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Factors associated with the need for intraoperative packed red cells transfusion in pediatric liver transplant patients Kapuangan, Christopher; Utariani, Arie; Hanindito, Elizeus
Bali Journal of Anesthesiology Vol 3, No 1 (2019)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (201.652 KB) | DOI: 10.15562/bjoa.v3i1.143

Abstract

Background: Massive hemorrhage is one of the most common problems encountered during a liver transplantation procedure. Correction of the blood loss using packed red cells (PRC) is essential during the procedure to improve outcome. This retrospective study aims to investigate preoperative and intraoperative factors that may predict the PRC need.Materials and Methods: Thirty-four patients who underwent pediatric liver transplantation procedure within 2010-2018 were included in this study. Their medical record was examined and the data was analyzed using a comparison of mean and regression model.Results: The mean bleeding in this study was found to be 906.62±674.30 mL, while the mean PRC transfusion was 566.71±307.30 mL. Correction of blood loss was also compensated with other means such as a crystalloid or colloid fluid.Conclusion: This study statistically demonstrated that pre-operative weight, as well as bleeding volume, significantly affect the PRC transfusion requirement (p <0.05). However, other factors such as hemoglobin and surgical duration may also be clinically significant factors to predict PRC transfusion need.
The ultrasonic cardiac output monitor (USCOM) as a tool in evaluating fluid responsiveness in pediatric patients underwent emergency surgery Kurniyanta, Putu; Utariani, Arie; Hanindito, Elizeus; Ryalino, Christopher
Bali Journal of Anesthesiology Vol 3, No 1 (2019)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (192.302 KB) | DOI: 10.15562/bjoa.v3i1.111

Abstract

ABSTRACTBackground: Assessment fluid adequacy in pediatric patients underwent surgery is a challenge for anesthesiologists. Hemodynamic parameters used as fluid monitoring sometimes don’t accurately provide valid information. Ultrasonic Cardiac Output Monitor (USCOM) is one of the non-invasive methods that are easy to operate and may provide various hemodynamic parameters monitoring information.Objective: Analyze the effectiveness of Stroke Volume Variation (SVV) and Stroke Volume Index (SVI) by using USCOM in assessing fluid responsiveness in preoperative pediatric patients who underwent emergency surgeries.        Method: This study was conducted on 16 pediatric patients underwent emergency surgeries. Before general anesthesia is given, blood pressure, mean arterial pressure, heart rate, cardiac index, SVV, SVI were recorded before and after administration of 10 mL/kg of fluid given within 20 minutes.Results: 10 subjects responded with SVV and SVI changes of more than 10% compared to 6 non-responders. SVV changes between responders and non-responders were 31.5±1.58 and 7.5±1.04, respectively. SVV percentage changes between responders and non-responders were 38.04±0.47 and 5.24±4.89, respectively.Conclusion: SVV and SVI recorded by USCOM showed significant fluid responsiveness changes in pediatric patients underwent emergency surgeries in 62.5% of the subjects.
Laporan Kasus : PERAWATAN GAGAL NAPAS AKUT AKIBAT PNEUMONITIS LUPUS DI UNIT PERAWATAN INTENSIF DENGAN FASILITAS TERBATAS Hanif, Hanif; Semedi, Bambang Pujo; Utariani, Arie
Majalah Kesehatan FKUB Vol 7, No 1 (2020): Majalah Kesehatan
Publisher : Faculty of Medicine Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (797.088 KB) | DOI: 10.21776/ub.majalahkesehatan.2020.007.01.6

