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Journal : Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan

UJI AKTIVITAS ANTIOKSIDAN EKSTRAK ETANOL DAUN DAN KULIT BATANG KALANGKALA (Litsea angulata) ASAL KALIMANTAN SELATAN Eka Fitri Susiani; Revita Saputri
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 5 No 1 (2020): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (298.615 KB) | DOI: 10.36387/jiis.v5i1.406

Abstract

Antioxidants have an important role in inhibiting free radicals that trigger oxidative stress cells that cause degenerative diseases. Kalangkala (Litsea angulata) is a typical plant of Borneo which may have antioxidant activity. This study aims to determine the antioxidant activity of ethanol extract of leaves and stem bark of Kalangkala (L.angulata) from South Borneo. Extracts were investigated for antioxidant activity qualitatively and quantitatively using 2,2-diphenyl-1-picrylhydrazyl (DPPH). Qualitatively, the results of antioxidant assays from ethanol extract of leaves and stem bark showed that there were yellow spots with a purple background on the TLC plate. Quantitatively, the ethanol extract of Kalangkala leaves obtained IC50 values of 152.39 ppm, while the ethanol extract of Kalangkala stem bark obtained IC50 values of 85.33 ppm. Thus, it can be concluded that the leaves and stem bark of Kalangkala (L.angulata) have antioxidant activity.
AKTIVITAS FRAKSI ETIL ASETAT KULIT BUAH JERUK NIPIS (Citrus aurantifolia (Christ) Swing) SEBAGAI ANTIPIRETIK PADA MENCIT YANG DIINDUKSI VAKSIN DPT Satrio Wibowo Rahmatullah; Eka Fitri Susiani; Muhammad Reza Fahlevi; Guntur Kurniawan; Siti Nurhaliza Leyla
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 6 No 2 (2021): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (192.824 KB) | DOI: 10.36387/jiis.v6i2.740

Abstract

Lime (Citrus aurantifolia (Christm.) Swing) is one of the types of oranges containing elements of compounds that are beneficial, so widely used as traditional medicine. This research aims to know the antipyretic activity of ethyl acetate fraction peel of lime. Phytochemical screening test result fraction ethyl acetate lemon rind contains flavonoids, saponins, alkaloids and essential oils. Total of 25 mice were divided into 5 groups, group I negative control, group II positive control, group III,IV,V were given ethyl acetate fraction at a dose of 0,07%/gBW,, 0,105%/gBWand 0,14%/gBW. Based on the results of graph average temperatures decrease the dose that the third has antipyretic activity because it can lower the temperature and the largest decreased in temperature at a dose 0,14%/gBW. Based on the test result ANOVA obtained sig. value 0,000. which means there is a temperature difference of meaning between 5 group treatment. And on Independent Test Sample T-test between a positive control with a dose 0,14%/gBW the value of sig. 0,601 (> 0,05) which means there is no meaningful difference.