Garuda - Garba Rujukan Digital

Efek perilaku mengunyah terhadap Indeks Massa Tubuh Rio Guntur Maharsi; Kartika Indah Sari; Rosiliwati Wihardja; Indrati Soedjarwo; Nanan Nur'aeny
Padjadjaran Journal of Dental Researchers and Students Vol 2, No 2 (2018): Oktober 2018
Publisher : Fakultas Kedokteran Gigi Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/pjdrs.v2i2.21434

Pendahuluan: Perilaku mengunyah setiap orang memerlukan waktu mengunyah yang berbeda. Waktu mengunyah tersebut menggambarkan seberapa cepat seseorang untuk mengunyah. Semakin cepat mengunyah maka orang tersebut memiliki kecenderungan untuk mengalami kelebihan berat badan. Penelitian ini bertujuan untuk mengetahui hubungan antara perilaku mengunyah (kecepatan mengunyah) terhadap berat badan. Metode: Empat puluh delapan orang mahasiswa Fakultas Kedokteran Gigi Universitas Padjadjaran terpilih untuk mengikuti penelitian ini. Setiap subjek mengikuti pengukuran tinggi badan dan berat badan. Subjek penelitian diminta melakukan puasa 8 jam sebelumnya, tes makan dilakukan pada pagi hari pukul dengan porsi makanan seberat 430 gram. Pengukuran waktu makan dilakukan dengan menggunakan stopwatch. Data dianalisis dengan menggunakan uji korelasi rank Spearman. Hasil: terdapat hubungan yang bermakna (p<0,05; p=0,031) dengan koefisien korelasi positif (0,311) antara kecepatan pengunyahan dengan indeks massa tubuh. Simpulan: Korelasi kecepatan pengunyahan berbanding lurus dengan Indeks Massa Tubuh. Semakin tinggi kecepatan mengunyah maka semakin tinggi kecenderungan seseorang memiliki IMT di atas rata-rata.Kata kunci: Kecepatan pengunyahan, Indeks Massa Tubuh, obesitas

Profil lesi stomatitis aftosa rekuren pada pasien di instalasi Ilmu Penyakit Mulut RSGM Unpad periode 2014-2015 Nurul Mukhliza Safely; Nanan Nur'aeny; Wahyu Hidayat
Padjadjaran Journal of Dental Researchers and Students Vol 1, No 2 (2017): Oktober 2017
Publisher : Fakultas Kedokteran Gigi Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/pjdrs.v2i1.22112

Pendahuluan: Stomatitis Aftosa Rekuren (SAR) merupakan penyakit mulut yang sangat sering terjadi pada masyarakat. SAR memiliki gambaran klinis berupa lesi ulserasi kecil berbentuk bulat atau oval dengan tepi kemerahan dan batas yang jelas serta dasar ulser berwarna putih atau kekuningan. Prevalensi SAR pada populasi dunia bervariasi antara 5% sampai 66% dengan rata-rata 20%. SAR diklasifikasikan dalam 3 tipe yaitu lesi minor, mayor, dan herpetiform; lesi sering ditemukan di mukosa labial, biasa diberikan terapi farmakologi berupa anti inflamasi topikal, serta membutuhkan masa penyembuhan 7-10 hari. Tujuan penelitian ini adalah mengetahui profil lesi SAR pada pasien di Instalasi Ilmu Penyakit Mulut Rumah Sakit Gigi dan Mulut Universitas Padjadjaran (RSGM Unpad) periode tahun 2014-2015. Metode: Jenis penelitian yang dilakukan bersifat deskriptif dari penelusuran data sekunder. Sampel penelitian yaitu rekam medis pasien dengan diagnosa SAR di RSGM Unpad periode 2014-2015. Hasil: Kasus SAR ditemukan sejumlah 47 kasus dari sejumlah 132 keseluruhan kasus penyakit mulut di instalasi penyakit mulut RSGM Unpad periode 2014-2015. SAR sebagian besar terjadi pada pasien dengan jenis kelamin perempuan daripada laki-laki, serta paling banyak ditemukan pada usia 20-29 tahun. Simpulan: Profil lesi SAR lebih banyak ditemukan tipe SAR minor, berlokasi di mukosa labial, dengan lama penyembuhan 7-14 hari dan penatalaksanaan farmakologi yang paling sering diberikan adalah topikal anti inflamasi kortikosteroid.Kata Kunci : Profil lesi oral, stomatitis aftosa rekuren, ilmu penyakit mulut