Abstract

Pneumonitis lupus, salah satu manifestasi klinis SLE, dapat mengalami perburukan hingga menjadi gagal napas. Penanganan yang tepat diperlukan, meskipun dengan fasilitas terbatas. Mendiskusikan pengalaman klinis dalam menangani pasien dengan gagal napas akut di unit perawatan intensif (ICU) dengan keterbatasan fasilitas. Wanita 23 tahun dirawat di ICU dengan gagal napas akut yang dicurigai akibat pneumonitis lupus. Pemeriksaan laboratorium untuk mengkonfirmasi diagnosis tidak tersedia. Keputusan untuk mempertahankan pasien dengan bantuan ventilator atau ekstubasi dibuat berdasarkan parameter klinis saja. Pada awalnya, kemajuan terapi cukup menjanjikan. Pasien dapat bernapas spontan untuk beberapa hari, sebelum kemudian perlu di intubasi ulang akibat flare lupus kedua. Kondisi klinis pasien memburuk dengan cepat dan akhirnya pasien meninggal.  Meskiput banyak keterbatasan di ICU, penilaian klinis dan evaluasi ketat sangat diperlukan sebagai dasar pengambilan keputusan penting seperti kapan harus memulai dan menghentikan bantuan ventilator.
The Relationship Between Qor-40 Questionary Value And Pupillary Pain Index As Assessment Of Recovery Quality On Post-Operating Patients Treated By Multimodal Analgesia (Parasetamol + NSAID + PCA OPIOID) Wayan Dhea Agastya1 , Arie Utariani2 , Dedi Susila2
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 3 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i3.10763

Abstract

This study analyzes the correlation between QoR-40 questionnaire value and the Pupillary Pain Index as an assessment for the quality of recovery of postoperative patients receiving multimodal analgesia (Paracetamol + NSAID + PCA Opioid) in Dr. Soetomo Hospital. An observational analytic study with cross-sectional design was conducted on patients aged 18-60 years who underwent elective surgery with general anesthesia at Dr. Soetomo Hospital Surabaya and receiving multimodal analgesia therapy, which includes intravenous paracetamol 4 x 500 mg, intravenous ketorolac 3 x 10 mg, and intravenous fentanyl via PCA. Recovery quality checks were performed at 12 and 24 hours postoperatively. Retrieval of data in the form of a QoR-40 questionnaire and pupillary pain index examination using algiscan® pupillometry. Both parameters will be analyzed by correlation test. The total need for fentanyl and PCA demand dose was also evaluated for use within 24 hours postoperatively. From 46 samples, obtained characteristics of studyare widely distributed in terms of age, sex, anthropometry, and preoperative physical status. The average total fentanyl PCA requirement is relatively small at 0.28 mcg / kg / hour. The correlation formed between QoR- 40 and pupillary pain index is significant. It can be concluded that Pupillary Pain Index can replace the QoR-40 questionnaire as an alternative assessment of the quality of recovery of patients after surgery
prediksi berat badan pasien pediatri : analisis akurasi mercy method di rsud dr soetomo surabaya Khildan Miftahul Firdaus; Arie Utariani
Jurnal Anestesi Perioperatif Vol 8, No 3 (2020)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15851/jap.v8n3.2098

