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All Journal Jurnal Anestesiologi Indonesia Health Notions Jurnal Medik Veteriner Indonesian Journal of Clinical Pathology and Medical Laboratory (IJCPML) Civilla : Jurnal Teknik Sipil Universitas Islam Lamongan
Edward Kusuma
Department Of Anesthesiology And Reanimation, Faculty Of Medicine, Universitas Airlangga/Dr. Soetomo General Academic Hospital, Surabaya
Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Medicine & Pharmacology Neuroscience Nursing Public Health Veterinary

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Correlation Between Sepsis Bundle Compliance with Incidence of Acute Kidney Injury and Mortality in Sepsis Adult Patients Eka Prasetiyawan; Arie Utariani; Edward Kusuma
Health Notions Vol 4, No 2 (2020): February
Publisher : Humanistic Network for Science and Technology (HNST)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33846/hn40205

Abstract

Sepsis is serious medical condition with mortality rate around 25%. Sepsis cause multiorgan failure, including AKI (Acute Kidney Injury). One-hour sepsis bundle compliance is expected to prevent AKI and reduce patient mortality. Aims: Analyze the correlation between sepsis bundle compliance with incidence and progression of AKI and mortality in first 48 hours of treatment in the Resuscitation Room (Intensive) of RSUD Dr. Soetomo Surabaya. Methods: Observational retrospective study. Total sampling from medical record of adult sepsis patients who treated in Resuscitation/ Intensive Room of RSUD Dr. Soetomo in January - July 2019. Sepsis bundle compliance was assessed in first 1-hour patient was treated, then observed in first 48 hours of treatment, whether there was death or AKI. Results: Most of the 1-hour survival bundle sepsis compliance were classified as poor (51.6%) and very poor (26.9%). The highest component was antibiotic administration management (63.4%) and the lowest was fluid resuscitation (8.6%). There is significant correlation between sepsis bundle compliance with AKI incidence in the first 6 hours, p value= 0.048; contingency coefficient 0.280. Cumulatively, there is significant correlation between sepsis bundle compliance with mortality rates sepsis patients under 48 hours, p value: 0.000; contingency coefficient 0.614. There is significant correlation between bundle sepsis compliance to mortality under 6; 12; 42; and 48 hours. Conclusions: There is significant correlation between sepsis bundles compliance with AKI incidence in first 6 hours. There is significant correlation between sepsis bundle compliance to the mortality rate of sepsis patients under 48 hours of treatment. Keywords: compliance; one-hour sepsis bundle; AKI; mortality
Study of Progress Expected Results Based on Percentage of Construction Work Plan Duration Mardiaman Mardiaman; Edward Kusuma
Civilla : Jurnal Teknik Sipil Universitas Islam Lamongan Vol 6, No 2 (2021): September
Publisher : Litbang Pemas - Universitas Islam Lamongan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30736/cvl.v6i2.628

Abstract

Abstract. Controlling how construction work is completed is critical to success. Generally, the result value method is used as the tool. Although this method has been applied to a variety of different types of construction work, the tool has been limited to a single project. This study examines the total value of completed construction work. Because the duration of construction work varies, the researchers refer to the percentage of the plan's duration. The percentages are set at 25%, 30%, and 50%. There have been 17 completed building construction projects between 2017 and 2018. Additionally, a comparison sample of construction work is used. The results of the data processing are pessimistic, most likely, optimistic, and hopeful. Additionally, the expected value is compared to a reference value. The expected values for the percentages of 25%, 30%, and 50% are (-2.425), (1.071), and 50%, respectively (2.275). Indeed, the expected value obtained is not the same as the comparison value. The contractor can prepare the necessary resources by knowing the value of the expected yield at a certain percentage of the duration. 
Perbandingan Efektivitas Antara Nebulisasi Lidokain dan Spray Lidokain untuk Mencegah Refleks Batuk pada Tindakan Bronkoskopi dengan General Anestesi Anna Erliana Oetarman; Edward Kusuma; Maulydia Maulydia; Arie Utariani
JAI (Jurnal Anestesiologi Indonesia) Vol 12, No 2 (2020): Jurnal Anestesiologi Indonesia
Publisher : Perhimpunan Dokter Spesialis Anestesiologi dan Terapi Intensif

