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Yuliana, Depi
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Identification of Adverse Drug Reactions in Congestive Heart Failure Patients in a Tertiary Care Hospital, West Nusa Tenggara, Indonesia Lupitaningrum, Dita Marina; Ramdaniah, Putri; Yuliana, Depi
Pharmaceutical Sciences and Research
Publisher : UI Scholars Hub

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Abstract

Congestive Heart Failure (CHF) is a progressive health problem with high mortality and morbidity and has the potential to develop adverse drug reactions (ADRs). This study was conducted to determine the prevalence of potential ADRs, the types of drugs that cause ADRs, the types of ADRs, and the risk factors that affect the ADRs in CHF patients. Data were collected using medical record of hospitalized patient at the West Nusa Tenggara (NTB) Provincial Hospital, Indonesia, in 2017 to 2019. The assessment of the causality and severity of ADRs used the Naranjo algorithm and the Hartwig and Siegel scale. This study used 325 CHF patients’ data. Of 325 CHF patients, 223 patients (69%) were recorded as having ADRs with 446 total cases of ADRs, consisted of 4 (0.9%) highly probable, 187 (41.9%) probable, and 255 (57.2%) possible. The drugs that cause ADRs with a highly probable status are bisoprolol and ramipril. The most ADRs categories were level 1 (76.0%), followed by level 2 (17.3%), level 3 (6.5%), and level 4A (0.2%). The most affected organ systems were the muscles, joints, and nervous system (n=136, 37.7%), followed by renal, and gastrointestinal system. No association between ADRs with several risk factors, such as gender, age, and comorbidities. The prevalence of ADRs in CHF patients in this study was 69%, with the highly probable category in causing ADRs were bisoprolol and ramipril. ADRs that mostly occurred were in the mild category. ADRs monitoring in CHF patients is especially important to achieve optimal therapeutic results.
Hubungan Tingkat Pengetahuan Masyarakat Terhadap Perilaku Swamedikasi Putri, Tursina Kamila; Bayani, Faizul; Apriani, Laili; Yuliana, Depi
Empiricism Journal Vol. 3 No. 2: December 2022
Publisher : Lembaga Penelitian dan Pemberdayaan Masyarakat (LITPAM)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36312/ej.v3i2.1065

Abstract

Swamedikasi atau pengobatan sendiri merupakan upaya masyarakat dalam menangani keluhan penyakit yang dialami. Pengobatan sendiri akan menimbulkan masalah terhadap obat atau yang biasa disebut dengan istilah Drug Related Problems (DRP’s), hal tersebut dikarenakan kurangnya pemahaman terhadap obat dan fungsinya. Penelitian ini bertujuan untuk mengetahui hubungan tingkat pengetahuan masyarakat terhadap perilaku swamedikasi di Dusun Muara Putat Desa Pemenang Timur Kecamatan Pemenang Kabupaten Lombok Utara Tahun 2022. Penelitian ini merupakan penelitian survey analitik dengan teknik cross sectional. Pengambilan sampel menggunakan non random sampling dengan teknik pusposive sampling. Sampel yang digunakan dalam penelitian ini sebanyak 83 responden. Hasil penelitian ini menunjukan bawa responden memiliki pengetahuan tergolong rendah sebesar 4,82%, 72,29% responden tergolong sedang, dan 22,89% tergolong baik. Kemudian perilaku swamedikasi menunjukan 12,05% responden memiliki perilaku swamedikasi tergolong rendah, 62,65% responden tergolong sedang, dan 25,30% tergolong tinggi. Berdasarkan hasil uji Chi-Square diperoleh hasil yang tidak signifikan dengan nilai P value yakni sebesar 0,063 yang menunjukan bahwa terdapat hubungan yang tidak signifikan antara tingkat pengetahuan terhadap perilaku swamedikasi. Relationship between Community Knowledge Level and Self-Medication Behavior Abstract Self-medication or self-medication is a community effort in dealing with complaints of the disease they are experiencing. Self-medication will cause problems with drugs or what are commonly referred to as Drug Related Problems (DRP's), this is due to a lack of understanding of drugs and their functions. This study aims to determine the relationship between the level of public knowledge and self-medication behavior in Muara Putat Hamlet, Pemenang Timur Village, Pemenang District, North Lombok Regency in 2022. This research is an analytic survey study using a cross sectional technique. Sampling using non-random sampling with purposive sampling technique. The sample used in this study was 83 respondents. The results of this study indicate that respondents have low knowledge of 4.82%, 72.29% of respondents are classified as moderate, and 22.89% are classified as good. Then self-medication behavior shows that 12.05% of respondents have low self-medication behavior, 62.65% of respondents are classified as moderate, and 25.30% are high. Based on the results of the Chi-Square test, insignificant results were obtained with a P value of 0.063 which indicated that there was an insignificant relationship between the level of knowledge and self-medication behavior.
Co-Authors Apriani, Laili Bayani, Faizul Lupitaningrum, Dita Marina Putri, Tursina Kamila Ramdaniah, Putri