Abstract

Resusitasi pediatri bergantung pada berat badan untuk menentukan ukuran alat resusitasi, dosis obat, jumlah cairan, hingga dosis defibrilasi yang dibutuhkan. Berat badan aktual pada kondisi kegawatan sering kali sulit diukur sehingga membutuhkan suatu metode prediksi. Mercy method merupakan salah satu modalitas prediksi berat badan berbasis panjang yang dapat digunakan. Tujuan, menganalisis akurasi Mercy method sebagai metode prediksi berat badan pasien pediatri. Metode, dalam penelitian analitik observasional ini dilakukan pengukuran berat badan, panjang lengan, dan lingkar lengan atas tengah pada pasien usia 2 bulan–16 tahun di IRNA Pediatri RSUD Dr. Soetomo periode Desember 2019 hingga Maret 2020. Panjang dan lingkar lengan atas tengah kemudian dikonversi menjadi berat badan prediksi menggunakan Mercy method, lalu dilakukan uji korelasi dengan berat badan aktual. Uji bias dan predictive performance dinilai menggunakan ME, MAPE, RMSE, dan toleransi berat badan hingga 10% dan 20%. Hasil, dari 375 pasien, didapatkan hasil bahwa Mercy method merupakan modalitas yang baik untuk memprediksi berat badan pediatri pada populasi ini (r2=.964; p,000). Hasil uji bias dan predictive performance juga menunjukkan hasil yang baik dengan ME yang rendah, MAPE <10%, RMSE mendekati nol, serta dapat memprediksi berat badan aktual dengan toleransi 20% hingga 97,4%. Simpulan, Mercy method merupakan metode yang akurat untuk memprediksi berat badan pasien pediatri di RSUD Dr. Soetomo Surabaya. Feasibility Analysis of the Mercy Method - Weight Estimation Pediatric PatientsMost pediatric resuscitations interventions are based on the patient's body weight to determine the resuscitation device’s size, drug dose, amount of fluid needed, and defibrillation joule. Measurement of actual body weight in the emergency setting is often impossible because it requires a weight estimation method. The Mercy method is one of the modalities of length-based weight estimation used in emergency departments. This study aimed to analyze Mercy method’s accuracy as a weight estimation method in pediatric patients at RSUD Dr. Soetomo Surabaya in December 2019–March 2020. This prospective,  observational analytic, single-center study, measured the actual body weight (ABW), humeral length (HL) and mid- arm circumference (MAC) of patients aged 2 months–16 years at the pediatric ward with consecutive sampling techniques. HL and MAC were converted to predictive body weight (PBW) based on Mercy method. Then, PBWs were regressed against ABWs. The predictive performance assessment used mean error (ME), mean absolute percentage error (MAPE), root mean square error (RMSE) and the predicted percentage was within 10% and 20% (Agreement 10% and 20%). Results from 375 pediatric patients showed that the Mercy method offered a good correlation between ABW and PBW (r2=.964, p.000); Mercy method also demonstrated good predictive performance results with low ME, MAPE <10% and RMSE close to zero. The Mercy method estimated weight within 20% of ABW for nearly all children (97.4%) in this study population. In conclusion, the Mercy method performed exceptionally well in this study population without modification, extending this weight estimation strategy.
Penggunaan Ventilatory Ratio dan Dead Space Fraction Sebagai Prediktor Mortalitas Pada Pasien COVID-19 dengan Acute Respiratory Distress Syndrome Muh Kemal Putra; Arie Utariani; Bambang Pujo Semedi; Christrijogo Soemartono Waloejo; Hardiono Hardiono
Jurnal Anestesi Perioperatif Vol 9, No 1 (2021)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15851/jap.v9n1.2274