Korelasi antara tingkat kecukupan gizi dengan indeks massa tubuh siswa sekolah dasar kelas 4, 5, dan 6Correlation between nutritional adequacy levels with body mass index of elementary school students grades 4, 5, and 6 Dida Akhmad Gurnida; Nanan Nur'aeny; Dzulfikar Djalil Lukmanul Hakim; Fransisca Sri Susilaningsih; Dewi Marhaeni Diah Herawati; Iis Rosita
Padjadjaran Journal of Dental Researchers and Students Vol 4, No 1 (2020): April 2020
Publisher : Fakultas Kedokteran Gigi Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/pjdrs.v4i1.25763

Pendahuluan: Usia anak merupakan masa yang penting dalam kehidupan manusia dengan ditandai oleh proses tumbuh kembang. Pertumbuhan dan perkembangan anak perlu didukung oleh asupan makanan yang seimbang. Salah satu parameter peisnilaian status gizi adalah indeks massa tubuh (IMT). Tujuan penelitian ini adalah untuk menganalis korelasi antara tingkat asupan dan kecukupan gizi dengan IMT. Metoda: Jenis penelitian analitik observasional dengan desain korelasional dilaksanakan di SDN 1 Tempuran Karawang pada Bulan Oktober 2018. Subjek penelitian adalah siswa kelas 4, 5 dan 6 sebanyak 62 anak yang dilakukan secara konsekutif. Pengumpulan data melalui pengukuran berat badan, tinggi badan dan pengisian form food frequency questionnaire (FFQ). Analisis data dengan uji korelasi pearson product moment Hasil: Kebanyakan subjek adalah siswa perempuan (55%), berusia 11 tahun (45%), IMT normal (47%), tingkat kecukupan energi dan zat gizi defisit tingkat berat (65%). Uji korelasi antara tingkat kecukupan energi, protein, karbohidrat dan lemak dengan IMT menunjukkan korelasi lemah dalam arah negatif dan tidak signifikan yaitu -0,200 (p= 0,120), -0,188 (p=0,143), -0,162 (p=0,209), dan -0,179 (p=0,163) secara berurutan. Simpulan: Tingkat kecukupan gizi yang terdiri dari energi, protein, karbohidrat dan lemak dengan IMT menunjukkan korelasi lemah dalam arah negatif pada siswa kelas 4,5 dan 6.Kata kunci: Indeks massa tubuh, korelasi, siswa sekolah dasar, tingkat kecukupan gizi. ABSTRACTIntroduction: Childhood age is an important period in human life marked by the process of growth and development. Growth and development of children need to be supported by balanced food intake. One parameter for assessing nutritional status is the body mass index (BMI). The purpose of this study was to analyse the correlation between the level of intake and nutritional adequacy with BMI. Method: This study was an observational analytic study with a correlational design carried out at Tempuran 1 Public Elementary School Karawang in October 2018. The research sample consisted of 62 students from grade 4, 5, and 6, taken by consecutive sampling. Data collected through measurements of body weight, height, and filling out the food frequency questionnaire (FFQ) form. Data analysis was performed with the Pearson product-moment correlation test. Results: Female students (55%), aged 11 (45%), normal BMI (47%), the level of energy and nutrient adequacy showed a severe deficit level (65%) and the correlation test between the level of adequacy energy, protein, carbohydrate and fat with BMI showed a weak correlation in a negative direction and not significant, namely -0.200 (p = 0.120); -0.188 (p = 0.143); -0.162 (p = 0.209), and -0.179 (p = 0.163) ) sequentially. Conclusion: The level of nutritional adequacy of grades 4, 5, and 6 elementary students consisting of energy, protein, carbohydrates, and fats shows a weak correlation in a negative direction with BMI.Keywords: Nutrition adequacy level, body mass index, students, elementary school.

