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All Journal Jurnal Ilmiah Keperawatan (Scientific Journal of Nursing) Journal of Dedicators Community Berdikari: Jurnal Pengabdian Masyarakat Indonesia INDONESIAN JOURNAL OF MEDICAL LABORATORY SCIENCE AND TECHNOLOGY Community Development Journal Abdimas: Jurnal Pengabdian Masyarakat Universitas Merdeka Malang Community Development Journal: Jurnal Pengabdian Masyarakat International Islamic Medical Journal Journal of Health Community Service Wisanggeni : Jurnal Pengabdian Masyarakat
Handayani Handayani
Fakultas Kedokteran, Universitas Nahdlatul Ulama, Surabaya, Jawa Timur, Indonesia
Religion Arts Humanities Economics, Econometrics & Finance Education Health Professions Medicine & Pharmacology Nursing Public Health Social Sciences Other

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Journal : International Islamic Medical Journal

 1 
The Effects of Turmeric Infusion and Turmeric Juice (Curcuma Domestica) on The Staphylococcus Aureus Growth in Vitro Renny Novi Puspitasari; Handayani Handayani; Ratna Sofaria
Jurnal Medis Islam Internasional Vol 2 No 2 (2021): June
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/iimj.v2i2.2140

Abstract

Background: Turmeric is a plant that grows in tropical areas and functions as medicine. The chemical compounds contained in turmeric have a role as antioxidants, antimicrobials, anti-cancer, indigestion, smallpox, insect bites. The curcumin content in turmeric has antibacterial activity against various types of Gram negative, Gram positive, antiviral and anti-tumor bacteria. Essential oils can be used as antibacterial because they contain hydroxyl and carbonyl functional groups which are phenol derivatives. Flavonoids can interfere with cell wall formation with peptidoglycan transpeptidase activity which will break down cell walls and damage cell membranes so that important components such as proteins, nucleic acids, nucleotides will be lysis. Staphylococcus bacteria are normal flora on the skin, respiratory tract, and digestive tract of food in humans. These bacteria can cause disease when they reach 1,000,000 or 106 per gram, an amount sufficient to produce the toxin. S. aureus bacteria can cause various types of infections ranging from minor skin infections, food poisoning to systemic infections. The aim of our study was to analyze the effects of infusion and turmeric juice (Curcuma domestica val) on the growth of bacteria Staphylococcus aureus through invitro. Method: This study is a laboratory experimental study with the aim of analyzing turmeric infusion (Curcuma domestica val) and turmeric juice effect on the growth of staphylococcus aureus by invitro. This research was conducted in an integrated laboratory, FK UNUSA. The samples in this study were 4 replications per treatment. The independent variables in this study were turmeric infusion and turmeric juice (with a concentration of 10%, 30%, 50% while the dependent variable in this study was the growth of Staphylococcus aureus bacteria. Data analysis used was the one way ANOVA test and Pearson correlation to determine the effect of giving turmeric infusion and turmeric juice on the growth of bacteria staphylococcus aureus through invitro. Result: The average growth of bacteria in the turmeric infusion in group I (control), 10%, 30% and 50% of turmeric infusion was 4.89 ± 0.4425 log CFU / ml, 3.07 ± 0.61330 log CFU / ml, 2.99 ± 0.63986 log CFU. / ml and 3.02 ± 0.22650 log CFU / ml. The average growth of this bacteria in giving turmeric juice in group I (control), giving 10%, 30% and 50% turmeric infusion was 4.89 ± 0.04425 log CFU / ml, 4.40 ± 0.18355log CFU / ml, 3.10 ± 0.58926 log CFU / ml and 3.02 ± 0.38206 log CFU / ml. Conclusion: In this study, found that there was an effect of giving turmeric infusion and turmeric juice (Curcuma domestica val) on Staphylococcus aureus growth and there was an effect of giving multilevel doses of turmeric infusion and turmeric juice (Curcuma domestica val) on Staphylococcus aureus growth through invitro.
The Use of Antibiotics without a Prescription : a Literature Review Arie Kusumo Dewi; Handayani Handayani; Afira Febriani
Jurnal Medis Islam Internasional Vol 4 No 1 (2022): December
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/iimj.v4i1.3855