Abstract

Pada pasien COVID-19 dengan ARDS terjadi gangguan oksigenasi dan ventilasi. Menurut kriteria Berlin ARDS, oksigenasi diukur dengan PaO2/FiO2, namun tidak mengukur ventilasi alveolar yang diukur dengan dead space yang dapat terjadi akibat kondisi, seperti kerusakan endotel, mikrotrombus, dan penggunaan ventilator yang berlebih. Tujuan penelitian ini menganalisis penggunaan ventilatory ratio (VR) dan dead space fraction (Vd/Vt) sebagai prediktor mortalitas pasien COVID-19 ARDS. Penelitian ini adalah analitik kohort retrospektif. Data dikumpulkan dari rekam medik pasien COVID-19 yang dirawat di RIK RSUD Dr. Soetomo periode Juni–September 2020 dengan teknik total sampling terhadap subjek yang memenuhi kriteria inklusi dan tidak termasuk eksklusi. Data yang dikumpulkan adalah nilai VR dan Vd/Vt (diambil dari data laboratorium), kondisi klinis pasien dan pengaturan ventilator 24 jam pertama setelah terintubasi. Penelitian ini didapatkan 77 dari 80 subjek yang memenuhi kriteria. Nilai VR berhubungan dengan mortalitas secara signifikan dengan nilai p 0,001; cut off 1,84; sensitivitas 84,2%; spesifisitas 85%; RR 30,22; CI 95%: 7,31–124,89. Vd/Vt dan mortalitas menunjukkan hubungan yang signifikan terhadap mortalitas dengan nilai p 0.001. Uji analisis Spearman VR dengan Vd/Vt didapatkan hasil korelasi yang kuat dengan koefisien korelasi 0,704 dan p 0,001. Simpulan, nilai VR dan Vd/Vt dapat digunakan sebagai prediktor mortalitas pasien COVID-19 dengan ARDS dan keduanya mempunyai korelasi yang kuat. VR dapat menggantikan Vd/Vt.Use of Ventilatory Ratio and Alveolar Dead Space Fraction as Predictorz of Mortality in Covid-19 Patients with Acute Respiratory Distress SyndromeCOVID-19 with ARDS experience impaired oxygenation and ventilation. In Berlin ARDS criteria, oxygenation is measured by PaO2 /FiO2, but does not measure alveolar ventilation, which is measured through the dead space produced in this conditions, such as endothelial damage, microthrombus, and excessive use of entilator. The purpose of this study was to analyze the use of ventilatory ratio (VR) and dead space fraction (Vd/Vt) as predictors of mortality in patients with COVID-19 ARDS. This study was a retrospective cohort analytic study one medical records of COVID-19 patients treated in an inpatient unit of a referral hospital in Indonesia. The ethical clearance was obtained from the Health Research Ethics Committee of Dr. Soetomo Hospital, Indonesia. Data were collected through total sampling of medical records that met the inclusion and exclusion criteria. The VR and Vd/Vt scores were collected from the laboratory data, patient clinical condition, and ventilator setting 24 hours after intubation. Of all medical records screened, 77 out of 80 samples met the criteria. VR was significantly associated with mortality with a p value of 0.001 (cut-off point:1.84, sensitivity: 84.2%, specificity: 85%, RR: 30.22, and 95%, CI: 7.31–124.89). Similarly, Vd/Vt and mortality showed a significant relationship with mortality with a p value of 0.001 (cut-off: 0.25, sensitivity: 85%, specificity: 86%, RR: 34.71, 95% CI: 8.24–146.05). The Spearman analysis test between VR and Vd/Vt showed a strong correlation with a correlation coefficient of 0,704 and p 0,001. Thus, VR and Vd/Vt can be used as predictors of mortality in COVID-19 patients with ARDS and because both have a strong correlation. VR can also substitute Vd/Vt.
Analisis Faktor Risiko Oxygenation Index, Oxygen Saturation Index, dan Rasio Pao2/Fio2 sebagai Prediktor Mortalitas Pasien Pneumonia COVID-19 dengan ARDS di Ruang Perawatan Intensif Isolasi Khusus RSUD Dr Soetomo Samuel Hananiel Rory; Arie Utariani; Bambang Pujo Semedi
Jurnal Anestesi Perioperatif Vol 9, No 1 (2021)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15851/jap.v9n1.2275