Faktor risiko dan tatalaksana kandidiasis oral pada pasien dengan drug reaction with eosinophilia and systemic symptoms (DRESS)Risk factors and management of oral candidiasis in drug reaction with eosinophilia and systemic symptoms (DRESS) patients Embun Manja Sari; Nuri Fitriasari; Nanan Nur'aeny
Jurnal Kedokteran Gigi Universitas Padjadjaran Vol 34, No 1 (2022): April 2022
Publisher : Fakultas Kedokteran Gigi Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/jkg.v34i1.33531

Pendahuluan: Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) adalah reaksi obat yang jarang terjadi, tetapi menimbulkan reaksi klinis yang berat, berupa demam, erupsi kulit, dan keterlibatan organ internal. Terapi medikasi untuk pasien DRESS berupa pemberian kortikosteroid high potent memiliki faktor risiko terjadinya kandidiasis oral selain faktor gangguan imunitas secara sistemik akibat DRESS. Penulisan laporan kasus bertujuan untuk memaparkan faktor risiko dan tatalaksana kandidiasis oral pada pasien DRESS. Laporan kasus: Seorang laki-laki berusia 51 tahun dirawat selama 14 hari dengan diagnosis DRESS oleh bagian Dermatologi dan Venereologi Rumah Sakit Hasan Sadikin Bandung. Terapi intravena yang diberikan adalah Deksametason 20 gram/hari, Vitamin K 3x1 ampul/hari, Omeprazole 1x40 gram/hari, dan Siprofloksasin 2x400 gram/hari. Terapi per oral yang diberikan adalah: Cetirizine 1x10 gram/hari, Curcuma 3x1 kapsul/hari, Asam folat 1x1 tab/hari, Asetilsistein 2x2 mg/hari, serta Callos 1x500 mg/hari. Pasien kemudian dikonsulkan ke bagian Ilmu Penyakit Mulut karena memiliki keluhan sakit pada rongga mulut, tenggorokan, dan bibir sejak 3 hari di RS. Riwayat sariawan berulang disangkal. Pasien tidak pernah menyikat gigi selama rawat inap. Tatalaksana kandidiasis oral diberikan Nystatin in oral suspension 4x200.000 IU/hari, Chlorhexidine digluconate 0,12%, asam hialuronat, NaCl 0,9%, serta Mikonazol krim 2% dan racikan deksametason salep 0,002% diberikan terkait lesi pada bibir dan dioleskan pada sudut mulut. Simpulan: Faktor risiko kandidiasis oral pada pasien DRESS adalah penggunaan kortikosteroid secara sistemik, gangguan imun terkait DRESS, dan kebersihan rongga mulut yang buruk. Tatalaksana kandidiasis oral diberikan adalah antifungal dan antiseptik.Kata kunci: drug reaction with eosinophilia and systemic symptoms; faktor risiko; kandidiasis oral ABSTRACTIntroduction: Drug reaction with eosinophilia and systemic symptoms (DRESS) is a rare drug reaction but causes severe clinical reactions in the form of fever, skin eruptions, and involvement of internal organs. Medical therapy for DRESS patients in the form of high potent corticosteroids has a risk factor for oral candidiasis and systemic immune disorders. This case report aimed to describe the risk factors and management of oral candidiasis in DRESS patients. Case report: A 51-year-old male was treated for 14 days with a diagnosis of DRESS by the Department of Dermatology and Venereology of Hasan Sadikin Hospital, Bandung. Intravenous therapy administered was 20 grams/day of Dexamethasone, 3x1 ampoules/day of Vitamin K, 1x40 grams/day of Omeprazole, and 2x400 grams/day of Ciprofloxacin. Oral therapy was 1x10 grams/day of Cetirizine, 3x1 capsules/day of Curcuma, 1x1 tab/day of folic acid, 2x2 mg/day of Acetylcysteine, and 1x500 mg/day of Callos. The patient was then referred to the Department of Oral Medicine because of complaints of pain in the oral cavity, throat, and lips after hospitalisation for three days. History of recurrent thrush was denied. The patient never brushed his teeth during hospitalisation. The management of oral candidiasis was the administration of Nystatin in oral suspension with the dose of 4x200,000 IU/day, 0.12% Chlorhexidine digluconate, hyaluronic acid, 0.9% NaCl, and 2% topical Miconazole, and a mixture of 0.002% dexamethasone ointment, which was given related to lesions on the lips, and topically administered in the corner of the lips. Conclusion: The risk factors for oral candidiasis in DRESS patients are systemic use of corticosteroids, DRESS-related immune disorders, and poor oral hygiene. The management of oral candidiasis is antifungal and antiseptic.Keywords: drug reaction with eosinophilia and systemic symptoms; oral candidiasis, risk factors