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jai.v12i2.29418

Abstract

Latar belakang: Batuk sering terjadi pada tindakan bronkoskopi. Batuk menyebabkan ketidaknyamanan pasien dan menimbulkan kesulitan pada pelaksanaan tindakan bronkoskopi sehingga dapat meningkatkan risiko komplikasi akibat bronkoskopi seperti perdarahan intrabronkial, bronchospasme, dan pneumothorax. Batuk pada tindakan bronkoskopi dapat dicegah dengan pemberian anestesi lokal lidokain.Tujuan: Membandingkan efek nebulisasi lidokain 2 % dibandingkan spray lidokain 10% dalam mencegah kejadian batuk pada tindakan bronkoskopi dengan anestesi umum.Metode: Penelitian dilakukan pada 20 pasien usia 18-65 tahun dengan status fisik American Society of Anesthesiologist (ASA) I dan II yang menjalani tindakan bronkoskopi dengan anestesi umum menggunakan intubasi oral. Pasien dibagi 2 kelompok: kelompok spray lidokain 10% dan kelompok nebulisasi lidokain 2% dengan dosis lidokain yang sama yaitu 2 mg/kgbb. Tanda vital (tekanan darah, laju jantung, saturasi oksigen serta frekuensi napas) dan kedalaman anestesi dengan bispectral index (BIS) diukur selama bronkoskopi. Spray lidokain dan nebulisasi lidokain diberikan sebelum pembiusan dilakukan. Kemudian dievaluasi kejadian batuk dan derajat batuk selama dan setelah tindakan bronkoskopi. Analisis hasil penelitian menggunakan dua metode yaitu uji Mann Whitney dan uji Wilcoxon. Uji Mann Whitney dengan derajat kemaknaan p<0,05 untuk membandingkan kejadian batuk pada kedua kelompok selama dan dua jam setelah bronkoskopi, sedangkan uji Wilcoxon dengan derajat kemaknaan p<0,05 untuk membandingkan derajat batuk sebelum bronkoskopi dan selama bronkoskopi pada masing kelompok.Hasil: Terdapat perbedaan bermakna derajat batuk antara sebelum dan sesudah pemberian spray lidokain maupun nebulisasi lidokain (p<0,05). Ada perbedaan bermakna derajat batuk antara kelompok spray lidokain dibandingkan nebulisasi lidokain (p<0,05), dimana nebulisasi lidokain menimbulkan derajat batuk lebih rendah dibandingkan spray lidokain. Tidak ada efek samping pada penelitian ini.Kesimpulan: Pemberian nebulisasi lidokain 2% lebih efektif menekan refleks batuk dibandingkan spray lidokain 10% pada tindakan bronkoskopi dengan general anestesi.
Cut-Off Value of Procalcitonin in Sepsis and Septic Shock patients at Dr. Soetomo Hospital Shinta Lungit Ambaringrum; Yetti Hernaningsih; Edward Kusuma; Hartono Kahar
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol 28, No 2 (2022)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v28i2.1827