Abstract

Pada kasus berat, pneumonia COVID-19 terjadi perburukan secara cepat dan progresif yang menyebabkan ARDS. Pengukuran parameter oksigenasi seperti oxygenation index (OI) dan oxygen saturation index (OSI) pada beberapa penelitian menunjukkan superioritas dibanding dengan rasio PaO2/FiO2 dalam menilai status oksigenasi dan derajat keparahan ARDS. Penelitian ini bertujuan melakukan analisis faktor risiko OI, OSI, dan Rasio PaO2/FiO2 terhadap mortalitas pasien pneumonia COVID-19 dengan ARDS. Penelitian ini adalah penelitian analitik observaional dengan desain cohort-prospective terhadap pasien dewasa pneumonia COVID-19 dengan ARDS berdasar atas kriteria Berlin. Data perhitungan OI, OSI, dan rasio PaO2/FiO2 diambil pada 30 menit pertama pascapemasangan ventilator mekanik. Analisis regresi logistik digunakan untuk menganalisis faktor risiko OI, OSI, dan rasio PaO2/FiO2 terhadap mortalitas 28 hari pasien pneumonia COVID-19 dengan ARDS. Hasil penelitian didapatkan pada 77 pasien yang memenuhi kriteria inklusi dan tidak termasuk eksklusi, hanya variabel OI yang terbukti signifikan sebagai prediktor independen mortalitas dengan nilai p 0,043, sementara OSI dan rasio PaO2/FiO2 tidak signifikan. Dari ketiga variabel, OI mempunyai AUC tertinggi, yakni 0,935 dibanding dengan variabel OSI dan rasio PaO2/FiO2. Simpulan, OI terbukti sebagai prediktor independen mortalitas pada pasien pneumonia COVID-19 dengan ARDS.Oxygen Index, Oxygenation Saturation Index, and Pao2/Fio2 Ratio as Predictors of Mortality in Pneumonia Covid-19 with ARDS Patients Treated in Intensive Isolated Care Unit In severe COVID-19 cases, worsening of pneumonia occurs rapidly and leads to ARDS. Oxygenation parameters such as oxygenation index (OI) and oxygen saturation index (OSI) has been shown to be superior when compared to the PaO2/FiO2 ratio in assessing the oxygenation status and ARDS severity in some studies. Currently, there are limited studies that explore the prognostic values of these parameters in pneumonia COVID-19 with ARDS. This study aimed to analyze the OI, OSI, and PaO2/FiO2 Ratio as predictors of mortality in pneumonia COVID-19 with ARDS in patients treated in the intensive isolated care room. This was an observational analytic study conducted at dr. Soetomo Hospital, Indonesia, on adult patients who met the criteria for pneumonia COVID-19 with ARDS based on Berlin criteria. Data on OI, OSI, and PaO2/FiO2 were collected based on the results of measurements 30 minutes post-intubation and mechanical ventilation in these patients. Logistic regression analysis was used to analyze the OI, OSI, and PaO2/FiO2 as risk factors for 28 days mortality of pneumonia COVID-19 patients with ARDS. In a total of 77 patients eligible for the analyses, it was observed that OI was independently associated with hospital mortality (p 0.043) while OSI and PaO2/FiO2 ratio were not statistically significant. From these three variables, the AUC for mortality prediction was the greatest for OI (AUC 0.935, p<0.05). In conclusion, OI is the only one that is proven to be the independent predictor mortality with the highest sensitivity and specificity compared to the OSI and PaO2/FiO2 ratio for patients with pneumonia covid-19 with ARDS.
Comparison General Anesthesia And Combined Scalp Block With Ropivacaine 0.5% On Mean Arterial Pressure, Heartrate And Fentanyl Consumption During Craniotomy. Rudi Iskandar Suryadani; Hamzah Hamzah; Nancy Margarita Rehatta; Arie Utariani
JURNAL WIDYA MEDIKA Vol 6, No 1 (2020): April
Publisher : FAKULTAS KEDOKTERAN UNIVERSITAS KATOLIK WIDYA MANDALA SURABAYA

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (752.456 KB) | DOI: 10.33508/jwm.v6i1.2499

Abstract

Surgical craniotomy such as skin incisions, head pinning, periosteal-dural contact, dura closure, bones and skin can cause of nociceptive stimulation. These actions are stimuli to the nerves that can stimulate stress response. The stress response to surgery is characterized by increased secretion of the pituitary hormone and activation of the sympathetic nervous system. Hypothalamic activation of the sympathetic autonomic nervous system results in increased secretion of catecholamines from the adrenal medulla and the release of norepinephrine from the presynaptic nerve terminal. Objectives: This study is a single blind experimental, 14 patients with ages 18-60 years physical status ASA (American Society of Anesthesiologists) 1-3, with elective craniotomy surgery. This study was divided into two groups of subjects, group A with seven craniotomy subjects with general anesthesia and group B with seven craniotomy subjects combined with scalp block using ropivacaine 0.5%. Data collected then analyzed with SPSS. We found a decrease in MAP (Mean Arterial Pressure) and heart rate in the scalp block group during scalp incision (MAP p=0.002; HR p=0.029), periosteal contact (MAP p=0.025; HR p=0.039) significantly, as well as the use of fentanyl during surgery was significantly decreased (p=0.0001). General anesthesia with scalp block is more effective in reducing the increase in MAP, heart rate and fentanyl consumption during craniotomy.
ACHIEVEMENT OF COMPETENCY DURING PEDIATRIC ROTATION OF ANESTHESIOLOGY RESIDENTS ACCORDING TO THE EDUCATIONAL STANDARD OF ANESTHESIOLOGY IN FACULTY OF MEDICINE AIRLANGGA UNIVERSITY Meilissa Eka Susanti; Arie Utariani; Elizeus Hanindito
JURNAL WIDYA MEDIKA Vol 7, No 1 (2021): April
Publisher : FAKULTAS KEDOKTERAN UNIVERSITAS KATOLIK WIDYA MANDALA SURABAYA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33508/jwm.v7i1.2781

