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All Journal Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Folia Medica Indonesiana WMJ (Warmadewa Medical Journal) HIGEIA (Journal of Public Health Research and Development) Qanun Medika - Medical Journal Faculty of Medicine Muhammadiyah Surabaya Jurnal Medik Veteriner Biomolecular and Health Science Journal CURRENT INTERNAL MEDICINE RESEARCH AND PRACTICE SURABAYA JOURNAL Indian Journal of Forensic Medicine & Toxicology
Prabowo, Gwenny Ichsan
Departement Of Biochemistry, Medicine Faculty, Universitas Airlangga, Surabaya,
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health Veterinary Other

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TINGKAT PENDIDIKAN BUKAN MERUPAKAN PREDIKTOR RISIKO DIABETES BERDASARKAN SKORING AMERICAN DIABETES ASSOCIATION Agustianto, Rafiv Fasya; Mudjanarko, Sony Wibisono; Prabowo, Gwenny Ichsan
HIGEIA (Journal of Public Health Research and Development) Vol 4 No 1 (2020): HIGEIA: January 2020
Publisher : Jurusan Ilmu Kesehatan Masyarakat, Fakultas Ilmu Keolahragaan, Universitas Negeri Semarang, Indonesia

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Abstract

ABSTRAK Jawa Timur termasuk 10 besar provinsi dengan prevalensi diabetes melitus (DM) tertinggi di Indonesia. Penelitian ini bertujuan untuk menganalisis hubungan antara tingkat pendidikan dan risiko diabetes di Surabaya. Penelitian ini merupakan suatu studi korelasi analitik dengan metode cross sectional, dilaksanakan pada tanggal 9 Desember 2018 dengan metode skoring berdasarkan kuesioner American Diabetes Association (ADA). Skor < 5 diklasifikasikan sebagai risiko rendah, sedangkan skor ? 5 dikategorikan sebagai risiko tinggi menderita diabetes melitus (DM). Data diproses dengan uji analisis chi-square menggunakan perangkat lunak IBM SPSS Statistic 23. Sebanyak 113 subjek terlibat dalam penelitian ini, dengan 92 orang di antaranya memenuhi kriteria inklusi. Secara keseluruhan, 54 dari 92 subjek termasuk kelompok berisiko tinggi (58,70%), dengan 34 orang di antaranya berpendidikan rendah (62,96%). Mayoritas subjek adalah wanita (76,09%) dan lansia berusia lebih dari 60 tahun (34,78%). Secara statistik, hasil penelitian ini menunjukkan bahwa tingkat pendidikan bukan merupakan prediktor risiko diabetes berdasarkan skoring American Diabetes Association (p> 0,05), namun distribusi data menunjukkan prevalensi diabetes lebih banyak terdapat pada subjek berpendidikan rendah, wanita, dan lansia. ABSTRACT East Java is among the top 10 provinces with the highest prevalence of diabetes mellitus (DM) in Indonesia. This study aims to analyze the relationship between education level and diabetes risk in Surabaya. This cross-sectional study was conducted on December 9, 2018, with scoring method based on American Diabetes Association (ADA) questionnaire. Score < 5 is classified as low risk, while score ? 5 is categorized as high risk of suffering from diabetes mellitus (DM). Data were processed by chi-square analysis using IBM SPSS Statistics 23 software. A total of 113 subjects were involved in this study, with 92 of them fulfilling the inclusion criteria. Overall, 54 of 92 subjects were having high-risk (58.70%), 34 of them were low-educated (62.96%). Most of subjects were women (76.09%) and elderly aged over 60 years (34.78%). Statistically, this study indicates that education level is not a predictor of diabetes risk based on American Diabetes Association score (p> 0.05), however data distribution indicates diabetes prevalence was higher in low-educated, women and elderly subjects.  
Socialization Program for Prevention and Early Detection of Congenital Hearing Loss in the Families of Deaf School children Gwenny Ichsan Prabowo; Citrawati Dyah Kencono Wungu; Retno Handajani; Nyilo Purnami; Fis Citra Ariyanto
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 4 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i4.16878

