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All Journal AGRIVITA, Journal of Agricultural Science agriTECH Jurnal Riset Industri Hasil Hutan Jurnal Kimia Mulawarman The Indonesian Biomedical Journal Jurnal Ilmiah Manuntung Journal of Tropical Pharmacy and Chemistry JURNAL ILMU KEFARMASIAN INDONESIA Jurnal Ilmiah Inovasi ULIN: Jurnal Hutan Tropis Jurnal Riset Teknologi Industri Wood Research Journal : Journal of Indonesian Wood Research Society Wood Research Journal : Journal of Indonesian Wood Research Society Bivalen: Chemical Studies Journal

Enos Tangke Arung, Enos Tangke

Faculty Of Forestry, Mulawarman University Samarinda

Author-ID : 2500357

Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Decision Sciences, Operations Research & Management Education Environmental Science Industrial & Manufacturing Engineering Materials Science & Nanotechnology Mechanical Engineering Medicine & Pharmacology Public Health Other

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Peningkatan Manfaat Buah Rotan Manau (Calamus Manan Miq.) Berdasarkan Potensi Bioaktivitas Daud Salusu, Heriad; Aryani, Farida; Budiarso, Edy; Wijaya Kusuma, Irawan; Tangke Arung, Enos
Jurnal Ilmiah Inovasi Vol 18, No 3 (2018): Jurnal Ilmiah Inovasi Vol 18 No 3
Publisher : Politeknik Negeri Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25047/jii.v18i3.1240

Rattan manau (Calamus manan Miq.) is one of the many commercial rattan species grown in the forests of East Kalimantan. The fruit can be eaten as well as the fruits of some other types of rattan, but it is also traditionally used by locals as stomach ache or toothache. Until now there has been no research that investigates the benefits of fruit for medicinal purposes or other benefits. This study aims to determine the bioactivity potential contained in the fruit of Calamus manan Miq. including phytochemical content, antioxidant properties, toxicity properties, and antibacterial activity. Parts of fruit, pericarp, flesh and seed are tested using ethanol as a solvent. The results of study showed that the pericarp and seed have higher antioxidant activity than fruit flesh where the seed have IC50 value 25,04 ppm, pericarp 41,17 ppm and fruit flesh 170,19 ppm; based on toxicity properties using BSLT (Brine Shrimp Lethality Test) test of rattan manau fruit is not toxic; while antibacterial activity against two types of bacteria showed pericarp and seeds are antibacterial activity against to Escherichia coli with strong category, while antibacterial activity against Streptococcus mutans is weak category. Keywords: antioxidant, toxicity, antibacterial, rattan, calamus.

UJI FITOKIMIA DAN ANTIOKSIDAN EKSTRAK ETANOL PROPOLIS LEBAH KELULUT (TETRAGONULA IRIDIPENNIS) DARI SAMARINDA KALIMANTAN TIMUR Khairunnisa, Binti; Rosamah, Enih; Kuspradini, Harlinda; Kusuma, Irawan Wijaya; Sukemi, Sukemi; Tandirogang, Nataniel; Arung, Enos Tangke
Jurnal Ilmiah Manuntung Vol 6 No 1 (2020): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung akademi farmasi samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (238.456 KB)

The study aims to identify the secondary metabolite compounds contained in the ethanol extract Propolis Tetragonula Iridipennis and determine the antioxidant activity. Propolis is extracted from the beehive of Kelulut (Tetragonula Iridipennis) with a method of maceration of ethanol 96% produce a yield of 66.73%. Propolis extract contains alkaloid compounds, flavonoids, triterpenoids, tannins and carbohydrates. Propolis extract tested its antioxidant activity using the DPPH method (1.1-diphenyl-2-picrylhydrazyl) with a wavelength of 514 nm. Results showed a percentage of propolis extract free radicals 59% in concentrations of 100 ppm with IC50 33.74 ppm so that propolis extract is potentially as an antioxidant.  

