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All Journal Jurnal Kesehatan Islam : Islamic Health Journal Alauddin Law Development Journal (ALDEV) CURRENT INTERNAL MEDICINE RESEARCH AND PRACTICE SURABAYA JOURNAL Indian Journal of Forensic Medicine & Toxicology Jurnal Penelitian Sains dan Kesehatan Avicenna
Suhartati
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Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health Social Sciences

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Journal : Jurnal Kesehatan Islam : Islamic Health Journal

 1 
Efek Pemberian Ekstrak Etanol Daun Jarak Merah (Jatropha gossypiifolia L.) terhadap Kadar Glukosa Darah Puasa, Kadar Insulin Serum dan HOMAIR pada Model Tikus DM Tipe 2 Nugroho Wibisono; Achmad Basori; Suhartati
Jurnal Kesehatan Islam : Islamic Health Journal Vol. 11 No. 2 (2022): Jurnal Kesehatan Islam : Islamic Health Journal
Publisher : Publikasi oleh Fakultas Kedokteran Universitas Islam Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33474/jki.v11i2.19225

Abstract

Abstract. Jatropha gossypiifolia L. is a medicinal plant from theEuphorbiaceae family. Jatropha gossypiifolia L. leaves have somemedicinal properties, but their effect on antidiabetics mechanisms isstill unclear. Jatropha gossypiifolia leaves have some activecompounds such as alkaloid, flavonoid, phenol, saponins, tannins,steroid, terpenoid, and triterpenoid. The presentstudy was designedto analyze effect of Jatropha gossypiifolia leaves extract activecompounds on fasting blood glucose levels, serum insulin levels andHOMA-IR. The design of thisresearch istrue experimental with posttest only control group design with independent variables includinga high-fat diet, streptozotocin injections, Jatropha gossypiifolia L.leaves extract in doses of 60, 120, dan 240 mg/kg and dependentvariables including fasting blood glucose levels, serum insulin levels,and HOMA-IR. Based on this study, there were a significantlydifferent between fasting blood glucose levels and HOMA-IR controlgroups than the extract groups. It can be concluded that Jatrophagossypiifolia L. leaves extract has effect on fasting blood glucoselevels, serum insulin levels and HOMA-IR on DM type 2 rat models.
Co-Authors Abd Basir Achmad Basori Arbiyah Arifian Hardi Putri Ratnani Ema Qurnianingsih Emy Febrianti Kahar Erniwati Daranga Esse Tendry Nelly Fath Irtaniyah R Fath Irtaniyah Rahman Ira Humairah Isra Wati Lina Lukitasari, M.Si Mariani Nugroho Wibisono Nurina Hasanatuludhhiyah Prabowo, Gwenny Ichsan Rosalina Togala Siti Khaerunnisa