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Review : Pendekatan Metabolomik Untuk Authentifikasi Kehalalan Daging Berdasarkan Cara Penyembelihannya Maritha, Vevi; Kartini, Puri Ratna; Basy, Lukman La
Pharmed: Journal of Pharmaceutical Science and Medical Research Vol 6, No 2 (2023)
Publisher : Universitas PGRI Madiun

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25273/pharmed.v6i2.17979

Abstract

Halal meat is a concern in many countries, including Indonesia. This is because halal meat can not only be accepted by Muslims but also by non-Muslims. The process of slaughtering meat is one of the critical points to authenticate the halalness of meat. Halal meat that is slaughtered not according to sharia will make meat that should be halal become non-halal. Therefore, a method is needed that is able to authenticate the halalness of meat based on the slaughter process, through a metabolomics approach. Metabolites are the result of gene expression with the environment so that the metabolites of meat slaughtered not according to sharia will be different from metabolites that are slaughtered according to sharia. To facilitate visualization of halal authentication, chemometric analysis is needed. Chemometrics will reduce a lot of metabolite data to be simpler so that it is easier to understand. The metabolomics approach combined with chemometrics will be an alternative method that can be used to authenticate the halalness of meat based on the slaughter process.
TELANG FLOWER KOMBUCHA SOLID BATH SOAP AS A HALAL AND ANTIMICROBIAL PHARMACEUTICAL BIOTECHNOLOGY PRODUCT Rezaldi, Firman; Surya, Meylissa Servita; Maritha, Vevi; Ginanjar, Iin Hasan; Nurmaulawati, Rina
International Journal Mathla’ul Anwar of Halal Issues Vol. 4 No. 1 (2024): Maret
Publisher : Universitas Mathla’ul Anwar Banten

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30653/ijma.202441.97

Abstract

Excellent health is part of having immunity which tends to be stable, where normal flora is the most important parameter in increasing the body's resistance. Normal flora that is not well controlled can also increase the body's immune system to become threatened so that disease and infection have the potential to attack each individual. Smelly armpits are a sign of disease or Staphylococcus hominis infection. Women's intimate organs experiencing vaginal discharge is a sign of disease or infection caused by Candida albicans. The solution that can be offered to inhibit the growth of these two microbes is to bathe using herbal soap that is environmentally friendly and antimicrobial, namely solid bath soap made from the active ingredient of telang flower kombucha. This research aims to produce environmentally friendly pharmaceutical biotechnology products in the form of solid bath soap formulations and preparations made from the active ingredient of telang flower kombucha. This research is a laboratory experiment by making a solid bath soap base without active substances and a solid bath soap made from the active ingredient of butterfly pea flower kombucha with sugar concentrations including 20%, 30% and 40%. This research has proven that solid bath soap with the active ingredient telang flower kombucha at a concentration of 40% is significantly different as a pharmaceutical biotechnology product in inhibiting the growth of the two test microbes, both bacteria that cause underarm odor and pathogenic fungi that cause vaginal discharge in women's intimate organs at concentrations of 20% and 30%. based on one-way ANOVA analysis with a P value <0.05. This research can be proven and concluded that telang flower kombucha solid bath soap at a concentration of 40% is an effective treatment as a pharmaceutical biotechnology product and as an antimicrobial for both bacteria that cause underarm odor and pathogenic fungi that cause vaginal discharge in women's intimate organs
Formulasi dan Sediaan Spray Kombucha Bunga Telang sebagai Produk Bioteknologi Farmasi dan Antifungi Fusarium Oxyporum Rezaldi, Firman; Kartina, Kartina; Susiyanti, Susiyanti; Maritha, Vevi; Kolo, Yuliana; Mubarok, Syariful; Fathurrohim, Muhammad Faizal
Jurnal Dunia Farmasi Vol 8, No 2 (2024): Edisi April
Publisher : LPPM Institut Kesehatan Helvetia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33085/jdf.v8i2.6056