Aktivitas antioksidan dan antibakteri dari ekstrak bee pollen lebah kelulut (Tetragonula sarawaknensis) Sari, Ayu Mitha; Rosamah, Enih; Suwinarti, Wiwin; Kusuma, Irawan W; Arung, Ph.D., Enos Tangke
Jurnal Riset Industri Hasil Hutan Vol 13, No 2 (2021)
Publisher : Kementerian Perindustrian

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24111/jrihh.v13i2.7050

Pemanfaatan produk propolis dan bee pollen madu tanpa sengat atau Kelulut masih sangat terbatas, demikian juga penelitiannya belum banyak dilakukan bahkan bisa dikatakan masih sangat terbatas termasuk kandungan zat ekstraktif pada bee pollen tersebut. Oleh karena itu tujuan penelitian ini adalah untuk skirining manfaat bee pollen sebagai produk kecantikan dan produk yang mengandung bahan yang dapat menangkal radikal bebas. Kemajuan teknologi dan gaya hidup manusia dimasa sekarang cenderung mudah menimbulkan banyak penyakit baru. Hal ini menimbulkan rasa penasaran akan bee pollen sebagai produk dari alam yang memiliki kemampuan sebagai antioksidan dan menghambat pertumbuhan Propionibacterium acnes. Metode ekstraksi yang digunakan dalam penelitian ini adalah ekstraksi dingin etanol 98% selama 3 x 24 jam, dilanjutkan dengan uji fitokimia, dan analisis antioksidan dengan uji DPPH dan penghambatan Propionibacterium acnes dengan metode difusi agar. Ekstrak bee pollen T. sarawakensis mengandung senyawa alkaloid, flavonoid, kumarin dan tanin. Ekstrak T. sarawakensis memiliki aktivitas antioksidan dengan nilai konsentrasi hambatan 39% pada 100 mg/mL. Ekstrak memiliki penghambatan terkuat dari Propionibacterium acnes (42% pada 500 Âµg/well). Hasil ini menunjukkan adanya potensi ekstrak etanol T. sarawakensis untuk dikembangkan sebagai bahan kosmetik dan jamu, namun diperlukan percobaan lebih lanjut untuk membuktikan fungsinya.

Evaluation of Isolated Compounds from Wood of Artocarpus heterophyllus as A Cosmetic Agent Enos Tangke Arung; Kuniyoshi Shimizu; Ryuichiro Kondo
Wood Research Journal Vol 1, No 1 (2010): Wood Research Journal
Publisher : Masyarakat Peneliti Kayu Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51850/wrj.2010.1.1.40-44

In our efforts to find new whitening agent materials, we focused on wood of Artocarpus heterophyllus which is anti melanogenesis. By activity-guided fractionation of A. heterophyllus wood extract, norartocarpetin and artocarpesin were isolated which inhibited both mushroom tyrosinase activity and melanin formation in B16 melanoma cells. This compound is a strong candidate as a remedy for hyperpigmentation in human skin that can be used for cosmetic (whitening agent).

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51850/wrj.2010.1.1.40-44

POTENSI JAMUR TIRAM PUTIH (Pleurotus ostreatus) TERHADAP PENGHAMBATAN Candida albicans DAN Propionibacterium acnes Saat Egra; Irawan Wijaya Kusuma; Enos Tangke Arung
ULIN: Jurnal Hutan Tropis Vol 2, No 1 (2018)
Publisher : Fakultas Kehutanan Universitas Mulawarman

Oyster mushroom (Pleurotus ostreatus) is not a new food for the community. Long time ago oyster mushrooms is food but not so well known. Now oyster mushrooms have been accepted by the community as a healthy food. This is the background of this research to produce mushrooms not only as nutritious food but also natural medicine. The purpose of this study was to examine the antimicrobial potential of oyster mushrooms by determination of clear zone against Candida albicans and Propionibacterium acnes bacterias. This research was conducted at Forest Products Chemistry Laboratory, Faculty of Forestry, Mulawarman University. The resources of oyster mushroom we used in this study comes from the cultivation of the entrepreanure forestry student group in Mulawarman University. This study used successful extraction with hexane solvent, ethyl acetate, ethanol, water, and crude ethanol. The results obtained that the highest antimicrobial inhibition against Candida albicans bacteria with 47.60% with a concentration of 100 ppm but, on the antimicrobial against Propionibacterium acnes bacteria did not show any significant inhibition.

