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All Journal Acta Pharmaceutica Indonesia Jurnal Profesi Medika: Jurnal Kedokteran dan Kesehatan Syntax Literate : Jurnal Ilmiah Indonesia JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Majalah Farmasi dan Farmakologi (Trends in Pharmacy and Pharmaceutical Sciences) NUSANTARA : Jurnal Ilmu Pengetahuan Sosial JURNAL ILMU KEFARMASIAN INDONESIA Healthy Tadulako Journal (Jurnal Kesehatan Tadulako)
Hesty Utami Ramadaniati
Magister Ilmu Kefarmasian Jurusan Farmasi Rumah Sakit Uniersitas Pancasila
Humanities Dentistry Economics, Econometrics & Finance Education Environmental Science Health Professions Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health

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EVALUASI PENGGUNAAN ANTIBIOTIKA PADA PASIEN PNEUMONIA KOMUNITAS DI INSTALASI RAWAT INAP RSPAD GATOT SUBROTO Iyan Hardiana; Dian Ratih Laksmitawati; Hesty Utami Ramadaniati; Sutarno
Majalah Farmasi dan Farmakologi Vol. 25 No. 1 (2021): MFF
Publisher : Faculty of Pharmacy, Hasanuddin University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20956/mff.v25i1.11555

Abstract

Resistensi antibiotik merupakan masalah yang serius karena dapat menyebabkan tidak tercapainya tujuanterapi, meningkatnya efek samping obat, dan pemborosan dari segi ekonomi. Penelitian ini bertujuan untukmengevaluasi penggunaan antibiotika pasien pneumonia komunitas di instalasi rawat inap RSPAD GatotSubroto. Penelitian ini bersifat cross sectional dengan pengambilan data secara prospektif di instalasi rawatinap periode September – November 2019. Penggunaan antibiotika dievaluasi menggunakan metode Gyssensselanjutnya dilakukan analisis korelasi antar kerasionalan dengan outcome terapi menggunakan uji Spearman.Hasil penelitian menunjukkan karakteristik pasien pneumonia komunitas berdasarkan kategori umur yangpaling banyak yaitu > 66 tahun dengan jumlah 23 pasien (53.49%), kategori jenis kelamin yang palingmendominasi laki – laki sebanyak 24 pasien (55.81%) dari jumlah total 43 pasien yang memenuhi kriteriainklusi. Berdasarkan hasil evaluasi penggunaan antibiotik dengan metode Gyssens diperoleh 28 pasienmenggunakan antibiotik dengan tepat (kategori 0) dan 15 pasien menggunakan antibiotik tidak tepat (kategoriI – VI). Antibiotika yang termasuk kategori IVA sebanyak 6 kasus (6.82%), kategori IVC sebanyak 2 kasus(2.27%), kategori IIIA sebanyak 5 kasus (5.68%), dan kategori IIIB sebanyak 9 kasus (10.23%). Analisis statistikmenunjukkan bahwa terdapat hubungan yang kuat antara penggunaan antibiotika yang rasional dalammempengaruhi outcome terapi (r=0.533)
STRUKTUR BIAYA SENDIRI DAN FAKTOR PENENTU KESULITAN EKONOMI PADA PASIEN GAGAL GINJAL KRONIS DENGAN TERAPI HEMODIALISIS DI RUMAH SAKIT SENTRA MEDIKA CIBINONG Koswara Rahajeng, Suny; Sarnianto, Prih; Utami Ramadaniati, Hesty
Healthy Tadulako Journal (Jurnal Kesehatan Tadulako) Vol. 6 No. 2 (2020)
Publisher : Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (501.622 KB) | DOI: 10.22487/htj.v6i2.89

