dari 0,001; 95%CI -13,086-(-10,114)). Sedangkan pada kelompok kontrol, tidak terdapat perbedaan manajemen perawatan diri pasien DM tipe 2 yang meliputi pola makan (p= 0,083; 95%CI -0,183-0,012), aktivitas fisik (p= 0,058;95%CI -0,291-0,005), dan sikap pasien DM (p= 0,094; 95%CI -0,225-0,003). Artinya CBT efektif dalam meningkatkan manajemen perawatan diri pasien DM tipe 2.

Prevalence and Determinants of Drug Adherence in Type 2 Diabetes Mellitus Patients Mendrofa, Tuho Konsultasi; Girsang, Ermi; Nasution, Sri Lestari Ramadhani; Ginting, Chrismis Novalinda
Jurnal Aisyah : Jurnal Ilmu Kesehatan Vol 7, No 1: March, 2022
Publisher : Universitas Aisyah Pringsewu

Compliance with type 2 patients with DM in taking medication is an important key in maintaining blood glycemic levels and preventing complications. This study was conducted to determine the prevalence and to investigate the determinants of medication adherence in type 2 patients with DM. A total of 250 types 2 patients with DM who visited Pulau Tello Health Center, South Nias Regency, were involved in this cross-sectional study. Collecting data using questionnaires and patient medical records. The results showed that the motivational variables (p= less than 0.001; PR= 2; 95%CI 1.560-2.668), family support (p= less than 0.001; PR = 4.2; 95%CI 2.827-6.496), individual coping (p = less than 0.001; PR=1.9; 95%CI 1.409-2.267), and income (p= less than 0.001; PR=1.7; 95%CI 1.346-2.258) were associated with medication adherence in type 2 patients with DM. family is the dominant variable that influences medication adherence in type 2 patients with DM. Patients with DM who does not adhere to medication are 7.8 times more likely to have poor support than patients who adhere to medication.Abstrak: Kepatuhan pasien DM tipe 2 dalam mengonsumsi obat menjadi kunci penting dalam menjaga glikemik darah dan pencegahan komplikasi. Studi ini dilakukan untuk mengetahui prevalensi dan menyelidiki determinan kepatuhan minum obat pada pasien DM tipe 2. Sebanyak 250 orang pasien DM tipe 2 yang berkunjung di Puskesmas Pulau Tello, Kabupaten Nias Selatan dilibatkan dalam studi cross-sectional ini. Pengumpulan data menggunakan kuesioner dan rekam medis pasien. Hasil penelitian menunjukkan bahwa variable motivasi (p= kurang dari 0,001; PR= 2; 95%CI 1,560-2,668), dukungan keluarga (p= kurang dari 0,001;PR = 4,2; 95%CI 2,827-6,496), koping individu (p= kurang dari 0,001; PR=1,9; 95%CI 1,409-2,267), dan pendapatan (p= kurang dari 0,001; PR= 1,7; 95%CI 1,346-2,258) berhubungan dengan kepatuhan minum obat pasien DM tipe 2. Dukungan keluarga merupakan variabel yang dominan berpengaruh terhadap kepatuhan minum obat pada pasien DM tipe 2. Pasien DM yang tidak patuh minum obat 7,8 kali kecenderungannya memiliki dukungan yang kurang baik dibanding dengan pasien yang patuh minum obat.

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