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Journal : Proceedings of the International Conference on Nursing and Health Sciences

Development of the Obesity Nutraceutical from Raja and Kepok Banana Peels Kezia Elian Devina; Dono Indarto; Tri Nugraha Susilawati
Proceedings of the International Conference on Nursing and Health Sciences Vol 4 No 1 (2023): January-June 2023
Publisher : Global Health Science Group

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/picnhs.v4i1.1817

Abstract

Patients with obesity often fail to control their body weight through diet and physical activity, while the existing anti-obesity drugs have some side effects for long-term use. Banana is Indonesia's tropical fruits with the highest production, and the banana peel has become soil waste. This study aimed to analyze nutrients and active compounds of methanol extracts of raja and kepok banana peels (ERP and EKP respectively). Macro and micro-nutrient compositions of the ERP and EKP were determined using the proximate analysis, while Thin Layer Chromatography (TLC) was used to detect the ERP and EKP active compounds. The ERP contained 0.11% crude fibers, 4.44% fat, and 58.08% carbohydrates, different from the EKP (4.25% protein, 20.95% water, and 14.45% minerals). By contrast, both the ERP and EKP contained flavonoids, phenols, tannins, alkaloids, and saponins. In conclusion, ERP is potentially developed as a nutraceutical for obesity treatment in the future. Further study is needed to measure specific fat levels and to analyze specific active compounds in the ERP which can modulate gene expression and interact with protein targets in lipid metabolism.
Nutritional Analysis of Sweet Orange Peel Extract for Development of Obesity Treatment Winda Rizki Pebrina Batubara; Tri Nugraha Susilawati; Dono Indarto
Proceedings of the International Conference on Nursing and Health Sciences Vol 4 No 1 (2023): January-June 2023
Publisher : Global Health Science Group

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/picnhs.v4i1.1820

Abstract

Obesity is a complex chronic disease that becomes the main factor of cardiometabolic diseases such as heart diseases, stroke and diabetes mellitus. Oxidative stress is involved in the obesity pathogenesis. Diet and physical exercise are recommended for obesity treatment but many obese people have low compliance to these treatments. Sweet orange (Citrus sinensis L.) is an Indonesian fruit with high production per year. This fruit pulp contains high vitamin C level, which is widely used as a strong anti oxidant to inhibit oxidative stress. However, sweet orange peel is just thrown in the soil and becomes rubbish. Therefore, the aim of this study was to analyze nutritional contents of sweet orange peel extract (OPE). Fresh orange peels were obtained from a local market at the Surakarta city and the dried orange peels were extracted using ethanol solvent. Carbohydrate, protein, and fat levels were determined using the existing method at the Food Technology Laboratory while vitamin C and Magnesium (Mg) levels were determined using the spectrophotometric and SSA-flame methods respectively. 100g OPE contained 68.88% carbohydrate, 3.23% protein, 3.41% fat, 1556.6 mg vitamin C and 239.74 mg Mg. In conclusion, the OPE is a good source of vitamin C and Mg, which can be developed as a nutraceutical for obesity treatment. Further investigation is required to determine active compounds in the OPE, which enhances the beneficial effects of vitamin C and Mg.