Abstract

Gagal ginjal kronis (GGK) mengharuskan terapi hemodialisis (HD) 2–3 kali per minggu.Walau biaya medis langsung telah ditanggung BPJS-K, pasien JKN harus mengeluarkan biaya sendiri dan pendapatan yang hilang saat menjalani HD. Penelitian ini dimaksudkan untuk mengetahui struktur biaya sendiri dan faktor penentu kesulitan ekonomi pasien GGK. Data primer diambil secara potong-lintang melalui wawancara menggunakan kuesioner terstruktur terhadap 101 pasien GGK berusia >18 tahun yang telah menjalani HD selama >1 tahun, di RS Sentra Medika Cibinong, pada Desember 2017 sampai Januari 2018. Hasil penelitian menunjukkan biaya sendiri yang ditanggung [keluarga] pasien meliputi biaya transportasi termasuk parkir (rata-rata Rp316.673/bulan) dan konsumsi (Rp168.400/bulan). Sebagian pasien mengeluarkan biaya untuk membeli obat dan suplemen yang tidak dijamin BPJS-K (rata-rata Rp611.000/bulan) dan biaya untuk pendamping (Rp1.066.667/bulan). Terkait biaya intangible, rerata pendapatan [keluarga] pasien yang hilang mencapai Rp905.365/bulan. Hasil analisis multivariat dengan regresi logistik menunjukkan tanggungan keluarga merupakan faktor penentu terjadinya kesulitan ekonomi (p<0,05; OR = 2,74). Pasien dengan tanggungan keluarga, yaitu anak usia <15 tahun dan/atau orang tua usia >65 tahun, memiliki risiko 2,74 kali lebih besar mengalami kesulitan ekonomi dibanding pasien tanpa tanggungan keluarga
Analysis of Health-related Quality of Life Determinants in Adult Ashmatic Patients in a District Hospital in East Jakarta Hesty Utami Ramadaniati; Sesilia Andriani Keban; Christine Meidiawati
Acta Pharmaceutica Indonesia Vol. 43 No. 1 (2018)
Publisher : School of Pharmacy Institut Teknologi Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Background: Uncontrolled asthma leads to patients' poor outcomes and decreases health-related quality of life/HRQoL. Little research has been done to analyze the determinants of  HRQoL in asthmatics patients. Objective: To determine asthma control and  patients' compliance levels, and evaluate the appropriateness of medicine use and determinants of HRQoL. Methods: During this prospective study, adult asthmatic patients who currently experienced asthma attack were evaluated in asthma clinic of a district hospital in Jakarta and administered study questionnaires. Demographic variables and data related to asthma control, patients' compliance level and the appropriate use of medications were summarized using descriptive statistics. The determinants of HRQoL were determined using bivariate and multivariate regression analysis. All data were analyzed using SPSS version 22.0. Results: There were 11 males and 43 females aged approximately 45 years old. More than 50% of the patients had uncontrolled asthma and low level compliance to their medications. Nearly all medicines used were inappropriate according to National Asthma Treatment Guideline. Bivariate correlation test revealed four factors which significantly determined the total score of HRQoL, namely asthma duration (P=0.033), asthma control level (p=0.007), asthma severity level (p=0.001) and the presence of smoke exposure in neighbourhood (p=0.032). Further, multivariate analysis showed only the presence of smoke exposure  significantly affecting patients' quality of life. Conclusion: This study uncovered the majority of patients had uncontrolled asthma status and low level of compliance to their medications. In addition, this study highlighted the exposure of smoke exposure as the solely determinant of HRQoL amongst  asthmatic patients.
Pengaruh Faktor Determinan terhadap Hasil Terapi Hipertensi Pasien pada Tiga Puskesmas di Jakarta Pusat Andam Dewi Pertiwi; Prih Sarnianto; Hesty Utami Ramadaniati
Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan Vol 13, No 2 (2019): Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan
Publisher : Fakultas Kedokteran UPN Veteran Jakarta Kerja Sama KNPT

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (172.337 KB) | DOI: 10.33533/jpm.v13i2.902

Abstract

Hypertension has been known as risk factor of cardiovascular diseases necessitating the good control of blood pressure. The evident also shows the increased number of uncontrolled hypertensive patients. This study aimed to identify the determinants of controlled blood pressure in primary health centre hypertensive patients. The benefits of this research is to educated to public about factors that influence hypertension controlled. This research lasted for five months was conducted through patient interview of respondents meeting inclusion criteria in three primary health centres/PHC (PHC Menteng, PHC Tanah Abang, and PHC Johar Baru). Some data of the interview were validated by reviewing patient’s medical record. There were 26 factors used to analyse the determinants which included sociodemographic, biophysiology, dietary consumption patterns, use of hormonal contraceptives, physical activity, and stress). The result of multivariate regression analysis revealed two significant determinants, namely the presence of cardiovascular diseases (odd ratio/OR = 0,091, P-value = 0,004) and physical activity (OR = 10,647, P-value = 0,002). Patients with history of cardiovascular disease had 10,99 times risk to experience uncontrolled hypertension compared with those with no history of the disease. In addition, patients with routine physical activity at least 5 days/week (150 minutes/week) were 10,647 times to have controlled blood pressured as opposed to their counterpants.
ANALISIS PROFIL PENGOBATAN, BIAYA PERSPEKTIF RUMAH SAKIT DAN HROQoL PADA PASIEN HEMODIALISIS RAWAT JALAN DI RSUP FATMAWATI JAKARTA Neni Rahmani; Prih Sarnianto; Hesty Utami Ramadaniati
NUSANTARA : Jurnal Ilmu Pengetahuan Sosial Vol 9, No 2 (2022): NUSANTARA : Jurnal Ilmu Pengetahuan Sosial
Publisher : Universitas Muhammadiyah Tapanuli Selatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31604/jips.v9i1.2022.38-46