Manajemen pendarahan gingiva akibat pansitopenia pada pasien dengan suspek anemia aplastikManagement of pancytopenia gingival bleeding in patients with suspected aplastic anaemia Fika Faradillah Drakel; Dewi Zakiawati; Nanan Nur'aeny
Jurnal Kedokteran Gigi Universitas Padjadjaran Vol 34, No 1 (2022): April 2022
Publisher : Fakultas Kedokteran Gigi Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/jkg.v34i1.33530

Pendahuluan: Pansitopenia merupakan suatu keadaan yang ditandai oleh adanya anemia, leukopenia serta trombositopenia akibat gangguan pada sumsum tulang yang menyebabkan proses produksi sel hematopoietik menjadi tidak normal. Salah satu manifestasi rongga mulut pada pansitopenia adalah pendarahan gingiva. Perawatan pendarahan gingiva telah banyak dilakukan dengan pemberian obat kumur feracrylum 1%, atau dengan cara mengompres lokasi pendarahan menggunakan kain kasa yang ditetes dengan lidokain. Laporan kasus ini bertujuan untuk memaparkan manajemen perawatan pendarahan gingiva pada pasien pansitopenia dengan suspek anemia aplastik. Laporan kasus: Seorang pria berusia 50 tahun dengan keluhan lemah badan, demam, melena dan gingiva berdarah sejak dua tahun yang lalu, tidak disertai rasa sakit pada gingiva dan area lainnya dalam rongga mulut. Pasien ini dirawat bersama oleh bagian Ilmu Penyakit Dalam dan Ilmu Penyakit Mulut. Pemeriksaan rongga mulut menunjukkan adanya pendarahan pada gingiva regio rahang atas kiri dan bawah kiri. Hasil pemeriksaan penunjang menunjukkan hemoglobin: 7,1g/dL, hematokrit: 18%, eritrosit 1,46x104/μL, leukosit 2,5x103/μL, trombosit 7,2x104/μL. Hasil pemeriksaan sumsum tulang yang pertama sulit dinilai. Transfusi darah diberikan dua labu perhari selama enam hari, area pendarahan pada gingiva dilakukan kompres menggunakan asam traneksamat selama satu sampai tiga menit kemudian dilanjutkan kumur asam traneksamat selama satu menit. Hasil setelah terapi selama 6 hari, tidak ditemukan lagi pendarahan pada gingiva. Simpulan: Terapi lokal kompres dan kumur asam traneksamat dapat menjadi pilihan perawatan yang sangat efektif untuk menghentikan pendarahan gingiva pada pasien pansitopenia, selain terapi transfusi darah tetap dilakukan untuk mengembalikan kadar normal komponen dalam darah.Kata kunci: anemia aplastik; asam traneksamat; pansitopenia; pendarahan gingiva ABSTRACTIntroduction: Pancytopenia is a condition characterised by anaemia, leukopenia and thrombocytopenia due to disorders of the bone marrow that cause the production process of hematopoietic cells to become abnormal. One of the oral manifestations of pancytopenia is gingival bleeding. Gingival bleeding treatment has been mainly carried out by administering 1% Feracrylum mouthwash or compressing the bleeding site using gauze dripped with lidocaine. This case report aimed to describe the management of pancytopenia gingival bleeding in patients with suspected aplastic anaemia. Case report: A 50-year-old male with the chief complaint of weakness, fever, melena, and gingival bleeding two years prior, without gingival pain and other oral cavity areas. This patient was treated simultaneously by the Department of Internal Medicine and Oral Medicine. Examination of the oral cavity revealed bleeding in the left maxillary and left mandibular gingiva. Investigation results showed haemoglobin level was 7.1g/dL, hematocrit 18%, erythrocytes 1.46x104/μL, leukocytes 2.5x103/μL, and platelets 7.2x10⁴/μL. However, the first bone marrow examination result was still challenging to assess. Therefore, two flasks of blood transfusions were given per day for six days. The bleeding gingival area was compressed using tranexamic acid for one to three minutes, followed by tranexamic acid gargling for one minute. After six days of therapy, no more gingival bleeding was detected. Conclusion: Local compress therapy and tranexamic acid gargling can be effective treatment options to stop gingival bleeding in pancytopenia patients; blood transfusion therapy needs to remain carried out to restore normal levels of blood components.Keywords: aplastic anaemia; tranexamic acid; pancytopenia; gingival bleeding