Abstract

Sepsis is a state of life-threatening organ dysfunction caused by dysregulation of the body's response to infection. Organ dysfunction is marked by an increase in SOFA score ≥ 2 or qSOFA score ≥ 2. Septic shock is a subset of sepsis with fairly severe circulatory disorders that can significantly increase mortality. Although the current gold standard diagnosis method for sepsis is bacterial culture, some researchers believe PCT can help identify sepsis severity because bacterial culture requires a relatively long time. This study aims to determine the cut-off point of procalcitonin in patients with sepsis and septic shock. The data taken were secondary data from the medical records of sepsis and septic shock patients in Dr. Soetomo General Hospital from 2017 to 2019. Determination of cut-off PCT for sepsis and septic shock using Receiver Operating Characteristic (ROC) analysis curve. Most sepsis patients were young (18 - 65 years) (69%) (p = 0.331) and male (60%) (p = 0.156). The majority of the clinical sepsis patients have focal infections of the respiratory system (55.17%). Patients with respiratory tract infections who develop sepsis have an OR of 6.182, which means it is six times more likely to develop septic shock. There was a significant difference between septic and non-septic PCT levels (p = 0.000), and there was a positive correlation between PCT and sepsis. The cut-off of procalcitonin in sepsis was 0.6 ng/mL, and the cut-off of procalcitonin in septic shock was 10 ng/mL.
Efek Analgesik Ekstrak Etanol Zingiber cassumunar Roxb. pada Mencit dengan Metode Writhing Test Qonita Bajuber; Danti Nur Indiastuti; Edward Kusuma
Jurnal Medik Veteriner Vol. 3 No. 1 (2020): April
Publisher : Faculty of Veterinary Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (437.601 KB) | DOI: 10.20473/jmv.vol3.iss1.2020.45-50

Abstract

Penelitian bertujuan untuk menguji efek analgesik ekstrak etanol Zingiber cassumunar Roxb. pada mencit yang diinduksi dengan asam asetat. Penelitian ini merupakan penelitian eksperiment  posttest only control design, menggunakan metode writhing test. Sampel penelitian terdiri dari 25 mencit terbagi dalam tiga kelompok perlakuan ekstrak Zingiber cassumunar Roxb.; P1, P2, dan P3, dengan masing-masing dosis 100 mg/kgBB, 200 mg/kgBB, 400 mg/kgBB, kelompok kontrol negatif aquades (K-), serta kelompok kontrol positif aspirin (K+). Hasil penelitian menunjukkan bahwa (P1) dan (P2) signifikan menurunkan jumlah geliat pada mencit dibandingkan (K-) (p < 0,05), dengan persentase penurunan jumlah geliat sebesar 49,53% dan 57,01%, sedangkan (P3) tidak menunjukkan aktivitas analgesik. Ekstrak Zingiber cassumunar Roxb. dosis 100 mg/kgBB dan 200 mg/kgBB tidak memiliki perbedaan yang signifikan terhadap (K+) untuk mengurangi rasa nyeri.
Cut-Off Value of Procalcitonin in Sepsis and Septic Shock patients at Dr. Soetomo Hospital Shinta Lungit Ambaringrum; Yetti Hernaningsih; Edward Kusuma; Hartono Kahar
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol. 28 No. 2 (2022)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v28i2.1827

Abstract

Sepsis is a state of life-threatening organ dysfunction caused by dysregulation of the body's response to infection. Organ dysfunction is marked by an increase in SOFA score ≥ 2 or qSOFA score ≥ 2. Septic shock is a subset of sepsis with fairly severe circulatory disorders that can significantly increase mortality. Although the current gold standard diagnosis method for sepsis is bacterial culture, some researchers believe PCT can help identify sepsis severity because bacterial culture requires a relatively long time. This study aims to determine the cut-off point of procalcitonin in patients with sepsis and septic shock. The data taken were secondary data from the medical records of sepsis and septic shock patients in Dr. Soetomo General Hospital from 2017 to 2019. Determination of cut-off PCT for sepsis and septic shock using Receiver Operating Characteristic (ROC) analysis curve. Most sepsis patients were young (18 - 65 years) (69%) (p = 0.331) and male (60%) (p = 0.156). The majority of the clinical sepsis patients have focal infections of the respiratory system (55.17%). Patients with respiratory tract infections who develop sepsis have an OR of 6.182, which means it is six times more likely to develop septic shock. There was a significant difference between septic and non-septic PCT levels (p = 0.000), and there was a positive correlation between PCT and sepsis. The cut-off of procalcitonin in sepsis was 0.6 ng/mL, and the cut-off of procalcitonin in septic shock was 10 ng/mL.
Co-Authors Anna Erliana Oetarman Danti Nur Indiastuti Eka Prasetiyawan Hartono Kahar, Hartono Mardiaman Mardiaman Maulydia, Maulydia Qonita Bajuber Shinta Lungit Ambaringrum Utariani, Arie Yetti Hernaningsih