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Aplikasi Metode Whole Chromosome Painting untuk Mendeteksi Aberasi Kromosom pada Tumor Padat Ecie Budiyanti; Des Suryani; Jeanne Adiwinata Pawitan
Majalah Patologi Indonesia Vol 23 No 1 (2014): MPI
Publisher : Perhimpunan Dokter Spesialis Patologi Indonesia (IAPI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (388.706 KB)

Abstract

In solid tumor, conventional cytogenetic method usualy fails to detect chromosomal aberation due to failure in obtaining good quality metaphases. Therefore, special technique is required to get the karyotype of solid tumors. Whole chromosome painting (WCP) is a method to paint the chromosomes using Fluorescence In Situ Hybridization (FISH) technique. Application of WCP, both using one and multiple colors (mFISH or SKY) or their modifications can be used to identify chromosomal aberrations, which are valuable in helping to attain a diagnosis, to determine the prognosis and management, and to predict the response to therapy. Key words: chromosomal aberation, FISH, solid tumor, whole chromosome painting.
Hubungan Aktivitas Fisik Dengan Nyeri Punggung Bawah Saat Pandemi Covid-19 Pada Mahasiswa fakultas Kedokteran Clara Stephanie Paul; Jimmy Fransisco Abadinta Barus; Ecie Budiyanti; Linda Suryakusuma
NEURONA Vol 39 No 1 (2021)
Publisher : PERDOSNI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52386/neurona.v39i1.315

Abstract

Introduction: COVID-19 pandemic changes lifestyle in society, one of the most obvious changes is physical activity. Physical activity has been known as one of risk factors of low back pain. Aims: To determine the relationship between physical activity and complaints of low back pain during COVID-19 pandemic among students at Faculty of Medicine and Health Science Atma Jaya Catholic University. Methods: A cross-sectional study was conducted in February until March 2021 with the studied respondents were preclinic students of Faculty of Medicine and Health Science Atma Jaya Catholic University. Data were obtained through questionnaires by online with Google Forms. Data were analyzed using Chi-Square test with significant level was set at 0,05. Results: Among 109 respondents, 52,3% medical students had moderate physical activity intensity and 27,5% had low back pain complaints. Bivariate analysis found no association between physical activity and complaints of low back pain during COVID-19 pandemic among medical students (p = 0,547). Discussion: There was no significant association between physical activity and complaints of low back pain. However, it was found that the tendency of low back pain was experienced by students who showed decrease in physical activity during the COVID-19 pandemic. Keywords: physical activity, low back pain, COVID-19 pandemic, medical student