Suplementasi mikronutrien pada pasien eritema multiforme dengan penurunan kualitas eritrositMicronutrient supplementation in erythema multiforme patients with decreased erythrocyte quality I Nyoman Gede Juwita Putra; Suniti Suniti; Nanan Nur'aeny; Indah Suasani Wahyuni
Jurnal Kedokteran Gigi Universitas Padjadjaran Vol 32, No 3 (2021): Februari 2021 (Suplemen 2)
Publisher : Fakultas Kedokteran Gigi Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/jkg.v32i3.31871

Pendahuluan: Eritema multiforme (EM) adalah penyakit peradangan akut yang merupakan reaksi hipersensitivitas pada mukokutan dan jarang ditemukan. Gambaran klinis EM berupa lesi erosi-ulseratif dan memiliki tendensi perdarahan. Kualitas eritrosit yang menurun dapat mempengaruhi proses penyembuhan penyakit ini, namun hal ini dapat diatasi dengan pemenuhan asupan mikronutrien. Tujuan laporan kasus ini untuk memaparkan hasil terapi suplementasi mikronutrien yang diberikan untuk tatalaksana EM pada pasien yang mengalami penurunan kualitas eritrosit. Laporan kasus: Seorang wanita berusia 21 tahun mengeluhkan perdarahan bibir dan sariawan dalam rongga mulut, terasa sakit sejak 3 minggu sebelumnya. Riwayat keluhan yang sama pernah dialami 7 tahun sebelumnya. Pemeriksaan ekstraoral memperlihatkan krusta hemoragik pada bibir, sedangkan hasil pemeriksaan intraoral menunjukkan ulserasi multipel pada hampir seluruh mukosa rongga mulut. Hasil pemeriksaan laboratorium menunjukkan adanya penurunan kualitas eritrosit berdasarkan parameter Mean Corpuscular Volume (MCV), Mean Cell Hemoglobin (MCH), dan Mean Cell Hemoglobin Concentration (MCHC); peningkatan jumlah eritrosit; dan eosinofil pada borderline atas, serta anti HSV-I IgG non-reaktif. Diagnosis pasien adalah eritema multiforme dengan riwayat stomatitis aftosa rekuren (SAR). Tatalaksana farmakologis diberikan asam folat dan vitamin B12 sebagai suplementasi mikronutrien. Diberikan pula chlorhexidine digluconate 0,12% mouthrinse sebagai antiseptik, dan petroleum jelly untuk pelembab bibir. Lesi oral pasien sembuh setelah 2 minggu terapi. Simpulan: Suplementasi mikronutrien berperan penting dalam mempercepat penyembuhan lesi mukosa oral pada pasien eritema multiforme yang mengalami penurunan kualitas eritrosit. Mikronutrien berupa asam folat dan vitamin B12 berperan penting dalam sintesis DNA eritrosit, pembelahan sel, dan perbaikan jaringan. Kata kunci: Mikronutrien, eritema multiforme, kualitas eritrosit. ABSTRACTIntroduction: Erythema multiforme (EM) is an acute inflammatory disease as a hypersensitivity reaction to mucocutaneous and is rarely found. The clinical feature of EM is an erosive-ulcerative lesion with a tendency of bleeding. Decreasing erythrocyte quality can affect its healing process, although able to be overcome by fulfilling the micronutrient intake. The purpose of this case report was to describe the results of micronutrient supplementation therapy given in the management of EM patients with decreasing erythrocyte quality. Case report: A 21-year-old woman complained of lip bleeding and oral thrush, which felt pain three weeks prior. A similar complaint history had been experienced in the previous seven years. Extraoral examination revealed haemorrhagic crusting on the lips, whereas intraoral examination showed multiple ulcerations of almost the entire oral mucosa. Laboratory examination results showed a decreasing erythrocyte quality based on the parameters of Mean Corpuscular Volume (MCV), Mean Cell Haemoglobin (MCH), and Mean Cell Haemoglobin Concentration (MCHC); an increasing number of erythrocytes and eosinophils in the upper borderline, as well as non-reactive anti-HSV-I IgG. The patient was diagnosed with erythema multiforme with a history of recurrent aphthous stomatitis (RAS). Pharmacological management was performed by given folic acid and vitamin B12 as micronutrient supplementation. Also, given a 0.12% chlorhexidine digluconate mouth rinse as an antiseptic and petroleum jelly for lip balm. The patient’s oral lesions resolved after two weeks of therapy. Conclusion: Micronutrient supplementation plays an essential role in accelerating the oral mucosal lesions healing in erythema multiforme patients with decreasing erythrocyte quality. Micronutrients in folic acid and vitamin B12 play an important role in erythrocyte DNA synthesis, cell division, and tissue repair.Keywords: Micronutrient, erythema multiforme, erythrocyte quality.

Tatalaksana infeksi herpes simpleks virus tipe-1 dan necrotizing ulcerative stomatitis pada anak dengan anemia aplastikManagement of type-1 herpes simplex virus infection and necrotising ulcerative stomatitis in children with aplastic anaemia Yannie Febby Martina Lefaan; Wahyu Hidayat; Nanan Nur'aeny
Jurnal Kedokteran Gigi Universitas Padjadjaran Vol 33, No 3 (2022): Maret 2022 (Suplemen 3)
Publisher : Fakultas Kedokteran Gigi Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/jkg.v33i3.30642