KANDUNGAN ANTIOKSIDAN PADA JAMUR TIRAM PUTIH (Pleurotus ostreatus) Saat Egra; Irawan Wijaya Kusuma; Enos Tangke Arung
ULIN: Jurnal Hutan Tropis Vol 2, No 2 (2018)
Publisher : Fakultas Kehutanan Universitas Mulawarman

Indonesia merupakan negara hutan tropis yang luas, maka tak heran negara ini menjadi negara megabiodiversitas. Jamur tiram merupakan salah satu hasil kekayaan alam Indonesia yang memiliki potensi sebagai tanaman kesehatan dan obat. penelitian ini bertujuan untuk memunculkan potensi aktivitas antioksidan pada jamur tiram yang banyak dibudidaya di Kalimantan Timur khususnya Samarinda. Sampel kami ambil dari rumah jamur borneo dan penelitian ini dilaksanakan di Laboratorium Kimia Hasil Hutan, Fakultas Kehutanan, Universitas Mulawarman. Metode ekstraksi bertingkat menggunakan n-heksan, etil asetat, dan etanol. Metode antioksidan yang digunakan adalah penangkal radikal bebas (DPPH) dengan masing-masing tiga kali pengulangan. Hasil penelitian ini menunjukkan bahwa aktivitas antioksidan tertinggi pada ekstrak air dengan nilai penghambatan 25% pada kosentrasi 100 ppm. Pada ekstrak heksan merupakan hambatan terkecil dengan nilai penghambatan 2,41% pada kosentrasi 25ppm.

The Toxicity and Antibacterial Properties of Calamus ornatus Bl. Rattan Fruit Heriad Daud Salusu; Ernita Obeth; Abdul Rasyid Zarta; Eva Nurmarini; Hamka Nurkaya; Irawan Wijaya Kusuma; Enos Tangke Arung
agriTECH Vol 39, No 4 (2019)
Publisher : Faculty of Agricultural Technology, Universitas Gadjah Mada, Yogyakarta, Indonesia

Calamus ornatus Bl., locally known as rotan mantang or rotan seuti is one of the commercial rattan species growing in the forests of East Borneo. Its fruit is edible, like the fruits of other species of rattan, and it has been used by the local people as traditional medicine to treat stomachache or toothache. Until recently, there has not been any study investigating the benefits of the fruit for medicinal or other purposes. This research aimed to discover the bio-activity potentials of Calamus ornatus Bl. fruits by identifying its toxicity level and antibacterial potentials. The parts of the fruit (pericarp, flesh, and seed) were extracted using ethanol as solvent to extract samples. The toxicity was analyzed by using the Brine Shrimp Lethality Test (BSLT) method while the antibacterial activity was tested using a well diffusion method. Low toxicity was found in the flesh, whereas the pericarp and the seed were non-toxic. Antibacterial activity against Escherichia coli was found in the pericarp and the seed, while antibacterial activity against Streptococcus mutans was found in the pericarp and the flesh.

UJI BIOAKTIVITAS PADA EKSTRAK KASAR ETANOL, FRAKSI n-HEKSAN, ETIL ASETAT DAN ETANOL-AIR DARI DAUN ANDONG (Cordyline terminalis Kunth) Ritson Purba; Enos Tangke Arung; Teddy Tranoto
JURNAL KIMIA MULAWARMAN Vol 11 No 2 (2014)
Publisher : Jurusan Kimia Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Mulawarman

