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All Journal Jurnal Wiyata : Penelitian Sains dan Kesehatan Journal Of Holistic Nursing Science Jurnal Farmasi dan Sains Indonesia (JFSI) Medical Sains : Jurnal Ilmiah Kefarmasian Pharmacy Genius Ad-dawaa: Journal Of Pharmacy Jurnal Kesehatan Bakti Tunas Husada Daarul Ilmi: Jurnal Pengabdian Kepada Masyarakat Medical Sains : Jurnal Ilmiah Kefarmasian
Davit Nugraha
STIKes Muhammadiyah Ciamis
Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary Other

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Journal : Ad-dawaa: Journal Of Pharmacy

 1 
Formulation and Evaluation of Catfish ( Calias Sp ) Albumin Extract Ointment with Variations of Basis Erik Risnawan; Davit Nugraha
Ad-Dawaa : Journal of Pharmacy Vol. 1 No. 1 (2023): Ad-Dawaa: Journal of Pharmacy (May 2023)
Publisher : LPPM STIKes Muhammadiyah Ciamis

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52221/dwj.v1i1.220

Abstract

Catfish (Clarias sp) contains albumin which is an important protein needed by the human body, especially in the process of healing diseases. Giving this catfish extract functions as a nutrient, it is hoped that this nutrition can improve nutrition, increase the immune system and speed up the wound healing process or post surgery. This research is an experimental research, in which the albumin ointment formulation of catfish (clarias sp) extract was carried out, with variations of vaselin flavum and adeps lanae ointment bases in three formulations namely formulation 1, formulation 2 and formulation 3. The results of catfish extract (clarias sp) were then formulated in the form of an ointment. Then an evaluation of physical properties was carried out including organoleptic evaluation, homogeneity test, spreadability test, adhesion test, pH test. The results showed that the albumin extract ointment for catfish (Clarias sp) with variations in ointment base made a difference to the evaluation of albumin extract for catfish (Clarias sp) which included organoleptic tests (soft shape, white to yellow), homogeneity test (has round particles, irregular, no foreign particles), spreadability test (FI, 5.16cm: FII, 5.23cm: FIII, 5.06cm), adhesion test (FI, 3.19 seconds, FII 2.27 seconds, FIII 3.24 seconds), pH test (FI 6, FII 6, FIII 6). The conclusion that the vaseline flavum ointment combined with adeps lanae from catfish albumin extract meets the quality consists of an evaluation. homogeneity test, organoleptic test, adhesion test, spreadability test and pH test.
Albumin Identification in Catfish ( Clarias sp ) Using Spectrophotometry UV-VIs Perti Fitriani; Davit Nugraha
Ad-Dawaa : Journal of Pharmacy Vol. 1 No. 1 (2023): Ad-Dawaa: Journal of Pharmacy (May 2023)
Publisher : LPPM STIKes Muhammadiyah Ciamis

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52221/dwj.v1i1.223

Abstract

Albumin is a simple protein with globular protein molecules. Albumin is water soluble and can be coagulated with heat. Albumin solution in water can be precipitated by adding ammonium sulfate until saturated. Albumin functions to regulate the osmotic pressure in the blood, maintain the presence of water in the blood plasma so that it can maintain the volume of blood in the body and as a means of transportation and transportation. Catfish contains 15.6 grams of high-quality protein in each fish so that it can meet the needs of the amino acids needed by the body. The high-quality protein in catfish helps the body build lean brain mass and the protein content in catfish also helps increase the effectiveness of immune function. The purpose of this study was to determine albumin levels in catfish by extracting catfish meat using the oven method and determining the maximum albumin wavelength. In the identification test with the heating method and UV-Vis spectrophotometry test. This research method uses the experimental method. The extraction results were then heated in an oven to observe coagulation and determine the wavelength using UV-Vis spectrophotometry using Bovine Serum Albumin (BSA) as a reference solution and Bromocressol green as a reagent. The conclusion of this study is that catfish meat extract was coagulated using the oven method and maximum absorption was obtained at a wavelength of 625 nm using UV-Vis spectrophotometry.
Formulation and Evaluation of Gel Mask Peel Off Moringa Leaf Extract (Moringa oleifera Lam) Santi Agustina; Anna L Yusuf; Davit Nugraha
Ad-Dawaa : Journal of Pharmacy Vol. 1 No. 1 (2023): Ad-Dawaa: Journal of Pharmacy (May 2023)
Publisher : LPPM STIKes Muhammadiyah Ciamis