ABSTRAKPendahuluan: Necrotizing ulcerative stomatitis (NUS) merupakan penyakit inflamasi pada rongga mulut, ditandai oleh ulser nekrosis akut, berkembang cepat serta menyebabkan kerusakan masif pada jaringan. NUS dapat berkembang dari kondisi necrotizing ulcerative gingivitis (NUG) dan necrotizing ulcerative periodontitis (NUP). NUS dapat disertai infeksi lain, salah satunya infeksi herpes simplex tipe 1 (HSV-1). Infeksi HSV-1 dan NUS pada anak dengan anemia aplastik jarang ditemukan. Anemia aplastik merupakan kelainan hematologi, ditandai dengan hipoplastik/aplasia sumsum tulang dan pansitopenia, sehingga menurunkan resistensi host terhadap infeksi. Gingivostomatitis herpetik primer memudahkan perkembangan bakteri komensal seperti bakteri Fusiform, Spirochetes dan Pseudomonas aeruginosa menjadi patogen pada kondisi imunosupresif sehingga meningkatkan progresivitas penyakit periodontal menjadi NUS. Tujuan laporan kasus ini adalah menjelaskan tatalaksana infeksi HSV-1 dan NUS pada anak dengan anemia aplastik. Laporan kasus: Seorang anak perempuan usia 3 tahun dengan diagnosis anemia aplastik dan febrile neutropenia, dirujuk oleh divisi Hematologi-onkologi anak Rumah Sakit Dr. Hasan sadikin (RSHS) Bandung dengan keluhan pembengkakan pada bibir dan stomatitis. Hasil pemeriksaan darah menunjukan adanya pansitopenia dan pemeriksaan anti HSV-1 IgG reaktif. Diagnosis terkait kondisi bibir dan mulut pasien adalah Infeksi HSV-1 dan NUS. Tatalaksana yang dilakukan adalah debridement dengan Hidrogen peroksida 1,5% (H2O2 1,5%), kontrol plak dengan chlorhexidine digluconate 0,12% dan multivitamin. Pembengkakan mulai membaik setelah 3 hari debridement serta memberikan hasil yang signifikan setelah 1 bulan perawatan. Simpulan: Tatalaksana berupa peningkatan oral hygiene dan terapi antiseptik dapat memperbaiki kondisi infeksi HSV-1 dan NUS, khususnya pada pasien dengan kondisi imunosupresif seperti anemia aplastik.Kata kunci: febrile neutropenia; stomatitis; herpes simpleks; anemia; spirochetes ABSTRACTIntroduction: Necrotising ulcerative stomatitis (NUS) is an inflammatory disease of the oral cavity, characterised by acute necrotising ulcers, proliferating, and causing massive tissue damage. NUS can be developed from necrotising ulcerative gingivitis (NUG) and necrotising ulcerative periodontitis (NUP). NUS can be accompanied by other infections, such as herpes simplex type 1 (HSV-1) infection. However, HSV-1 and NUS infections in children with aplastic anaemia are rare. Aplastic anemia is a haematological disorder characterised by hypoplastic/bone marrow aplasia and pancytopenia, reducing the host's resistance to infection. Primary herpetic gingivostomatitis facilitates the development of commensal bacteria such as Fusiform bacteria, Spirochetes and Pseudomonas aeruginosa to become pathogens under immunosuppressive conditions, thereby increasing the progression of periodontal disease to NUS. This case report aims to describe the management of HSV-1 and NUS infections in children with aplastic anemia. Case report: A 3-year-old female child diagnosed with aplastic anaemia and febrile neutropenia was referred by the paediatric haematology-oncology division of Dr Hasan Sadikin Hospital (RSHS) Bandung with complaints of swelling of the lips and stomatitis. Blood test results showed pancytopenia and reactive anti-HSV-1 IgG examination. The diagnosis related to the patient's lips and mouth condition was HSV-1 and NUS infection. The treatment is debridement with 1.5% hydrogen peroxide (H2O2 1.5%), plaque control with 0.12% chlorhexidine digluconate and multivitamins. After three days of debridement, the swelling started to improve and gave significant results after one month of treatment. Conclusion: Management of improving oral hygiene and antiseptic therapy can improve the condition of HSV-1 and NUS infections, especially in patients with immunosuppressive conditions such as aplastic anemia.Keywords: febrile neutropenia; stomatitis; herpes simplex; anaemia; spirochetes

Nutritional status of vitamin B12 on small group of dental students based on food frequency questionnaire Izzatul Syafiqah; Nanan Nur'aeny; Erna Herawati
Padjadjaran Journal of Dentistry Vol 28, No 3 (2016): November 2016
Publisher : Faculty of Dentistry Universitas Padjadjaran

