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All Journal Jurnal Farmasi Udayana Jurnal Sains dan Teknologi Pharmaciana: Jurnal Kefarmasian Farmasains : Jurnal Ilmiah Ilmu Kefarmasian JPSCR : Journal of Pharmaceutical Science and Clinical Research Jurnal Riset Kesehatan Nasional Jurnal Ilmiah Medicamento Jurnal Penelitian Agama Hindu Jurnal Kesehatan Primer JRKN
Dwi Arymbhi Sanjaya
Universitas Mahasaraswati Denpasar
Religion Humanities Computer Science & IT Education Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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Journal : Jurnal Sains dan Teknologi

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Antidepressant-Like Activity and Physicochemical Analysis of Essential Oils from Michelia alba and Plumeria alba Flowers Ni Made Dwi Mara Widyani Nayaka; Ni Luh Putu Swari; Dewa Ayu Sri Bintang Widnyani; Ni Kadek Sukmayanti; Putu Era Sandhi Kusuma Yuda; I Gusti Ayu Agung Kusuma Wardani; Dwi Arymbhi Sanjaya
JST (Jurnal Sains dan Teknologi) Vol. 11 No. 2 (2022)
Publisher : Universitas Pendidikan Ganesha

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (270.576 KB) | DOI: 10.23887/jstundiksha.v11i2.45291

Abstract

Depression is a mental disorder with an increased prevalence. Other than conventional antidepressants, essential oils have been used in aromatherapy as a complementary and alternative medicine to reduce depression. In the current study, the antidepressant-like activity of the inhalation of essential oils from Michelia alba (MAEO) and Plumeria alba (PAEO) flowers was analyzed using the forced swim test. The immobility time of mice from tested groups was evaluated statistically by the non-parametric Kruskal Wallis test, followed by the Mann Whitney post hoc test. Also, the characterization of both essential oils was determined by refractive index, solubility, and Gas Chromatography-Mass Spectrophotometry (GC-MS) analysis. PAEO showed stronger antidepressant-like activity than MAEO (p<0.05) and it was equal to the positive control (essential oil of Lavandula angustifolia) (p>0.05). The GC-MS analysis revealed some calming agents in MAEO and PAEO such as linalool, linalyl acetate, phenylethyl alcohol, and methyl anthranilate.
Co-Authors AA Istri Mas Padmiswari Agus Baratha Suyasa Asthadi Mahendra Bhandesa, Asthadi Mahendra Dewa Ayu Sri Bintang Widnyani Emanuel Ileatan Lewar Erna Cahyaningsih Fitria Megawati Herleeyana Meriyani I Gede Agus Shuarsedana Putra I Putu Yudistira Mahaputra Ida Ayu Manik Damayanti Luh Risma Putri Rahayu Made Agus Deny Mahendra Putra Made Gek Adisti Kamalia Ni Kadek Sukertiasih Ni Kadek Sukmayanti Ni Luh Kade Arman Anita Dewi Ni Luh Putu Inca Buntari Agustini Ni Luh Putu Swari Ni Made Dwi Mara Widyani Nayaka Ni Made Wiwik Setiawati Ni Wayan Sukma Antari Nyoman Budiartha Siada Putu Era Sandhi Kusuma Yuda Putu Sukma Purnamasari RR. Asih Juanita Triska Ananda Rahayu Wardani, I Gusti Agung Ayu Kusuma