Abstract

Background : Infectious diseases are treated with antibiotics. Antibiotics are widely used because infectious diseases are so common. Even though antibiotics are purchased at pharmacies with a doctor's prescription, many antibiotics are currently being taken without a prescription. Resistance will develop if antibiotics are consumed without a doctor's prescription and not according to indications for administration. Objective : This study examines how people use antibiotics without a doctor's prescription. Methods : The author of this article uses a method related to the article's title by using some relevant literature from database  of  journals such  as  Google  Scholar. The discussion and findings of this study will assist  readers and  health professionals in analyzing how people use antibiotics without a prescription. Result : Based  on  the  findings  of  the  five studies,   journals discuss   the relationship between knowledge level and attitudes regarding the use of antibiotics without a prescription. This  literature  review  shows that most people of reproductive age consume antibiotics without a doctor's prescription to treat symptoms usually caused by non-bacterial pathogens. Conclusion : . One of the intervention approaches taken to restrict access is government control. Holistic interventions against those who sell antibiotics without a prescription are expected to significantly reduce the irresponsible use of antibiotics in the community
Drug Interactions in Coronary Heart Disease Patients : a Literature Review Elok Tamarah; Handayani Handayani; Andik Ferdiantoro
Jurnal Medis Islam Internasional Vol 4 No 1 (2022): December
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/iimj.v4i1.3856

Abstract

Background: Patients with coronary heart disease generally receive many drugs, such as hypercholesterolemia, antianginal, antiplatelet, anticoagulants, and medications for comorbid illnesses such as antihypertension and diabetes mellitus. Concomitant administration of several types of drugs may result in drug interactions. Objective : This study aims to figure out drug interactions that might occur in using combination drugs in patients with coronary heart disease. Methods: This article review uses the Google Scholar database, published 2017-2022. The keywords used were "coronary heart disease and drug interactions." The PRISMA flowchart is used to summarize the article selection process. Results: Administration of aspirin  with  clopidogrel  causes  a  moderate  synergistic  interaction,  whereas  administration  of antiplatelet agents with anticoagulants causes a significant synergistic interaction on bleeding. And the administration of  nifedipine  with  atorvastatin causes  a  synergistic  pharmacodynamic interaction. Conclusions: Drug interactions occur in patients with coronary heart disease, either synergistic or antagonistic pharmacodynamic interactions with minor, moderate, and significant classifications
The Relationship Of Anti-Inflammation Non Steroid Use Patterns With Side Effects In Patients Post Appendectomy At Jemursari Islamic Hospital Shafira Nur Lailia; Handayani Handayani; Aditya Bhayusakti; Agus Aan Adriansyah
Jurnal Medis Islam Internasional Vol 5 No 1 (2023): December
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/iimj.v5i1.4122

Abstract

Background: Appendicitis is a condition where there is acute inflammation of the vermiform appendix which causes patients to undergo surgery frequently. NSAIDs are given to patients after appendectomy surgery to relieve pain. Inappropriate pattern of NSAID use can cause drug side effects. Objective: This study aims to analyze the relationship between the pattern of use of non steroidal anti-inflammatory analgesics and drug side effects in post-appendectomy patients at Jemursari Hospital Surabaya in 2019-2020. Methods: This type of research is descriptive analytic with a cross sectional design. This study used 62 samples medical record of post-appendectomy patients in 2019-2020 who were given NSAID  therapy. Chi-Square Test and Fisher's Exact Test (p<0.05) was used to analyze the relationship between NSAID use patterns and side effects. Results: There was a relationship between the type of drug Mafenamic Acid 500mg with nausea, Ketorolac 30mg with hypotension, Ketorolac 90mg with dizziness, and Santagesic 500mg with dyspepsia (p<0.05). Administration of therapy with less dose was associated with hypotension (p<0.05). The duration of therapy for 4 days was associated with nausea, vomiting and duration of therapy for 5 days was associated with constipation and dyspepsia. Conclusion: The use of drugs (type of drug, accuracy of dose and duration of therapy) of NSAIDs in post-appendectomy patients is associated with drug side effects.
Co-Authors Aditya Bhayusakti Afira Febriani Agus Aan Adriansyah Akbar Reza Muhammad Algristian, Hafid Andik Ferdiantoro Arie Kusumo Dewi Ary Andini Athiyatul Ulya Bambang Edi Suwito Bintarti, Tri Wahyuni Budiarti, Rizqi Putri Nourma Chilyatuz Zahroh Dewi Masithah Dian Dakwatul Choiriya Diaz Syafrie Abdillah Ebeth Jeremy Selly Elok Tamarah Endah Budi Permana Putri Eppy Setiyowati Fitria Agustina Hafizh Auliyan Sodali Lea Maera Shanty Melky Malae Muhammad Raffli Rahayu Anggraini Ratna Sofaria Munir Renata Alya Ulhaq Renny Novi Puspitasari Retna Gumilang Retno Ayu Yuliastuti Retno Diah Putri Ekayanti Rizki Nurmalya Kardina Rofi’usyani Rofi’usyani Shafira Nur Lailia Yanis Kartini Youwan Tobing Lukiyono