Abstract

Objective: socializing hearing loss examination and early detection to patients and their families in deaftype B schools. Methods: A community service program in the form of socialization was performed to thefamily of patients with hearing loss in deaf school type B, Surabaya, Indonesia. Pretest and posttest wereconducted to determine the initial understanding and post socialization knowledge of these people. We alsoasked the participants to fill on a questionnaire regarding the possible causes of the hearing loss (familyhistory, drug use, history of disease, and history of head trauma). Results: Based on the summary of pretestand posttest from the participants, an increase in participants’ knowledge of hearing lost was found. Thisactivity was attended by 90 family members of 37 patients with hearing loss. Pre and post test results. Theresults of the questionnaire showed that 94.59% of the patients came from Javanese ethnicity. As many as21.62% of patients had a family history of hearing loss, and even 2 patients had a father, mother, and siblingwith hearing loss. A total of 18.92% had a history of using ototoxic drugs, 16.22% had a history of maternalRubella infection during pregnancy, and 2.7% had a history of head trauma. Conclusion: Socializationprogram was effective to increase knowledge of congenital hearing loss for family of deaf schoolchildren.The result of the questionnaire showed that deaf schoolchildren had several risk factors for the occurrenceof hearing loss. Similar program can be performed in communities in other areas to increase prevention andearly detection of hearing loss in Indonesia.
Tingkat Pendidikan Bukan Merupakan Prediktor Risiko Diabetes Berdasarkan Skoring American Diabetes Association Agustianto, Rafiv Fasya; Mudjanarko, Sony Wibisono; Prabowo, Gwenny Ichsan
HIGEIA (Journal of Public Health Research and Development) Vol 4 No 1 (2020): HIGEIA: January 2020
Publisher : Jurusan Ilmu Kesehatan Masyarakat, Fakultas Ilmu Keolahragaan, Universitas Negeri Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

ABSTRAK Jawa Timur termasuk 10 besar provinsi dengan prevalensi diabetes melitus (DM) tertinggi di Indonesia. Penelitian ini bertujuan untuk menganalisis hubungan antara tingkat pendidikan dan risiko diabetes di Surabaya. Penelitian ini merupakan suatu studi korelasi analitik dengan metode cross sectional, dilaksanakan pada tanggal 9 Desember 2018 dengan metode skoring berdasarkan kuesioner American Diabetes Association (ADA). Skor < 5 diklasifikasikan sebagai risiko rendah, sedangkan skor ≥ 5 dikategorikan sebagai risiko tinggi menderita diabetes melitus (DM). Data diproses dengan uji analisis chi-square menggunakan perangkat lunak IBM SPSS Statistic 23. Sebanyak 113 subjek terlibat dalam penelitian ini, dengan 92 orang di antaranya memenuhi kriteria inklusi. Secara keseluruhan, 54 dari 92 subjek termasuk kelompok berisiko tinggi (58,70%), dengan 34 orang di antaranya berpendidikan rendah (62,96%). Mayoritas subjek adalah wanita (76,09%) dan lansia berusia lebih dari 60 tahun (34,78%). Secara statistik, hasil penelitian ini menunjukkan bahwa tingkat pendidikan bukan merupakan prediktor risiko diabetes berdasarkan skoring American Diabetes Association (p> 0,05), namun distribusi data menunjukkan prevalensi diabetes lebih banyak terdapat pada subjek berpendidikan rendah, wanita, dan lansia. ABSTRACT East Java is among the top 10 provinces with the highest prevalence of diabetes mellitus (DM) in Indonesia. This study aims to analyze the relationship between education level and diabetes risk in Surabaya. This cross-sectional study was conducted on December 9, 2018, with scoring method based on American Diabetes Association (ADA) questionnaire. Score < 5 is classified as low risk, while score ≥ 5 is categorized as high risk of suffering from diabetes mellitus (DM). Data were processed by chi-square analysis using IBM SPSS Statistics 23 software. A total of 113 subjects were involved in this study, with 92 of them fulfilling the inclusion criteria. Overall, 54 of 92 subjects were having high-risk (58.70%), 34 of them were low-educated (62.96%). Most of subjects were women (76.09%) and elderly aged over 60 years (34.78%). Statistically, this study indicates that education level is not a predictor of diabetes risk based on American Diabetes Association score (p> 0.05), however data distribution indicates diabetes prevalence was higher in low-educated, women and elderly subjects.
Associations between P53, Transforming Growth Factor Beta-1, and Interleukin-10 Serum Levels with Advanced Liver Disease and Hepatitis B Virus Infection Citrawatidyahkencono Wungu; Mochamad Amin; Ulfa Kholili; Gwennyichsan Prabowo; Poernomoboedi Setiawan; Soetjipto; Retno Handajan
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i3.15736

