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All Journal Journal of Food and Pharmaceutical Science Indonesian Journal of Pharmaceutical Science and Technology Jurnal Ilmu Farmasi dan Farmasi Klinik (Journal of Pharmaceutical Science and Clinical Pharmacy) MPI (Media Pharmaceutica Indonesiana) INDONESIAN JOURNAL OF PHARMACY JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA Jurnal Farmasi Sains dan Komunitas (JFSK) JURNAL ILMU KEFARMASIAN INDONESIA Jurnal Jamu Indonesia Cendekia Journal of Pharmacy MEDICINUS
Dewi Setyaningsih
Fakultas Farmasi, Universitas Sanata Dharma
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Education Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Public Health Other

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Sunscreen Cream Formulation of Noni Leaf Extract (Morinda citrifolia L.) with Emulsifier Combination of Tween 80 and Lecithin Bianca Levie Tania; Rini Dwiastuti; Agatha Budi Susiana Lestari; Dewi Setyaningsih
JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA Vol. 9 No. 3 (2022): JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jfiki.v9i32022.262-271

Abstract

Background: Noni leaf (Morinda citrifolia L.) extract is a natural product that can be used as a sunscreen. The extract contains flavonoids which function act as an antioxidant. In this work, sunscreen cream formulated with noni leaf extract was prepared using a combination of tween 80 and lecithin. Objective: The purpose of this study is to evaluate how the combination of tween 80 and lecithin affects the physical qualities of the cream, such as organoleptic, homogeneity, emulsion type, spreadability, adhesion, pH, and stability over 28 days of storage at room temperature, and to find the best formula. Methods: This study used 10% of noni leaf extract in the cream formulation. The Simplex Lattice Design (SLD) method was used to determine the effect of different concentrations of the two emulsifiers on the cream's spreadability, adhesion, and pH. Furthermore, the SLD was used to find the best formula. Results: The results showed that different concentrations of the emulsifier, which are the tween 80 and lecithin combination, affected the physical properties and storage stability of cream preparations. The interaction of tween 80 and lecithin is having a significant impact on the cream's adhesion and spreadability; however, the effect of the interaction on the pH value was not significant. Conclusion: The formula containing 2.5 % tween 80 and 2.5 percent lecithin was found to be the most effective in fulfilling the cream physical properties while remaining stable during storage.
Review: Extraction of Temulawak Rhizome (Curcuma xanthorrhiza Roxb.) and Activity As Antibacterial Lidvina Niken Yasacaxena Yasacaxena; Matea Nirmala Defi; Vicha Putri Kandari; Putri Teresa Rery Weru; Feranita Elsa Papilaya; Melania Oktafera; Dewi Setyaningsih
Jurnal Jamu Indonesia Vol. 8 No. 1 (2023): Jurnal Jamu Indonesia
Publisher : Pusat Studi Biofarmaka Tropika IPB University; Tropical Biopharmaca Research Center IPB University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/jji.v8i1.265

Abstract

Temulawak (Curcuma xanthorrhiza) is one of Indonesia’s native plants belonging to Zingiberaceae family. The plant has been extensively used for treatment of various diseases such as inflammation and digestive tract swelling, gallstones, liver, dyspepsia, and antispasmodic. The rhizome becomes the plant’s part that is used the most. The rhizome contains a compound that could work as an antibacterial. An extract of the rhizome may be obtained through extraction process, some extractions that would be used in this research review is soxhletation, maceration, and ultrasound assisted extraction (UAE). As various extraction methods both involving simple and complex ones were found, it was shown that the result of extract content are therefore varied, which was also affecting the level of resulted antibacterial effectiveness. This article was carried out to analyze the most suitable extraction method of Curcuma’s rhizome that results the highest effectiveness of antibacterial activity. The method used in this article review was a literature review on the literatures published during the period of 2012 to 2022. The highest average yield was shown on maceration method which respectively was followed by soxhletation whereas the lowest yield was resulted by UAE method
Potensi Tanaman Sukun (Artocarpus altilis) Sebagai Agen Antiinflamasi dan Antidiabetes Ni Gusti Ayu Diantari; Debby Yunita; Maria Aurelia Afila Tutonugi; Theresia Helena Tokan; Teresia Kiki Oktavianti; Florentinus Dika Octa Riswanto; Dewi Setyaningsih
MEDICINUS Vol. 36 No. 2 (2023): MEDICINUS
Publisher : PT Dexa Medica

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56951/medicinus.v36i2.122

Abstract

Background: Artocarpus altilis is a plant whose every part is beneficial for health. In Indonesia, the distribution of this plant is only found in certain places and has not been cultivated. Breadfruit is basically rich in flavonoid, tannin, and saponin compounds that are known to be potential as antidiabetic and antiinflammatory. Diabetes is a group of metabolic disease characterized by hyperglycemia, due to lack of insulin production and/or sensitivity. Type 2 diabetes is a degenerative disease that is a global health problem. Type 2 diabetes is treated using antidiabetic agents and/or insulin. Inflammation is a local reaction of the body characterized by certain symptoms. Treatment of inflammation using synthetic drugs is associated with various side effects. Objective: This review is aimed to provide information about antidiabetic and anti-inflammatory activities in breadfruit plant. Results: Substance of breadfruit plant with antidiabetic efficacy was found in the stem, leaf, and fruit, showed by results of phytochemical test. Antidiabetic activity was proven by in vivo, in vitro, and AlCl calorimetry tests, while anti-inflammatory substance was found in the leaf and fruit, and the anti-inflammatory activity was showed by results of in vivo and in vitro tests. Conclusion: Breadfruit plants can be potentially developed as an alternative treatment for diabetes and inflammation.
Co-Authors ACHMAD FUDHOLI Adelsiana Leda Adithya Guntur Agatha Budi Susiana Lestari Agatha Kania Ugahari Dyatmika Anastasia Bella Anastasia Melin Fitria Wulandari Angelina Kinsha Pandhita Arya Pratama Nugraha Pede Benedictus Wisnu Putra Jati Bianca Levie Tania Corina Febrianti Isabel Debby Yunita Debi Kristiananda Desy Natalia Rambu Padji Mahemba Enade Perdana Istyastono Ervan Setyo Nugroho Faustina Evania Ngai Feranita Elsa Papilaya Filisia Putri Rosari Florentinus Dika Octa Riswanto Giovanny Leonarda Istyastono, Enade Perdana Jeanne Magistra Noverita Juvita Lisu Allo Kevin Cahaya Putra Lidvina Niken Yasacaxena Yasacaxena Lintang Adelya Lusiana Lusiana Maria Aurelia Afila Tutonugi Mase Mase Matea Nirmala Defi Maywan Hariono Melania Oktafera Monica Selena Muhammad Radifar Ni Gusti Ayu Diantari Paulina Nadya Feranti Pebby Lorenza Pisga Chrisita Dewi Putri Teresa Rery Weru Radhita Tyastu Puteri Winengku Reynaldo Tiara Rini Dwiastuti ROCHMAT MUDJAHID Sangga Putra Dewa SUDIBYO MARTONO Teresia Kiki Oktavianti Theodora Dominika Gadi Seran Theresia Helena Tokan Titien Siwi Hartayu Triana Hertiani Veronica Arien Widyarahma Vicha Putri Kandari WOUTER L.J. HINRICHS Yohanes Krisna Wisnumurti YOSI BAYU MURTI Yosi Bayu Murti Zerlinda Clara Auw