Abstract

Pendahuluan: Formulasi dan sediaan spray secara alami dapat dimanfaatkan dari larutan fermentasi kombucha bunga telang sebagai salah satu upaya dalam menghambat pertumbuhan jamur patogen penyebab penyakit maupun infeksi yang terjadi pada tanaman komoditas hortikultura. Tujuan: Membuat formulasi dan sediaan Spray dengan bahan aktif larutan fermentasi kombucha bunga telang pada konsentarsi yang berbeda dalam menghambat pertumbuhan Fusarium oxyporum. Metode: Penelitian ini bersifat eksperimental laboratorium yaitu dengan cara membuat formulasi dan sediaan spray dengan bahan aktif larutan fermentasi kombucha bunga telang pada konsentrasi gula sebesar 20%, 30%, dan 40%. Hasil: Konsentrasi gula pada sediaan spray kombucha bunga telang berbeda nyata dengan konsentrasi 20% dan 40% sebagai produk bioteknologi farmasi dan antifungi Fusarium oxyporum penyebab penyakit dan infeksi pada tanaman komoditas hortikultura dengan rata-rata diameter zona hambat adalah sebesar 14,03 mm yang termasuk kategori kuat.  Kesimpulan: Bahwa semakin tinggi konsentrasi gula sebagai substrat pada formulasi dan sediaan spray dengan bahan aktif larutan fermentasi kombucha bunga telang, maka semakin berpotensi juga sebagai produk bioteknologi farmasi dalam menghambat pertumbuhan Fusarium oxyporum.
Telang Flower Kombucha Hand Wash Soap as a Pharmaceutical and Antibacterial Biotechnology Product isolated from Cilegon Coconut Market Vegetable Waste: Sabun Cuci Tangan Kombucha Bunga Telang Sebagai Produk Bioteknologi Farmasi dan Antibakteri yang Diisolasi dari Limbah Sayuran Pasar Kelapa Cilegon Rezaldi, Firman; Yenny, Ratna Fitri; Maritha, Vevi; Andry, Muhammad; Pamungkas, Barolym Tri
Journal of Applied Plant Technology Vol 3 No 1 (2024): Journal of Applied Plant Technology (JAPT)
Publisher : Agrotechnology Study Program, Faculty of Agriculture, Wijaya Kusuma Surabaya University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30742/2ww4vj55

Abstract

Vegetable waste that is widely distributed in the Cilegon Banten coconut market contains pathogenic bacteria including Staphylococcus aureus, Listeria monocytogenes, Salmonella thypi, and Escherichia coli. These pathogenic bacteria have the potential to cause extraordinary events (KLB), especially food poisoning. The appeal for vegetable waste managers at the Cilegon Banten coconut market to inhibit the growth of pathogenic bacteria is to adopt a clean lifestyle by diligently washing hands with antibacterial hand washing soap after disposal of widely exposed vegetable waste along with a mixture of other infectious waste. Hand washing soap with the active ingredient telang flower kombucha in this study correlated positively in inhibiting the growth of four pathogenic bacteria. Research results have proven that hand washing soap at a concentration of 40% is the best antibacterial treatment.
FORMULASI SEDIAAN SPRAY ALAMI PADA KOMBUCHA BUNGA TELANG SEBAGAI PRODUK BIOTEKNOLOGI FARMASI DAN ANTIFUNGI PADA TANAMAN KOMODITAS HORTIKULTURA JENIS KENTANG (Solanum tuberosum L) Rezaldi, Firman; Maritha, Vevi; Yenny, Ratna Fitry; Saifullah, Ipul; Sugiono, Sugiono; Rohmatulloh, Rizal; Munir, Misbakhur; Setiawan, Usman; Mubarok, Syariful; Kusumiyati, Kusumiyati
AGRIBIOS Vol 22 No 1 (2024): JUNI
Publisher : Program Studi Agribisnis Fakultas Pertanian