Abstract

Prevention and Early Detection of Metabolic Syndrome in Household Community, Surabaya Ema Qurnianingsih; Lina Lukitasari; Ira Humairah; Siti Khaerunnisa; Gwenny Ichsan Prabowo; Suhartati
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i3.15747

Abstract

Introduction. Metabolic syndrome is a collection of factors believed to increase the risk of atherosclerosis and type 2 diabetes mellitus. The incidence of metabolic syndrome in young adults is increasing, especially in Asian countries. Therefore we need efforts to increase knowledge in society about this disease. Aim. We conducted a socialization program on prevention and early detection of metabolic syndrome in household community to increase public knowledge about this disease.Method. This program was conducted in August 2017 in Wonokromo District, Surabaya. The participants in the activity consisted of 32 people from household community. The activity consisted of blood sampling collection, body weight, and abdominal circumference measurement for risk factor assessment, pre-test, socialization of metabolic syndrome, and post-test.Results. From the results of the pre and post test, we found an increase knowledge of 76.9% participants. The laboratory test results for early detection of metabolic syndrome showed 37.5% of participants had metabolic syndrome. We also found a significant positive correlation between body weight and abdominal circumference (p = 0.000, r = 0.867). There was also a significant negative correlation between body weight and HDL (p = 0.004, r = -0.494), between abdominal circumference and HDL (p <0.05, r = -0.376), and between TG and HDL (p <0.05, r = -4.22).Conclusion. Socialization and early detection of metabolic syndrome can increase knowledge, awareness, and detection of metabolic syndrome in the household community.
IN VITRO TEST: Antimicrobial Activity Potential From Ciplukan Fruit (Physalis minima L.) Extract in Methicillin-resistant Staphylococcus aureus (MRSA) Muhammad Hanun Mahyuddin; Arifa Mustika; Gwenny Ichsan Prabowo; Deby Kusumaningrum
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 4, No 2 (2020)
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v4i2.3645

Abstract

In Indonesia, in 2006 the prevalence of infections due to MRSA was 23.5%. Physalis minima L. plants are known to have antimicrobial activity because they contain compounds withaferin A which can induce programmed cell death. This research was to determine the minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of Ciplukan (Physalis minima L.) extract in Methicillin-resistant Staphylococcus aureus (MRSA) bacteria. Dilution test with Mueller-Hinton broth medium used for measuring the minimum inhibitory concentration (MIC). Ciplukan  fruit extract was dissolved in distilled water, and poured into a test tube with a certain concentration (0.9 g/mL (90%); 0.3 g/mL (45%); 0.15 g/mL (22.5%); 0.075 g/mL (11.25%) and 0.0375 g/mL (5.625%). After being incubated for 24 hours, the bacteria in the test tube were plated on nutrient agar plates, to determine the MBC. The MIC cannot be determined, because the solution in the dilution test tube is disturbed by the color of the extract so that turbidity cannot be observed. From the observations of the minimum bactericidal concentration MBC of the Ciplukan (Physalis minima  L.) fruit extract against MRSA was in the P1 tube or equivalent to 0.9 g / ml (90%).
Distribution of Hepatitis B Virus Genotypes Among Patients at Internal Medicine Unit, Dr. Soetomo General Hospital, Surabaya Citrawati Dyah Kencono Wungu; Mochamad Amin; Ulfa Kholili; Gwenny Ichsan Prabowo; Poernomo Boedi Setiawan; Soetjipto Soetjipto; Retno Handajani
WMJ (Warmadewa Medical Journal) Vol 4 No 1 (2019): May 2019
Publisher : Warmadewa University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22225/wmj.4.1.1032.6-13