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52221/dwj.v1i1.224

Abstract

Peel-off gel mask is a practical mask, after drying the mask can be directly removed or removed without causing pain. This mask can also restore freshness and softness of the skin, even with regular use it can reduce fine wrinkles on facial skin. Moringa plants contain antioxidants, especially the leaves that contain flavonoids, causing Moringa leaves to be used as a source of natural antioxidants. The research method used is an experimental method with peel off gel mask preparation samples of Moringa leaf extract with various concentrations of 0% (F0), 5%(F1), 10%(F2), and15% (F3). Data analysis using One Way Anova test with 95% confidence level of significance = 0.05. Evaluation of the peel off gel mask preparation includes organoleptic test, homogeneity test, pH test, viscosity test, dispersibility test, adhesion test, dry time test and syneresis test. The results of the research F0, F1, F2 and F3 met the standard of the tests carried out such as organoleptic tests, pH tests, dispersibility tests, adhesion tests, dry time tests, and syneresis tests. The results of the One Way Anova statistical test for the pH test obtained a P-Value value of 0.63> 0.05, the dispersion test obtained a P-Value value of 0.02 0.05, the drying time test obtained a P-Value value of 0.00 (0.05) while the test dispersion and syneresis test there is an effect of giving concentration variations with a significance value of P < (0.05).
Narrative Review: Optimation of Ethanol as a Solvent for Flavonoid Compounds in Papaya Leaf Extraction Davit Nugraha; Anna L Yusuf; Panji Wahlanto
Ad-Dawaa : Journal of Pharmacy Vol. 1 No. 2 (2023): Ad-Dawaa: Journal of Pharmacy (November 2023)
Publisher : LPPM STIKes Muhammadiyah Ciamis

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52221/dwj.v1i2.496

Abstract

Ethanol is widely used as a distiller of secondary metabolite compounds. Ethanol very well dissolves secondary metabolite compounds including flavonoids group compounds including for papaya (Carica papaya L.) leaf extraction. This review was conducted to examine solvent optimization that has been used in various original studies. The method of searching scientific journal article using PubMed and MDPI using keyword “extraction and ethanol and flavonoid and carica papaya leaf” with the inclusion criteria of 2018 – 2023 article, free full text and not review articles, the number of article obtained was 3 articles. The optimal concentration of ethanol as a flavonoid extract solven is 70 % ethanol at temperatures from 30 °C – 50°C with a time range of 10 – 48 hours of immersion.
Co-Authors Ade Fitriani, Ade Andhika Nor Hendryawan Anggoro Wicaksono Anisa Firdaus, Fidya Anna L Yusuf Anna Lesmanasari Yusuf Anna Yusuf Anna Yusuf Ariyanto, Heri Chela Tiara Dewi desi karningsih Dini Umayati Dona Suzana Erik Risnawan Fara Azzahra Farah A Himah Febriana Astuti Henri Setiawan Ilham Alifiar Indriastuti, Marlina Kusmini Kusmini Laela Tri Fadila Lestari, Nina Indri Muhammad Irham Muhammad Jafar Shodiq Nantia Khaerunnisa, Reffi Nova Zahra Nurunnisa Mentari Nurunnisa Mentari panji wahlanto Perti Fitriani R, Susan Sintia Rafiastiana Capritasari Rian Ismail Santi Agustina Siti Rahmah KR Siti Rahmah Kurnia Ramdan Tiyas Putri Nurgraheni Veri Nugraha Via Fitria Via Fitria Widhy Rahmadilla Garnadi Zulkifli Halid