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Journal : Wood Research Journal : Journal of Indonesian Wood Research Society

Evaluation of Isolated Compounds from Wood of Artocarpus heterophyllus as A Cosmetic Agent Enos Tangke Arung; Kuniyoshi Shimizu; Ryuichiro Kondo
Wood Research Journal Vol 1, No 1 (2010): Wood Research Journal
Publisher : Masyarakat Peneliti Kayu Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51850/wrj.2010.1.1.40-44

Abstract

In our efforts to find new whitening agent materials, we focused on wood of Artocarpus heterophyllus which is anti melanogenesis. By activity-guided fractionation of A. heterophyllus wood extract, norartocarpetin and artocarpesin were isolated which inhibited both mushroom tyrosinase activity and melanin formation in B16 melanoma cells. This compound is a strong candidate as a remedy for hyperpigmentation in human skin that can be used for cosmetic (whitening agent).