Abstract

Background: Hepatitis B virus (HBV) infection is a major health problem worldwide, especially in developing countries. The study of HBV genotypes is important to find out the diversity of HBV genotypes related to the severity of the disease, response to therapy, and clinical symptoms. Objective: This study was aimed to detect HBV genotypes in patients at Hepatology Outpatient Clinic, Dr. Soetomo Hospital Surabaya. Methods: This study was conducted on new patients at Hepatology Outpatient Clinic of Dr. Soetomo General Hospital, Surabaya in one month. Nested PCR was performed by targetting HBV surface genes. Samples with positive HBV DNA were sequenced and analysed further. Results: In this study, a total of 27 samples were obtained. The prevalence of HBV infection shown by positive HBsAg in patients with symptoms of liver disease was 55.55% (15/27 patients). Based on the results of electrophoresis from PCR products, positive HBV DNA was obtained in these 15 patients (100%). After sequencing samples with positive HBV DNA, genotype B of Indonesian strain was found to be predominant genotype (100%). Subgenotype analysis showed that 7/15 samples had B3 subgenotype (46.67%). Conclusion: In patients at Hepatology Outpatient Clinic of Dr. Soetomo General Hospital, Surabaya, the prevalence of HBV infection was high (55.55%) and genotype B was predominant. In Surabaya, HBV genotype infection still remained like the previous pattern, although in Indonesia there have been many inter-island and ethnic migration. Further similar studies are needed to obtain the diversity of other HBV genotypes.
The frequency of DISC1 Leu607Phe gene polymorphism in schizophrenia patients at Dr. Soetomo General Hospital Surabaya gwenny Ichsan Prabowo; Margarita Maria Maramis; Erikavitri Yulianti; Afrina Zulaikah; Zain Budi Syulthoni; Hendy Muagiri Margono; Retno Handajani
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 50, No 1 (2018)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (359.763 KB) | DOI: 10.19106/JMedSci005001201802

Abstract

Schizophrenia is a common health problem in the world, including in Indonesia.Polymorphism of gene disrupted in schizophrenia 1 (DISC1) Leu607Phe is allegedly relatedto the predisposition to schizophrenia. However, studies on the relationship betweenpolymorphism of DISC1 Leu607Phe and schizophrenia in various etnics provided differentresults. The purpose of this study was to determine the frequency of DISC1 Leu607Phegenepolymorphism and its association with treatment response in patients with schizophreniaat Department of Psychiatry, Dr. Soetomo General Hospital Surabaya. In this study, thenumber of male patients with schizophrenia was more than that of the female patients.The mean age of male patients with schizophenia was lower than that of the femalepatients. Schizophrenia patients were primarily came from Javanese ethnic with positiveand negative symptom score (PANSS) lower in male patients than that in the femalepatients. In conclusion, no DISC1 gene polymorphism at codon 607 is observed inschizophrenia patients at Dr. Soetomo General Hospital Surabaya, but the G nucleotidevariation at the number 196.339 in intron regions is found instead.
The Improvement of Community Knowledge, Attitudes and Practices After Covid-19 Socialization Siti Khaerunnisa; Irmi Syafa'ah; Citrawati Dyah Kencono Wungu; Gwenny Ichsan Prabowo; Retno Handajani; Indri Safitri; Harianto Notopuro; Ema Qurnianingsih; Lina Lukitasari; Ira Humairah; Arief Bakhtiar; Suwandito Suwandito; Susi Wahyuning Asih; Zuhrotul Eka Yulis Anggraeni; Ginanjar Sasmito Adi; Ely Rahmatika Nugrahani; Ayesie Natasha Zulka; Soetjipto Soetjipto
Folia Medica Indonesiana Vol. 57 No. 2 (2021): June
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (314.653 KB) | DOI: 10.20473/fmi.v57i2.26262

