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All Journal JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA Jurnal Pengabdian Al-Ikhlas Borneo Journal Of Pharmascientech Jurnal Insan Farmasi Indonesia Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Borneo Journal of Pharmacy
Eka Fitri Susiani
Sekolah Tinggi Ilmu Kesehatan Borneo Lestari
Biochemistry, Genetics & Molecular Biology Chemistry Economics, Econometrics & Finance Education Engineering Health Professions Immunology & microbiology Medicine & Pharmacology Physics Public Health Social Sciences Other

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Journal : Borneo Journal of Pharmacy

 1 
Uji Aktivitas Antioksidan Ekstrak Etanol Buah dan Biji Buah Kalangkala (Litsea angulata) asal Kalimantan Selatan: Antioxidant Activity Test of Ethanolic Extract of Kalangkala (Litsea angulata) Fruits and Seeds from South Kalimantan Revita Saputri; Eka Fitri Susiani
Borneo Journal of Pharmacy Vol. 1 No. 2 (2018): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v1i2.370

Abstract

Free radicals are atoms or molecules, having one or more unpaired electrons. Increased production of free radicals can cause oxidative stress and cause many pathological conditions, e.g. cancers, heart diseases, and other diseases. The antioxidant can inhibit oxidative stress. Kalangkala (Litsea angulata) usually found in the South Kalimantan that can be used as an antioxidant. The study aimed to determine the antioxidant activity of ethanolic extract of Kalangkala fruits and seeds from South Kalimantan. Antioxidant activity was conducted qualitatively and quantitative uses the method DPPH. The result of the antioxidant activity of ethanolic extract of Kalangkala fruits and seeds qualitatively showed the presence of yellow spots on a purple background at Thin Layer Chromatography (TLC). The result of the activity of ethanolic extract of Kalangkala seeds quantitatively obtained IC50 value was 48.78 ppm and activity of ethanolic extract of Kalangkala fruits quantitatively obtained IC50 value was 243.14 ppm. Ethanolic extract of Kalangkala fruits and seeds from South Kalimantan has antioxidant activity.
Antidiarrheal Activity of Ethanolic Extract of Vernonia amygdalina Del Leaves againts Male Mice Induced by Oleum Ricini Karunita Ika Astuti; Lusiana Dwi Wulandari; Eka Fitri Susiani
Borneo Journal of Pharmacy Vol. 2 No. 1 (2019): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v2i1.707

Abstract

Leaves of Vernonia amygdalina Del. is one of the alternative plants that people use as antidiarrheal in Martapura, Banjar. The purpose of research to determine the antidiarrheal activity and the effectiveness of ethanolic extract of leaves against male mice. The negative control was given NaCMC 0.5% orally, positive control was given Loperamide HCl 0.005 mg/20 g orally, and groups of ethanolic extract of leaves were given dosages in 100 mg/kg BW, 200 mg/kg BW, and 400 mg/kg BW orally. After 1 hour of treatment, the groups were induced by Oleum ricini orally and were observed for 4 hours. Based on three parameters were frequency, weight, and consistency of diarrhea. From the results observation of that negative control, positive control, EEDA 100 mg/kg BW, 200 mg/kg BW, and 400 mg/kg BW for diarrhea frequency parameter was 7.4 ± 2.30; 2 ± 1.22; 5.8 ± 3.34; 6.2 ± 4.08; 2.4 ± 1.67; the weight parameter was 1.34 ± 0.43; 0.38 ± 0.29;0.66 ± 0.56; 0.57 ± 0.38; 0.49 ± 0.33 and then consistency of diarrhea with EEDA 400 mg/kg BW improved the consistency at 180 minutes compared to control group at 210 minutes. In conclusion, from all parameters of ethanolic extract of Vernonia amygdalina Del. leaves can give an antidiarrhea effect with optimum dosage is 400 mg/kg BW.
In Vitro Determination of Sun Protection Factor of Water Extract of Aerodramus fuciphagus from Central Kalimantan Dita Ayulia Dwi Sandi; Eka Fitri Susiani; I Ketut Adnyana; Pratiwi Wikaningtyas
Borneo Journal of Pharmacy Vol. 4 No. 2 (2021): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v4i2.1782

Abstract

Sunscreen is a cosmetic substance that has the ability to reflect or absorb sunlight actively. It can prevent skin irritation due to UV rays. One of the natural ingredients with a sunscreen effect is the Edible-nest swiftlet's (Aerodramus fuciphagus) nest (ESN). This study aimed to determine the value of the sun protective factor (SPF) of the ESN water extract. The ESN water extract solution with variation concentration, this is 2000, 2500, 5000, 6000, and 7000 ppm, were measured by spectrophotometric UV-Vis at wavelength 290-375 nm with 5 nm intervals to determine the value of SPF, percentage of erythema transmission (%Te), and percentage of pigmentation transmission (%Tp) of ESN water extract. The result showed that the ESN water extract's SPF values at the concentration 2000, 2500, 5000, 6000, and 7000 ppm were 7.80; 9.68; 18.75; 20.58; and 22.24. The value of %Te of each concentration were 15.60±0.19; 10.03±0.42; 1.24±0.04; 0.81±0.01 and 0.56±0.01. While the value of %Tp of each concentration was showed the sunblock category. In conclusion, the ESN water extract from Central Kalimantan at the concentration of 6000 ppm has potential in ultraviolet protection against the skin in the ultra category with sunblock category mechanism. Further, it can be developed into sunscreen cosmetics from natural ingredients.
Co-Authors Any Guntarti Azmi Yunarti Dea Permata Rezky Dita Ayulia Dwi Sandi Guntur Kurniawan Hafiz Ramadhan I Ketut Adnyana Karunita Ika Astuti Khairina Maida Kintoko, Kintoko Lusiana Dwi Wulandari Muhammad Reza Fahlevi Muhammad Reza Pahlevi Pratiwi Wikaningtyas Revita Saputri Risti Hadiyanti Satrio Wibowo Rahmatullah Siti Nurhaliza Leyla