Introduction: Vitamin B12 plays an important role in general cell metabolism. Vitamin B12 also essential for normal hematopoietic, importance in maintaining the integrity of nervous system and formation of nervous system. Even though vitamin B12 is essential for good health, some people may not be getting enough intake of vvitamin B12. The purpose of this research is to get information about the nutritional status of vitamin B12 on dental students based on food frequency questionnaire. Methods: Method used in this research were descriptive non experimental of 30 dental students from Faculty of Dentistry in Universitas Padjadjaran. All samples were given the food frequency questionnaire and recorded the amount of food were taken within 7 days. The consumption of vitamin B12 daily were calculated by using Nutrisurvey software. Results: Among 30 students, there were 7 students who were in lack of consumption of vitamin B12, 14 students or almost half of them who were in normal level and 9 students who were in high level of Vitamin B12 consumption. Conclusion: The Nutritional Status of Vitamin B12 on Small Group of Dental Students Based on Food Frequency Questionnaire were mostly in normal level.

Serum IL-6 levels of atopic patients with recurrent aphthous stomatitis (RAS) Nanan Nur'aeny; Irna Sufiawati; Oki Suwarsa; Dida Akhmad Gurnida
Padjadjaran Journal of Dentistry Vol 31, No 1 (2019): March 2019
Publisher : Faculty of Dentistry Universitas Padjadjaran

Introduction: Atopy is a genetic tendency of allergic condition with specific clinical manifestations such as atopic dermatitis (AD), allergic rhinitis (AR), and bronchial asthma (BA). Atopic individuals might experience other health problems that coincide with atopic manifestations, including the appearance of recurrent aphthous stomatitis (RAS) which is an oral mucosal disease that can also be influenced by allergies. This study was aimed to be the preliminary study regarding the level of IL-6 serum in atopic patients who were also having RAS. Methods: Thirty subjects were recruited and grouped into three groups with ten subjects each were group of atopic (dermatitis, allergic rhinitis, or bronchial asthma) with RAS, atopic without RAS, and control. Blood specimens were obtained with an approved institutional board review protocol. This research was cross-sectional research with consecutive sampling method conducted at Dr Hasan Sadikin Hospital Bandung. Results: There were significant differences in IL-6 log levels in all three groups (p < 0.001). The higher IL-6 levels in the group of atopic with RAS might be due to the influence of atopy because this condition can increase the acute inflammation of RAS. IL-6 is a pro-inflammatory marker found in the circulation of atopic and RAS patients. Conclusion: Serum IL-6 levels in the group of atopic patients with RAS is higher than in other groups. Keywords: Serum, IL-6, atopic, recurrent aphthous stomatitis

Distribution of oral ulceration cases in Oral Medicine Integrated Installation of Universitas Padjadjaran Dental Hospital Dewi Zakiawati; Nanan Nur'aeny; Riani Setiadhi
Padjadjaran Journal of Dentistry Vol 32, No 3 (2020): November 2020
Publisher : Faculty of Dentistry Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/pjd.vol32no3.23664

Introduction: Oral ulceration defines as discontinuity of the oral mucosa caused by the damage of both epithelium and lamina propria. Among other types of lesions, ulceration is the most commonly found lesion in the oral mucosa, especially in the outpatient unit. Oral Medicine Integrated Installation (OMII) Department in Universitas Padjadjaran Dental Hospital serves as the centre of oral health and education services, particularly in handling outpatient oral medicine cases. This research was the first study done in the Department which aimed to observe the distribution of oral ulceration in OMII Department university Dental Hospital. The data is essential in studying the epidemiology of the diseases. Methods: The research was a descriptive study using the patient’s medical data between 2010 and 2012. The data were recorded with Microsoft® Excel, then analysed and presented in the table and diagram using GraphPad Prism® Results: During the study, the distribution of oral ulceration cases found in OMII Department was 664 which comprises of traumatic ulcers, recurrent aphthous stomatitis, angular cheilitis, herpes simplex, herpes labialis, and herpes zoster. Additionally, more than 50% of the total case was recurrent aphthous stomatitis, with a precise number of 364. Conclusion: It can be concluded that the OMII Department in university Dental Hospital had been managing various oral ulceration cases, with the most abundant cases being recurrent aphthous stomatitis.

Title

Found 16 Documents
Search

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Title Search

Found 16 Documents Search

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Title

Found 16 Documents
Search