Abstract

Latar belakang  :Hemodialisis adalah suatu cara untuk memperbaiki kelainan fungsi ginjal,  dilakukan dengan menggunakan mesin hemodialisis. Terapi hemodialisis membutuhkan waktu yang lama dan biaya mahal yang dapat mempengaruhi kualitas hidup.Tujuan Penelitian Mengetahui manajemen profil pengobatan Eritropetin, biaya perspektif rumah sakit, dan faktor-faktor yang mempengaruhi kualitas hidup pasien hemodialisis rawat jalan di RSUP Fatmawati.Metode Penelitian : Metode yang digunakan adalah analisis Cross-Sectional  dengan rentang penelitian 2 bulan, pada pasien dewasa yang minimal 12-36 bulan menjalani hemodialisis Pengumpulan data dilakukan dengan retrospektif dari dokumen, untuk menilai kesesuaian manajemen profil pengobatan Eritropoetin dan secara prospektif dari pengisian kuesioner EQ-5D-5L dan VAS (Visual Analogue Scale) kemudian dilakukan analisis data secara deskriptif dan menggunakan analisis Regresi linier berganda untuk mendapatkan korelasi antara karakteristik terhadap kualitas hidup (VAS dan Utility).Hasil Penelitian : Selama periode 2 bulan jumlah pasien sebanyak 100 orang. Jumlah laki-laki lebih banyak (57 pasien), usia 50-59 tahun sebanyak 30%, 55% bekerja sebagai karyawan, 50% pendidikan SMA, 54% pendapatan kurang Rp 2.000.000,-. Hasil kesesuaian terapi Eritropoetin sudah 100% sesuai menurut pernefri. Biaya riil untuk tindakan hemodialisis sebesar Rp910.570,- lebih kecil dibanding biaya INA-CBGs Rp 982.400,- . Analisis regresi linier VAS menunjukan 3 variabel yang signifikan : depresi (p= 0,003), jenis kelamin (p=0,028), lama hemodialisis (p=0,035). Analisis regresi linier utility ada 1 variabel yang signifikan yaitu pendapatan tiap bulan (p = 0,023).Kesimpulan  : kesesuaian terapi untuk menejemen anemia di sesuai dengan standar terapi menurut pernefri. Biaya persepektif rumah sakit lebih kecil daripada biaya INA-CBGs. Ada tiga variabel yang mempengaruhi kualitas hidup VAS yaitu depresi, jenis kelamin dan lama hemodialisis sedangkan kualitas hidup dari aspek utility hanyak dipengaruhi faktor pendapatan per bulan.  
Parental Use of Internet to Navigate Online Health Information for Their Children: An Indonesian Context Hesty Utami Ramadaniati; Nurita Andayani; Zata Yumni Azizah
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 11, No 4
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.64781

Abstract

Internet-resourced health information becomes increasingly common amongst parents before doctor consultation. This study aimed to explore the demographics of online health information-seeking parents and the type of information on children’s healthcare needs and the relationship between the demographics and the online sources. A cross-sectional study was conducted at two Primary Health Centers (PHC) in Jakarta. The respondents were parents of acutely ill children seeking online health information before visiting PHC. A validated questionnaire was distributed to the respondents. Parents’ demographics and type of information were analyzed descriptively. The relationship between the demographics and the information source was tested using the Chi-Square test. 478 respondents were participating in this study where most of the respondents were mothers (75.1%), aged 26-35 years (57.7%), and had 1-2 children (70.7%). Most of them were high-school graduates (64.9%) and unemployed (49.6%). Google (61.5%) was predominantly the most frequently used digital media, followed by websites run by doctors (21.9%). The most sought information included illness causes, transmission probability, treatment, and medicines’ side effects. There was no significant relationship between any demographics and the types of online sources. In conclusion, illness-related basic information is used by most parents to be informed before seeing doctors. The link between parents’ characteristics and the selection of digital media could not be determined.
Analisis Efektivitas Biaya Seftriakson sebagai Antibiotik Profilaksis Pada Seksio Sesarea: Dosis Tunggal Versus Dosis Berulang Bayu Pertiwi; Hesty Utami Ramadaniati; Prih Sarnianto; Dwirani Amelia
JURNAL ILMU KEFARMASIAN INDONESIA Vol 20 No 2 (2022): JIFI
Publisher : Fakultas Farmasi Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35814/jifi.v20i2.1084