Abstract

Background: The advancement and development of science and technology in the field anesthesiology and intensive therapy, has become the basis for the need of quality national guideline that is ethically and professionally accountable. This operational guideline can serve as a national guideline in providing anesthesia and intensive therapy services to patients. Until today, there is still no standardize educational evaluation for the pediatric division of anesthesiology to assess whether it is following the expected standards. Aim: To analyze the competency of anesthesiology residents in the pediatric division based on logbook according to the type of cases and procedures, and the number of patients based on the standard curriculum of the pediatric division of anesthesiology Surabaya. Methods: This study was an observational study with retrospective design, evaluating the competency of anesthesiology residents of Airlangga University in pediatric rotation according to the type of cases and procedures, and the number of patients treated and recorded in residents’ logbook based on the standard curriculum of the pediatric division of anesthesiology Surabaya. Data collection was performed by taking secondary data from April 2018-April 2020. Result: Median total of eletive cases during rotation and emergency cases during shift treated by anesthesiology resident of pediatric division was 9 (5-13) neonates, 35 (26-44) infants, and 56 (48-62) children. Target of neonates cases was achieved by 35%, infants by 100%, and children by 95% residents. Target of caudal anesthesia was achieved by 100%, inhalation induction by 55%, and IV line insertion by 100%. No resident achieved target for CVC insertion. Conclusion: A more formal and comprehensive guideline to standardize log case recording can be beneficial as it can evaluate residents based on the data collected electronically.
Effects Of Regional Scalp Block With Ropivacaine 0.5% Preincision As A Preemptive Analgesia After Craniotomy Surgery R. Muhammad Aviv Pasa; Christrijogo Soemartono; Soni Sunarso Sulistiawan; Arie Utariani
JURNAL WIDYA MEDIKA Vol 6, No 1 (2020): April
Publisher : FAKULTAS KEDOKTERAN UNIVERSITAS KATOLIK WIDYA MANDALA SURABAYA

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (889.858 KB) | DOI: 10.33508/jwm.v6i1.2500

Abstract

Studies reported that more than 55% of patients complained of moderate to severe pain up to 48 hours post craniotomy. Fentanyl is the drug of choice to manage acute pain with disadvantages. Regional scalp block (RSB) technique using local anesthesia may be an alternative for post craniotomy pain management. Objective: to analyze the effects of RSB using ropivacaine 0.5% before incision compared to general anesthesia alone on the pain scale and opioid requirements 24-hour post craniotomy. This is a single-blind randomized experimental study. 14 Subjects were divided into two intervention groups. Patients were 18–64 years, GCS (Glasgow Coma Scale) 15, physical status ASA (American Society of Anesthesiologists) 1–3, undergoing craniotomy. In this study, the mean of fentanyl dose in RSB group was smaller than the group without RSB, which was statistically significant (p=0.017). Pain was also significantly reduced in RSB group at 30 minutes (p=0.009), 1 hour (p=0.003), 2 hours (p=0.003), 4 hours (p=0.001), 8 hours (p=0.050), and 12 hours (p=0.003) post-surgery. There was no difference in pain scale between the two groups at 24 hours post-surgery (p=0.393). RSB using ropivacaine 0.5% preincision is more effective in reducing pain scale up to 12 hours and also reduced the requirement of fentanyl within 24-hours post craniotomy compared to general anesthesia alone.