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36841/agribios.v22i1.4600

Abstract

Tanaman kentang memiliki manfaat sebagai sumber karbohidrat, sehingga dapat dimanfaatkan sebagai menu pengganti nasi. Gagalnya panen pada tanaman kentang disebabkan oleh faktor faktor biotik yang sangat potensial dalam menyerang tanaman kentang sehingga para petani sulit dalam memenuhi permintaan pasar dalam jangka waktu terkendali maupun tidak terkendali. Fungi patogen penyebab busuk pada tanaman kentang yaitu spesies Phytophthora infestans. Fungi patogen penyebab bercak cokelat pada tanaman kentang berupa Ralstonia solanacearum merupakan spesies fungi patogen penyebab layu pada daun tanaman kentang, sehingga dibutuhkan antibiotik secara natural dari kombucha bunga telang yang cukup ramah lingkungan dengan pertimbangan adanya penggunaan pestisida secara kimiawi cukup potensial dalam merusak lingkungan budidaya tanaman. Penelitian ini bersifat eksperimental laboratorium yaitu dengan cara membuat formulasi dan sediaan spray kombucha bunga telang pada konsentrasi 20%, 30%, dan 40%, menyediakan aquadest steril yang dirancang sebagai kontrol negatif, menyediakan antibiotik pasaran sebagai kontrol positif. Tahapan tahapan penelitian ini meliputi persiapan bunga telang, kultur awal kombucha, fermentasi kombucha bunga telang, menguji daya hambat pertumbuhan fungi patogen dari masing-masing formulasi dan sediaan spray kombucha bunga telang, dan analisis data. Hasil penelitian ini telah terbukti bahwa seluruh formulasi dan sediaan kombucha bunga telang dapat dimanfaatkan sebagai antifungi bagi tanaman kentang yang cukup potensial dalam diserang fungi patogen, sehingga perlu diberikan edukasi bagi petani dalam pemanfaatan kombucha bunga telang untuk diperankan sebagai minuman probiotik peningkat sistem imun maupun sediaan spray natural yang ramah lingkungan.
Evaluasi Kualitas Air pada Sistem Pendinginan PT. XYZ Surabaya: Studi Kasus Cooling Water Nisa, Nur Ihda Farikhatin; Fanani, Nurull; Maritha, Vevi
Journal of Chemical Process Engineering Vol. 8 No. 2 (2023): Journal of Chemical Process Engineering
Publisher : Fakultas Teknologi Industri - Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/jcpe.v8i2.975

Abstract

Sistem pendinginan merupakan komponen penting dalam berbagai proses industri yang mempunyai peranan untuk menjaga suhu peralatan dan kinerja proses agar tetap optimal. Kualitas air yang digunakan dalam sistem ini harus mampu memastikan efisiensi operasional dan meminimalkan risiko kerusakan pada peralatan. Analisis kualitas air pada cooling water menjadi sangat penting untuk memantau dan mengendalikan beberapa parameter kunci dalam kualitas air agar tetap dalam batas yang aman dan optimal. Tujuan dari penelitian ini adalah menganalisa kualitas cooling water pada PT. XYZ Surabaya berdasarkan beberapa parameter diantaranya pH, TDS, turbidity, M-alkalinitas, Ca-hardness, total-hardness, LSI (Langelier Saturation Index), dan RSI (Ryznar Stability Index). Metode penelitian yang digunakan terdiri dari tiga tahapan yaitu tahap pengambilan sampel, tahap persiapan, dan tahap analisis. Pengambilan sampel dilakukan dengan mengambil sampel cooling water pada pabrik tersebut. Sedangkan tahap persiapan dilakukan dengan melakukan kalibrasi terhadap alat-alat instrumentasi yang digunakan. Selanjutnya dilakukan tahap analisa terhadap beberapa parameter kualitas air tersebut. Hasil analisa menunjukkan bahwa cooling water PT. XYZ Surabaya memiliki nilai pH, TDS, turbidity, M-alkalinitas, Ca-hardness, total-hardness, LSI, dan RSI berturut-turut sebesar 6,54; 544 ppm; 1,34 NTU; 236,88 ppm; 62 ppm; 16 ppm; -0,77; dan 8,1. Dari hasil yang diperoleh menunjukkan bahwa air memiliki tingkat korosifitas yang tinggi namun tidak terbentuk kerak.
ANTI-BACTERIAL ACTIVITY TEST OF ETHANOL EXTRACTS AND ETHLACETATE FRACTION FROM THE EXTRACT OF JATROPHA CURCAS L. LEAVES AGAINST STAPHYLOCOCCUS AUREUS Wulandari, Sekar; Erikania, Susanti; Maritha, Vevi
Journal of Vocational Health Studies Vol. 5 No. 1 (2021): July 2021 | JOURNAL OF VOCATIONAL HEALTH STUDIES
Publisher : Faculty of Vocational Studies, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jvhs.V5.I1.2021.31-38