Show Abstract | Download Original | Original Source | Check in Google Scholar

Phytochemical, brine shrimp lethality and antibacterial activity tests in each fraction from Andong leaves extract(Cordyline terminalis Kunth) that came fromUnmul Samarinda botanical garden, Kalimantan Timur has been carried out. The leaf was extracted with ethanol andconcentrated by using rotaryevaporator. The crudeethanol extract was fractioned with n-hexane, and ethyl acetate. Based on the secondary metabolites phytochemical test of the Cordyline terminalis Kunth leaves show that crudeethanol extract is contain phenol, saponin and steroid.n-hexane fraction iscontain steroid.Ethylacetate fraction is contain phenol and steroid. And ethanol-water fraction is contain phenol and saponin. Brine shrimp lethality test exhibit mortality rate of Artemiasalina (L) by Probit SAS analysis to determine lethal concentration 50% (LC 50 ) value. The test showed that the most active wascrudeethanol extract with LC 50 value of 26.8788 ppm. Antibacteria activity test of extracts for Bacillus cereus bacteria (positiveGram) andEscherichia coli (negativeGram) were carried out by paper disk method. The test showed that the most active were ethyl acetate extract with minimum inhibitor consentration of 2-10% which clear zone diameter was 6,4 mm on Bacillus cereus bacteria and 6 mm on Escherichia colibacteria.Keywords: Phytochemical, Antibacteria activity, LC 50

Brucea javanica Leaf Extract Induced Apoptosis in Human Oral Squamous Cell Carcinoma (HSC2) Cells by Attenuation of Mitochondrial Membrane Permeability Britanto Dani Wicaksono; Enos Tangkearung; Ferry Sandra
The Indonesian Biomedical Journal Vol 7, No 2 (2015)
Publisher : The Prodia Education and Research Institute (PERI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18585/inabj.v7i2.76

BACKGROUND: Brucea javanica extract has been reported to have anti-proliferative and cell death induction activities. B. javanica extract was reported to induce apoptosis through caspase cascade. Most of investigated B. javanica extracts were derived from seeds and fruits, or commercially available oil emulsion. Therefore we conducted a study on B. javanica leaf extract (BJLE) in oral cancer cells.METHODS: B. javanica leaves were collected, identified, minced, dried, extracted with distilled ethanol at room temperature for 24 hours, filtered and evaporated. Resulted BJLE was stored at 4°C. Human oral squamous cell carcinoma (HSC)-2 cells were fasted for 12 hours and treated with BJLE in various concentrations for 24 hours. Cells were then quantified with 3-(4,5-dimethylthiazol-2-yl)-2,5-Diphenyltetrazolium bromide (MTT) assay, demonstrated with 4',6'-diamidino-2-phenylindole (DAPI) staining. To find out mitochondrial membrane permeability (MMP), mitochondrial membrane potential (ΔΨM) was analyzed.RESULTS: BJLE reduced percentage of viable HSC-2 cells in a concentration dependent manner. BJLE induced apoptosis in HSC-2 cells. With treatment of 50 μg/ml BJLE, fragmented nuclei were seen. ΔΨM of HSC-2 cells treated with 50 μg/ml BJLE were shifted to the left, meaning that BJLE induced reduction of ΔΨM and attenuation of MMP.CONCLUSION: Our results suggested that BJLE could induce apoptosis by attenuating MMP.KEYWORDS: Brucea javanica, leaf, apoptosis, HSC-2, MTT, DAPI, mitochondria, permeability

Co-Authors A.A. Ketut Agung Cahyawan W Abdul Rasyid Zarta Abdul Rasyid Zarta Amalia Riska Setyani Bayu Susetya Ananda Britanto Dani Wicaksono Dyah Ayu Dewi Listyaningrum Edy Budiarso Edy Budiarso Edy Budiarso Enih Rosamah Ernita Obeth Ernita Obeth Eva Nurmarini Farida Ariani Farida Aryani Ferry Sandra Hamka Nurkaya Heriad Daud Salusu Heriad Daud Salusu Heriad Daud Salusu Irawan Wijaya Kusuma, Irawan Wijaya Khairunnisa, Binti Kuniyoshi Shimizu KUNIYOSHI SHIMIZU Kusuma, Irawan W Mark Rayment Nataniel Tandirogang Nor Hikmah Rico Ramadhan Ritson Purba Ritson Purba, Ritson Rosamah, Enih Rosamah, Enih Rudianto Amirta Ryuichiro Kondo Saat Egra Sarah Azzara Dikarulin Sari, Ayu Mitha Sukemi Sukemi Suwinarti, Wiwin Tasya Ananda Putri Teddy Tranoto Teddy Tranoto, Teddy Wijaya Kusuma, Irawan Wiwin Suwinarti Yanti Puspita Sari Yuliansyah Yuliansyah Yundari, Yundari

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