Abstract

This study determined community knowledge, attitudes, and practices after COVID-19 socialization in Rambipuji and Suci Village, Jember District, East Java, Indonesia. This study used the analytic observational design study. As many as 40 people were given socialization about COVID-19 by gathering and online. The questionnaires were completed in two parts included before-socialization and after-socialization. The questionnaire data were analyzed descriptively by calculating frequency, percentage, and inferential statistics by t-test, Spearman correlation, and chi-square test. The data analysis used IBM SPSS version 23 software. The mean and standard deviation of percentage of knowledge pre-test, knowledge post-test, high attitude, moderate attitude, low attitude, very high practice, high practice, sufficient practice, and low practice were 58.33 ± 30.97, 77.70 ± 22.52, 62.5±21.7, 31±22.2, 6.5±17.1, 65±13.8, 32.3±13.8, 1.25±2.4, 1.25±1.8, respectively. Knowledge pre-test and post-test correlated 0.819 (p=0.001) and a t-test with p=0.003. Attitudes and practices correlated with p=0.001. Socialization of COVID-19 was useful to improve the community knowledge, attitudes, and practices in Rambipuji and Suci Village, Jember District, East Java, Indonesia that could prevent the transmission and inhibit the spread of the COVID-19 pandemic in Indonesia. Furthermore, continuous encouragement of COVID-19 socialization in wide areas was recommended.
Infant Birth Weight in Mothers with Maternal Anemia at Dupak Public Health Center Surabaya Working Area in 2017 Marisabell Giovanni; Gwenny Ichsan Prabowo; Widati Fatmaningrum
Biomolecular and Health Science Journal Vol. 2 No. 1 (2019): Biomolecular and Health Science Journal
Publisher : Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (250.507 KB) | DOI: 10.20473/bhsj.v2i1.13239

Abstract

Introduction: Anemia in pregnant women is a factor that directly affects the incidence of LBW and can be measured to determine nutritional status during pregnancy. This research is to determine the association of infant birth weight in mothers with maternal anemia at Public Health Center working area in Surabaya.Methods: This research was a cross-sectional approach The sample of this research were 75 pregnant women at Dupak Public Health Center in Surabaya City in 2017 taken by total sampling technique. The data used was taken from the 2017 mother cohort book.Results: The incidence of LBW at Dupak Public Health Center Surabaya working area in 2017 was 12 people (16%). The incidence of anemia at Dupak Public Health Center Surabaya working area in 2017 was 38 people (50.7%). The correlation between LBW and anemia in pregnancy using Chi-Square was p = 0.496.Conclusion: There was no correlation between maternal anemia and LBW There are other factors that can affect the incidence of LBW, such as body weight and maternal height, the number of parity, a short pregnancy distance, and the existence of problems in the history of previous pregnancy and childbirth.
Co-Authors Afrina Zulaikah Agustianto, Rafiv Fasya Arifa Mustika Ayesie Natasha Zulka Bakhtiar, Arief Birgitta Henny Perwitasari Citrawati Dyah Kencono Wungu Deby Kusumaningrum Deva Medisika Hertiti Dwi Susanti Ely Rahmatika Nugrahani Ema Qurnianingsih Erikavitri Yulianti Fis Citra Ariyanto Ginanjar Sasmito Adi Harianto Notopuro Hendy Muagiri Margono Indri Safitri Ira Humairah Ira Humairah Irmi Syafa'ah Karina Ayu Nilamsari Lina Lukitasari, M.Si Maramis, Margarita M. Marisabell Giovanni Mochamad Amin Muhammad Hanun Mahyuddin Nurmawati Fatimah Nyilo Purnami Poernomo Boedi Setiawan Poernomo Boedi Setiawan Poernomoboedi Setiawan Retno Handajan Retno Handajani Siti Khaerunnisa Siti Khaerunnisa SOETJIPTO Soetjipto Soetjipto Soetjipto Soetjipto Sony Wibisono Suhartati Susi Wahyuning Asih Suwandito Suwandito Ulfa Kholili Widati Fatmaningrum Zain Budi Syulthoni Zuhrotul Eka Yulis Anggraeni