Abstract

The provision of single-dose prophylactic antibiotics within 30 to 60 minutes before caesarean has been highly recommended, yet its implementation in hospitals varies considerably. This research aimed to analyze the cost-effectiveness of prophylactic antibiotics given a single dose versus multiple doses during caesarean section surgery. A retrospective observational study with a crosssectional design involved pregnant women undergoing caesarean section and receiving a ceftriaxone single dose before surgery (Group 1) versus those receiving multiple ceftriaxone doses (Group 2). The study calculated direct medical costs (hospital perspective), with surgical site infection (SSI) as the effectiveness parameter. The chi-square test was used to compare SSI between the two groups. There were 806 patients (group 1) and A total of 250 patients (Group 2) met the inclusion criteria. Analysis of total cost revealed no significant difference between both groups (approximately IDR 13,000,000/patient), yet patients receiving prolonged Ceftriaxone were associated with significantly higher antibiotic costs (p-0.000). The study documented 1.2% SSI in Group 1 and 0.8% in Group 2 (p=0.742). Calculation of the incremental cost-effectiveness ratio found that an extra IDR 3,278,000 was needed to provide additional success to prevent SSI by administering multiple doses of ceftriaxone. In conclusion, a single dose prophylactic antibiotic provides comparable efficacy to a multiple-dose regimen, but at a lower cost.
Evaluasi Penggunaan Antibiotika Pada Pengobatan Sepsis Neonatal Dengan Metoda Gyssens di RSAD Salak Bogor Tahun 2018 Patminingsih, Nanik; Ratih Laksmitawati, Dian; Utami Ramadaniati, Hesty
Syntax Literate Jurnal Ilmiah Indonesia
Publisher : CV. Ridwan Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (723.942 KB) | DOI: 10.36418/syntax-literate.v5i7.1468

Abstract

Sepsis merupakan disfungsi organ yang mengancam kehidupan yang diakibatkan oleh disregulasi imun terhadap infeksi. Pemberian antibiotika yang sesuai merupakan salah satu kriteria dalam tata laksana sepsis. Penelitian ini bertujuan untuk mengevaluasi penggunaan antibiotika pada pasien sepsis neonatal. Penelitian dilakukan secara obsevasi analitik dengan alur prospektif. Sebanyak 34 sampel pasien sepsis neonatal dilakukan pemantauan terapi obat. Karakteristik dominan bayi yang mengalami sepsis adalah bayi laki-laki dengan prosentase 59%, terdapat 62% Berat Badan Bayi Cukup (BBLC), 59% jenis sepsis Early Onset Sepsis (EOS), kehamilan cukup bulan 79% dan riwayat persalinan normal 62%. Penggunaan antibiotika terbanyak adalah kombinasi seftriakson-gentamisin sebanyak 50%, kombinasi ampisilin-gentamisin sebagai lini pertama sebanyak 35%, ceftriakson tunggal 9% serta ceftazidim tunggal dan kombinasi seftazidim-gentamisin masing-masing 3%. Hasil evaluasi Gyssens menunjukkan hasil kerasionalan antibiotika 18%, ketidakrasionalan 82%. Hasil statistic menunjukkan bahwa nilai sig yang didapat sebesar 0.912 > alpha 0.05. Hal ini menunjukkan H0 diterima atau tidak adanya hubungan rasionalitas dengan lama hari sembuh. Penggunaan rasional atau tidaknya tidak ada hubungannya dengan seorang pasien lebih cepat atau lebih lama dalam penyembuhan. Kata kunci : Penggunaan antibiotika; sepsis neonatal; metoda Gyssens
Co-Authors Andam Dewi Pertiwi Bayu Pertiwi Christine Meidiawati Dian Ratih Laksmitawati Dwirani Amelia Koswara Rahajeng, Suny Neni Rahmani Nurita Andayani Patminingsih, Nanik Prih Sarnianto Prih Sarnianto Prih Sarnianto Sarnianto, Prih Sesilia Andriani Keban Sutarno Zata Yumni Azizah