Abstract

Background: Staphylococcus aureus is a gram-positive bacteria that can cause infection. One of the plants that has antibacterial activity is jatropha leaves which contain flavonoids, saponins, tannins, alkaloids, steroids and polyphenols. Purpose: To determine the antibacterial activity of ethanol extract and ethyl acetate fraction with concentrations of 30%, 60% and 100% against Staphylococcus aureus bacteria. Method: The method for extracting jatropha leaves is maceration with 96% ethanol solvent and the fractionation method, namely liquid-liquid fractionation with ethyl acetate solvent. Antibacterial activity test was carried out in vitro with the disc diffusion method and compared the mean zone of inhibition of each treatment with a positive control (gentamicin 10 μg). Result: The results showed that the ethanol extract and ethyl acetate fraction of jatropha leaves had a strong resistance response, while the positive control gave a very strong inhibitory response to the growth of S. aureus bacteria. Based on the one way ANOVA test, ethanol extract and ethyl acetate fraction showed a significant difference from each treatment with a significant value (P=<0.05). Conclusion: The ethanol extract of Jatropha leaves can inhibit the growth of S. aureus bacteria at a concentration of 100% (18.28 ± 0.50 mm), 100% concentration of ethyl acetate fraction (15.10 ± 0.12 mm). The ethanol extract provided the best inhibition power, namely 18.28 ± 0.50 mm and a positive control 21.82 ± 0.092 mm.
ANTIBACTERIAL ACTIVITY OF MANGOSTEEN BARK FRACTION (GARCINIA MANGOSTANA L.) SALMONELLA TYPHI ATCC 13311 Anggraini, Salmah Wilujeng; Erikania, Susanti; Maritha, Vevi
Journal of Vocational Health Studies Vol. 5 No. 3 (2022): March 2022 | JOURNAL OF VOCATIONAL HEALTH STUDIES
Publisher : Faculty of Vocational Studies, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jvhs.V5.I3.2022.139-145

Abstract

Background: Typhoid fever is caused by Salmonella typhi bacterial infection which spreads via the faecal-oral route and has epidemic potential. Salmonella typhi is a Gram-negative bacterium in the Enterobacteriaceae family. Currently, the use of natural ingredients can be an alternative treatment for typhoid fever, one of which is the mangosteen stem skin (Garcinia mangostana L.). Purpose: To determine the antibacterial activity of mangosteen stem skin fraction against Salmonella typhi ATCC 13311. Method:The maceration method was selected using methanol solvent and fractionation by ECC using ethyl acetate and n-hexane as solvents. This study used five treatments (fraction with a concentration of 20%, 40%, 80%, chloramphenicol 30µg as a positive control, and DMSO as a negative control) which tested their antibacterial activity against Salmonella typhi ATCC 13311 by disc diffusion. Result: The results showed that the ethyl acetate fraction of mangosteen stem skin had the greatest average inhibition zone, that is 13.86 ± 0.72 mm compared to the n-hexane fraction of mangosteen stem skin with an inhibition zone of 10.43 ± 0.73 mm. The data obtained were then analyzed with One-way ANOVA. Conclusion: The results obtained were p=0.000 (sig <0.05), indicating that there was a significant difference between the ethyl acetate fraction and the n-hexane fraction with 20%, 60%, and 80% concentrations with positive control